Medical College of Wisconsin
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Jeffrey Kirsch MD

Vice Chair, Director, Professor

Institution: Medical College of Wisconsin
Department: Anesthesiology
Division: Clinical
Program: Operating Room Service


Publications (126)

  • Does Participation in Written Guided Reflective Practice Exercises Affect Readiness for Self-Directed Learning in a Sample of US Anesthesiology Residents? (Miller Juve AK, Kirsch JR) J Educ Perioper Med 2019 Apr-Jun;21(2):E622 PMID: 31988983 PMCID: PMC6972966 01/29/2020    
  • Oropharyngeal Oxygen Concentration Is Dependent on the Oxygen Mask System and Sampling Location. (Yanez ND, Fu AY, Treggiari MM, Kirsch JR) Respir Care 2020 Jan;65(1):29-35 PMID: 31506337 09/12/2019       1 Citation
  • Effects of anesthesia on cerebral blood flow, metabolism, and neuroprotection. (Slupe AM, Kirsch JR) J Cereb Blood Flow Metab 2018 12;38(12):2192-2208 PMID: 30009645 PMCID: PMC6282215 07/17/2018       20 Citations
  • Lean Strategies in the Operating Room. (Robinson ST, Kirsch JR) Anesthesiol Clin 2015 Dec;33(4):713-30 PMID: 26610625 11/28/2015       12 Citations
  • Erratum to: Assessing the Academic Productivity of Foundation for Anesthesia Education and Research (FAER) Resident Scholars. (Vega EA, Dillman D, Toledo P, Kirsch JR) J Educ Perioper Med 2015 Jul-Dec;17(4):E606 PMID: 28824933 PMCID: PMC5554703 07/01/2015    
  • Assessing the Academic Productivity of Foundation for Anesthesia Education and Research (FAER) Resident Scholars. (Vega EA, Dillman D, Toledo P, Kirsch JR) J Educ Perioper Med 2015 Jul-Dec;17(4):E302 PMID: 27957511 PMCID: PMC5131261 07/01/2015    
  • Future of anesthesiology is perioperative medicine: a call for action. (Kain ZN, Fitch JC, Kirsch JR, Mets B, Pearl RG) Anesthesiology 2015 Jun;122(6):1192-5 PMID: 25886775 04/19/2015       30 Citations
  • Caring for a patient with unexpected pheochromocytoma complicated by medical fraud. (Tully M, Trujillo J, Hou V, Kirsch J) A A Case Rep 2014 Mar 01;2(5):53-4 PMID: 25611364 01/23/2015    
  • Pre-operative management of the patient with chronic disease. (Brambrink AM, Rock P, Kirsch JR) Med Clin North Am 2013 Nov;97(6):xv-xvi PMID: 24182728 11/05/2013    
  • Barrier protection capacity of flip-top pharmaceutical vials. (Hilliard JG, Cambronne ED, Kirsch JR, Aziz MF) J Clin Anesth 2013 May;25(3):177-80 PMID: 23562539 04/09/2013       3 Citations
  • The practice of perioperative neuroanesthesiology. (Brambrink AM, Kirsch JR) Anesthesiol Clin 2012 Jun;30(2):xv-xvii PMID: 22901619 08/21/2012    
  • Anesthetic neurotoxicity. (Brambrink AM, Orfanakis A, Kirsch JR) Anesthesiol Clin 2012 Jun;30(2):207-28 PMID: 22901607 08/21/2012       31 Citations
  • Training intensivists and clinician-scientists for the 21st century: the Oregon scholars program. (Juve AM, Kirsch JR, Swide C) J Grad Med Educ 2010 Dec;2(4):585-8 PMID: 22132282 PMCID: PMC3010944 12/02/2011    
  • Local anesthetic Schwann cell toxicity is time and concentration dependent. (Yang S, Abrahams MS, Hurn PD, Grafe MR, Kirsch JR) Reg Anesth Pain Med 2011 Sep-Oct;36(5):444-51 PMID: 21857272 PMCID: PMC3380610 08/23/2011       64 Citations
  • Video laryngoscopy with the macintosh video laryngoscope in simulated prehospital scenarios by paramedic students. (Aziz M, Dillman D, Kirsch JR, Brambrink A) Prehosp Emerg Care 2009 Apr-Jun;13(2):251-5 PMID: 19291566 03/18/2009       28 Citations
  • Cyclic adenosine monophosphate response element-binding protein phosphorylation and neuroprotection by 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP). (Yang S, Alkayed NJ, Hurn PD, Kirsch JR) Anesth Analg 2009 Mar;108(3):964-70 PMID: 19224810 PMCID: PMC2828492 02/20/2009       15 Citations
  • Can gender differences be evaluated in a rhesus macaque (Macaca mulatta) model of focal cerebral ischemia? (Murphy SJ, Kirsch JR, Zhang W, Grafe MR, West GA, del Zoppo GJ, Traystman RJ, Hum PD) Comp Med 2008 Dec;58(6):588-96 PMID: 19149416 PMCID: PMC2629136 01/20/2009       10 Citations
  • Duty hours restriction and their effect on resident education and academic departments: the American perspective. (Swide CE, Kirsch JR) Curr Opin Anaesthesiol 2007 Dec;20(6):580-4 PMID: 17989554 11/09/2007       21 Citations
  • Perioperative care of patients with neuromuscular disease and dysfunction. (Brambrink AM, Kirsch JR) Anesthesiol Clin 2007 Sep;25(3):483-509, viii-ix PMID: 17884705 09/22/2007       15 Citations
  • Sigma receptor agonists provide neuroprotection in vitro by preserving bcl-2. (Yang S, Bhardwaj A, Cheng J, Alkayed NJ, Hurn PD, Kirsch JR) Anesth Analg 2007 May;104(5):1179-84, tables of contents PMID: 17456670 PMCID: PMC2596726 04/26/2007       59 Citations
  • Inhalational anesthetics as neuroprotectants or chemical preconditioning agents in ischemic brain. (Kitano H, Kirsch JR, Hurn PD, Murphy SJ) J Cereb Blood Flow Metab 2007 Jun;27(6):1108-28 PMID: 17047683 PMCID: PMC2266688 10/19/2006       144 Citations
  • Sigma 1 receptor agonists act as neuroprotective drugs through inhibition of inducible nitric oxide synthase. (Vagnerova K, Hurn PD, Bhardwaj A, Kirsch JR) Anesth Analg 2006 Aug;103(2):430-4, table of contents PMID: 16861428 07/25/2006       45 Citations
  • The efficacy of postoperative ondansetron (Zofran) orally disintegrating tablets for preventing nausea and vomiting after acoustic neuroma surgery. (Hartsell T, Long D, Kirsch JR) Anesth Analg 2005 Nov;101(5):1492-6 PMID: 16244017 10/26/2005       17 Citations
  • The efficacy of the arrow staple device for securing central venous catheters to human skin. (Motonaga GK, Lee KK, Kirsch JR) Anesth Analg 2004 Nov;99(5):1436-9; table of contents PMID: 15502044 10/27/2004       10 Citations
  • Strategies for prophylaxis and treatment for aspiration. (Kalinowski CP, Kirsch JR) Best Pract Res Clin Anaesthesiol 2004 Dec;18(4):719-37 PMID: 15460555 10/06/2004       54 Citations
  • Strategies of neuroprotection for intracranial aneurysms. (Frietsch T, Kirsch JR) Best Pract Res Clin Anaesthesiol 2004 Dec;18(4):595-630 PMID: 15460548 10/06/2004       6 Citations
  • Prolonged opportunity for ischemic neuroprotection with selective kappa-opioid receptor agonist in rats. (Chen TY, Goyagi T, Toung TJ, Kirsch JR, Hurn PD, Koehler RC, Bhardwaj A) Stroke 2004 May;35(5):1180-5 PMID: 15031456 03/20/2004       43 Citations
  • Kappa-opioid receptor selectivity for ischemic neuroprotection with BRL 52537 in rats. (Zhang Z, Chen TY, Kirsch JR, Toung TJ, Traystman RJ, Koehler RC, Hurn PD, Bhardwaj A) Anesth Analg 2003 Dec;97(6):1776-83 PMID: 14633559 11/25/2003       33 Citations
  • Cerebral resuscitation: role of osmotherapy. (Harukuni I, Kirsch JR, Bhardwaj A) J Anesth 2002;16(3):229-37 PMID: 14517646 10/01/2003    
  • Anesthetic implications of neuromuscular disease. (Briggs ED, Kirsch JR) J Anesth 2003;17(3):177-85 PMID: 12911205 08/13/2003       11 Citations
  • Critical care and perioperative management in traumatic spinal cord injury. (Stevens RD, Bhardwaj A, Kirsch JR, Mirski MA) J Neurosurg Anesthesiol 2003 Jul;15(3):215-29 PMID: 12826969 06/27/2003       76 Citations
  • Neuroprotective kappa-opioid receptor agonist BRL 52537 attenuates ischemia-evoked nitric oxide production in vivo in rats. (Goyagi T, Toung TJ, Kirsch JR, Traystman RJ, Koehler RC, Hurn PD, Bhardwaj A) Stroke 2003 Jun;34(6):1533-8 PMID: 12738895 05/10/2003       37 Citations
  • Mechanisms of ischemic brain damage. (Bhardwaj A, Alkayed NJ, Kirsch JR, Hurn PD) Curr Cardiol Rep 2003 Mar;5(2):160-7 PMID: 12583862 02/14/2003       31 Citations
  • Potent sigma 1-receptor ligand 4-phenyl-1-(4-phenylbutyl) piperidine provides ischemic neuroprotection without altering dopamine accumulation in vivo in rats. (Goyagi T, Bhardwaj A, Koehler RC, Traystman RJ, Hurn PD, Kirsch JR) Anesth Analg 2003 Feb;96(2):532-8, table of contents PMID: 12538208 01/23/2003       21 Citations
  • Anesthetic choice of halothane versus propofol: impact on experimental perioperative stroke. (Bhardwaj A, Castro III AF, Alkayed NJ, Hurn PD, Kirsch JR) Stroke 2001 Aug;32(8):1920-5 PMID: 11486126 08/04/2001       40 Citations
  • Neuroprotective effect of sigma(1)-receptor ligand 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP) is linked to reduced neuronal nitric oxide production. (Goyagi T, Goto S, Bhardwaj A, Dawson VL, Hurn PD, Kirsch JR) Stroke 2001 Jul;32(7):1613-20 PMID: 11441209 07/07/2001       73 Citations
  • Learning fiberoptic intubation on a simple model transfers to the O.R. (Naik V, Matsumoto E, Houston P, Hamstra S, Yeung R, Mallon J, Martire T, Zwack RM, Campbell DC, Breen TW, Yip RW, Roy JD, Girard M, Drolet P, Guay J, Bolis RS, LeDez K, Balatbat JT, Mukherji J, Ali MJ, Carroll J, Karski JM, Sui S, Cheng DC, Banner R, Yip R, Zondervan J, Chow V, McMillan D, Fisher J, Lattermann R, Carli F, Wykes L, Schricker T, Mazza L, Carli F, Danjoux G, Thomas D, Lennox PH, Henderson C, Martin L, Mitchell GW, Vaghadia H, Jassal R, Thomson IR, Hudson RJ, McGuire G, Manninen P, El-Beheiry H, Lozano A, Wennberg R, Archer DP, Tang TK, Staveley IR, Goldstein DH, VanDenKerkhof EG, Hall RI, Rocker GM, O'Connor JP, Dunham JI, Mikelberg FS, Dulovic G, Jenkins KL, Correa R, Wong DT, McGuire GP, Fayad AA, Paul J, Yang H, Sawchuk C, Brown KA, Bates JH, Edington R, Pridham J, Mukherji J, Karski JM, Balatbat J, Carroll J, Chun R, Cheng DC, Karski J, DeBrouwere R, Mathieu M, Carroll J, Feindel C, Cheng D, Clairoux M, Coutu S, McCluskey SA, Karkouti K, Ghannam M, Jewett M, Rampersaud R, Yau T, Quirt I, Carver ED, Kim P, Crawford MW, Finley GA, Breau LM, McGrath PJ, Camfield C, Mak PH, Hui TW, Irwin MG, Carli F, Trudel J, Belliveau P, Mayo N, Clunie ML, Crone LL, Klassen LJ, Yip RW, Hubert B, Radomski M, Blaise G, Renzi PM, Paradis MC, Martin R, Parent M, Parent P, Gagnon D, T├ętrault JP, Prabhu AJ, Philip BK, Higgins PP, Blanshard HJ, van Rensselaer S, Chung FF, Caraiscos VB, MacDonald JF, Orser BA, Schreiber M, Georgieff M, Jin F, Chung F, Tong D, Reiz JL, Harsanyi Z, Miceli PC, Darke AC, Roy JS, St-Pierre J, Norman PH, Daley MD, Turner KE, Parlow JL, Tod DA, Avery ND, Nicole PC, Tr├ępanier CA, Lessard MR, Marcoux S, Cowie DA, Gelb AW, Shoemaker JK, Baskett R, Lim BC, Dangor A, Morgan PJ, Cleave-Hogg D, Doyle DJ, Byrick R, Filipovi D, Cashin F, Chiu M, Kemp TJ, Bryson GL, Cleland MJ, Crosby ET, Harioka T, Nomura K, Ando N, Ikegami N, Aoki T, Maltby JR, Beriault MT, Watson NC, Liepert DJ, Fick GH, Maltby JR, Liepert D, Prabhu AJ, Correa RK, Wong DT, Chung F, Goyagi T, Bhardwaj A, Hum PD, Traystman RD, Kirsch JR, Bainbridge DT, Swaminathan M, McCreath BJ, Djaiani G, Grocott HP, Day F, Karski J, Djaiani G, Tan J, Cheng D, Wake PJ, Ali M, Karski J, Sui S, Guenther C, Mullen J, Bentley M, Koshal A, Finegan B, Murtha W, Fredrickson MJ, Luginbuehl IA, Bissonnette B, Granton JT, Platt H, Craen RA) Can J Anaesth 2001 Jun;48(Suppl 1):A2-A50 PMID: 27688127 06/01/2001    
  • sigma(1)-receptor ligand 4-phenyl-1-(4-phenylbutyl)-piperidine affords neuroprotection from focal ischemia with prolonged reperfusion. (Harukuni I, Bhardwaj A, Shaivitz AB, DeVries AC, London ED, Hurn PD, Traystman RJ, Kirsch JR, Faraci FM) Stroke 2000 Apr;31(4):976-82 PMID: 10754008 02/07/2001       45 Citations
  • Administration of selective endothelin receptor type A antagonist Ro 61-1790 does not improve outcome in focal cerebral ischemia in cat. (Bhardwaj A, Wu Y, Hurn PD, Kirsch JR, Traystman RJ) J Cereb Blood Flow Metab 2000 Mar;20(3):499-504 PMID: 10724114 03/21/2000       22 Citations
  • Antioxidant LY231617 enhances electrophysiologic recovery after global cerebral ischemia in dogs. (Toung TJ, Bhardwaj A, Wang M, Kirsch JR, Traystman RJ) Crit Care Med 2000 Jan;28(1):196-201 PMID: 10667522 02/10/2000       1 Citation
  • Oxotremorine-induced cerebral hyperemia does not predict infarction volume in spontaneously hypertensive or stroke-prone rats. (Harukuni I, Takahashi H, Traystman RJ, Bhardwaj A, Kirsch JR) Crit Care Med 2000 Jan;28(1):190-5 PMID: 10667521 02/10/2000       4 Citations
  • Effect of AR-R 17477, a potent neuronal nitric oxide synthase inhibitor, on infarction volume resulting from permanent focal ischemia in rats. (Harukuni I, Traystman RJ, Kirsch JR) Crit Care Med 1999 Nov;27(11):2508-11 PMID: 10579272 12/01/1999       17 Citations
  • Neuroprotection from focal ischemia by 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP) is dependent on treatment duration in rats. (Harukuni I, Bhardwaj A, Traystman RJ, Crain B, London ED, Kirsch JR) Anesth Analg 1998 Dec;87(6):1299-305 PMID: 9842816 12/08/1998       15 Citations
  • The effect of the prone position on pulmonary mechanics is frame-dependent. (Palmon SC, Kirsch JR, Depper JA, Toung TJ) Anesth Analg 1998 Nov;87(5):1175-80 PMID: 9806704 11/07/1998       54 Citations
  • Potent sigma1-receptor ligand 4-phenyl-1-(4-phenylbutyl) piperidine modulates basal and N-methyl-D-aspartate-evoked nitric oxide production in vivo. (Bhardwaj A, Sawada M, London ED, Koehler RC, Traystman RJ, Kirsch JR) Stroke 1998 Nov;29(11):2404-10; discussion 2411 PMID: 9804655 11/06/1998       38 Citations
  • Anesthetic agents and hypothermia in ischemic brain protection. (Bhardwaj A, Kirsch JR) Anesthesiology 1998 Aug;89(2):289-91 PMID: 9710385 08/26/1998       8 Citations
  • Intravenous basic fibroblast growth factor does not ameliorate brain injury resulting from transient focal ischemia in cats. (Harukuni I, Traystman RJ, Bhardwaj A, Koehler RC, Kirsch JR) J Neurosurg Anesthesiol 1998 Jul;10(3):160-5 PMID: 9681404 07/29/1998       3 Citations
  • Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: A perspective on the contributions of apoptosis and necrosis. (Martin LJ, Al-Abdulla NA, Brambrink AM, Kirsch JR, Sieber FE, Portera-Cailliau C) Brain Res Bull 1998 Jul 01;46(4):281-309 PMID: 9671259 07/22/1998       586 Citations
  • The effect of needle gauge and lidocaine pH on pain during intradermal injection. (Palmon SC, Lloyd AT, Kirsch JR) Anesth Analg 1998 Feb;86(2):379-81 PMID: 9459252 02/12/1998       83 Citations
  • Neither L-arginine nor L-NAME affects neurological outcome after global ischemia in cats. (Kirsch JR, Bhardwaj A, Martin LJ, Hanley DF, Traystman RJ) Stroke 1997 Nov;28(11):2259-64; discussion 2264-5 PMID: 9368574 11/22/1997       18 Citations
  • Postischemic brain injury is affected stereospecifically by pentazocine in rats. (Takahashi H, Traystman RJ, Hashimoto K, London ED, Kirsch JR) Anesth Analg 1997 Aug;85(2):353-7 PMID: 9249113 08/01/1997       20 Citations
  • Comparative analysis of brain protection by N-methyl-D-aspartate receptor antagonists after transient focal ischemia in cats. (Miyabe M, Kirsch JR, Nishikawa T, Koehler RC, Traystman RJ) Crit Care Med 1997 Jun;25(6):1037-43 PMID: 9201058 06/01/1997       14 Citations
  • Intravenous basic fibroblast growth factor decreases brain injury resulting from focal ischemia in cats. (Bethel A, Kirsch JR, Koehler RC, Finklestein SP, Traystman RJ) Stroke 1997 Mar;28(3):609-15; discussion 615-6 PMID: 9056620 03/01/1997       76 Citations
  • Intraventricular dexmedetomidine decreases cerebral blood flow during normoxia and hypoxia in dogs. (McPherson RW, Koehler RC, Kirsch JR, Traystman RJ) Anesth Analg 1997 Jan;84(1):139-47 PMID: 8989015 01/01/1997       29 Citations
  • PPBP [4-phenyl-1-(4-phenylbutyl) piperidine] decreases brain injury after transient focal ischemia in rats. (Takahashi H, Kirsch JR, Hashimoto K, London ED, Koehler RC, Traystman RJ) Stroke 1996 Nov;27(11):2120-3 PMID: 8898825 11/01/1996       49 Citations
  • Correlation of the average water diffusion constant with cerebral blood flow and ischemic damage after transient middle cerebral artery occlusion in cats. (Miyabe M, Mori S, van Zijl PC, Kirsch JR, Eleff SM, Koehler RC, Traystman RJ) J Cereb Blood Flow Metab 1996 Sep;16(5):881-91 PMID: 8784232 09/01/1996       69 Citations
  • Intensity of halothane- and hypercapnia-induced cerebral hyperemia is strain-dependent in rats. (Takahashi H, Kirsch JR, Okada T, Traystman RJ) Anesth Analg 1996 Aug;83(2):359-65 PMID: 8694319 08/01/1996       4 Citations
  • Capnography facilitates tight control of ventilation during transport. (Palmon SC, Liu M, Moore LE, Kirsch JR) Crit Care Med 1996 Apr;24(4):608-11 PMID: 8612411 04/01/1996       32 Citations
  • Treatment modalities for hypertensive patients with intracranial pathology: options and risks. (Tietjen CS, Hurn PD, Ulatowski JA, Kirsch JR) Crit Care Med 1996 Feb;24(2):311-22 PMID: 8605807 02/01/1996       80 Citations
  • Anesthetics and cerebroprotection: experimental aspects. (Kirsch JR, Traystman RJ, Hurn PD) Int Anesthesiol Clin 1996;34(4):73-93 PMID: 8956065 01/01/1996       27 Citations
  • Enhanced recovery of brain electrical activity by adenosine 3',5'-cyclic monophosphate following complete global cerebral ischemia in dogs. (Toung TJ, Kirsch JR, Traystman RJ) Crit Care Med 1996 Jan;24(1):103-8 PMID: 8565514 01/01/1996       5 Citations
  • Time-dependent inhibition of oxotremorine-induced cerebral hyperemia by N omega-nitro-L-arginine in cats. (Tietjen CS, Kirsch JR, Clavier N, Traystman RJ) Stroke 1995 Nov;26(11):2160-5 PMID: 7482666 11/01/1995       3 Citations
  • PPBP [4-phenyl-1-(4-phenylbutyl) piperidine], a potent sigma-receptor ligand, decreases brain injury after transient focal ischemia in cats. (Takahashi H, Kirsch JR, Hashimoto K, London ED, Koehler RC, Traystman RJ) Stroke 1995 Sep;26(9):1676-82 PMID: 7544928 09/01/1995       46 Citations
  • Postischemic cerebral blood flow recovery in the female: effect of 17 beta-estradiol. (Hurn PD, Littleton-Kearney MT, Kirsch JR, Dharmarajan AM, Traystman RJ) J Cereb Blood Flow Metab 1995 Jul;15(4):666-72 PMID: 7790416 07/01/1995       129 Citations
  • Effect of nitric oxide synthase inhibition on postischemic cerebral hyperemia. (Greenberg RS, Helfaer MA, Kirsch JR, Traystman RJ) Am J Physiol 1995 Jul;269(1 Pt 2):H341-7 PMID: 7543258 07/01/1995       27 Citations
  • Cerebral blood flow during inhibition of brain nitric oxide synthase activity in normal, hypertensive, and stroke-prone rats. (Izuta M, Clavier N, Kirsch JR, Traystman RJ) Stroke 1995 Jun;26(6):1079-85 PMID: 7539167 06/01/1995       22 Citations
  • Cerebral blood flow during cardiopulmonary bypass: influence of temperature and pH management strategy. (Cheng W, Hartmann JF, Cameron DE, Griffiths EM, Kirsch JR, Traystman RJ) Ann Thorac Surg 1995 Apr;59(4):880-6 PMID: 7695412 04/01/1995       16 Citations
  • Effect of nitric oxide synthase inhibition on the cerebral vascular response to hypercapnia in primates. (McPherson RW, Kirsch JR, Ghaly RF, Traystman RJ) Stroke 1995 Apr;26(4):682-7 PMID: 7535954 04/01/1995       53 Citations
  • Tirilazad pretreatment improves early cerebral metabolic and blood flow recovery from hyperglycemic ischemia. (Maruki Y, Koehler RC, Kirsch JR, Blizzard KK, Traystman RJ) J Cereb Blood Flow Metab 1995 Jan;15(1):88-96 PMID: 7798342 01/01/1995       21 Citations
  • Alpha 2-adrenergic agonist effects on normocapnic and hypercapnic cerebral blood flow in the dog are anesthetic dependent. (Fale A, Kirsch JR, McPherson RW) Anesth Analg 1994 Nov;79(5):892-8 PMID: 7978406 11/01/1994       32 Citations
  • Effect of postischemic hypoperfusion on vasodilatory mechanisms in cats. (Clavier N, Kirsch JR, Hurn PD, Traystman RJ) Am J Physiol 1994 Nov;267(5 Pt 2):H2012-8 PMID: 7977832 11/01/1994       34 Citations
  • Hypoxic reperfusion after ischemia in swine does not improve acute brain recovery. (Ulatowski JA, Kirsch JR, Traystman RJ) Am J Physiol 1994 Nov;267(5 Pt 2):H1880-7 PMID: 7977818 11/01/1994       10 Citations
  • Competitive N-methyl-D-aspartate receptor blockade reduces brain injury following transient focal ischemia in cats. (Nishikawa T, Kirsch JR, Koehler RC, Miyabe M, Traystman RJ) Stroke 1994 Nov;25(11):2258-64 PMID: 7526489 11/01/1994       25 Citations
  • Dihydropyridine ligand binding decreases earlier in adolescent than in infant swine after global cerebral ischemia. (Hoehner PJ, Kirsch JR, Helfaer MA, Ganunis TF, Murphy MT, Traystman RJ) Stroke 1994 Oct;25(10):2060-5; discussion 2066 PMID: 8091452 10/01/1994       5 Citations
  • Brain nitric oxide synthase activity in normal, hypertensive, and stroke-prone rats. (Clavier N, Tobin JR, Kirsch JR, Izuta M, Traystman RJ) Stroke 1994 Aug;25(8):1674-7; discussion 1677-8 PMID: 7518973 08/01/1994       28 Citations
  • Cerebral blood flow is reduced by N omega-nitro-L-arginine methyl ester during delayed hypoperfusion in cats. (Clavier N, Kirsch JR, Hurn PD, Traystman RJ) Am J Physiol 1994 Jul;267(1 Pt 2):H174-81 PMID: 8048583 07/01/1994       21 Citations
  • Nitric oxide and prostanoids contribute to isoflurane-induced cerebral hyperemia in pigs. (Moore LE, Kirsch JR, Helfaer MA, Tobin JR, McPherson RW, Traystman RJ) Anesthesiology 1994 Jun;80(6):1328-37 PMID: 7516628 06/01/1994       32 Citations
  • Cerebral blood flow in primates is increased by isoflurane over time and is decreased by nitric oxide synthase inhibition. (McPherson RW, Kirsch JR, Tobin JR, Ghaly RF, Traystman RJ) Anesthesiology 1994 Jun;80(6):1320-7 PMID: 7516627 06/01/1994       37 Citations
  • A cholinergic agonist induces cerebral hyperemia in isoflurane- but not pentobarbital-anesthetized dogs. (Sturaitis MK, Moore LE, Kirsch JR, McPherson RW) Anesth Analg 1994 May;78(5):876-83 PMID: 8160984 05/01/1994       8 Citations
  • Nitric oxide synthase inhibition reduces caudate injury following transient focal ischemia in cats. (Nishikawa T, Kirsch JR, Koehler RC, Miyabe M, Traystman RJ) Stroke 1994 Apr;25(4):877-85 PMID: 7512764 04/01/1994       51 Citations
  • Tirilazad treatment does not decrease early brain injury after transient focal ischemia in cats. (Takeshima R, Kirsch JR, Koehler RC, Traystman RJ) Stroke 1994 Mar;25(3):670-6 PMID: 8128524 03/01/1994       24 Citations
  • Nitric oxide synthase inhibition attenuates hypoglycemic cerebral hyperemia in piglets. (Ichord RN, Helfaer MA, Kirsch JR, Wilson D, Traystman RJ) Am J Physiol 1994 Mar;266(3 Pt 2):H1062-8 PMID: 7512794 03/01/1994       32 Citations
  • Nitric oxide synthase inhibition with NG-mono-methyl-L-arginine reversibly decreases cerebral blood flow in piglets. (Greenberg RS, Helfaer MA, Kirsch JR, Moore LE, Traystman RJ) Crit Care Med 1994 Mar;22(3):384-92 PMID: 7510221 03/01/1994       21 Citations
  • Effects of pentoxifylline on cerebral blood flow, metabolism, and evoked response after total cerebral ischemia in dogs. (Toung TJ, Kirsch JR, Maruki Y, Traystman RJ) Crit Care Med 1994 Feb;22(2):273-81 PMID: 8306687 02/01/1994       18 Citations
  • Reduced cerebral blood flow but intact reactivity to hypercarbia and hypoxia following subarachnoid hemorrhage in rabbits. (Diringer MN, Kirsch JR, Traystman RJ) J Cereb Blood Flow Metab 1994 Jan;14(1):59-63 PMID: 8263057 01/01/1994       12 Citations
  • Inhibition of nitric oxide synthase does not affect alpha 2-adrenergic-mediated cerebral vasoconstriction. (McPherson RW, Kirsch JR, Traystman RJ) Anesth Analg 1994 Jan;78(1):67-72 PMID: 7505532 01/01/1994       12 Citations
  • N omega-nitro-L-arginine methyl ester prevents cerebral hyperemia by inhaled anesthetics in dogs. (McPherson RW, Kirsch JR, Moore LE, Traystman RJ) Anesth Analg 1993 Nov;77(5):891-7 PMID: 8214724 11/01/1993       43 Citations
  • Effect of nitric oxide synthase inhibition on cerebral blood flow and injury volume during focal ischemia in cats. (Nishikawa T, Kirsch JR, Koehler RC, Bredt DS, Snyder SH, Traystman RJ) Stroke 1993 Nov;24(11):1717-24 PMID: 7694394 11/01/1993       107 Citations
  • Polyethylene glycol-conjugated superoxide dismutase improves recovery of postischemic hypercapnic cerebral blood flow in piglets. (Kirsch JR, Helfaer MA, Haun SE, Koehler RC, Traystman RJ) Pediatr Res 1993 Oct;34(4):530-7 PMID: 8255689 10/01/1993       17 Citations
  • Altered cerebrovascular CO2 reactivity following subarachnoid hemorrhage in cats. (Diringer MN, Kirsch JR, Hanley DF, Traystman RJ) J Neurosurg 1993 Jun;78(6):915-21 PMID: 8487074 06/01/1993       12 Citations
  • MK-801 does not prevent impaired cerebrovascular reactivity to CO2 during hypoglycemia in piglets. (St Jacques PJ, Kirsch JR, Diringer MN, Traystman RJ) Am J Physiol 1993 Jun;264(6 Pt 2):H2124-30 PMID: 8322942 06/01/1993       9 Citations
  • Effect of the 21-aminosteroid tirilazad on cerebral pH and somatosensory evoked potentials after incomplete ischemia. (Maruki Y, Koehler RC, Kirsch JR, Blizzard KK, Traystman RJ) Stroke 1993 May;24(5):724-30 PMID: 8488529 05/01/1993       28 Citations
  • Histamine-2-receptor blockade does not affect hyperemia after cerebral ischemia in young swine. (Tung WS, Helfaer MA, Kirsch JR, Traystman RJ) Crit Care Med 1993 Feb;21(2):260-6 PMID: 8428479 02/01/1993       3 Citations
  • Effect of intracarotid and intraventricular morphine on regional cerebral blood flow and metabolism in pentobarbital-anesthetized dogs. (Hoehner PJ, Whitson JT, Kirsch JR, Traystman RJ) Anesth Analg 1993 Feb;76(2):266-73 PMID: 8424502 02/01/1993       11 Citations
  • Tirilazad mesylate does not improve early cerebral metabolic recovery following compression ischemia in dogs. (Helfaer MA, Kirsch JR, Hurn PD, Blizzard KK, Koehler RC, Traystman RJ) Stroke 1992 Oct;23(10):1479-85; discussion 1485-6 PMID: 1412585 10/01/1992       16 Citations
  • Intra-arterial urokinase for treatment of retrograde thrombosis following resection of an arteriovenous malformation. Case report. (Sipos EP, Kirsch JR, Nauta HJ, Debrun G, Ulatowski JA, Bell WR) J Neurosurg 1992 Jun;76(6):1004-7 PMID: 1588404 06/01/1992       8 Citations
  • Hypercapnic blood flow reactivity not increased by alpha-blockade or cordotomy in piglets. (Moore LE, Kirsch JR, Helfaer MA, Greenberg RS, Traystman RJ) Am J Physiol 1992 Jun;262(6 Pt 2):H1884-90 PMID: 1352431 06/01/1992       7 Citations
  • Evidence for free radical mechanisms of brain injury resulting from ischemia/reperfusion-induced events. (Kirsch JR, Helfaer MA, Lange DG, Traystman RJ) J Neurotrauma 1992 Mar;9 Suppl 1:S157-63 PMID: 1588606 03/01/1992       42 Citations
  • Monoclonal leukocyte antibody does not decrease the injury of transient focal cerebral ischemia in cats. (Takeshima R, Kirsch JR, Koehler RC, Gomoll AW, Traystman RJ) Stroke 1992 Feb;23(2):247-52 PMID: 1561656 02/01/1992       56 Citations
  • Preoperative lumbar epidural morphine improves postoperative analgesia and ventilatory function after transsternal thymectomy in patients with myasthenia gravis. (Kirsch JR, Diringer MN, Borel CO, Hanley DF, Merritt WT, Bulkley GB) Crit Care Med 1991 Dec;19(12):1474-9 PMID: 1959365 12/01/1991       36 Citations
  • Oxygen radical mechanisms of brain injury following ischemia and reperfusion. (Traystman RJ, Kirsch JR, Koehler RC) J Appl Physiol (1985) 1991 Oct;71(4):1185-95 PMID: 1757340 10/01/1991       574 Citations
  • Hypothermic cerebral reperfusion and recovery from ischemia. (Baldwin WA, Kirsch JR, Hurn PD, Toung WS, Traystman RJ) Am J Physiol 1991 Sep;261(3 Pt 2):H774-81 PMID: 1909504 09/01/1991       36 Citations
  • Conjugated superoxide dismutase reduces extent of caudate injury after transient focal ischemia in cats. (Matsumiya N, Koehler RC, Kirsch JR, Traystman RJ) Stroke 1991 Sep;22(9):1193-200 PMID: 1718062 09/01/1991       68 Citations
  • Polyethylene glycol-conjugated superoxide dismutase fails to blunt postischemic reactive hyperemia. (Helfaer MA, Kirsch JR, Haun SE, Moore LE, Traystman RJ) Am J Physiol 1991 Aug;261(2 Pt 2):H548-53 PMID: 1877680 08/01/1991       17 Citations
  • Polyethylene glycol-conjugated superoxide dismutase fails to augment brain superoxide dismutase activity in piglets. (Haun SE, Kirsch JR, Helfaer MA, Kubos KL, Traystman RJ) Stroke 1991 May;22(5):655-9 PMID: 2028497 05/01/1991       34 Citations
  • Age-related differences in recovery of blood flow and metabolism after cerebral ischemia in swine. (Ichord RN, Kirsch JR, Helfaer MA, Haun S, Traystman RJ) Stroke 1991 May;22(5):626-34 PMID: 2028493 05/01/1991       24 Citations
  • Age-related cerebrovascular reactivity to CO2 after cerebral ischemia in swine. (Helfaer MA, Kirsch JR, Haun SE, Koehler RC, Traystman RJ) Am J Physiol 1991 May;260(5 Pt 2):H1482-8 PMID: 1903601 05/01/1991       22 Citations
  • Suprasellar and intraventricular blood predict elevated plasma atrial natriuretic factor in subarachnoid hemorrhage. (Diringer MN, Lim JS, Kirsch JR, Hanley DF) Stroke 1991 May;22(5):577-81 PMID: 1827548 05/01/1991       29 Citations
  • Cerebrovascular CO2 reactivity during delayed vasospasm in a canine model of subarachnoid hemorrhage. (Diringer MN, Heffez DS, Monsein L, Kirsch JR, Hanley DF, Traystman RJ) Stroke 1991 Mar;22(3):367-72 PMID: 1900646 SCOPUS ID: 2-s2.0-0025924557 03/01/1991       19 Citations
  • Age-related cerebrovascular response to global ischemia in pigs. (Kirsch JR, Helfaer MA, Blizzard K, Toung TJ, Traystman RJ) Am J Physiol 1990 Nov;259(5 Pt 2):H1551-8 PMID: 2240252 11/01/1990       25 Citations
  • Cerebrospinal fluid atrial natriuretic factor in intracranial disease. (Diringer MN, Kirsch JR, Ladenson PW, Borel C, Hanley DF) Stroke 1990 Nov;21(11):1550-4 PMID: 2146777 11/01/1990       10 Citations
  • Failure of endotoxic shock to elicit superoxide anion production in pig brain. (Deutschman CS, Kirsch JR, Breslow MJ, Miller CF, Traystman RJ) Circ Shock 1990 Jun;31(2):149-58 PMID: 2160865 06/01/1990       4 Citations
  • Anesthetic modulation of cerebral hemodynamic and evoked responses to transient middle cerebral artery occlusion in cats. (Helfaer MA, Kirsch JR, Traystman RJ) Stroke 1990 May;21(5):795-800 PMID: 2339460 05/01/1990       20 Citations
  • Cerebral aneurysms: mechanisms of injury and critical care interventions. (Kirsch JR, Diringer MN, Borel CO, Hanley DF) Crit Care Clin 1989 Oct;5(4):755-72 PMID: 2676097 10/01/1989       4 Citations
  • Sodium and water regulation in a patient with cerebral salt wasting. (Diringer M, Ladenson PW, Borel C, Hart GK, Kirsch JR, Hanley DF) Arch Neurol 1989 Aug;46(8):928-30 PMID: 2757534 08/01/1989       42 Citations
  • Current concepts in brain resuscitation. (Rogers MC, Kirsch JR) JAMA 1989 Jun 02;261(21):3143-7 PMID: 2565985 06/02/1989       17 Citations
  • Brain resuscitation. Medical management and innovations. (Kirsch JR, Diringer MN, Borel CO, Hart GK, Hanley DF Jr) Crit Care Nurs Clin North Am 1989 Mar;1(1):143-54 PMID: 2679786 03/01/1989       5 Citations
  • Effect of centrally administered encephalinamides on regional cerebral blood flow in the dog. (Kirsch JR, Hanley DF, Wilson DA, Traystman RJ) J Cereb Blood Flow Metab 1988 Jun;8(3):385-94 PMID: 3366800 06/01/1988       9 Citations
  • Current concepts in brain resuscitation. (Kirsch JR, Dean JM, Rogers MC) Arch Intern Med 1986 Jul;146(7):1413-9 PMID: 3521528 07/01/1986       12 Citations
  • Cerebral blood flow measurement techniques in infants and children. (Kirsch JR, Traystman RJ, Rogers MC) Pediatrics 1985 May;75(5):887-95 PMID: 3157917 05/01/1985       10 Citations
  • Glucagon stimulates ketone utilization by rat brain slices. (Kirsch JR, D'Alecy LG) Stroke 1984 Mar-Apr;15(2):324-8 PMID: 6422589 03/01/1984       14 Citations
  • Hypoxia induced preferential ketone utilization by rat brain slices. (Kirsch JR, D'Alecy LG) Stroke 1984 Mar-Apr;15(2):319-23 PMID: 6422588 03/01/1984       27 Citations
  • Role of tissue lactate and substrate availability in 1,3-butanediol-enhanced hypoxic survival in the mouse. (Kirsch JR, D'Alecy LG) Stroke 1983 Nov-Dec;14(6):971-6 PMID: 6362095 11/01/1983       12 Citations
  • Hypoxic tolerance enhanced by beta-hydroxybutyrate-glucagon in the mouse. (Eiger SM, Kirsch JR, D'Alecy LG) Stroke 1980 Sep-Oct;11(5):513-7 PMID: 6775395 09/01/1980       24 Citations
  • Butanediol induced ketosis increases tolerance to hypoxia in the mouse. (Kirsch JR, D'Alecy LG, Mongroo PB) Stroke 1980 Sep-Oct;11(5):506-13 PMID: 6775394 09/01/1980       29 Citations
  • Effect of altered availability of energy-yielding substrates upon survival from hypoxia in mice. (Kirsch JR, D'Alecy LG) Stroke 1979 May-Jun;10(3):288-91 PMID: 462515 05/01/1979       37 Citations
  • Last update: 08/26/2020
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