Medical College of Wisconsin
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Jack Gorski MD, PhD

Assistant Professor

Institution: Medical College of Wisconsin
Department: Microbiology and Immunology


Publications (27)

  • Surveillance Study of Influenza Occurrence and Immunity in a Wisconsin Cohort During the 2009 Pandemic. (Lo CY, Strobl SL, Dunham K, Wang W, Stewart L, Misplon JA, Garcia M, Gao J, Ozawa T, Price GE, Navidad J, Gradus S, Bhattacharyya S, Viboud C, Eichelberger MC, Weiss CD, Gorski J, Epstein SL) Open Forum Infect Dis 2017;4(2):ofx023 PMID: 28730155 PMCID: PMC5510460 07/22/2017    
  • Structural and Mechanistic Implications of Rearrangement Frequencies within Human TCRBV Genes. (Yassai MB, Demos W, Gorski J) J Immunol 2017 08 01;199(3):1142-1152 PMID: 28659354 PMCID: PMC5659713 SCOPUS ID: 2-s2.0-85026198299 07/01/2017    
  • CDR3 motif generation and selection in the BV19-utilizing subset of the human CD8 T cell repertoire. (Yassai MB, Demos W, Gorski J) Mol Immunol 2016 Apr;72:57-64 PMID: 26963408 PMCID: PMC5045866 SCOPUS ID: 2-s2.0-84959490724 03/11/2016       2 Citations
  • CDR3 clonotype and amino acid motif diversity of BV19 expressing circulating human CD8 T cells. (Yassai MB, Demos W, Janczak T, Naumova EN, Gorski J) Hum Immunol 2016 Jan;77(1):137-145 PMID: 26593155 PMCID: PMC4896086 SCOPUS ID: 2-s2.0-84969375503 11/26/2015       2 Citations
  • The functional CD8 T cell memory recall repertoire responding to the influenza A M1(58-66) epitope is polyclonal and shows a complex clonotype distribution. (Zhou V, Yassai MB, Regunathan J, Box J, Bosenko D, Vashishath Y, Demos W, Lee F, Gorski J) Hum Immunol 2013 Jul;74(7):809-17 PMID: 23295548 PMCID: PMC3665722 SCOPUS ID: 2-s2.0-84878599971 01/09/2013       3 Citations
  • Cross-reactivity of T cells and its role in the immune system. (Petrova G, Ferrante A, Gorski J) Crit Rev Immunol 2012;32(4):349-72 PMID: 23237510 PMCID: PMC3595599 SCOPUS ID: 2-s2.0-84871332199 12/15/2012       27 Citations
  • Transcriptional signatures as a disease-specific and predictive inflammatory biomarker for type 1 diabetes. (Levy H, Wang X, Kaldunski M, Jia S, Kramer J, Pavletich SJ, Reske M, Gessel T, Yassai M, Quasney MW, Dahmer MK, Gorski J, Hessner MJ) Genes Immun 2012 Dec;13(8):593-604 PMID: 22972474 PMCID: PMC4265236 SCOPUS ID: 2-s2.0-84870911405 09/14/2012       42 Citations
  • Deviations in influenza seasonality: odd coincidence or obscure consequence? (Moorthy M, Castronovo D, Abraham A, Bhattacharyya S, Gradus S, Gorski J, Naumov YN, Fefferman NH, Naumova EN) Clin Microbiol Infect 2012 Oct;18(10):955-62 PMID: 22958213 PMCID: PMC3442949 SCOPUS ID: 2-s2.0-84866175588 09/11/2012       10 Citations
  • The TCR repertoires of regulatory and conventional T cells specific for the same foreign antigen are distinct. (Relland LM, Williams JB, Relland GN, Haribhai D, Ziegelbauer J, Yassai M, Gorski J, Williams CB) J Immunol 2012 Oct 01;189(7):3566-74 PMID: 22933635 PMCID: PMC3538134 SCOPUS ID: 2-s2.0-84866532545 08/31/2012       17 Citations
  • Developmental dynamics of post-selection thymic DN iNKT. (Yassai M, Cooley B, Gorski J) PLoS One 2012;7(8):e43509 PMID: 22927977 PMCID: PMC3425480 SCOPUS ID: 2-s2.0-84865161299 08/29/2012       2 Citations
  • Cross-reactive responses to modified M1₅₈-₆₆ peptides by CD8⁺ T cells that use noncanonical BV genes can describe unknown repertoires. (Petrova GV, Gorski J) Eur J Immunol 2012 Nov;42(11):3001-8 PMID: 22865108 PMCID: PMC3817827 SCOPUS ID: 2-s2.0-84868128246 08/07/2012       5 Citations
  • A Peptide/MHCII conformer generated in the presence of exchange peptide is substrate for HLA-DM editing. (Ferrante A, Gorski J) Sci Rep 2012;2:386 PMID: 22545194 PMCID: PMC3338121 05/01/2012    
  • Emergence of T cells that recognize nonpolymorphic antigens during graft-versus- host disease. (Rangarajan H, Yassai M, Subramanian H, Komorowski R, Whitaker M, Gorski J, Drobyski WR) Blood 2012 Jun 28;119(26):6354-64 PMID: 22496151 PMCID: PMC3383195 SCOPUS ID: 2-s2.0-84863508785 04/13/2012       19 Citations
  • Enthalpy-entropy compensation and cooperativity as thermodynamic epiphenomena of structural flexibility in ligand-receptor interactions. (Ferrante A, Gorski J) J Mol Biol 2012 Apr 13;417(5):454-67 PMID: 22342886 PMCID: PMC3349339 SCOPUS ID: 2-s2.0-84858277308 02/22/2012       36 Citations
  • High-throughput detection method for influenza virus. (Kumar P, Bartoszek AE, Moran TM, Gorski J, Bhattacharyya S, Navidad JF, Thakar MS, Malarkannan S) J Vis Exp 2012 Feb 04(60) PMID: 22331038 PMCID: PMC3369630 SCOPUS ID: 2-s2.0-84856989933 02/15/2012       9 Citations
  • A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversity. (Haribhai D, Williams JB, Jia S, Nickerson D, Schmitt EG, Edwards B, Ziegelbauer J, Yassai M, Li SH, Relland LM, Wise PM, Chen A, Zheng YQ, Simpson PM, Gorski J, Salzman NH, Hessner MJ, Chatila TA, Williams CB) Immunity 2011 Jul 22;35(1):109-22 PMID: 21723159 PMCID: PMC3295638 SCOPUS ID: 2-s2.0-79960453738 07/05/2011       290 Citations
  • The polyclonal CD8 T cell response to influenza M158-66 generates a fully connected network of cross-reactive clonotypes to structurally related peptides: a paradigm for memory repertoire coverage of novel epitopes or escape mutants. (Petrova GV, Naumova EN, Gorski J) J Immunol 2011 Jun 01;186(11):6390-7 PMID: 21518969 PMCID: PMC4513670 SCOPUS ID: 2-s2.0-79958020932 04/27/2011       8 Citations
  • Selective T cell expansion during aging of CD8 memory repertoires to influenza revealed by modeling. (Naumov YN, Naumova EN, Yassai MB, Gorski J) J Immunol 2011 Jun 01;186(11):6617-24 PMID: 21515795 SCOPUS ID: 2-s2.0-79958026137 04/26/2011       10 Citations
  • Naive T cell repertoire skewing in HLA-A2 individuals by a specialized rearrangement mechanism results in public memory clonotypes. (Yassai M, Bosenko D, Unruh M, Zacharias G, Reed E, Demos W, Ferrante A, Gorski J) J Immunol 2011 Mar 01;186(5):2970-7 PMID: 21282510 SCOPUS ID: 2-s2.0-79952744302 02/02/2011       10 Citations
  • Functional dichotomy between NKG2D and CD28-mediated co-stimulation in human CD8+ T cells. (Rajasekaran K, Xiong V, Fong L, Gorski J, Malarkannan S) PLoS One 2010 Sep 09;5(9) PMID: 20844584 PMCID: PMC2936560 SCOPUS ID: 2-s2.0-77958581426 09/17/2010       31 Citations
  • Disproportional effects in populations of concern for pandemic influenza: insights from seasonal epidemics in Wisconsin, 1967-2004. (Lofgren ET, Wenger JB, Fefferman NH, Bina D, Gradus S, Bhattacharyya S, Naumov YN, Gorski J, Naumova EN) Influenza Other Respir Viruses 2010 Jul;4(4):205-12 PMID: 20836795 PMCID: PMC2951388 SCOPUS ID: 2-s2.0-77954503866 09/15/2010       5 Citations
  • Cutting edge: HLA-DM-mediated peptide exchange functions normally on MHC class II-peptide complexes that have been weakened by elimination of a conserved hydrogen bond. (Ferrante A, Gorski J) J Immunol 2010 Feb 01;184(3):1153-8 PMID: 20038641 SCOPUS ID: 2-s2.0-77949315137 12/30/2009       26 Citations
  • Peptide-MHC class II complex stability governs CD4 T cell clonal selection. (Baumgartner CK, Ferrante A, Nagaoka M, Gorski J, Malherbe LP) J Immunol 2010 Jan 15;184(2):573-81 PMID: 20007533 PMCID: PMC2975033 SCOPUS ID: 2-s2.0-76249124400 12/17/2009       24 Citations
  • Two compensatory pathways maintain long-term stability and diversity in CD8 T cell memory repertoires. (Naumova EN, Gorski J, Naumov YN) J Immunol 2009 Aug 15;183(4):2851-8 PMID: 19635925 SCOPUS ID: 2-s2.0-70149120774 07/29/2009       16 Citations
  • The transcription factor RFX protects MHC class II genes against epigenetic silencing by DNA methylation. (Seguín-Estévez Q, De Palma R, Krawczyk M, Leimgruber E, Villard J, Picard C, Tagliamacco A, Abbate G, Gorski J, Nocera A, Reith W) J Immunol 2009 Aug 15;183(4):2545-53 PMID: 19620312 SCOPUS ID: 2-s2.0-70149125037 07/22/2009       14 Citations
  • A clonotype nomenclature for T cell receptors. (Yassai MB, Naumov YN, Naumova EN, Gorski J) Immunogenetics 2009 Jul;61(7):493-502 PMID: 19568742 PMCID: PMC2706371 SCOPUS ID: 2-s2.0-67650327072 07/02/2009       20 Citations
  • An accessible micro-capillary electrophoresis device using surface-tension-driven flow. (Mohanty SK, Warrick J, Gorski J, Beebe DJ) Electrophoresis 2009 May;30(9):1470-81 PMID: 19425002 PMCID: PMC2842211 SCOPUS ID: 2-s2.0-69249223221 05/09/2009       7 Citations
  • Last update: 08/30/2017
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