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Christopher Dockendorff PhD

Christopher Dockendorff PhD

Assistant Professor, Organic and Medicinal Chemistry

Institution: Marquette University
Department: Chemistry

Member of the Cancer Center


Research Experience

  • Analgesics, Opioid
  • Anti-Inflammatory Agents, Non-Steroidal
  • Anticarcinogenic Agents
  • Anticoagulants
  • Chemistry
  • Molecular Probes
  • Potassium Channel Blockers
  • Reperfusion Injury
  • Structure-Activity Relationship
  • Thrombosis
  • Publications

  • Design and Evaluation of Heterobivalent PAR1-PAR2 Ligands as Antagonists of Calcium Mobilization. (Majewski MW, Gandhi DM, Rosas R Jr, Kodali R, Arnold LA, Dockendorff C) ACS Med Chem Lett 2019 Jan 10;10(1):121-126 PMID: 30655958 PMCID: PMC6331166 01/19/2019    
  • Characterization of Protease-Activated Receptor (PAR) ligands: Parmodulins are reversible allosteric inhibitors of PAR1-driven calcium mobilization in endothelial cells. (Gandhi DM, Majewski MW, Rosas R Jr, Kentala K, Foster TJ, Greve E, Dockendorff C) Bioorg Med Chem 2018 05 15;26(9):2514-2529 PMID: 29685684 PMCID: PMC5937995 04/25/2018       1 Citations
  • Synthetic Analogues of the Snail Toxin 6-Bromo-2-mercaptotryptamine Dimer (BrMT) Reveal That Lipid Bilayer Perturbation Does Not Underlie Its Modulation of Voltage-Gated Potassium Channels. (Dockendorff C, Gandhi DM, Kimball IH, Eum KS, Rusinova R, Ing√≥lfsson HI, Kapoor R, Peyear T, Dodge MW, Martin SF, Aldrich RW, Andersen OS, Sack JT) Biochemistry 2018 05 08;57(18):2733-2743 PMID: 29616558 PMCID: PMC6007853 04/05/2018       2 Citations
  • PAR1 agonists stimulate APC-like endothelial cytoprotection and confer resistance to thromboinflammatory injury. (De Ceunynck K, Peters CG, Jain A, Higgins SJ, Aisiku O, Fitch-Tewfik JL, Chaudhry SA, Dockendorff C, Parikh SM, Ingber DE, Flaumenhaft R) Proc Natl Acad Sci U S A 2018 01 30;115(5):E982-E991 PMID: 29343648 PMCID: PMC5798377 01/19/2018       2 Citations
  • Monitoring Replication Protein A (RPA) dynamics in homologous recombination through site-specific incorporation of non-canonical amino acids. (Pokhrel N, Origanti S, Davenport EP, Gandhi D, Kaniecki K, Mehl RA, Greene EC, Dockendorff C, Antony E) Nucleic Acids Res 2017 Sep 19;45(16):9413-9426 PMID: 28934470 PMCID: PMC5766198 09/22/2017       4 Citations
  • Cytoprotective activated protein C averts Nlrp3 inflammasome-induced ischemia-reperfusion injury via mTORC1 inhibition. (Nazir S, Gadi I, Al-Dabet MM, Elwakiel A, Kohli S, Ghosh S, Manoharan J, Ranjan S, Bock F, Braun-Dullaeus RC, Esmon CT, Huber TB, Camerer E, Dockendorff C, Griffin JH, Isermann B, Shahzad K) Blood 2017 12 14;130(24):2664-2677 PMID: 28882883 PMCID: PMC5731086 09/09/2017       13 Citations
  • Indolinyl-Thiazole Based Inhibitors of Scavenger Receptor-BI (SR-BI)-Mediated Lipid Transport. (Dockendorff C, Faloon PW, Yu M, Youngsaye W, Penman M, Nieland TJ, Nag PP, Lewis TA, Pu J, Bennion M, Negri J, Paterson C, Lam G, Dandapani S, Perez JR, Munoz B, Palmer MA, Schreiber SL, Krieger M) ACS Med Chem Lett 2015 Apr 09;6(4):375-380 PMID: 26478787 PMCID: PMC4599563 10/20/2015    
  • Discovery of bisamide-heterocycles as inhibitors of scavenger receptor BI (SR-BI)-mediated lipid uptake. (Dockendorff C, Faloon PW, Germain A, Yu M, Youngsaye W, Nag PP, Bennion M, Penman M, Nieland TJ, Dandapani S, Perez JR, Munoz B, Palmer MA, Schreiber SL, Krieger M) Bioorg Med Chem Lett 2015 Jun 15;25(12):2594-8 PMID: 25958245 PMCID: PMC4469081 05/11/2015       6 Citations
  • Benzo-fused lactams from a diversity-oriented synthesis (DOS) library as inhibitors of scavenger receptor BI (SR-BI)-mediated lipid uptake. (Dockendorff C, Faloon PW, Pu J, Yu M, Johnston S, Bennion M, Penman M, Nieland TJ, Dandapani S, Perez JR, Munoz B, Palmer MA, Schreiber SL, Krieger M) Bioorg Med Chem Lett 2015;25(10):2100-5 PMID: 25900219 PMCID: PMC4469080 04/23/2015       5 Citations
  • Parmodulins inhibit thrombus formation without inducing endothelial injury caused by vorapaxar. (Aisiku O, Peters CG, De Ceunynck K, Ghosh CC, Dilks JR, Fustolo-Gunnink SF, Huang M, Dockendorff C, Parikh SM, Flaumenhaft R) Blood 2015 Mar 19;125(12):1976-85 PMID: 25587041 PMCID: PMC4366627 01/15/2015       27 Citations
  • Last update: 01/19/2019
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