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Fred Helmstetter PhD

Fred Helmstetter PhD

Professor

Institution: University of Wisconsin - Milwaukee
Department: Psychology / Neuroscience

Member of the Neuroscience Research Center


Publications

  • Cortico-limbic connectivity changes following fear extinction and relationships with trait anxiety. (Belleau EL, Pedersen WS, Miskovich TA, Helmstetter FJ, Larson CL) Soc Cogn Affect Neurosci 2018 Oct 25;13(10):1037-1046 PMID: 30137604 PMCID: PMC6204483 08/24/2018    
  • Context memory formation requires activity-dependent protein degradation in the hippocampus. (Cullen PK, Ferrara NC, Pullins SE, Helmstetter FJ) Learn Mem 2017 11;24(11):589-596 PMID: 29038220 PMCID: PMC5647928 10/19/2017       2 Citations
  • Corrigendum: Psychopaths Show Enhanced Amygdala Activation during Fear Conditioning. (Schultz DH, Balderston NL, Baskin-Sommers AR, Larson CL, Helmstetter FJ) Front Psychol 2017;8:1457 PMID: 28845153 PMCID: PMC5572079 08/29/2017    
  • Input from the medial geniculate nucleus modulates amygdala encoding of fear memory discrimination. (Ferrara NC, Cullen PK, Pullins SP, Rotondo EK, Helmstetter FJ) Learn Mem 2017 09;24(9):414-421 PMID: 28814467 PMCID: PMC5580525 08/18/2017       3 Citations
  • Updating Procedures Can Reorganize the Neural Circuit Supporting a Fear Memory. (Kwapis JL, Jarome TJ, Ferrara NC, Helmstetter FJ) Neuropsychopharmacology 2017 Jul;42(8):1688-1697 PMID: 28139682 PMCID: PMC5518901 02/01/2017       5 Citations
  • Fluorescence laminar optical tomography for brain imaging: system implementation and performance evaluation. (Azimipour M, Sheikhzadeh M, Baumgartner R, Cullen PK, Helmstetter FJ, Chang WJ, Pashaie R) J Biomed Opt 2017 01 01;22(1):16003 PMID: 28056143 PMCID: PMC5997009 01/06/2017       3 Citations
  • The effects of stimulus novelty and negativity on BOLD activity in the amygdala, hippocampus, and bed nucleus of the stria terminalis. (Pedersen WS, Balderston NL, Miskovich TA, Belleau EL, Helmstetter FJ, Larson CL) Soc Cogn Affect Neurosci 2017 05 01;12(5):748-757 PMID: 28008079 PMCID: PMC5460050 12/23/2016       5 Citations
  • Hippocampal interactions with brain networks that influence learning & memory. (Hannula DE, Helmstetter FJ) Neurobiol Learn Mem 2016 10;134 Pt A:1-4 PMID: 27565289 08/28/2016       1 Citations
  • Eye movements are captured by a perceptually simple conditioned stimulus in the absence of explicit contingency knowledge. (Hopkins LS, Helmstetter FJ, Hannula DE) Emotion 2016 12;16(8):1157-1171 PMID: 27348496 06/28/2016       3 Citations
  • Psychopaths Show Enhanced Amygdala Activation during Fear Conditioning. (Schultz DH, Balderston NL, Baskin-Sommers AR, Larson CL, Helmstetter FJ) Front Psychol 2016;7:348 PMID: 27014154 PMCID: PMC4785144 03/26/2016    
  • CaMKII regulates proteasome phosphorylation and activity and promotes memory destabilization following retrieval. (Jarome TJ, Ferrara NC, Kwapis JL, Helmstetter FJ) Neurobiol Learn Mem 2016 Feb;128:103-9 PMID: 26779588 PMCID: PMC4754128 01/19/2016       31 Citations
  • Eye Movements Index Implicit Memory Expression in Fear Conditioning. (Hopkins LS, Schultz DH, Hannula DE, Helmstetter FJ) PLoS One 2015;10(11):e0141949 PMID: 26562298 PMCID: PMC4642991 11/13/2015       2 Citations
  • The retrosplenial cortex is involved in the formation of memory for context and trace fear conditioning. (Kwapis JL, Jarome TJ, Lee JL, Helmstetter FJ) Neurobiol Learn Mem 2015 Sep;123:110-6 PMID: 26079095 PMCID: PMC4754129 06/17/2015       24 Citations
  • Contextual Information Drives the Reconsolidation-Dependent Updating of Retrieved Fear Memories. (Jarome TJ, Ferrara NC, Kwapis JL, Helmstetter FJ) Neuropsychopharmacology 2015 Dec;40(13):3044-52 PMID: 26062788 PMCID: PMC4864640 06/13/2015       8 Citations
  • Functionally distinct amygdala subregions identified using DTI and high-resolution fMRI. (Balderston NL, Schultz DH, Hopkins L, Helmstetter FJ) Soc Cogn Affect Neurosci 2015 Dec;10(12):1615-22 PMID: 25969533 PMCID: PMC4666105 05/15/2015       9 Citations
  • The role of the medial prefrontal cortex in trace fear extinction. (Kwapis JL, Jarome TJ, Helmstetter FJ) Learn Mem 2014 Jan;22(1):39-46 PMID: 25512576 PMCID: PMC4274329 12/17/2014       10 Citations
  • Protein degradation and protein synthesis in long-term memory formation. (Jarome TJ, Helmstetter FJ) Front Mol Neurosci 2014;7:61 PMID: 25018696 PMCID: PMC4072070 07/16/2014    
  • Prefrontal cortical regulation of fear learning. (Gilmartin MR, Balderston NL, Helmstetter FJ) Trends Neurosci 2014 Aug;37(8):455-64 PMID: 24929864 PMCID: PMC4119830 06/16/2014       61 Citations
  • Rapid amygdala responses during trace fear conditioning without awareness. (Balderston NL, Schultz DH, Baillet S, Helmstetter FJ) PLoS One 2014;9(5):e96803 PMID: 24823365 PMCID: PMC4019542 05/16/2014       11 Citations
  • The ubiquitin-specific protease 14 (USP14) is a critical regulator of long-term memory formation. (Jarome TJ, Kwapis JL, Hallengren JJ, Wilson SM, Helmstetter FJ) Learn Mem 2013 Dec 16;21(1):9-13 PMID: 24344179 PMCID: PMC3867711 12/18/2013       20 Citations
  • Memory formation for trace fear conditioning requires ubiquitin-proteasome mediated protein degradation in the prefrontal cortex. (Reis DS, Jarome TJ, Helmstetter FJ) Front Behav Neurosci 2013;7:150 PMID: 24167477 PMCID: PMC3805936 10/30/2013    
  • Does PKM(zeta) maintain memory? (Kwapis JL, Helmstetter FJ) Brain Res Bull 2014 Jun;105:36-45 PMID: 24076105 PMCID: PMC3966985 10/01/2013       34 Citations
  • Extinguishing trace fear engages the retrosplenial cortex rather than the amygdala. (Kwapis JL, Jarome TJ, Lee JL, Gilmartin MR, Helmstetter FJ) Neurobiol Learn Mem 2014 Sep;113:41-54 PMID: 24055593 PMCID: PMC3959632 09/24/2013       21 Citations
  • CaMKII, but not protein kinase A, regulates Rpt6 phosphorylation and proteasome activity during the formation of long-term memories. (Jarome TJ, Kwapis JL, Ruenzel WL, Helmstetter FJ) Front Behav Neurosci 2013;7:115 PMID: 24009566 PMCID: PMC3757295 09/07/2013    
  • Prefrontal activity links nonoverlapping events in memory. (Gilmartin MR, Miyawaki H, Helmstetter FJ, Diba K) J Neurosci 2013 Jun 26;33(26):10910-4 PMID: 23804110 PMCID: PMC3693060 06/28/2013       35 Citations
  • How to detect amygdala activity with magnetoencephalography using source imaging. (Balderston NL, Schultz DH, Baillet S, Helmstetter FJ) J Vis Exp 2013 Jun 03(76) PMID: 23770774 PMCID: PMC3726041 06/19/2013       1 Citations
  • Dissociation between implicit and explicit responses in postconditioning UCS revaluation after fear conditioning in humans. (Schultz DH, Balderston NL, Geiger JA, Helmstetter FJ) Behav Neurosci 2013 Jun;127(3):357-68 PMID: 23731073 PMCID: PMC3959889 06/05/2013       14 Citations
  • NR2A- and NR2B-containing NMDA receptors in the prelimbic medial prefrontal cortex differentially mediate trace, delay, and contextual fear conditioning. (Gilmartin MR, Kwapis JL, Helmstetter FJ) Learn Mem 2013 May 15;20(6):290-4 PMID: 23676200 PMCID: PMC3677083 05/17/2013       35 Citations
  • The effect of threat on novelty evoked amygdala responses. (Balderston NL, Schultz DH, Helmstetter FJ) PLoS One 2013;8(5):e63220 PMID: 23658813 PMCID: PMC3643910 05/10/2013       11 Citations
  • Memory accuracy predicts hippocampal mTOR pathway activation following retrieval of contextual fear memory. (Gafford GM, Parsons RG, Helmstetter FJ) Hippocampus 2013 Sep;23(9):842-7 PMID: 23640842 PMCID: PMC3775923 05/04/2013       14 Citations
  • The ubiquitin-proteasome system as a critical regulator of synaptic plasticity and long-term memory formation. (Jarome TJ, Helmstetter FJ) Neurobiol Learn Mem 2013 Oct;105:107-16 PMID: 23623827 PMCID: PMC3786694 04/30/2013       55 Citations
  • Resting-state connectivity of the amygdala is altered following Pavlovian fear conditioning. (Schultz DH, Balderston NL, Helmstetter FJ) Front Hum Neurosci 2012;6:242 PMID: 22936906 PMCID: PMC3426015 09/01/2012    
  • The timing of multiple retrieval events can alter GluR1 phosphorylation and the requirement for protein synthesis in fear memory reconsolidation. (Jarome TJ, Kwapis JL, Werner CT, Parsons RG, Gafford GM, Helmstetter FJ) Learn Mem 2012 Jun 20;19(7):300-6 PMID: 22723052 PMCID: PMC3381327 06/23/2012       27 Citations
  • Intra-amygdala infusion of the protein kinase Mzeta inhibitor ZIP disrupts foreground context fear memory. (Kwapis JL, Jarome TJ, Gilmartin MR, Helmstetter FJ) Neurobiol Learn Mem 2012 Sep;98(2):148-53 PMID: 22659643 PMCID: PMC3424353 06/05/2012       22 Citations
  • Trace and contextual fear conditioning are impaired following unilateral microinjection of muscimol in the ventral hippocampus or amygdala, but not the medial prefrontal cortex. (Gilmartin MR, Kwapis JL, Helmstetter FJ) Neurobiol Learn Mem 2012 May;97(4):452-64 PMID: 22469748 PMCID: PMC3358523 04/04/2012       44 Citations
  • Memory consolidation in both trace and delay fear conditioning is disrupted by intra-amygdala infusion of the protein synthesis inhibitor anisomycin. (Kwapis JL, Jarome TJ, Schiff JC, Helmstetter FJ) Learn Mem 2011 Nov;18(11):728-32 PMID: 22028394 PMCID: PMC3207254 10/27/2011       35 Citations
  • Activity dependent protein degradation is critical for the formation and stability of fear memory in the amygdala. (Jarome TJ, Werner CT, Kwapis JL, Helmstetter FJ) PLoS One 2011;6(9):e24349 PMID: 21961035 PMCID: PMC3178530 10/01/2011       81 Citations
  • Consolidation and reconsolidation of contextual fear memory requires mammalian target of rapamycin-dependent translation in the dorsal hippocampus. (Gafford GM, Parsons RG, Helmstetter FJ) Neuroscience 2011 May 19;182:98-104 PMID: 21439355 PMCID: PMC3087706 03/29/2011       68 Citations
  • The human amygdala plays a stimulus specific role in the detection of novelty. (Balderston NL, Schultz DH, Helmstetter FJ) Neuroimage 2011 Apr 15;55(4):1889-98 PMID: 21256226 PMCID: PMC3062695 01/25/2011       46 Citations
  • Classical conditioning of autonomic fear responses is independent of contingency awareness. (Schultz DH, Helmstetter FJ) J Exp Psychol Anim Behav Process 2010 Oct;36(4):495-500 PMID: 20973611 10/27/2010       46 Citations
  • Regulation of extinction-related plasticity by opioid receptors in the ventrolateral periaqueductal gray matter. (Parsons RG, Gafford GM, Helmstetter FJ) Front Behav Neurosci 2010;4 PMID: 20740074 PMCID: PMC2927240 08/27/2010    
  • Conditioning with masked stimuli affects the timecourse of skin conductance responses. (Balderston NL, Helmstetter FJ) Behav Neurosci 2010 Aug;124(4):478-89 PMID: 20695647 PMCID: PMC5275764 08/11/2010       18 Citations
  • Time-dependent expression of Arc and zif268 after acquisition of fear conditioning. (Lonergan ME, Gafford GM, Jarome TJ, Helmstetter FJ) Neural Plast 2010;2010:139891 PMID: 20592749 PMCID: PMC2877205 07/02/2010       60 Citations
  • Trace and contextual fear conditioning require neural activity and NMDA receptor-dependent transmission in the medial prefrontal cortex. (Gilmartin MR, Helmstetter FJ) Learn Mem 2010 Jun;17(6):289-96 PMID: 20504949 PMCID: PMC2884289 05/28/2010       81 Citations
  • Chronic stress selectively reduces hippocampal volume in rats: a longitudinal magnetic resonance imaging study. (Lee T, Jarome T, Li SJ, Kim JJ, Helmstetter FJ) Neuroreport 2009 Nov 25;20(17):1554-8 PMID: 19858767 PMCID: PMC2783199 10/28/2009       69 Citations
  • Introgression of Brown Norway chromosome 1 onto the fawn hooded hypertensive background rescues long-term fear memory deficits. (Jarome TJ, Kwapis JL, Nye SH, Helmstetter FJ) Behav Genet 2010 Jan;40(1):85-92 PMID: 19757016 PMCID: PMC5275762 09/17/2009       5 Citations
  • Protein kinase Mzeta maintains fear memory in the amygdala but not in the hippocampus. (Kwapis JL, Jarome TJ, Lonergan ME, Helmstetter FJ) Behav Neurosci 2009 Aug;123(4):844-50 PMID: 19634944 PMCID: PMC2782955 07/29/2009       56 Citations
  • An updated unified pharmacophore model of the benzodiazepine binding site on gamma-aminobutyric acid(a) receptors: correlation with comparative models. (Clayton T, Chen JL, Ernst M, Richter L, Cromer BA, Morton CJ, Ng H, Kaczorowski CC, Helmstetter FJ, Furtmüller R, Ecker G, Parker MW, Sieghart W, Cook JM) Curr Med Chem 2007;14(26):2755-75 PMID: 18045122 11/30/2007       46 Citations
  • Macromolecular synthesis, distributed synaptic plasticity, and fear conditioning. (Helmstetter FJ, Parsons RG, Gafford GM) Neurobiol Learn Mem 2008 Mar;89(3):324-37 PMID: 17977027 PMCID: PMC2297466 11/03/2007       56 Citations
  • Activity in the human amygdala corresponds to early, rather than late period autonomic responses to a signal for shock. (Cheng DT, Richards J, Helmstetter FJ) Learn Mem 2007 Jul;14(7):485-90 PMID: 17626906 PMCID: PMC1934343 07/14/2007       51 Citations
  • Human amygdala activity during the expression of fear responses. (Cheng DT, Knight DC, Smith CN, Helmstetter FJ) Behav Neurosci 2006 Dec;120(6):1187-95 PMID: 17201461 01/05/2007       78 Citations
  • Translational control via the mammalian target of rapamycin pathway is critical for the formation and stability of long-term fear memory in amygdala neurons. (Parsons RG, Gafford GM, Helmstetter FJ) J Neurosci 2006 Dec 13;26(50):12977-83 PMID: 17167087 12/15/2006       174 Citations
  • The formation of auditory fear memory requires the synthesis of protein and mRNA in the auditory thalamus. (Parsons RG, Riedner BA, Gafford GM, Helmstetter FJ) Neuroscience 2006 Sep 01;141(3):1163-70 PMID: 16766126 PMCID: PMC1698266 06/13/2006       27 Citations
  • Long-term stability of fear memory depends on the synthesis of protein but not mRNA in the amygdala. (Parsons RG, Gafford GM, Baruch DE, Riedner BA, Helmstetter FJ) Eur J Neurosci 2006 Apr;23(7):1853-9 PMID: 16623842 PMCID: PMC1698267 04/21/2006       68 Citations
  • Effects of post-training hippocampal injections of midazolam on fear conditioning. (Gafford GM, Parsons RG, Helmstetter FJ) Learn Mem 2005 Nov-Dec;12(6):573-8 PMID: 16322359 PMCID: PMC1356174 12/03/2005       15 Citations
  • Antinociception following application of DAMGO to the basolateral amygdala results from a direct interaction of DAMGO with Mu opioid receptors in the amygdala. (Shin MS, Helmstetter FJ) Brain Res 2005 Dec 07;1064(1-2):56-65 PMID: 16289487 11/18/2005       16 Citations
  • Amygdala and hippocampal activity during acquisition and extinction of human fear conditioning. (Knight DC, Smith CN, Cheng DT, Stein EA, Helmstetter FJ) Cogn Affect Behav Neurosci 2004 Sep;4(3):317-25 PMID: 15535167 11/13/2004       157 Citations
  • Effects of exercise on Pavlovian fear conditioning. (Baruch DE, Swain RA, Helmstetter FJ) Behav Neurosci 2004 Oct;118(5):1123-7 PMID: 15506895 10/28/2004       56 Citations
  • Neural substrates mediating human delay and trace fear conditioning. (Knight DC, Cheng DT, Smith CN, Stein EA, Helmstetter FJ) J Neurosci 2004 Jan 07;24(1):218-28 PMID: 14715954 01/13/2004       174 Citations
  • Functional MRI of human amygdala activity during Pavlovian fear conditioning: stimulus processing versus response expression. (Cheng DT, Knight DC, Smith CN, Stein EA, Helmstetter FJ) Behav Neurosci 2003 Feb;117(1):3-10 PMID: 12619902 03/07/2003       105 Citations
  • Effects of hippocampal injections of a novel ligand selective for the alpha 5 beta 2 gamma 2 subunits of the GABA/benzodiazepine receptor on Pavlovian conditioning. (Bailey DJ, Tetzlaff JE, Cook JM, He X, Helmstetter FJ) Neurobiol Learn Mem 2002 Jul;78(1):1-10 PMID: 12071663 06/20/2002       39 Citations
  • Calcitonin gene-related peptide released within the amygdala is involved in Pavlovian auditory fear conditioning. (Kocorowski LH, Helmstetter FJ) Neurobiol Learn Mem 2001 Mar;75(2):149-63 PMID: 11222057 02/27/2001    
  • Activation of kappa opioid receptors in the rostral ventromedial medulla blocks stress-induced antinociception. (Foo H, Helmstetter FJ) Neuroreport 2000 Oct 20;11(15):3349-52 PMID: 11059900 11/04/2000       7 Citations
  • Antinociception produced by mu opioid receptor activation in the amygdala is partly dependent on activation of mu opioid and neurotensin receptors in the ventral periaqueductal gray. (Tershner SA, Helmstetter FJ) Brain Res 2000 May 19;865(1):17-26 PMID: 10814729 05/18/2000       66 Citations
  • Expression of antinociception in response to a signal for shock is blocked after selective downregulation of mu-opioid receptors in the rostral ventromedial medulla. (Foo H, Helmstetter FJ) Brain Res Mol Brain Res 2000 Mar 29;76(2):282-8 PMID: 10762703 04/14/2000       11 Citations
  • Functional MRI of human Pavlovian fear conditioning: patterns of activation as a function of learning. (Knight DC, Smith CN, Stein EA, Helmstetter FJ) Neuroreport 1999 Nov 26;10(17):3665-70 PMID: 10619663 01/05/2000       68 Citations
  • Hypoalgesia elicited by a conditioned stimulus is blocked by a mu, but not a delta or a kappa, opioid antagonist injected into the rostral ventromedial medulla. (Foo H, Helmstetter FJ) Pain 1999 Dec;83(3):427-31 PMID: 10568850 11/24/1999       24 Citations
  • Acquisition of fear conditioning in rats requires the synthesis of mRNA in the amygdala. (Bailey DJ, Kim JJ, Sun W, Thompson RF, Helmstetter FJ) Behav Neurosci 1999 Apr;113(2):276-82 PMID: 10357452 06/05/1999       126 Citations
  • The role of mu and kappa opioid receptors within the periaqueductal gray in the expression of conditional hypoalgesia. (Bellgowan PS, Helmstetter FJ) Brain Res 1998 Apr 27;791(1-2):83-9 PMID: 9593835 06/19/1998       37 Citations
  • Antinociception following opioid stimulation of the basolateral amygdala is expressed through the periaqueductal gray and rostral ventromedial medulla. (Helmstetter FJ, Tershner SA, Poore LH, Bellgowan PS) Brain Res 1998 Jan 01;779(1-2):104-18 PMID: 9473612 02/25/1998       108 Citations
  • The effects of central injections of calcitonin gene-related peptide on fear-related behavior. (Poore LH, Helmstetter FJ) Neurobiol Learn Mem 1996 Sep;66(2):241-5 PMID: 8946417 09/01/1996       25 Citations
  • Neural systems for the expression of hypoalgesia during nonassociative fear. (Bellgowan PS, Helmstetter FJ) Behav Neurosci 1996 Aug;110(4):727-36 PMID: 8864264 08/01/1996       59 Citations
  • Microinfusion of mu but not delta or kappa opioid agonists into the basolateral amygdala results in inhibition of the tail flick reflex in pentobarbital-anesthetized rats. (Helmstetter FJ, Bellgowan PS, Poore LH) J Pharmacol Exp Ther 1995 Oct;275(1):381-8 PMID: 7562575 10/01/1995       52 Citations
  • Lesions of the periaqueductal gray and rostral ventromedial medulla disrupt antinociceptive but not cardiovascular aversive conditional responses. (Helmstetter FJ, Tershner SA) J Neurosci 1994 Nov;14(11 Pt 2):7099-108 PMID: 7965101 11/01/1994       71 Citations
  • Effects of muscimol applied to the basolateral amygdala on acquisition and expression of contextual fear conditioning in rats. (Helmstetter FJ, Bellgowan PS) Behav Neurosci 1994 Oct;108(5):1005-9 PMID: 7826507 10/01/1994       184 Citations
  • Hypoalgesia in response to sensitization during acute noise stress. (Helmstetter FJ, Bellgowan PS) Behav Neurosci 1994 Feb;108(1):177-85 PMID: 8192843 02/01/1994       26 Citations
  • Functional mapping of the rat brain during drinking behavior: a fluorodeoxyglucose study. (Gonzalez-Lima F, Helmstetter FJ, Agudo J) Physiol Behav 1993 Sep;54(3):605-12 PMID: 8415957 09/01/1993       48 Citations
  • Lesions of the amygdala block conditional hypoalgesia on the tail flick test. (Helmstetter FJ, Bellgowan PS) Brain Res 1993 May 28;612(1-2):253-7 PMID: 8330203 05/28/1993       106 Citations
  • Inhibition of the tail flick reflex following microinjection of morphine into the amygdala. (Helmstetter FJ, Bellgowan PS, Tershner SA) Neuroreport 1993 May;4(5):471-4 PMID: 8513121 05/01/1993       60 Citations
  • Stress-induced hypoalgesia and defensive freezing are attenuated by application of diazepam to the amygdala. (Helmstetter FJ) Pharmacol Biochem Behav 1993 Feb;44(2):433-8 PMID: 8446677 02/01/1993       79 Citations
  • Contribution of the amygdala to learning and performance of conditional fear. (Helmstetter FJ) Physiol Behav 1992 Jun;51(6):1271-6 PMID: 1641430 06/01/1992       83 Citations
  • The amygdala is essential for the expression of conditional hypoalgesia. (Helmstetter FJ) Behav Neurosci 1992 Jun;106(3):518-28 PMID: 1319714 06/01/1992       161 Citations
  • Differential effects of selective opioid peptide antagonists on the acquisition of pavlovian fear conditioning. (Fanselow MS, Kim JJ, Young SL, Calcagnetti DJ, DeCola JP, Helmstetter FJ, Landeira-Fernandez J) Peptides 1991 Sep-Oct;12(5):1033-7 PMID: 1686930 09/01/1991       36 Citations
  • Effects of systemic and intra-amygdaloid diazepam on long-term habituation of acoustic startle in rats. (Young BJ, Helmstetter FJ, Rabchenuk SA, Leaton RN) Pharmacol Biochem Behav 1991 Aug;39(4):903-9 PMID: 1763110 08/01/1991       22 Citations
  • Conditional hypoalgesia is attenuated by naltrexone applied to the periaqueductal gray. (Helmstetter FJ, Landeira-Fernandez J) Brain Res 1990 Dec 24;537(1-2):88-92 PMID: 1964843 12/24/1990       68 Citations
  • Role of mu and kappa opioid receptors in conditional fear-induced analgesia: the antagonistic actions of nor-binaltorphimine and the cyclic somatostatin octapeptide, Cys2Tyr3Orn5Pen7-amide. (Fanselow MS, Calcagnetti DJ, Helmstetter FJ) J Pharmacol Exp Ther 1989 Sep;250(3):825-30 PMID: 2570868 09/01/1989       54 Citations
  • Modulation of appetitively and aversively motivated behavior by the kappa opioid antagonist MR2266. (Fanselow MS, Calcagnetti DJ, Helmstetter FJ) Behav Neurosci 1989 Jun;103(3):663-72 PMID: 2544207 06/01/1989       18 Citations
  • [D-Ala2,Leu5,Cys6]enkephalin: short-term agonist effects and long-term antagonism at delta opioid receptors. (Calcagnetti DJ, Fanselow MS, Helmstetter FJ, Bowen WD) Peptides 1989 Mar-Apr;10(2):319-26 PMID: 2547203 03/01/1989       25 Citations
  • Delta opioid antagonist, 16-Me cyprenorphine, selectively attenuates conditional fear- and DPDPE-induced analgesia on the formalin test. (Fanselow MS, Calcagnetti DJ, Helmstetter FJ) Pharmacol Biochem Behav 1989 Feb;32(2):469-73 PMID: 2542994 02/01/1989       25 Citations
  • Changes in feeding and foraging patterns as an antipredator defensive strategy: a laboratory simulation using aversive stimulation in a closed economy. (Fanselow MS, Lester LS, Helmstetter FJ) J Exp Anal Behav 1988 Nov;50(3):361-74 PMID: 3209954 PMCID: PMC1338904 11/01/1988       45 Citations
  • Analgesia produced by centrally administered DAGO, DPDPE and U50488H in the formalin test. (Calcagnetti DJ, Helmstetter FJ, Fanselow MS) Eur J Pharmacol 1988 Aug 09;153(1):117-22 PMID: 3215276 08/09/1988       38 Citations
  • Ethylketocyclazocine and bremazocine analgesia in neonatal rats. (Helmstetter FJ, Calcagnetti DJ, Cramer CP, Fanselow MS) Pharmacol Biochem Behav 1988 Aug;30(4):817-21 PMID: 3067243 08/01/1988       12 Citations
  • Conditional analgesia, defensive freezing, and benzodiazepines. (Fanselow MS, Helmstetter FJ) Behav Neurosci 1988 Apr;102(2):233-43 PMID: 3365319 04/01/1988       185 Citations
  • Peripheral versus intracerebroventricular administration of quaternary naltrexone and the enhancement of Pavlovian conditioning. (Fanselow MS, Calcagnetti DJ, Helmstetter FJ) Brain Res 1988 Mar 15;444(1):147-52 PMID: 3359284 03/15/1988       26 Citations
  • Strain differences in reversal of conditional analgesia by opioid antagonists. (Helmstetter FJ, Fanselow MS) Behav Neurosci 1987 Oct;101(5):735-7 PMID: 3675853 10/01/1987       25 Citations
  • Quaternary naltrexone reveals the central mediation of conditional opioid analgesia. (Calcagnetti DJ, Helmstetter FJ, Fanselow MS) Pharmacol Biochem Behav 1987 Jul;27(3):529-31 PMID: 2821555 07/01/1987       35 Citations
  • Central and peripheral injection of quaternary antagonist, SR58002C, reduces drinking. (Calcagnetti DJ, Helmstetter FJ, Fanselow MS) Physiol Behav 1987;40(5):573-5 PMID: 3671520 01/01/1987       5 Citations
  • Effects of naltrexone on learning and performance of conditional fear-induced freezing and opioid analgesia. (Helmstetter FJ, Fanselow MS) Physiol Behav 1987;39(4):501-5 PMID: 3575497 01/01/1987       65 Citations
  • Last update: 12/26/2018
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