Medical College of Wisconsin
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Janet Sue Rader MD

Chairman, Professor

Institution: Medical College of Wisconsin
Department: Obstetrics and Gynecology
Division: Administration
Program: Obstetrics and Gynecology


Publications

  • Genomics of cervical cancer and the role of human papillomavirus pathobiology. (Uyar D, Rader J) Clin Chem 2014 Jan;60(1):144-6 PMID 24046199
  • A statement on abortion by 100 professors of obstetrics: 40 years later. (One Hundred Professors of Obstetrics and Gynecology) Contraception 2013 Oct;88(4):568-76 PMID 24034806
  • Genetic variations in EGFR and ERBB4 increase susceptibility to cervical cancer. (Ma D, Hovey RL, Zhang Z, Fye S, Huettner PC, Borecki IB, Rader JS) Gynecol Oncol 2013 Nov;131(2):445-50 PMID 23927961
  • Multicenter phase II trial of topotecan, cisplatin and bevacizumab for recurrent or persistent cervical cancer. (Zighelboim I, Wright JD, Gao F, Case AS, Massad LS, Mutch DG, Powell MA, Thaker PH, Eisenhauer EL, Cohn DE, Valea FA, Alvarez Secord A, Lippmann LT, Dehdashti F, Rader JS) Gynecol Oncol 2013 Jul;130(1):64-8 PMID 23591400
  • A statement on abortion by 100 professors of obstetrics: 40 years later. (One Hundred Professors of Obstetrics and Gynecology) Am J Obstet Gynecol 2013 Sep;209(3):193-9 PMID 23500455
  • Pathway index models for construction of patient-specific risk profiles. (Eng KH, Wang S, Bradley WH, Rader JS, Kendziorski C) Stat Med 2013 Apr 30;32(9):1524-35 PMID 23074142
  • Pathway-specific analysis of gene expression data identifies the PI3K/Akt pathway as a novel therapeutic target in cervical cancer. (Schwarz JK, Payton JE, Rashmi R, Xiang T, Jia Y, Huettner P, Rogers BE, Yang Q, Watson M, Rader JS, Grigsby PW) Clin Cancer Res 2012 Mar 1;18(5):1464-71 PMID 22235101
  • Integrated genomic analyses of ovarian carcinoma. (Cancer Genome Atlas Research Network) Nature 2011 Jun 30;474(7353):609-15 PMID 21720365
  • Cost-benefit of laparoscopic versus medical ovarian suppression in premenopausal breast cancer. (Hagemann AR, Zighelboim I, Odibo AO, Rader JS, Mutch DG, Powell MA) Breast J 2011 Jan-Feb;17(1):103-5 PMID 21155918
  • The effects of body mass index on complications and survival outcomes in patients with cervical carcinoma undergoing curative chemoradiation therapy. (Kizer NT, Thaker PH, Gao F, Zighelboim I, Powell MA, Rader JS, Mutch DG, Grigsby PW) Cancer 2011 Mar 1;117(5):948-56 PMID 20945318
  • HLA-Cw group 1 ligands for KIR increase susceptibility to invasive cervical cancer. (Martin MP, Borecki IB, Zhang Z, Nguyen L, Ma D, Gao X, Qi Y, Carrington M, Rader JS) Immunogenetics 2010 Dec;62(11-12):761-5 PMID 20857097
  • A Phase 1 study of UCN-01 in combination with irinotecan in patients with resistant solid tumor malignancies. (Fracasso PM, Williams KJ, Chen RC, Picus J, Ma CX, Ellis MJ, Tan BR, Pluard TJ, Adkins DR, Naughton MJ, Rader JS, Arquette MA, Fleshman JW, Creekmore AN, Goodner SA, Wright LP, Guo Z, Ryan CE, Tao Y, Soares EM, Cai SR, Lin L, Dancey J, Rudek MA, McLeod HL, Piwnica-Worms H) Cancer Chemother Pharmacol 2011 Jun;67(6):1225-37 PMID 20694727
  • Lymph node staging by positron emission tomography in cervical cancer: relationship to prognosis. (Kidd EA, Siegel BA, Dehdashti F, Rader JS, Mutch DG, Powell MA, Grigsby PW) J Clin Oncol 2010 Apr 20;28(12):2108-13 PMID 20308664
  • TP53, MDM2, NQO1, and susceptibility to cervical cancer. (Hu X, Zhang Z, Ma D, Huettner PC, Massad LS, Nguyen L, Borecki I, Rader JS) Cancer Epidemiol Biomarkers Prev 2010 Mar;19(3):755-61 PMID 20200430
  • A microRNA expression signature for cervical cancer prognosis. (Hu X, Schwarz JK, Lewis JS Jr, Huettner PC, Rader JS, Deasy JO, Grigsby PW, Wang X) Cancer Res 2010 Feb 15;70(4):1441-8 PMID 20124485
  • "Surgical Apgar Score" predicts postoperative complications after cytoreduction for advanced ovarian cancer. (Zighelboim I, Kizer N, Taylor NP, Case AS, Gao F, Thaker PH, Rader JS, Massad LS, Mutch DG, Powell MA) Gynecol Oncol 2010 Mar;116(3):370-3 PMID 20015540
  • 18F-fluorodeoxyglucose-positron emission tomography and pathologic tumor size in early-stage invasive cervical cancer. (Showalter TN, Miller TR, Huettner P, Rader J, Grigsby PW) Int J Gynecol Cancer 2009 Nov;19(8):1412-4 PMID 20009899
  • Polymorphisms in MMP9 and SIPA1 are associated with increased risk of nodal metastases in early-stage cervical cancer. (Brooks R, Kizer N, Nguyen L, Jaishuen A, Wanat K, Nugent E, Grigsby P, Allsworth JE, Rader JS) Gynecol Oncol 2010 Mar;116(3):539-43 PMID 19906411
  • Chemoradiation in locally advanced cervical carcinoma: an analysis of cisplatin dosing and other clinical prognostic factors. (Nugent EK, Case AS, Hoff JT, Zighelboim I, DeWitt LL, Trinkhaus K, Mutch DG, Thaker PH, Massad LS, Rader JS) Gynecol Oncol 2010 Mar;116(3):438-41 PMID 19896180
  • Clinical outcomes of definitive intensity-modulated radiation therapy with fluorodeoxyglucose-positron emission tomography simulation in patients with locally advanced cervical cancer. (Kidd EA, Siegel BA, Dehdashti F, Rader JS, Mutic S, Mutch DG, Powell MA, Grigsby PW) Int J Radiat Oncol Biol Phys 2010 Jul 15;77(4):1085-91 PMID 19880262
  • The value of perioperative imaging in patients with uterine sarcomas. (Nugent EK, Zighelboim I, Case AS, Gao F, Thaker PH, Rader JS, Mutch DG, Massad LS) Gynecol Oncol 2009 Oct;115(1):37-40 PMID 19577795
  • The accuracy of colposcopic grading for detection of high-grade cervical intraepithelial neoplasia. (Massad LS, Jeronimo J, Katki HA, Schiffman M, National Institutes of Health/American Society for Colposcopy and Cervical Pathology Research Group) J Low Genit Tract Dis 2009 Jul;13(3):137-44 PMID 19550210
  • Cervical cancer histology and tumor differentiation affect 18F-fluorodeoxyglucose uptake. (Kidd EA, Spencer CR, Huettner PC, Siegel BA, Dehdashti F, Rader JS, Grigsby PW) Cancer 2009 Aug 1;115(15):3548-54 PMID 19472399
  • ATR mutation in endometrioid endometrial cancer is associated with poor clinical outcomes. (Zighelboim I, Schmidt AP, Gao F, Thaker PH, Powell MA, Rader JS, Gibb RK, Mutch DG, Goodfellow PJ) J Clin Oncol 2009 Jul 1;27(19):3091-6 PMID 19470935
  • CD83 polymorphisms and cervical cancer risk. (Yu KJ, Rader JS, Borecki I, Zhang Z, Hildesheim A) Gynecol Oncol 2009 Aug;114(2):319-22 PMID 19446866
  • Long-term assessment of bladder and bowel dysfunction after radical hysterectomy. (Brooks RA, Wright JD, Powell MA, Rader JS, Gao F, Mutch DG, Wall LL) Gynecol Oncol 2009 Jul;114(1):75-9 PMID 19410279
  • Cardiac arrest during laparotomy with argon beam coagulation of metastatic ovarian cancer. (Kizer N, Zighelboim I, Rader JS) Int J Gynecol Cancer 2009 Feb;19(2):237-8 PMID 19395999
  • Oncogenic HPV infection interrupts the expression of tumor-suppressive miR-34a through viral oncoprotein E6. (Wang X, Wang HK, McCoy JP, Banerjee NS, Rader JS, Broker TR, Meyers C, Chow LT, Zheng ZM) RNA 2009 Apr;15(4):637-47 PMID 19258450
  • Sequential chemotherapy and irradiation in advanced stage endometrial cancer: A Gynecologic Oncology Group phase I trial of doxorubicin-cisplatin followed by whole abdomen irradiation. (Fowler JM, Brady WE, Grigsby PW, Cohn DE, Mannel RS, Rader JS) Gynecol Oncol 2009 Mar;112(3):553-7 PMID 19135232
  • A unified sample preparation protocol for proteomic and genomic profiling of cervical swabs to identify biomarkers for cervical cancer screening. (Rader JS, Malone JP, Gross J, Gilmore P, Brooks RA, Nguyen L, Crimmins DL, Feng S, Wright JD, Taylor N, Zighelboim I, Funk MC, Huettner PC, Ladenson JH, Gius D, Townsend RR) Proteomics Clin Appl 2008 Dec;2(12):1658-69 PMID 21136816
  • Surveillance FDG-PET detection of asymptomatic recurrences in patients with cervical cancer. (Brooks RA, Rader JS, Dehdashti F, Mutch DG, Powell MA, Thaker PH, Siegel BA, Grigsby PW) Gynecol Oncol 2009 Jan;112(1):104-9 PMID 18929403
  • Phase II evaluation of topotecan and navelbine in patients with recurrent ovarian, fallopian tube or primary peritoneal cancer. (Herzog TJ, Powell MA, Rader JS, Gibb RK, Lippmann L, Coleman RL, Mutch DG) Gynecol Oncol 2008 Dec;111(3):467-73 PMID 18834619
  • Effects of cancer treatment on ovarian function. (Stroud JS, Mutch D, Rader J, Powell M, Thaker PH, Grigsby PW) Fertil Steril 2009 Aug;92(2):417-27 PMID 18774559
  • Aberrant expression of oncogenic and tumor-suppressive microRNAs in cervical cancer is required for cancer cell growth. (Wang X, Tang S, Le SY, Lu R, Rader JS, Meyers C, Zheng ZM) PLoS One 2008;3(7):e2557 PMID 18596939
  • Differential display identifies overexpression of the USP36 gene, encoding a deubiquitinating enzyme, in ovarian cancer. (Li J, Olson LM, Zhang Z, Li L, Bidder M, Nguyen L, Pfeifer J, Rader JS) Int J Med Sci 2008;5(3):133-42 PMID 18566677
  • Phase I study and preliminary pharmacology of the novel innate immune modulator rBBX-01 in gynecologic cancers. (Rader JS, Aylsworth CF, Juckett DA, Mutch DG, Powell MA, Lippmann L, Dimitrov NV) Clin Cancer Res 2008 May 15;14(10):3089-97 PMID 18483376
  • Identification of novel methylation markers in cervical cancer using restriction landmark genomic scanning. (Wang SS, Smiraglia DJ, Wu YZ, Ghosh S, Rader JS, Cho KR, Bonfiglio TA, Nayar R, Plass C, Sherman ME) Cancer Res 2008 Apr 1;68(7):2489-97 PMID 18381458
  • Prognostic factors associated with response in platinum retreatment of platinum-resistant ovarian cancer. (Nguyen TT, Wright JD, Powell MA, Gibb RK, Rader JS, Allsworth JE, Mutch DG) Int J Gynecol Cancer 2008 Nov-Dec;18(6):1194-9 PMID 18217964
  • CD83 gene polymorphisms increase susceptibility to human invasive cervical cancer. (Zhang Z, Borecki I, Nguyen L, Ma D, Smith K, Huettner PC, Mutch DG, Herzog TJ, Gibb RK, Powell MA, Grigsby PW, Massad LS, Hernandez E, Judson PL, Swisher EM, Crowder S, Li J, Gerhard DS, Rader JS) Cancer Res 2007 Dec 1;67(23):11202-8 PMID 18056445
  • Acute toxicity of postoperative IMRT and chemotherapy for endometrial cancer. (Tierney RM, Powell MA, Mutch DG, Gibb RK, Rader JS, Grigsby PW) Radiat Med 2007 Nov;25(9):439-45 PMID 18026901
  • Bevacizumab therapy in patients with recurrent uterine neoplasms. (Wright JD, Powell MA, Rader JS, Mutch DG, Gibb RK) Anticancer Res 2007 Sep-Oct;27(5B):3525-8 PMID 17972512
  • Evaluation of candidate methylation markers to detect cervical neoplasia. (Shivapurkar N, Sherman ME, Stastny V, Echebiri C, Rader JS, Nayar R, Bonfiglio TA, Gazdar AF, Wang SS) Gynecol Oncol 2007 Dec;107(3):549-53 PMID 17894941
  • Effect of a T0 radical hysterectomy specimen on survival for early stage cervical cancer. (Wright JD, Grigsby PW, Rader JS, Mutch DG, Powell MA, Gao F, Gibb RK) Gynecol Oncol 2007 Nov;107(2):280-4 PMID 17698175
  • Profiling microdissected epithelium and stroma to model genomic signatures for cervical carcinogenesis accommodating for covariates. (Gius D, Funk MC, Chuang EY, Feng S, Huettner PC, Nguyen L, Bradbury CM, Mishra M, Gao S, Buttin BM, Cohn DE, Powell MA, Horowitz NS, Whitcomb BP, Rader JS) Cancer Res 2007 Aug 1;67(15):7113-23 PMID 17671178
  • Utility of parametrectomy for early stage cervical cancer treated with radical hysterectomy. (Wright JD, Grigsby PW, Brooks R, Powell MA, Gibb RK, Gao F, Rader JS, Mutch DG) Cancer 2007 Sep 15;110(6):1281-6 PMID 17654664
  • A multi-institutional evaluation of factors predictive of toxicity and efficacy of bevacizumab for recurrent ovarian cancer. (Wright JD, Secord AA, Numnum TM, Rocconi RP, Powell MA, Berchuck A, Alvarez RD, Gibb RK, Trinkaus K, Rader JS, Mutch DG) Int J Gynecol Cancer 2008 May-Jun;18(3):400-6 PMID 17645510
  • Microsatellite instability and epigenetic inactivation of MLH1 and outcome of patients with endometrial carcinomas of the endometrioid type. (Zighelboim I, Goodfellow PJ, Gao F, Gibb RK, Powell MA, Rader JS, Mutch DG) J Clin Oncol 2007 May 20;25(15):2042-8 PMID 17513808
  • External radiotherapy versus vaginal brachytherapy for patients with intermediate risk endometrial cancer. (Lin LL, Mutch DG, Rader JS, Powell MA, Grigsby PW) Gynecol Oncol 2007 Jul;106(1):215-20 PMID 17482665
  • Comparison of high-dose-rate and low-dose-rate brachytherapy in the treatment of endometrial carcinoma. (Fayed A, Mutch DG, Rader JS, Gibb RK, Powell MA, Wright JD, Elnaqa I, Zoberi I, Grigsby PW) Int J Radiat Oncol Biol Phys 2007 Feb 1;67(2):480-4 PMID 17141980
  • Body mass index: relationship to clinical, pathologic and features of microsatellite instability in endometrial cancer. (McCourt CK, Mutch DG, Gibb RK, Rader JS, Goodfellow PJ, Trinkaus K, Powell MA) Gynecol Oncol 2007 Mar;104(3):535-9 PMID 17109938
  • Outcomes in 24 selected patients with stage IVB cervical cancer and excellent performance status treated with radiotherapy and chemotherapy. (Zighelboim I, Taylor NP, Powell MA, Gibb RK, Rader JS, Mutch DG, Grigsby PW) Radiat Med 2006 Nov;24(9):625-30 PMID 17111271
  • Human papillomaviruses target the double-stranded RNA protein kinase pathway. (Hebner CM, Wilson R, Rader J, Bidder M, Laimins LA) J Gen Virol 2006 Nov;87(Pt 11):3183-93 PMID 17030851
  • Cervical cancer prevention in the era of prophylactic vaccines: a preview for gynecologic oncologists. (Society of Gynecologic Oncologists Education Resource Panel Writing group, Collins Y, Einstein MH, Gostout BS, Herzog TJ, Massad LS, Rader JS, Wright J) Gynecol Oncol 2006 Sep;102(3):552-62 PMID 16979432
  • Cervical tissue collection methods for RNA preservation: comparison of snap-frozen, ethanol-fixed, and RNAlater-fixation. (Wang SS, Sherman ME, Rader JS, Carreon J, Schiffman M, Baker CC) Diagn Mol Pathol 2006 Sep;15(3):144-8 PMID 16932069
  • MLH3 mutation in endometrial cancer. (Taylor NP, Powell MA, Gibb RK, Rader JS, Huettner PC, Thibodeau SN, Mutch DG, Goodfellow PJ) Cancer Res 2006 Aug 1;66(15):7502-8 PMID 16885347
  • Colposcopic accuracy of obstetrics and gynecology residents. (Baum ME, Rader JS, Gibb RK, McAlister RP, Powell MA, Mutch DG, Gao F, Wright JD) Gynecol Oncol 2006 Dec;103(3):966-70 PMID 16875717
  • DNA mismatch repair and TP53 defects are early events in uterine carcinosarcoma tumorigenesis. (Taylor NP, Zighelboim I, Huettner PC, Powell MA, Gibb RK, Rader JS, Mutch DG, Edmonston TB, Goodfellow PJ) Mod Pathol 2006 Oct;19(10):1333-8 PMID 16810312
  • Phase II evaluation of a 3-day infusion of topotecan in patients with recurrent ovarian or primary peritoneal cancer. (Herzog TJ, Powell MA, Rader JS, Gibb R, Mutch DG) Gynecol Oncol 2006 Nov;103(2):637-41 PMID 16781766
  • Bevacizumab combination therapy in recurrent, platinum-refractory, epithelial ovarian carcinoma: A retrospective analysis. (Wright JD, Hagemann A, Rader JS, Viviano D, Gibb RK, Norris L, Mutch DG, Powell MA) Cancer 2006 Jul 1;107(1):83-9 PMID 16736514
  • Gene expression patterns in advanced human cervical cancer. (Grigsby PW, Watson M, Powell MA, Zhang Z, Rader JS) Int J Gynecol Cancer 2006 Mar-Apr;16(2):562-7 PMID 16681726
  • CA-125 response in patients with recurrent ovarian or primary peritoneal cancer treated with pegylated liposomal doxorubicin or topotecan. (Gossner G, Coleman RL, Mutch DG, Horowitz NS, Rader JS, Gibb RK, Powell MA, Herzog TJ) Gynecol Oncol 2006 Oct;103(1):212-8 PMID 16677696
  • Bevacizumab combination therapy in heavily pretreated, recurrent cervical cancer. (Wright JD, Viviano D, Powell MA, Gibb RK, Mutch DG, Grigsby PW, Rader JS) Gynecol Oncol 2006 Nov;103(2):489-93 PMID 16647106
  • Identification of chromosomal alterations important in the development of cervical intraepithelial neoplasia and invasive carcinoma using alignment of DNA microarray data. (Fitzpatrick MA, Funk MC, Gius D, Huettner PC, Zhang Z, Bidder M, Ma D, Powell MA, Rader JS) Gynecol Oncol 2006 Nov;103(2):458-62 PMID 16647105
  • Aberrant promoter methylation and silencing of the POU2F3 gene in cervical cancer. (Zhang Z, Huettner PC, Nguyen L, Bidder M, Funk MC, Li J, Rader JS) Oncogene 2006 Aug 31;25(39):5436-45 PMID 16607278
  • Human papillomavirus triage for young women with atypical squamous cells of undetermined significance. (Wright JD, Rader JS, Davila R, Powell MA, Mutch DG, Gao F, Gibb RK) Obstet Gynecol 2006 Apr;107(4):822-9 PMID 16582118
  • Long-term outcome of women who undergo panniculectomy at the time of gynecologic surgery. (Wright JD, Rosenbush EJ, Powell MA, Rader JS, Mutch DG, Gao F, Gibb RK) Gynecol Oncol 2006 Jul;102(1):86-91 PMID 16406112
  • Preoperative lymph node staging of early-stage cervical carcinoma by [18F]-fluoro-2-deoxy-D-glucose-positron emission tomography. (Wright JD, Dehdashti F, Herzog TJ, Mutch DG, Huettner PC, Rader JS, Gibb RK, Powell MA, Gao F, Siegel BA, Grigsby PW) Cancer 2005 Dec 1;104(11):2484-91 PMID 16270319
  • Relationship of ovarian neoplasms and body mass index. (Wright JD, Powell MA, Mutch DG, Rader JS, Gibb RK, Gao F, Herzog TJ) J Reprod Med 2005 Aug;50(8):595-602 PMID 16220765
  • Resource utilization for ovarian cancer patients at the end of life: how much is too much? (Lewin SN, Buttin BM, Powell MA, Gibb RK, Rader JS, Mutch DG, Herzog TJ) Gynecol Oncol 2005 Nov;99(2):261-6 PMID 16140364
  • Cervical sarcomas: an analysis of incidence and outcome. (Wright JD, Rosenblum K, Huettner PC, Mutch DG, Rader JS, Powell MA, Gibb RK) Gynecol Oncol 2005 Nov;99(2):348-51 PMID 16051326
  • Cervical dysplasia in adolescents. (Wright JD, Davila RM, Pinto KR, Merritt DF, Gibb RK, Rader JS, Mutch DG, Gao F, Powell MA) Obstet Gynecol 2005 Jul;106(1):115-20 PMID 15994625
  • FDG-PET evaluation of vaginal carcinoma. (Lamoreaux WT, Grigsby PW, Dehdashti F, Zoberi I, Powell MA, Gibb RK, Rader JS, Mutch DG, Siegel BA) Int J Radiat Oncol Biol Phys 2005 Jul 1;62(3):733-7 PMID 15936553
  • Human papillomavirus type and tobacco use as predictors of survival in early stage cervical carcinoma. (Wright JD, Li J, Gerhard DS, Zhang Z, Huettner PC, Powell MA, Gibb RK, Herzog TJ, Mutch DG, Trinkaus KM, Rader JS) Gynecol Oncol 2005 Jul;98(1):84-91 PMID 15894364
  • Fine mapping and evaluation of candidate genes for cervical cancer on 11q23. (Zhang Z, Gerhard DS, Nguyen L, Li J, Traugott A, Huettner PC, Rader JS) Genes Chromosomes Cancer 2005 May;43(1):95-103 PMID 15672406
  • Cervix carcinoma, concurrent chemoradiotherapy, and salvage of isolated paraaortic lymph node recurrence. (Singh AK, Grigsby PW, Rader JS, Mutch DG, Powell MA) Int J Radiat Oncol Biol Phys 2005 Feb 1;61(2):450-5 PMID 15667966
  • Lack of benefit of concurrent chemotherapy in patients with cervical cancer and negative lymph nodes by FDG-PET. (Grigsby PW, Mutch DG, Rader J, Herzog TJ, Zoberi I, Siegel BA, Dehdashti F) Int J Radiat Oncol Biol Phys 2005 Feb 1;61(2):444-9 PMID 15667965
  • IGSF4 promoter methylation and expression silencing in human cervical cancer. (Li J, Zhang Z, Bidder M, Funk MC, Nguyen L, Goodfellow PJ, Rader JS) Gynecol Oncol 2005 Jan;96(1):150-8 PMID 15589594
  • Prospective evaluation of FDG-PET for detecting pelvic and para-aortic lymph node metastasis in uterine corpus cancer. (Horowitz NS, Dehdashti F, Herzog TJ, Rader JS, Powell MA, Gibb RK, Grigsby PW, Siegel BA, Mutch DG) Gynecol Oncol 2004 Dec;95(3):546-51 PMID 15581961
  • Cervical carcinoma in the elderly: an analysis of patterns of care and outcome. (Wright JD, Gibb RK, Geevarghese S, Powell MA, Herzog TJ, Mutch DG, Grigsby PW, Gao F, Trinkaus KM, Rader JS) Cancer 2005 Jan 1;103(1):85-91 PMID 15540239
  • Phase I study of docetaxel in combination with the P-glycoprotein inhibitor, zosuquidar, in resistant malignancies. (Fracasso PM, Goldstein LJ, de Alwis DP, Rader JS, Arquette MA, Goodner SA, Wright LP, Fears CL, Gazak RJ, Andre VA, Burgess MF, Slapak CA, Schellens JH) Clin Cancer Res 2004 Nov 1;10(21):7220-8 PMID 15534095
  • A comparison of stages IB1 and IB2 cervical cancers treated with radical hysterectomy. Is size the real difference? (Rutledge TL, Kamelle SA, Tillmanns TD, Gould NS, Wright JD, Cohn DE, Herzog TJ, Rader JS, Gold MA, Johnson GA, Walker JL, Mannel RS, McMeekin DS) Gynecol Oncol 2004 Oct;95(1):70-6 PMID 15385112
  • Expression and localization of GRP75 in human epithelial tumors and normal tissues. (Srokowski T, Pfeifer JD, Li J, Olson LM, Rader JS) Appl Immunohistochem Mol Morphol 2004 Jun;12(2):132-8 PMID 15354738
  • Panniculectomy: improving lymph node yield in morbidly obese patients with endometrial neoplasms. (Wright JD, Powell MA, Herzog TJ, Mutch DG, Rader JS, Gao F, Gibb RK) Gynecol Oncol 2004 Aug;94(2):436-41 PMID 15297185
  • Surgical-pathological predictors of disease-free survival and risk groupings for IB2 cervical cancer: do the traditional models still apply? (Kamelle SA, Rutledge TL, Tillmanns TD, Gould NS, Cohn DE, Wright J, Herzog TJ, Rader JS, Gold MA, Johnson GA, Walker JL, Mannel RS, McMeekin DS) Gynecol Oncol 2004 Aug;94(2):249-55 PMID 15297159
  • Lymph node control in cervical cancer. (Grigsby PW, Singh AK, Siegel BA, Dehdashti F, Rader J, Zoberi I) Int J Radiat Oncol Biol Phys 2004 Jul 1;59(3):706-12 PMID 15183474
  • Posttherapy [18F] fluorodeoxyglucose positron emission tomography in carcinoma of the cervix: response and outcome. (Grigsby PW, Siegel BA, Dehdashti F, Rader J, Zoberi I) J Clin Oncol 2004 Jun 1;22(11):2167-71 PMID 15169804
  • Penetrance and expressivity of MSH6 germline mutations in seven kindreds not ascertained by family history. (Buttin BM, Powell MA, Mutch DG, Babb SA, Huettner PC, Edmonston TB, Herzog TJ, Rader JS, Gibb RK, Whelan AJ, Goodfellow PJ) Am J Hum Genet 2004 Jun;74(6):1262-9 PMID 15098177
  • Double cervix with bilateral and synchronous HSIL associated with different high-risk HPV types. A case report. (Pinto KR, Lu DW, Rader JS, Dávila RM) Acta Cytol 2004 Mar-Apr;48(2):273-7 PMID 15085767
  • Synchronous ovarian metastases at the time of laparotomy for colon cancer. (Wright JD, Powell MA, Mutch DG, Rader JS, Gibb RK, Huettner PC, Herzog TJ) Gynecol Oncol 2004 Mar;92(3):851-5 PMID 14984952
  • Increased risk for hereditary nonpolyposis colorectal cancer-associated synchronous and metachronous malignancies in patients with microsatellite instability-positive endometrial carcinoma lacking MLH1 promoter methylation. (Buttin BM, Powell MA, Mutch DG, Rader JS, Herzog TJ, Gibb RK, Huettner P, Edmonston TB, Goodfellow PJ) Clin Cancer Res 2004 Jan 15;10(2):481-90 PMID 14760069
  • Denaturing high-performance liquid chromatography for detecting and typing genital human papillomavirus. (Li J, Gerhard DS, Zhang Z, Huettner PC, Wright J, Nguyen L, Lu D, Rader JS) J Clin Microbiol 2003 Dec;41(12):5563-71 PMID 14662941
  • A phase II study to determine the efficacy and tolerability of intravenous ZD9331 in heavily pretreated patients with ovarian cancer. (Rader JS, Clarke-Pearson D, Moore M, Carson L, Holloway R, Kao MS, Wiznitzer I, Douglass EC) Gynecol Oncol 2003 Nov;91(2):318-25 PMID 14599861
  • A randomized phase II evaluation of bryostatin-1 (NSC #339555) in persistent or recurrent squamous cell carcinoma of the cervix: A Gynecologic Oncology Group Study. (Armstrong DK, Blessing JA, Rader J, Sorosky JI, Gynecologic Oncology Group Study) Invest New Drugs 2003 Nov;21(4):453-7 PMID 14586213
  • Acute abdominal pain with a calcified pelvic mass. (Wright JD, Powell MA, Rader JS, Pfeifer JD, Huettner PC, Merritt DF) J Pediatr Adolesc Gynecol 2003 Aug;16(4):237-41 PMID 14550387
  • Liquid-based cytology for the postirradiation surveillance of women with gynecologic malignancies. (Wright JD, Herzog TJ, Mutch DG, Gibb RK, Rader JS, Davila RM, Cohn DE) Gynecol Oncol 2003 Oct;91(1):134-8 PMID 14529673
  • A relationship between methylenetetrahydrofolate reductase variants and the development of invasive cervical cancer. (Gerhard DS, Nguyen LT, Zhang ZY, Borecki IB, Coleman BI, Rader JS) Gynecol Oncol 2003 Sep;90(3):560-5 PMID 13678724
  • Phase I dose and sequencing study of pegylated liposomal doxorubicin and docetaxel in patients with advanced malignancies. (Fracasso PM, Rodriguez LC, Herzog TJ, Fears CL, Goodner SA, Govindan R, Picus J, Rader JS, Tan BR, Arquette MA) Cancer 2003 Aug 1;98(3):610-7 PMID 12879480
  • Frequent HOXA11 and THBS2 promoter methylation, and a methylator phenotype in endometrial adenocarcinoma. (Whitcomb BP, Mutch DG, Herzog TJ, Rader JS, Gibb RK, Goodfellow PJ) Clin Cancer Res 2003 Jun;9(6):2277-87 PMID 12796396
  • Prevalence of defective DNA mismatch repair and MSH6 mutation in an unselected series of endometrial cancers. (Goodfellow PJ, Buttin BM, Herzog TJ, Rader JS, Gibb RK, Swisher E, Look K, Walls KC, Fan MY, Mutch DG) Proc Natl Acad Sci U S A 2003 May 13;100(10):5908-13 PMID 12732731
  • Primary peritoneal carcinoma presenting as adenocarcinoma on a Pap smear. A case report. (Wright JD, Horowitz NS, Rader JS) J Reprod Med 2002 Nov;47(11):933-5 PMID 12497684
  • Phase I study of rubitecan and gemcitabine in patients with advanced malignancies. (Fracasso PM, Rader JS, Govindan R, Herzog TJ, Arquette MA, Denes A, Mutch DG, Picus J, Tan BR, Fears CL, Goodner SA, Sun SL) Ann Oncol 2002 Nov;13(11):1819-25 PMID 12419757
  • MSI in endometrial carcinoma: absence of MLH1 promoter methylation is associated with increased familial risk for cancers. (Whelan AJ, Babb S, Mutch DG, Rader J, Herzog TJ, Todd C, Ivanovich JL, Goodfellow PJ) Int J Cancer 2002 Jun 10;99(5):697-704 PMID 12115503
  • Ribosomal DNA methylation in patients with endometrial carcinoma: an independent prognostic marker. (Powell MA, Mutch DG, Rader JS, Herzog TJ, Huang TH, Goodfellow PJ) Cancer 2002 Jun 1;94(11):2941-52 PMID 12115383
  • The significance of pneumatosis intestinalis or bowel perforation in patients with gynecologic malignancies. (Horowitz NS, Cohn DE, Herzog TJ, Mutch DG, Rader JS, Bhalla S, Gibb RK) Gynecol Oncol 2002 Jul;86(1):79-84 PMID 12079304
  • Microsatellite instability, MLH1 promoter methylation, and loss of mismatch repair in endometrial cancer and concomitant atypical hyperplasia. (Horowitz N, Pinto K, Mutch DG, Herzog TJ, Rader JS, Gibb R, Bocker-Edmonston T, Goodfellow PJ) Gynecol Oncol 2002 Jul;86(1):62-8 PMID 12079302
  • Evaluation of the family history collection process and the accuracy of cancer reporting among a series of women with endometrial cancer. (Ivanovich J, Babb S, Goodfellow P, Mutch D, Herzog T, Rader J, Whelan A) Clin Cancer Res 2002 Jun;8(6):1849-56 PMID 12060627
  • Mutation screening analysis of the retinoblastoma related gene RB2/p130 in sporadic ovarian cancer and head and neck squamous cell cancer. (Alvi AJ, Hogg R, Rader JS, Kuo MJ, Maher ER, Latif F) Mol Pathol 2002 Jun;55(3):153-5 PMID 12032225
  • Utility and cost-effectiveness of preoperative autologous blood donation in gynecologic and gynecologic oncology patients. (Horowitz NS, Gibb RK, Menegakis NE, Mutch DG, Rader JS, Herzog TJ) Obstet Gynecol 2002 May;99(5 Pt 1):771-6 PMID 11978286
  • Prospective evaluation of positron emission tomography for the detection of groin node metastases from vulvar cancer. (Cohn DE, Dehdashti F, Gibb RK, Mutch DG, Rader JS, Siegel BA, Herzog TJ) Gynecol Oncol 2002 Apr;85(1):179-84 PMID 11925141
  • Randomized trial of cisplatin and ifosfamide with or without bleomycin in squamous carcinoma of the cervix: a gynecologic oncology group study. (Bloss JD, Blessing JA, Behrens BC, Mannel RS, Rader JS, Sood AK, Markman M, Benda J) J Clin Oncol 2002 Apr 1;20(7):1832-7 PMID 11919241
  • Use of complementary and alternative medicine among women with gynecologic cancers. (Swisher EM, Cohn DE, Goff BA, Parham J, Herzog TJ, Rader JS, Mutch DG) Gynecol Oncol 2002 Mar;84(3):363-7 PMID 11855870
  • Phase II trial of pyrazoloacridine in patients with persistent or recurrent endometrial carcinoma: a Gynecologic Oncology Group Study. (Plaxe SC, Blessing JA, Husseinzadeh N, Webster KD, Rader JS, Dunton CJ) Gynecol Oncol 2002 Feb;84(2):241-4 PMID 11812081
  • Epithelial ovarian tumors of low malignant potential: the role of microinvasion. (Buttin BM, Herzog TJ, Powell MA, Rader JS, Mutch DG) Obstet Gynecol 2002 Jan;99(1):11-7 PMID 11777503
  • Role of the ultrasonic surgical aspirator in gynecology. (Horowitz NS, Rader JS) Obstet Gynecol Clin North Am 2001 Dec;28(4):775-90 PMID 11766151
  • Genotypic and phenotypic progression in endometrial tumorigenesis: determining when defects in DNA mismatch repair and KRAS2 occur. (Cohn DE, Mutch DG, Herzog TJ, Rader JS, Dintzis SM, Gersell DJ, Todd CR, Goodfellow PJ) Genes Chromosomes Cancer 2001 Dec;32(4):295-301 PMID 11746970
  • Factors predicting subcutaneous implanted central venous port function: the relationship between catheter tip location and port failure in patients with gynecologic malignancies. (Cohn DE, Mutch DG, Rader JS, Farrell M, Awantang R, Herzog TJ) Gynecol Oncol 2001 Dec;83(3):533-6 PMID 11733967
  • Microsatellite instability and mutational analysis of transforming growth factor beta receptor type II gene (TGFBR2) in sporadic ovarian cancer. (Alvi AJ, Rader JS, Broggini M, Latif F, Maher ER) Mol Pathol 2001 Aug;54(4):240-3 PMID 11477138
  • Loss of heterozygosity at 11q23.3 in vasculoinvasive and metastatic squamous cell carcinoma of the cervix. (O'sullivan MJ, Rader JS, Gerhard DS, Li Y, Trinkaus KM, Gersell DJ, Huettner PC) Hum Pathol 2001 May;32(5):475-8 PMID 11381364
  • Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumours. (Agathanggelou A, Honorio S, Macartney DP, Martinez A, Dallol A, Rader J, Fullwood P, Chauhan A, Walker R, Shaw JA, Hosoe S, Lerman MI, Minna JD, Maher ER, Latif F) Oncogene 2001 Mar 22;20(12):1509-18 PMID 11313894
  • Prophylactic oophorectomy and ovarian cancer surveillance. Patient perceptions and satisfaction. (Swisher EM, Babb S, Whelan A, Mutch DG, Rader JS) J Reprod Med 2001 Feb;46(2):87-94 PMID 11255821
  • Cyclooxygenase-2 is overexpressed in human cervical cancer. (Kulkarni S, Rader JS, Zhang F, Liapis H, Koki AT, Masferrer JL, Subbaramaiah K, Dannenberg AJ) Clin Cancer Res 2001 Feb;7(2):429-34 PMID 11234900
  • No evidence for BCL10 mutation in endometrial cancers with microsatellite instability. (Cohn D, Mutch D, Elbendary A, Rader J, Herzog T, Goodfellow P) Hum Mutat 2001 Feb;17(2):117-21 PMID 11180594
  • Radiation therapy for carcinoma of the cervix with biopsy-proven positive para-aortic lymph nodes. (Grigsby PW, Perez CA, Chao KS, Herzog T, Mutch DG, Rader J) Int J Radiat Oncol Biol Phys 2001 Mar 1;49(3):733-8 PMID 11172956
  • Clinical significance of microsatellite instability in endometrial carcinoma. (Basil JB, Goodfellow PJ, Rader JS, Mutch DG, Herzog TJ) Cancer 2000 Oct 15;89(8):1758-64 PMID 11042571
  • Radical hysterectomy for cervical cancer in obese women. (Cohn DE, Swisher EM, Herzog TJ, Rader JS, Mutch DG) Obstet Gynecol 2000 Nov;96(5 Pt 1):727-31 PMID 11042308
  • Absence of PTEN repeat tract mutation in endometrial cancers with microsatellite instability. (Cohn DE, Basil JB, Venegoni AR, Mutch DG, Rader JS, Herzog TJ, Gersell DJ, Goodfellow PJ) Gynecol Oncol 2000 Oct;79(1):101-6 PMID 11006040
  • Management of women at risk for malignancy. (Basil JB, Rader JS) Curr Opin Oncol 2000 Sep;12(5):508-13 PMID 10975560
  • Atypical clustering of gynecologic malignancies: A family study including molecular analysis of candidate genes. (Cohn DE, Babb S, Whelan AJ, Mutch DG, Herzog TJ, Rader JS, Elbendary A, Goodfellow PJ) Gynecol Oncol 2000 Apr;77(1):18-25 PMID 10739686
  • Cervical cancer suppressor gene is within 1 cM on 6p23. (Rader JS, Li Y, Huettner PC, Xu Z, Gerhard DS) Genes Chromosomes Cancer 2000 Apr;27(4):373-9 PMID 10719367
  • Evaluation of gemcitabine in patients with squamous cell carcinoma of the cervix: a Phase II study of the gynecologic oncology group. (Schilder RJ, Blessing JA, Morgan M, Mangan CE, Rader JS) Gynecol Oncol 2000 Feb;76(2):204-7 PMID 10637071
  • Association between DQB1 and cervical cancer in patients with human papillomavirus and family controls. (Neuman RJ, Huettner PC, Li L, Mardis ER, Duffy BF, Wilson RK, Rader JS) Obstet Gynecol 2000 Jan;95(1):134-40 PMID 10636516
  • Lack of effect of tumor size on the prognosis of carcinoma of the uterine cervix Stage IB and IIA treated with preoperative irradiation and surgery. (Grigsby PW, Perez CA, Chao KS, Elbendary A, Herzog TJ, Rader JS, Mutch DG) Int J Radiat Oncol Biol Phys 1999 Oct 1;45(3):645-51 PMID 10524418
  • Detailed genetic and physical mapping of tumor suppressor loci on chromosome 3p in ovarian cancer. (Fullwood P, Marchini S, Rader JS, Martinez A, Macartney D, Broggini M, Morelli C, Barbanti-Brodano G, Maher ER, Latif F) Cancer Res 1999 Sep 15;59(18):4662-7 PMID 10493522
  • Mutational analysis of the PMS2 gene in sporadic endometrial cancers with microsatellite instability. (Basil JB, Swisher EM, Herzog TJ, Rader JS, Elbendary A, Mutch DG, Goodfellow PJ) Gynecol Oncol 1999 Sep;74(3):395-9 PMID 10479499
  • Differences in patterns of TP53 and KRAS2 mutations in a large series of endometrial carcinomas with or without microsatellite instability. (Swisher EM, Peiffer-Schneider S, Mutch DG, Herzog TJ, Rader JS, Elbendary A, Goodfellow PJ) Cancer 1999 Jan 1;85(1):119-26 PMID 9921983
  • Cancer among first-degree relatives of probands with invasive and borderline ovarian cancer. (Rader JS, Neuman RJ, Brady J, Babb S, Temple S, Kost E, Mutch DG, Herzog TJ) Obstet Gynecol 1998 Oct;92(4 Pt 1):589-95 PMID 9764634
  • Mapping an endometrial cancer tumor suppressor gene at 10q25 and development of a bacterial clone contig for the consensus deletion interval. (Peiffer-Schneider S, Noonan FC, Mutch DG, Simpkins SB, Herzog T, Rader J, Elbendary A, Gersell DJ, Call K, Goodfellow PJ) Genomics 1998 Aug 15;52(1):9-16 PMID 9740666
  • Analysis of MSH3 in endometrial cancers with defective DNA mismatch repair. (Swisher EM, Mutch DG, Herzog TJ, Rader JS, Kowalski LD, Elbendary A, Goodfellow PJ) J Soc Gynecol Investig 1998 Jul-Aug;5(4):210-6 PMID 9699180
  • Cervical intraepithelial neoplasia III shows frequent allelic loss in 3p and 6p. (Rader JS, Gerhard DS, O'Sullivan MJ, Li Y, Li L, Liapis H, Huettner PC) Genes Chromosomes Cancer 1998 May;22(1):57-65 PMID 9591635
  • Loss of heterozygosity in clinical stage IB cervical carcinoma: relationship with clinical and histopathologic features. (Huettner PC, Gerhard DS, Li L, Gersell DJ, Dunnigan K, Kamarasova T, Rader JS) Hum Pathol 1998 Apr;29(4):364-70 PMID 9563786
  • Topotecan in platinum- and paclitaxel-resistant ovarian cancer. (Swisher EM, Mutch DG, Rader JS, Elbendary A, Herzog TJ) Gynecol Oncol 1997 Sep;66(3):480-6 PMID 9299264
  • Expression of alpha(v)beta3 integrin is less frequent in ovarian epithelial tumors of low malignant potential in contrast to ovarian carcinomas. (Liapis H, Adler LM, Wick MR, Rader JS) Hum Pathol 1997 Apr;28(4):443-9 PMID 9104944
  • Mutational analysis of MLH1 and MSH2 in 25 prospectively-acquired RER+ endometrial cancers. (Kowalski LD, Mutch DG, Herzog TJ, Rader JS, Goodfellow PJ) Genes Chromosomes Cancer 1997 Mar;18(3):219-27 PMID 9071575
  • Allelotyping of all chromosomal arms in invasive cervical cancer. (Rader JS, Kamarasova T, Huettner PC, Li L, Li Y, Gerhard DS) Oncogene 1996 Dec 19;13(12):2737-41 PMID 9000149
  • Potential of cervical electrosurgical excision procedure for diagnosis and treatment of cervical intraepithelial neoplasia. (Herzog TJ, Williams S, Adler LM, Rader JS, Kubiniec RT, Camel HM, Mutch DG) Gynecol Oncol 1995 Jun;57(3):286-93 PMID 7774831
  • Ovarian artery pseudoaneurysm: diagnosis by Doppler sonography and treatment with transcatheter embolization. (Ball RH, Picus D, Goyal RK, Wilson DB, Rader JS) J Ultrasound Med 1995 Mar;14(3):250-2 PMID 7760472
  • Analysis of exposure times and dose escalation of paclitaxel in ovarian cancer cell lines. (Adler LM, Herzog TJ, Williams S, Rader JS, Mutch DG) Cancer 1994 Oct 1;74(7):1891-8 PMID 7915965
  • In situ localization of parathyroid hormone-like protein and mRNA in intraepithelial neoplasia and invasive carcinoma of the uterine cervix. (Liapis H, Crouch EC, Roby J, Rader JS) Hum Pathol 1993 Oct;24(10):1058-66 PMID 8406415
  • A comparison of wound healing after epithelial resection by ultrasonic surgical aspiration and ablation by the carbon dioxide laser. (Rader JS, Rest EB, Farmer ER, Rosenshein NB) Gynecol Oncol 1992 Sep;46(3):351-6 PMID 1526514
  • Therapeutic advances in ovarian cancer. (Rader JS) Curr Opin Obstet Gynecol 1992 Feb;4(1):120-7 PMID 1543823
  • HPV-16 viral transcripts in vulvar neoplasia: preliminary studies. (Park JS, Rader JS, Wu TC, Laimins LA, Currie JL, Kurman RJ, Shah KV) Gynecol Oncol 1991 Sep;42(3):250-5 PMID 1659554
  • Retroperitoneal lymphatic involvement with epithelial ovarian tumors of low malignant potential. (Leake JF, Rader JS, Woodruff JD, Rosenshein NB) Gynecol Oncol 1991 Aug;42(2):124-30 PMID 1894170
  • Detection of transcripts of human papillomaviruses 16 and 18 in cancer-derived cell lines and cervical biopsies by enzyme immunoassay for DNA-RNA hybrids following solution hybridization. (Coutlée F, Shah KV, Rader JS, Currie JL, Viscidi RP) J Clin Microbiol 1991 May;29(5):968-74 PMID 1647410
  • Ultrasonic surgical aspiration in the treatment of vulvar disease. (Rader JS, Leake JF, Dillon MB, Rosenshein NB) Obstet Gynecol 1991 Apr;77(4):573-6 PMID 2002980
  • Atypical squamous cells. A case-series study of the association between papanicolaou smear results and human papillomavirus DNA genotype. (Rader JS, Rosenzweig BA, Spirtas R, Padleckas R, Javaheri G, Gerardo L, Laimins LA) J Reprod Med 1991 Apr;36(4):291-7 PMID 1649307
  • Ileal hemorrhage caused by a parasitic uterine leiomyoma. (Rader JS, Binette SP, Brandt TD, Sreekanth S, Chhablani A) Obstet Gynecol 1990 Sep;76(3 Pt 2):531-4 PMID 2381642
  • Radiation therapy in the treatment of cervical cancer: the University of Chicago/Michael Reese Hospital experience. (Rader JS, Haraf DJ, Halpern HJ, Rotmensch J, Spelbring DR, Sutton H, Javaheri G, Weichselbaum RR) J Surg Oncol 1990 Jul;44(3):157-65 PMID 2370799
  • In vitro differentiation of epithelial cells from cervical neoplasias resembles in vivo lesions. (Rader JS, Golub TR, Hudson JB, Patel D, Bedell MA, Laimins LA) Oncogene 1990 Apr;5(4):571-6 PMID 1691480
  • The mons pubis: an excellent graft donor site in gynecologic surgery. (Dudzinski MR, Rader JS) Am J Obstet Gynecol 1990 Mar;162(3):722-5 PMID 2316577
  • Grants and Awards

  • RECOVERY - The Cancer Genome Atlas Project - Cervical Cancer (#9206282 03/10/2010 - 09/30/2014) Sponsor: NIH Cancer Institute
  • The Cancer Genome Atlas (TCGA) Project (#9208477 11/18/2013 - 03/31/2014) Sponsor: Leidos Biomedical Research, Inc.
  • A Phase III Randomized Study of Exemestance Plus Placebo Versus Exemestane Plus Celecoxib Versus Placebo in Postmenopausal Women at Increased Risk of Developing Breast Cancer (#9303027 06/18/2004 - 12/30/2016) Sponsor: Queens University at Kingston
  • The Cancer Genome Atlas (TCGA) Project - SAIC-Frederick under primie contract with NCI (#9208213 09/01/2013 - 12/31/2013) Sponsor: SAIC-FREDERICK INC