Medical College of Wisconsin
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John E. Baker PhD

John E. Baker PhD


Institution: Medical College of Wisconsin
Department: Surgery
Division: Pediatric Congenital Cardiac Surgery
Program: Research - Dr. Baker

Member of the Cancer Center
Member of the Cardiovascular Center

Research Experience

  • Cardiovascular Agents
  • Cardiovascular Diseases
  • Cardiovascular Physiological Phenomena
  • Cardiovascular System
  • Radiation Effects
  • Radiation Genetics
  • Radiation Injuries
  • Radiation Injuries, Experimental
  • Radiation Tolerance
  • Radiation, Ionizing
  • Radiation-Protective Agents
  • radiation effects
  • Microbiota
  • Clinical Expertise

  • Clinical Trial
  • Clinical Trials, Phase II as Topic
  • Drugs, Investigational
  • Leadership Positions

  • Chair, Institutional Animal Care and Use Committee
  • Publications

  • Lactobacillus plantarum 299v Supplementation Improves Vascular Endothelial Function and Reduces Inflammatory Biomarkers in Men With Stable Coronary Artery Disease. (Malik M, Suboc TM, Tyagi S, Salzman N, Wang J, Ying R, Tanner MJ, Kakarla M, Baker JE, Widlansky ME) Circ Res 2018 Oct 12;123(9):1091-1102 PMID: 30355158 PMCID: PMC6205737 10/26/2018    
  • Radiation-induced changes in intestinal and tissue-nonspecific alkaline phosphatase: implications for recovery after radiation therapy. (Rentea RM, Lam V, Biesterveld B, Fredrich KM, Callison J, Fish BL, Baker JE, Komorowski R, Gourlay DM, Otterson MF) Am J Surg 2016 Oct;212(4):602-608 PMID: 27501776 08/10/2016       1 Citations
  • Intestinal Microbial Metabolites Are Linked to Severity of Myocardial Infarction in Rats. (Lam V, Su J, Hsu A, Gross GJ, Salzman NH, Baker JE) PLoS One 2016;11(8):e0160840 PMID: 27505423 PMCID: PMC4978455 08/10/2016       16 Citations
  • Simvastatin mitigates increases in risk factors for and the occurrence of cardiac disease following 10 Gy total body irradiation. (Lenarczyk M, Su J, Haworth ST, Komorowski R, Fish BL, Migrino RQ, Harmann L, Hopewell JW, Kronenberg A, Patel S, Moulder JE, Baker JE) Pharmacol Res Perspect 2015 Jun;3(3):e00145 PMID: 26171225 PMCID: PMC4492761 07/15/2015    
  • Thrombopoietin receptor agonists protect human cardiac myocytes from injury by activation of cell survival pathways. (Baker JE, Su J, Koprowski S, Dhanasekaran A, Aufderheide TP, Gross GJ) J Pharmacol Exp Ther 2015 Mar;352(3):429-37 PMID: 25512369 12/17/2014       5 Citations
  • Erythropoietin protects cardiomyocytes from cell death during hypoxia/reperfusion injury through activation of survival signaling pathways. (Parvin A, Pranap R, Shalini U, Devendran A, Baker JE, Dhanasekaran A) PLoS One 2014;9(9):e107453 PMID: 25237819 PMCID: PMC4169563 09/23/2014       12 Citations
  • Cardioprotection from ischemia-reperfusion injury by near-infrared light in rats. (Quirk BJ, Sonowal P, Jazayeri MA, Baker JE, Whelan HT) Photomed Laser Surg 2014 Sep;32(9):505-11 PMID: 25093393 PMCID: PMC4142831 08/06/2014       4 Citations
  • Safety and blood sample volume and quality of a refined retro-orbital bleeding technique in rats using a lateral approach. (Sharma A, Fish BL, Moulder JE, Medhora M, Baker JE, Mader M, Cohen EP) Lab Anim (NY) 2014 Feb;43(2):63-6 PMID: 24451361 PMCID: PMC3989930 01/24/2014       12 Citations
  • Cardiac injury after 10 gy total body irradiation: indirect role of effects on abdominal organs. (Lenarczyk M, Lam V, Jensen E, Fish BL, Su J, Koprowski S, Komorowski RA, Harmann L, Migrino RQ, Li XA, Hopewell JW, Moulder JE, Baker JE) Radiat Res 2013 Sep;180(3):247-58 PMID: 23919311 PMCID: PMC4042860 08/08/2013       23 Citations
  • Heparin oligosaccharides inhibit chemokine (CXC motif) ligand 12 (CXCL12) cardioprotection by binding orthogonal to the dimerization interface, promoting oligomerization, and competing with the chemokine (CXC motif) receptor 4 (CXCR4) N terminus. (Ziarek JJ, Veldkamp CT, Zhang F, Murray NJ, Kartz GA, Liang X, Su J, Baker JE, Linhardt RJ, Volkman BF) J Biol Chem 2013 Jan 04;288(1):737-46 PMID: 23148226 PMCID: PMC3537072 11/14/2012       42 Citations
  • Response. (Lam V, Su J, Koprowski S, Hsu A, Tweddell JS, Rafiee P, Gross GJ, Salzman NH, Baker JE) FASEB J 2012 Nov;26(11):4388-9 PMID: 23118151 11/03/2012    
  • Intestinal microbiota as novel biomarkers of prior radiation exposure. (Lam V, Moulder JE, Salzman NH, Dubinsky EA, Andersen GL, Baker JE) Radiat Res 2012 May;177(5):573-83 PMID: 22439602 03/24/2012       25 Citations
  • Intestinal microbiota determine severity of myocardial infarction in rats. (Lam V, Su J, Koprowski S, Hsu A, Tweddell JS, Rafiee P, Gross GJ, Salzman NH, Baker JE) FASEB J 2012 Apr;26(4):1727-35 PMID: 22247331 PMCID: PMC3316900 01/17/2012       89 Citations
  • Laminin 332 deposition is diminished in irradiated skin in an animal model of combined radiation and wound skin injury. (Jourdan MM, Lopez A, Olasz EB, Duncan NE, Demara M, Kittipongdaja W, Fish BL, Mäder M, Schock A, Morrow NV, Semenenko VA, Baker JE, Moulder JE, Lazarova Z) Radiat Res 2011 Nov;176(5):636-48 PMID: 21854211 PMCID: PMC3227557 08/23/2011       12 Citations
  • Abdominal surgical incision induces remote preconditioning of trauma (RPCT) via activation of bradykinin receptors (BK2R) and the cytochrome P450 epoxygenase pathway in canine hearts. (Gross GJ, Baker JE, Moore J, Falck JR, Nithipatikom K) Cardiovasc Drugs Ther 2011 Dec;25(6):517-22 PMID: 21786213 PMCID: PMC3329256 07/26/2011       42 Citations
  • Radiation as a risk factor for cardiovascular disease. (Baker JE, Moulder JE, Hopewell JW) Antioxid Redox Signal 2011 Oct 01;15(7):1945-56 PMID: 21091078 PMCID: PMC3159113 11/26/2010       54 Citations
  • Evidence for a role of opioids in epoxyeicosatrienoic acid-induced cardioprotection in rat hearts. (Gross GJ, Baker JE, Hsu A, Wu HE, Falck JR, Nithipatikom K) Am J Physiol Heart Circ Physiol 2010 Jun;298(6):H2201-7 PMID: 20400686 PMCID: PMC2886625 04/20/2010       27 Citations
  • Gadolinium decreases inflammation related to myocardial ischemia and reperfusion injury. (Strande JL, Routhu KV, Hsu A, Nicolosi AC, Baker JE) J Inflamm (Lond) 2009 Dec 10;6:34 PMID: 20003243 PMCID: PMC2799407 12/17/2009    
  • 10 Gy total body irradiation increases risk of coronary sclerosis, degeneration of heart structure and function in a rat model. (Baker JE, Fish BL, Su J, Haworth ST, Strande JL, Komorowski RA, Migrino RQ, Doppalapudi A, Harmann L, Allen Li X, Hopewell JW, Moulder JE) Int J Radiat Biol 2009 Dec;85(12):1089-100 PMID: 19995235 PMCID: PMC2792125 12/10/2009       56 Citations
  • Monomeric structure of the cardioprotective chemokine SDF-1/CXCL12. (Veldkamp CT, Ziarek JJ, Su J, Basnet H, Lennertz R, Weiner JJ, Peterson FC, Baker JE, Volkman BF) Protein Sci 2009 Jul;18(7):1359-69 PMID: 19551879 PMCID: PMC2775206 06/25/2009       56 Citations
  • Parstatin: a cryptic peptide involved in cardioprotection after ischaemia and reperfusion injury. (Strande JL, Widlansky ME, Tsopanoglou NE, Su J, Wang J, Hsu A, Routhu KV, Baker JE) Cardiovasc Res 2009 Jul 15;83(2):325-34 PMID: 19380418 PMCID: PMC2701720 04/22/2009       17 Citations
  • Chronic hypoxia enhances 15-lipoxygenase-mediated vasorelaxation in rabbit arteries. (Aggarwal NT, Pfister SL, Gauthier KM, Chawengsub Y, Baker JE, Campbell WB) Am J Physiol Heart Circ Physiol 2009 Mar;296(3):H678-88 PMID: 19112096 PMCID: PMC2660232 12/30/2008       11 Citations
  • Gadolinium limits myocardial infarction in the rat: dose-response, temporal relations and mechanisms. (Nicolosi AC, Strande JL, Hsu A, Fu X, Su J, Gross GJ, Baker JE) J Mol Cell Cardiol 2008 Feb;44(2):345-51 PMID: 18083188 PMCID: PMC2322938 12/18/2007       9 Citations
  • Inhibiting protease-activated receptor 4 limits myocardial ischemia/reperfusion injury in rat hearts by unmasking adenosine signaling. (Strande JL, Hsu A, Su J, Fu X, Gross GJ, Baker JE) J Pharmacol Exp Ther 2008 Mar;324(3):1045-54 PMID: 18055876 PMCID: PMC2935083 12/07/2007       37 Citations
  • Mitochondrial big conductance KCa channel and cardioprotection in infant rabbit heart. (Shi Y, Jiang MT, Su J, Hutchins W, Konorev E, Baker JE) J Cardiovasc Pharmacol 2007 Nov;50(5):497-502 PMID: 18030058 11/22/2007       18 Citations
  • Human thrombopoietin reduces myocardial infarct size, apoptosis, and stunning following ischaemia/reperfusion in rats. (Baker JE, Su J, Hsu A, Shi Y, Zhao M, Strande JL, Fu X, Xu H, Eis A, Komorowski R, Jensen ES, Tweddell JS, Rafiee P, Gross GJ) Cardiovasc Res 2008 Jan;77(1):44-53 PMID: 18006466 PMCID: PMC2958050 11/17/2007       29 Citations
  • Nitrite confers protection against myocardial infarction: role of xanthine oxidoreductase, NADPH oxidase and K(ATP) channels. (Baker JE, Su J, Fu X, Hsu A, Gross GJ, Tweddell JS, Hogg N) J Mol Cell Cardiol 2007 Oct;43(4):437-44 PMID: 17765919 PMCID: PMC2735077 09/04/2007       99 Citations
  • Darbepoetin alfa protects the rat heart against infarction: dose-response, phase of action, and mechanisms. (Baker JE, Kozik D, Hsu AK, Fu X, Tweddell JS, Gross GJ) J Cardiovasc Pharmacol 2007 Jun;49(6):337-45 PMID: 17577097 06/20/2007       39 Citations
  • SCH 79797, a selective PAR1 antagonist, limits myocardial ischemia/reperfusion injury in rat hearts. (Strande JL, Hsu A, Su J, Fu X, Gross GJ, Baker JE) Basic Res Cardiol 2007 Jul;102(4):350-8 PMID: 17468933 PMCID: PMC3942648 05/01/2007       73 Citations
  • Hyperoxic and hyperbaric-induced cardioprotection: role of nitric oxide synthase 3. (Cabigas BP, Su J, Hutchins W, Shi Y, Schaefer RB, Recinos RF, Nilakantan V, Kindwall E, Niezgoda JA, Baker JE) Cardiovasc Res 2006 Oct 01;72(1):143-51 PMID: 16930572 08/26/2006       49 Citations
  • Antagonizing reactive oxygen by treatment with a manganese (III) metalloporphyrin-based superoxide dismutase mimetic in cardiac transplants. (Nilakantan V, Zhou X, Hilton G, Shi Y, Baker JE, Khanna AK, Pieper GM) J Thorac Cardiovasc Surg 2006 Apr;131(4):898-906 PMID: 16580450 04/04/2006       17 Citations
  • BN phenome: detailed characterization of the cardiovascular, renal, and pulmonary systems of the sequenced rat. (Kwitek AE, Jacob HJ, Baker JE, Dwinell MR, Forster HV, Greene AS, Kunert MP, Lombard JH, Mattson DL, Pritchard KA Jr, Roman RJ, Tonellato PJ, Cowley AW Jr) Physiol Genomics 2006 Apr 13;25(2):303-13 PMID: 16478827 02/16/2006       26 Citations
  • Erythropoietin mimics ischemic preconditioning. (Baker JE) Vascul Pharmacol 2005 Apr-May;42(5-6):233-41 PMID: 15922256 06/01/2005       60 Citations
  • Increased resistance to myocardial ischemia in the Brown Norway vs. Dahl S rat: role of nitric oxide synthase and Hsp90. (Shi Y, Hutchins W, Ogawa H, Chang CC, Pritchard KA Jr, Zhang C, Khampang P, Lazar J, Jacob HJ, Rafiee P, Baker JE) J Mol Cell Cardiol 2005 Apr;38(4):625-35 PMID: 15808839 04/06/2005       29 Citations
  • Erythropoietin protects the infant heart against ischemia-reperfusion injury by triggering multiple signaling pathways. (Rafiee P, Shi Y, Su J, Pritchard KA Jr, Tweddell JS, Baker JE) Basic Res Cardiol 2005 May;100(3):187-97 PMID: 15611843 12/22/2004       92 Citations
  • Delayed cardioprotection with isoflurane: role of reactive oxygen and nitrogen. (Shi Y, Hutchins WC, Su J, Siker D, Hogg N, Pritchard KA Jr, Keszler A, Tweddell JS, Baker JE) Am J Physiol Heart Circ Physiol 2005 Jan;288(1):H175-84 PMID: 15388508 09/25/2004       34 Citations
  • Cardioprotection in chronically hypoxic rabbits persists on exposure to normoxia: role of NOS and KATP channels. (Fitzpatrick CM, Shi Y, Hutchins WC, Su J, Gross GJ, Ostadal B, Tweddell JS, Baker JE) Am J Physiol Heart Circ Physiol 2005 Jan;288(1):H62-8 PMID: 15319200 08/21/2004       40 Citations
  • Acute cardioprotective effects of erythropoietin in infant rabbits are mediated by activation of protein kinases and potassium channels. (Shi Y, Rafiee P, Su J, Pritchard KA Jr, Tweddell JS, Baker JE) Basic Res Cardiol 2004 May;99(3):173-82 PMID: 15088102 04/17/2004       76 Citations
  • Oxidative stress and adaptation of the infant heart to hypoxia and ischemia. (Baker JE) Antioxid Redox Signal 2004 Apr;6(2):423-9 PMID: 15025944 03/18/2004       29 Citations
  • Cellular redistribution of inducible Hsp70 protein in the human and rabbit heart in response to the stress of chronic hypoxia: role of protein kinases,. (Rafiee P, Shi Y, Pritchard KA Jr, Ogawa H, Eis AL, Komorowski RA, Fitzpatrick CM, Tweddell JS, Litwin SB, Mussatto K, Jaquiss RD, Baker JE) J Biol Chem 2003 Oct 31;278(44):43636-44 PMID: 12937165 08/26/2003       44 Citations
  • Chronic hypoxia activates lung 15-lipoxygenase, which catalyzes production of 15-HETE and enhances constriction in neonatal rabbit pulmonary arteries. (Zhu D, Medhora M, Campbell WB, Spitzbarth N, Baker JE, Jacobs ER) Circ Res 2003 May 16;92(9):992-1000 PMID: 12690037 04/12/2003       125 Citations
  • Chronic hypoxia increases endothelial nitric oxide synthase generation of nitric oxide by increasing heat shock protein 90 association and serine phosphorylation. (Shi Y, Baker JE, Zhang C, Tweddell JS, Su J, Pritchard KA Jr) Circ Res 2002 Aug 23;91(4):300-6 PMID: 12193462 08/24/2002       85 Citations
  • Activation of protein kinases in chronically hypoxic infant human and rabbit hearts: role in cardioprotection. (Rafiee P, Shi Y, Kong X, Pritchard KA Jr, Tweddell JS, Litwin SB, Mussatto K, Jaquiss RD, Su J, Baker JE) Circulation 2002 Jul 09;106(2):239-45 PMID: 12105165 07/10/2002       69 Citations
  • Delayed cardioprotection by isoflurane: role of K(ATP) channels. (Tonkovic-Capin M, Gross GJ, Bosnjak ZJ, Tweddell JS, Fitzpatrick CM, Baker JE) Am J Physiol Heart Circ Physiol 2002 Jul;283(1):H61-8 PMID: 12063275 06/14/2002       79 Citations
  • Sarcolemmal and mitochondrial K(atp)channels mediate cardioprotection in chronically hypoxic hearts. (Kong X, Tweddell JS, Gross GJ, Baker JE) J Mol Cell Cardiol 2001 May;33(5):1041-5 PMID: 11343425 05/10/2001       31 Citations
  • Heat shock protein 90 mediates the balance of nitric oxide and superoxide anion from endothelial nitric-oxide synthase. (Pritchard KA Jr, Ackerman AW, Gross ER, Stepp DW, Shi Y, Fontana JT, Baker JE, Sessa WC) J Biol Chem 2001 May 25;276(21):17621-4 PMID: 11278264 03/30/2001       253 Citations
  • Nitric oxide activates the sarcolemmal K(ATP) channel in normoxic and chronically hypoxic hearts by a cyclic GMP-dependent mechanism. (Baker JE, Contney SJ, Singh R, Kalyanaraman B, Gross GJ, Bosnjak ZJ) J Mol Cell Cardiol 2001 Feb;33(2):331-41 PMID: 11162137 02/13/2001       37 Citations
  • Increased mitochondrial K(ATP) channel activity during chronic myocardial hypoxia: is cardioprotection mediated by improved bioenergetics? (Eells JT, Henry MM, Gross GJ, Baker JE) Circ Res 2000 Nov 10;87(10):915-21 PMID: 11073888 11/14/2000       57 Citations
  • Chronic myocardial hypoxia increases nitric oxide synthase and decreases caveolin-3. (Shi Y, Pritchard KA Jr, Holman P, Rafiee P, Griffith OW, Kalyanaraman B, Baker JE) Free Radic Biol Med 2000 Oct 15;29(8):695-703 PMID: 11053770 10/29/2000       61 Citations
  • Resistance to myocardial ischemia in five rat strains: is there a genetic component of cardioprotection? (Baker JE, Konorev EA, Gross GJ, Chilian WM, Jacob HJ) Am J Physiol Heart Circ Physiol 2000 Apr;278(4):H1395-400 PMID: 10749737 04/06/2000       51 Citations
  • Adaptation to chronic hypoxia confers tolerance to subsequent myocardial ischemia by increased nitric oxide production. (Baker JE, Holman P, Kalyanaraman B, Griffith OW, Pritchard KA Jr) Ann N Y Acad Sci 1999 Jun 30;874:236-53 PMID: 10415535 07/23/1999       56 Citations
  • Preconditioning in immature rabbit hearts: role of KATP channels. (Baker JE, Holman P, Gross GJ) Circulation 1999 Mar 09;99(9):1249-54 PMID: 10069795 03/09/1999       61 Citations
  • Adaptation of hearts to chronic hypoxia increases tolerance to subsequent ischemia by increased nitric oxide production. (Baker JE, Holman P, Kalyanaraman B, Pritchard KA Jr) Adv Exp Med Biol 1998;454:203-17 PMID: 9889894 01/16/1999       11 Citations
  • Myocardial protection of the hypoxic heart. (Baker JE, Olinger GN) J Thorac Cardiovasc Surg 1997 Jun;113(6):1123-4 PMID: 9202700 06/01/1997       5 Citations
  • Effect of exposure to hypoxia from birth on aldosterone in rabbits: role of unesterified fatty acids. (Raff H, Jankowski BM, Goodfriend TL, Baker JE, Papanek PE) Am J Physiol 1997 Apr;272(4 Pt 2):R1084-7 PMID: 9140005 04/01/1997       7 Citations
  • Increased tolerance of the chronically hypoxic immature heart to ischemia. Contribution of the KATP channel. (Baker JE, Curry BD, Olinger GN, Gross GJ) Circulation 1997 Mar 04;95(5):1278-85 PMID: 9054860 03/04/1997    
  • KATP channel activation in a rabbit model of chronic myocardial hypoxia. (Baker JE, Contney SJ, Gross GJ, Bosnjak ZJ) J Mol Cell Cardiol 1997 Feb;29(2):845-8 PMID: 9140841 02/01/1997       27 Citations
  • Spin label oximetry to assess extracellular oxygen during myocardial ischemia. (Baker JE, Froncisz W, Joseph J, Kalyanaraman B) Free Radic Biol Med 1997;22(1-2):109-15 PMID: 8958135 01/01/1997       22 Citations
  • Postnatal developmental profiles of antioxidant enzymes in heart. (Maulik N, Baker JE, Engelman RM, Das DK) Ann N Y Acad Sci 1996 Sep 30;793:439-48 PMID: 8906189 09/30/1996       6 Citations
  • S-nitrosoglutathione improves functional recovery in the isolated rat heart after cardioplegic ischemic arrest-evidence for a cardioprotective effect of nitric oxide. (Konorev EA, Tarpey MM, Joseph J, Baker JE, Kalyanaraman B) J Pharmacol Exp Ther 1995 Jul;274(1):200-6 PMID: 7616400 07/01/1995       76 Citations
  • Direct effects of halothane and isoflurane in infant rabbit hearts with right ventricular hypertrophy secondary to chronic hypoxemia. (Palmisano BW, Mehner RW, Baker JE, Stowe DF, Bosnjak ZJ, Kampine JP) Anesth Analg 1995 Jun;80(6):1122-8 PMID: 7762838 06/01/1995       10 Citations
  • Tolerance of the developing heart to ischemia: impact of hypoxemia from birth. (Baker EJ, Boerboom LE, Olinger GN, Baker JE) Am J Physiol 1995 Mar;268(3 Pt 2):H1165-73 PMID: 7900870 03/01/1995       75 Citations
  • Nitronyl nitroxides as probes to study the mechanism of vasodilatory action of nitrovasodilators, nitrone spin traps, and nitroxides: role of nitric oxide. (Konorev EA, Tarpey MM, Joseph J, Baker JE, Kalyanaraman B) Free Radic Biol Med 1995 Feb;18(2):169-77 PMID: 7744299 02/01/1995       35 Citations
  • Calcium and cardioplegic protection of the ischemic immature heart: impact of hypoxemia from birth. (Baker EJ, Baker JE) Ann Thorac Surg 1994 Oct;58(4):1123-30 PMID: 7944763 10/01/1994       9 Citations
  • Lack of protection of PBN in isolated heart during ischemia and reperfusion: implications for radical scavenging mechanism. (Baker JE, Konorev EA, Tse SY, Joseph J, Kalyanaraman B) Free Radic Res 1994 Mar;20(3):145-63 PMID: 8019639 03/01/1994       10 Citations
  • Protection of the ischemic immature heart--effect of perfusate reinfusion and composition. (Baker JE, Olinger GN, Boerboom LE) Thorac Cardiovasc Surg 1993 Oct;41(5):274-9 PMID: 8303694 10/01/1993       3 Citations
  • Recovery of hypoxic neonatal hearts after cardioplegic arrest. (Baker JE) Cardiovasc Res 1993 Jun;27(6):1135-6 PMID: 8221776 06/01/1993    
  • Age and protection of the ischemic myocardium: is alkaline cardioplegia appropriate? (Baker JE, Boerboom LE, Olinger GN) Ann Thorac Surg 1993 Mar;55(3):747-55 PMID: 8452442 03/01/1993       16 Citations
  • Vasodilatory and toxic effects of spin traps on aerobic cardiac function. (Konorev EA, Baker JE, Joseph J, Kalyanaraman B) Free Radic Biol Med 1993 Feb;14(2):127-37 PMID: 8425719 02/01/1993       64 Citations
  • Intracellular catalase inhibition does not predispose rat heart to ischemia-reperfusion and hydrogen peroxide-induced injuries. (Konorev EA, Struck AT, Baker JE, Ramanujam S, Thomas JP, Radi R, Kalyanaraman B) Free Radic Res Commun 1993;19(6):397-407 PMID: 8168729 01/01/1993       11 Citations
  • Calcium content of St. Thomas' II cardioplegic solution damages ischemic immature myocardium. (Baker EJ 5th, Olinger GN, Baker JE) Ann Thorac Surg 1991 Oct;52(4):993-9 PMID: 1929665 10/11/1991       21 Citations
  • Cardioplegia-induced damage to ischemic immature myocardium is independent of oxygen availability. (Baker JE, Boerboom LE, Olinger GN) Ann Thorac Surg 1990 Dec;50(6):934-9 PMID: 2241386 12/01/1990       10 Citations
  • On the detection of paramagnetic species in the adriamycin-perfused rat heart: a reappraisal. (Kalyanaraman B, Baker JE) Biochem Biophys Res Commun 1990 May 31;169(1):30-8 PMID: 2161659 05/31/1990       2 Citations
  • Is protection of ischemic neonatal myocardium by cardioplegia species dependent? (Baker JE, Boerboom LE, Olinger GN) J Thorac Cardiovasc Surg 1990 Feb;99(2):280-7 PMID: 2299865 02/01/1990       24 Citations
  • Ischemia-induced changes in myocardial paramagnetic metabolites: implications for intracellular oxy-radical generation. (Baker JE, Kalyanaraman B) FEBS Lett 1989 Feb 27;244(2):311-4 PMID: 2537756 02/27/1989       42 Citations
  • Alpha adrenoceptor subtypes and receptor reserve in human versus canine saphenous vein: sensitivity to blockade by nitroglycerin. (Eskinder H, Hillard CJ, Olinger GN, Christensen CW, Baker JE, Warltier DC, Gross GJ) J Pharmacol Exp Ther 1988 Dec;247(3):941-8 PMID: 2905005 12/01/1988       9 Citations
  • Age-related changes in the ability of hypothermia and cardioplegia to protect ischemic rabbit myocardium. (Baker JE, Boerboom LE, Olinger GN) J Thorac Cardiovasc Surg 1988 Nov;96(5):717-24 PMID: 3184966 11/01/1988       48 Citations
  • Myocardial ischemia and reperfusion: direct evidence for free radical generation by electron spin resonance spectroscopy. (Baker JE, Felix CC, Olinger GN, Kalyanaraman B) Proc Natl Acad Sci U S A 1988 Apr;85(8):2786-9 PMID: 2833754 PMCID: PMC280084 04/01/1988       183 Citations
  • Differing potencies and dose-response characteristics in the ability of slow-calcium-channel blockers to reduce enzyme leakage in the calcium paradox. (Baker JE, Hearse DJ) Adv Myocardiol 1985;6:637-46 PMID: 2581302 01/01/1985       2 Citations
  • Calcium delivery and time: factors affecting the progression of cellular damage during the calcium paradox in the rat heart. (Baker JE, Kemmenoe BH, Hearse DJ, Bullock GR) Cardiovasc Res 1984 Jun;18(6):361-70 PMID: 6331667 06/01/1984       10 Citations
  • The temperature-sensitivity of slow channel calcium blockers in relation to their effect upon the calcium paradox. (Baker JE, Hearse DJ) Eur Heart J 1983 Dec;4 Suppl H:97-103 PMID: 6662136 12/01/1983       4 Citations
  • Slow calcium channel blockers and the calcium paradox: comparative studies in the rat with seven drugs. (Baker JE, Hearse DJ) J Mol Cell Cardiol 1983 Jul;15(7):475-85 PMID: 6312058 07/01/1983       24 Citations
  • The temperature dependence of the calcium paradox: enzymatic, functional and morphological correlates of cellular injury. (Baker JE, Bullock GR, Hearse DJ) J Mol Cell Cardiol 1983 Jun;15(6):393-411 PMID: 6876188 06/01/1983       29 Citations
  • Verapamil and the calcium paradox: a reaffirmation. (Hearse DJ, Baker JE) J Mol Cell Cardiol 1981 Dec;13(12):1087-90 PMID: 7328668 12/01/1981       5 Citations
  • Verapamil and the calcium paradox. (Hearse DJ, Baker JE, Humphrey SM) J Mol Cell Cardiol 1980 Jul;12(7):733-9 PMID: 7411649 07/01/1980       41 Citations
  • Last update: 10/22/2015
    jenkins-FCD Prod-299 9ef562391eceb2b8f95265c767fbba1ce5a52fd6