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Jennifer A. Doll PhD

Jennifer A. Doll PhD

Assistant Professor

Institution: University of Wisconsin - Milwaukee
Department: Biomedical Sciences

Member of the Cancer Center


  • Periprostatic adipose tissue from obese prostate cancer patients promotes tumor and endothelial cell proliferation: a functional and MR imaging pilot study. (Venkatasubramanian PN, Brendler CB, Plunkett BA, Crawford SE, Fitchev PS, Morgan G, Cornwell ML, McGuire MS, Wyrwicz AM, Doll JA) Prostate 2014 Feb;74(3):326-35 PMID: 24571013
  • Mutations in SERPINF1 cause osteogenesis imperfecta type VI. (Homan EP, Rauch F, Grafe I, Lietman C, Doll JA, Dawson B, Bertin T, Napierala D, Morello R, Gibbs R, White L, Miki R, Cohn DH, Crawford S, Travers R, Glorieux FH, Lee B) J Bone Miner Res 2011 Dec;26(12):2798-803 PMID: 21826736 PMCID: PMC3214246
  • Overexpression of transforming growth factor β1 in malignant prostate cells is partly caused by a runaway of TGF-β1 auto-induction mediated through a defective recruitment of protein phosphatase 2A by TGF-β type I receptor. (Yu N, Kozlowski JM, Park II, Chen L, Zhang Q, Xu D, Doll JA, Crawford SE, Brendler CB, Lee C) Urology 2010 Dec;76(6):1519.e8-13 PMID: 21030067 PMCID: PMC2997920
  • Thrombospondin-1 regulates the normal prostate in vivo through angiogenesis and TGF-beta activation. (Fitchev PP, Wcislak SM, Lee C, Bergh A, Brendler CB, Stellmach VM, Crawford SE, Mavroudis CD, Cornwell ML, Doll JA) Lab Invest 2010 Jul;90(7):1078-90 PMID: 20458281 PMCID: PMC3055786
  • Pigment epithelium-derived factor stimulates tumor macrophage recruitment and is downregulated by the prostate tumor microenvironment. (Halin S, Rudolfsson SH, Doll JA, Crawford SE, Wikström P, Bergh A) Neoplasia 2010 Apr;12(4):336-45 PMID: 20360944 PMCID: PMC2847741
  • Ethanol exposure depletes hepatic pigment epithelium-derived factor, a novel lipid regulator. (Chung C, Shugrue C, Nagar A, Doll JA, Cornwell M, Gattu A, Kolodecik T, Pandol SJ, Gorelick F) Gastroenterology 2009 Jan;136(1):331-340.e2 PMID: 18996124 PMCID: PMC2833423
  • Decreased expression of pigment epithelium derived factor (PEDF), an inhibitor of angiogenesis, in placentas of unexplained stillbirths. (Plunkett BA, Fitchev P, Doll JA, Gerber SE, Cornwell M, Greenstein EP, Crawford SE) Reprod Biol 2008 Jul;8(2):107-20 PMID: 18677399
  • Pigment epithelium-derived factor is an angiogenesis and lipid regulator that activates peroxisome proliferator-activated receptor alpha. (Chung C, Doll JA, Stellmach VM, Gonzales J, Surapureddi S, Cornwell M, Reddy JK, Crawford SE) Adv Exp Med Biol 2008;617:591-7 PMID: 18497086
  • Anti-angiogenic pigment epithelium-derived factor regulates hepatocyte triglyceride content through adipose triglyceride lipase (ATGL). (Chung C, Doll JA, Gattu AK, Shugrue C, Cornwell M, Fitchev P, Crawford SE) J Hepatol 2008 Mar;48(3):471-8 PMID: 18191271
  • Alternatively spliced human tissue factor promotes tumor growth and angiogenesis in a pancreatic cancer tumor model. (Hobbs JE, Zakarija A, Cundiff DL, Doll JA, Hymen E, Cornwell M, Crawford SE, Liu N, Signaevsky M, Soff GA) Thromb Res 2007;120 Suppl 2:S13-21 PMID: 18023707
  • Gene transfer of pigment epithelium-derived factor suppresses tumor growth and angiogenesis in a hepatoblastoma xenograft model. (Browne M, Stellmach V, Cornwell M, Chung C, Doll JA, Lee EJ, Jameson JL, Reynolds M, Superina RA, Abramson LP, Crawford SE) Pediatr Res 2006 Sep;60(3):282-7 PMID: 16857775
  • Differential binding of plasminogen, plasmin, and angiostatin4.5 to cell surface beta-actin: implications for cancer-mediated angiogenesis. (Wang H, Doll JA, Jiang K, Cundiff DL, Czarnecki JS, Wilson M, Ridge KM, Soff GA) Cancer Res 2006 Jul 15;66(14):7211-5 PMID: 16849568
  • Angiostatin. (Doll JA, Soff GA) Cancer Treat Res 2005;126:175-204 PMID: 16209067
  • In vivo generation of angiostatin isoforms by administration of a plasminogen activator and a free sulfhydryl donor: a phase I study of an angiostatic cocktail of tissue plasminogen activator and mesna. (Soff GA, Wang H, Cundiff DL, Jiang K, Martone B, Rademaker AW, Doll JA, Kuzel TM) Clin Cancer Res 2005 Sep 1;11(17):6218-25 PMID: 16144924
  • Decreased pigment epithelium-derived factor is associated with metastatic phenotype in human and rat prostate tumors. (Halin S, Wikström P, Rudolfsson SH, Stattin P, Doll JA, Crawford SE, Bergh A) Cancer Res 2004 Aug 15;64(16):5664-71 PMID: 15313905
  • Cardiac plasma cell granulomas: response to oral steroid treatment. (Ferbend P, Abramson LP, Backer CL, Mavroudis C, Webb CL, Doll JA, Junewick JJ, Crawford SE) Pediatr Cardiol 2004 Jul-Aug;25(4):406-10 PMID: 15054564
  • Pigment epithelium-derived factor, a human testis epididymis secretory product, promotes human prostate stromal cell growth in culture. (Grayhack JT, Smith ND, Ilio K, Wambi C, Kasjanski R, Crawford SE, Doll JA, Wang Z, Lee C, Kozlowski JM) J Urol 2004 Jan;171(1):434-8 PMID: 14665949
  • Pigment epithelium-derived factor regulates the vasculature and mass of the prostate and pancreas. (Doll JA, Stellmach VM, Bouck NP, Bergh AR, Lee C, Abramson LP, Cornwell ML, Pins MR, Borensztajn J, Crawford SE) Nat Med 2003 Jun;9(6):774-80 PMID: 12740569
  • Wilms' tumor growth is suppressed by antiangiogenic pigment epithelium-derived factor in a xenograft model. (Abramson LP, Stellmach V, Doll JA, Cornwell M, Arensman RM, Crawford SE) J Pediatr Surg 2003 Mar;38(3):336-42; discussion 336-42 PMID: 12632345
  • Thrombospondin-1, vascular endothelial growth factor and fibroblast growth factor-2 are key functional regulators of angiogenesis in the prostate. (Doll JA, Reiher FK, Crawford SE, Pins MR, Campbell SC, Bouck NP) Prostate 2001 Dec 1;49(4):293-305 PMID: 11746276
  • Genetic analysis of prostatic atypical adenomatous hyperplasia (adenosis). (Doll JA, Zhu X, Furman J, Kaleem Z, Torres C, Humphrey PA, Donis-Keller H) Am J Pathol 1999 Sep;155(3):967-71 PMID: 10487854 PMCID: PMC1866890
  • Association between prostate cancer in black Americans and an allele of the PADPRP pseudogene locus on chromosome 13. (Doll JA, Suarez BK, Donis-Keller H) Am J Hum Genet 1996 Feb;58(2):425-8 PMID: 8571971 PMCID: PMC1914538
  • Last update: 09/03/2013