Medical College of Wisconsin
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Binod Dhakal MD

Assistant Professor

Institution: Medical College of Wisconsin
Department: Medicine
Division: Hematology and Oncology - Medicine
Program: Hematology

Member of the Cancer Center


  • Revised-International Staging System (R-ISS) is Predictive and Prognostic for Early Relapse (<24 months) after Autologous Transplantation for Newly Diagnosed Multiple Myeloma (MM). (Gopalakrishnan S, D'Souza A, Scott E, Fraser R, Davila O, Shah N, Gale RP, Kamble R, Diaz MA, Lazarus HM, Savani BN, Hildebrandt GC, Solh M, Freytes CO, Lee C, Kyle RA, Usmani SZ, Ganguly S, Assal A, Berdeja J, Kanate AS, Dhakal B, Meehan K, Kindwall-Keller T, Saad A, Locke F, Seo S, Nishihori T, Gergis U, Gasparetto C, Mark T, Nieto Y, Kumar S, Hari P) Biol Blood Marrow Transplant 2018 Dec 20 PMID: 30579965 12/24/2018    
  • Outcomes of Reduced-Intensity Conditioning Allogeneic Hematopoietic Cell Transplantation Performed in the Inpatient versus Outpatient Setting. (Guru Murthy GS, Hari PN, Szabo A, Pasquini M, Narra R, Khan M, Abedin S, Chhabra S, Dhakal B, D'Souza A, Drobyski WR, Rizzo JD, Runaas L, Shah NN, Shaw B, Saber W, Fenske T, Hamadani M) Biol Blood Marrow Transplant 2018 Dec 18 PMID: 30572109 12/21/2018    
  • Direct HLA Genetic Comparisons Identify Highly Matched Unrelated Donor-Recipient Pairs with Improved Transplantation Outcome. (Vazirabad I, Chhabra S, Nytes J, Mehra V, Narra RK, Szabo A, Jerkins JH, Dhakal B, Hari P, Anderson MW) Biol Blood Marrow Transplant 2018 Dec 08 PMID: 30537549 12/12/2018    
  • Novel biomarkers in multiple myeloma. (Levin A, Hari P, Dhakal B) Transl Res 2018 11;201:49-59 PMID: 30301522 10/12/2018    
  • Risk, Outcomes, and Predictors of Infection in Lymphoma: A Nationwide Study. (Bhandari S, Pandey RK, Dahal S, Shahreyar M, Dhakal B, Jha P, Venkatesan T, Saeian K) South Med J 2018 Oct;111(10):628-633 PMID: 30285271 10/05/2018    
  • Meta-analysis to Evaluate High-Dose Therapy Followed by Stem Cell Transplant in Patients With Multiple Myeloma-Reply. (Dhakal B, Szabo A, Hari P) JAMA Oncol 2018 Nov 01;4(11):1618 PMID: 30098154 08/12/2018    
  • Incidence and survival of therapy related myeloid neoplasm in United States. (Guru Murthy GS, Hamadani M, Dhakal B, Hari P, Atallah E) Leuk Res 2018 Aug;71:95-99 PMID: 30048839 07/27/2018    
  • Developing a Case-Based Blended Learning Ecosystem to Optimize Precision Medicine: Reducing Overdiagnosis and Overtreatment. (Podder V, Dhakal B, Shaik GUS, Sundar K, Sivapuram MS, Chattu VK, Biswas R) Healthcare (Basel) 2018 Jul 10;6(3) PMID: 29996517 PMCID: PMC6163835 07/13/2018    
  • Repurposing existing medications as cancer therapy: design and feasibility of a randomized pilot investigating propranolol administration in patients receiving hematopoietic cell transplantation. (Knight JM, Kerswill SA, Hari P, Cole SW, Logan BR, D'Souza A, Shah NN, Horowitz MM, Stolley MR, Sloan EK, Giles KE, Costanzo ES, Hamadani M, Chhabra S, Dhakal B, Rizzo JD) BMC Cancer 2018 May 24;18(1):593 PMID: 29793446 PMCID: PMC5968588 05/26/2018    
  • Pharmacokinetics of High-Dose Propylene Glycol-Free Melphalan in Multiple Myeloma Patients Undergoing Autologous Hematopoietic Cell Transplantation. (Dhakal B, D'Souza A, Lakshman A, Hamadani M, Chhabra S, Thompson R, Shah N, Pasquini M, Hari P) Biol Blood Marrow Transplant 2018 Aug;24(8):1610-1614 PMID: 29751116 05/12/2018    
  • Disease burden, complication rates, and health-care costs of heparin-induced thrombocytopenia in the USA: a population-based study. (Dhakal B, Kreuziger LB, Rein L, Kleman A, Fraser R, Aster RH, Hari P, Padmanabhan A) Lancet Haematol 2018 May;5(5):e220-e231 PMID: 29703336 04/29/2018       3 Citations
  • Rationale and design of DUAL study: Doxycycline to Upgrade response in light chain (AL) amyloidosis (DUAL): A phase 2 pilot study of a two-pronged approach of prolonged doxycycline with plasma cell-directed therapy in the treatment of AL amyloidosis. (D'Souza A, Flynn K, Chhabra S, Dhakal B, Hamadani M, Jacobsen K, Pasquini M, Weihrauch D, Hari P) Contemp Clin Trials Commun 2017 Dec;8:33-38 PMID: 29696194 PMCID: PMC5898504 04/27/2018    
  • Peripheral Blood Grafts for T Cell-Replete Haploidentical Transplantation Increase the Incidence and Severity of Cytokine Release Syndrome. (Raj RV, Hamadani M, Szabo A, Pasquini MC, Shah NN, Drobyski WR, Shaw BE, Saber W, Rizzo JD, Jerkins J, Fenske TS, D'Souza A, Dhakal B, Zhang C, Konings S, Hari PN, Chhabra S) Biol Blood Marrow Transplant 2018 Aug;24(8):1664-1670 PMID: 29680516 04/24/2018    
  • Use of propylene glycol-free melphalan conditioning in light-chain amyloidosis patients undergoing autologous hematopoietic cell transplantation is well tolerated and effective. (Badar T, Hari P, Chhabra S, Dhakal B, Drobyski WR, Fenske TS, Hamadani M, Pasquini M, Saber W, Shah NN, Shaw BE, D'Souza A) Bone Marrow Transplant 2018 Sep;53(9):1210-1213 PMID: 29679076 04/22/2018    
  • Autologous Transplantation for Newly Diagnosed Multiple Myeloma in the Era of Novel Agent Induction: A Systematic Review and Meta-analysis. (Dhakal B, Szabo A, Chhabra S, Hamadani M, D'Souza A, Usmani SZ, Sieracki R, Gyawali B, Jackson JL, Asimakopoulos F, Hari PN) JAMA Oncol 2018 Mar 01;4(3):343-350 PMID: 29302684 PMCID: PMC5885822 01/06/2018    
  • A Platelet Factor 4-Dependent Platelet Activation Assay Facilitates Early Detection of Pathogenic Heparin-Induced Thrombocytopenia Antibodies. (Jones CG, Pechauer SM, Curtis BR, Bougie DW, Irani MS, Dhakal B, Pierce B, Aster RH, Padmanabhan A) Chest 2017 10;152(4):e77-e80 PMID: 28991552 PMCID: PMC5812761 10/11/2017       2 Citations
  • Increased Rate of Venous Thromboembolism in Hospitalized Inflammatory Bowel Disease Patients with Clostridium Difficile Infection. (Bhandari S, Mohammed Abdul MK, Dhakal B, Kreuziger LB, Saeian K, Stein D) Inflamm Bowel Dis 2017 10;23(10):1847-1852 PMID: 28837518 08/25/2017       4 Citations
  • Early mortality in patients with acute myelogenous leukemia treated in teaching versus non-teaching hospitals: A large database analysis. (Levin A, Kleman A, Rein L, Tarima S, Michaelis LC, Carlson KS, Hamadani M, Fenske TS, Hari P, Atallah E, Dhakal B) Am J Hematol 2017 Sep;92(9):E563-E565 PMID: 28631379 06/21/2017    
  • IVIg for Treatment of Severe Refractory Heparin-Induced Thrombocytopenia. (Padmanabhan A, Jones CG, Pechauer SM, Curtis BR, Bougie DW, Irani MS, Bryant BJ, Alperin JB, Deloughery TG, Mulvey KP, Dhakal B, Wen R, Wang D, Aster RH) Chest 2017 09;152(3):478-485 PMID: 28427966 PMCID: PMC5812774 04/22/2017       15 Citations
  • Marizomib for central nervous system-multiple myeloma. (Badros A, Singh Z, Dhakal B, Kwok Y, MacLaren A, Richardson P, Trikha M, Hari P) Br J Haematol 2017 04;177(2):221-225 PMID: 28387460 04/08/2017       13 Citations
  • Local Disease Control in Ocular Adnexal Lymphoproliferative Disorders: Comparative Outcomes of MALT Versus Non-MALT Histologies. (Dhakal B, Fenske TS, Ramalingam S, Shuff J, Epperla N, Hosking P, Rein L, Banerjee A, Hari P, D'Souza A, Shah N, Siker M, Griepentrog GJ, Harris GJ, Wells TS, Erickson BA, Hamadani M) Clin Lymphoma Myeloma Leuk 2017 05;17(5):305-311.e2 PMID: 28284742 03/13/2017       2 Citations
  • Autologous Hematopoietic Cell Transplantation in Patients With Multiple Myeloma: Effect of Age. (Dhakal B, Nelson A, Guru Murthy GS, Fraser R, Eastwood D, Hamadani M, Pasquini M, D'Souza A, Hari P) Clin Lymphoma Myeloma Leuk 2017 03;17(3):165-172 PMID: 28159578 02/06/2017       6 Citations
  • Reactivation of Pulmonary Tuberculosis following Treatment of Myelofibrosis with Ruxolitinib. (Abidi MZ, Haque J, Varma P, Olteanu H, Guru Murthy GS, Dhakal B, Hari P) Case Rep Hematol 2016;2016:2389038 PMID: 27843657 PMCID: PMC5097796 11/16/2016    
  • Recent advances in understanding multiple myeloma. (Dhakal B, Girnius S, Hari P) F1000Res 2016;5 PMID: 27610224 PMCID: PMC4995679 09/10/2016    
  • Hematopoietic Progenitor Cell Mobilization with Ifosfamide, Carboplatin, and Etoposide Chemotherapy versus Plerixafor-Based Strategies in Patients with Hodgkin and Non-Hodgkin Lymphoma. (Dhakal B, Veltri LW, Fenske TS, Eastwood D, Craig MD, Cumpston A, Shillingburg A, Esselman J, Watkins K, Pasquini MC, D'Souza A, Hari P, Kanate AS, Hamadani M) Biol Blood Marrow Transplant 2016 10;22(10):1773-1780 PMID: 27345140 06/28/2016       2 Citations
  • Moving Beyond Autologous Transplantation in Multiple Myeloma: Consolidation, Maintenance, Allogeneic Transplant, and Immune Therapy. (Krishnan A, Vij R, Keller J, Dhakal B, Hari P) Am Soc Clin Oncol Educ Book 2016;35:210-21 PMID: 27249701 06/02/2016       3 Citations
  • Allogeneic Hematopoietic Cell Transplantation in Multiple Myeloma: Impact of Disease Risk and Post Allograft Minimal Residual Disease on Survival. (Dhakal B, D'Souza A, Martens M, Kapke J, Harrington AM, Pasquini M, Saber W, Drobyski WR, Zhang MJ, Hamadani M, Hari PN) Clin Lymphoma Myeloma Leuk 2016 07;16(7):379-86 PMID: 27160644 05/11/2016       2 Citations
  • DAS181 Treatment of Severe Parainfluenza Virus 3 Pneumonia in Allogeneic Hematopoietic Stem Cell Transplant Recipients Requiring Mechanical Ventilation. (Dhakal B, D'Souza A, Pasquini M, Saber W, Fenske TS, Moss RB, Drobyski WR, Hari P, Abidi MZ) Case Rep Med 2016;2016:8503275 PMID: 26941799 PMCID: PMC4749780 03/05/2016    
  • Allogeneic stem cell transplantation for multiple myeloma: is there a future? (Dhakal B, Vesole DH, Hari PN) Bone Marrow Transplant 2016 Apr;51(4):492-500 PMID: 26726943 01/05/2016       23 Citations
  • Monocyte recovery at day 100 is associated with improved survival in multiple myeloma patients who undergo allogeneic hematopoietic cell transplantation. (Dhakal B, Brazauskas R, Lara CA, Hari P, Pasquini M, D'Souza A) Bone Marrow Transplant 2016 Feb;51(2):297-9 PMID: 26457907 PMCID: PMC4956087 10/13/2015    
  • Presentation and management of post-allogeneic transplantation EBV-positive mucocutaneous ulcer. (Nelson AA, Harrington AM, Kroft S, Dahar MA, Hamadani M, Dhakal B) Bone Marrow Transplant 2016 Feb;51(2):300-2 PMID: 26457913 10/13/2015       14 Citations
  • Localized lymph node light chain amyloidosis. (Dhakal B, Harrington AM, Stadler ME, D'Souza A) Case Rep Hematol 2015;2015:816565 PMID: 25922771 PMCID: PMC4398934 04/30/2015    
  • Superior efficacy but higher cost of plerixafor and abbreviated-course G-CSF for mobilizing hematopoietic progenitor cells (HPC) in AL amyloidosis. (Dhakal B, D'Souza A, Arce-Lara C, Pasquini M, Saber W, Falvo F, Esselman J, Zellner K, Fenske T, Hari PN, Hamadani M) Bone Marrow Transplant 2015 Apr;50(4):610-2 PMID: 25621807 01/27/2015       3 Citations
  • Chronic GVHD and concurrent new-onset nephrotic syndrome in allogeneic transplant recipients. Incidence, pattern and therapeutic outcomes. (Dhakal B, Singavi A, Cohen EP, Dangal M, Palmer J, Dall A, D'Souza A, Hamadani M, Hari PN) Bone Marrow Transplant 2015 Mar;50(3):449-51 PMID: 25387097 11/12/2014       3 Citations
  • Plerixafor and abbreviated-course granulocyte colony-stimulating factor for mobilizing hematopoietic progenitor cells in light chain amyloidosis. (Dhakal B, Strouse C, D'Souza A, Arce-Lara C, Esselman J, Eastwood D, Pasquini M, Saber W, Drobyski W, Rizzo JD, Hari PN, Hamadani M) Biol Blood Marrow Transplant 2014 Dec;20(12):1926-31 PMID: 25111581 08/12/2014       14 Citations
  • Death during an asthma exacerbation in an adult with sickle cell disease: an autopsy case study. (Dhakal B, Giese K, Santo-Thomas L, Field JJ) Am J Hematol 2013 Sep;88(9):824 PMID: 23720156 05/31/2013       4 Citations
  • Morbidities of lung cancer surgery in obese patients. (Dhakal B, Eastwood D, Sukumaran S, Hassler G, Tisol W, Gasparri M, Choong N, Santana-Davila R) J Thorac Cardiovasc Surg 2013 Aug;146(2):379-84 PMID: 23618391 PMCID: PMC4986510 04/27/2013       18 Citations
  • Pemetrexed induced pneumonitis. (Dhakal B, Singh V, Shrestha A, Rao A, Choong N) Clin Pract 2011 Sep 28;1(4):e106 PMID: 24765347 PMCID: PMC3981441 09/28/2011    
  • Resolving diagnostic uncertainty in initially poorly localizable fevers: a prospective study. (Biswas R, Dhakal B, Das RN, Shetty KJ) Int J Clin Pract 2004 Jan;58(1):26-8 PMID: 14994967 03/05/2004       7 Citations
  • Last update: 12/31/2018
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