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John LaDisa PhD

Assistant Professor

Institution: Marquette University
Department: Biomedical Engineering

Member of the Cancer Center
Member of the Cardiovascular Center

I am willing to mentor a junior faculty member.


  • Impact of annular and supra-annular CoreValve deployment locations on aortic and coronary artery hemodynamics. (Kandail HS, Trivedi SD, Shaikh AC, Bajwa TK, O'Hair DP, Jahangir A, LaDisa JF Jr) J Mech Behav Biomed Mater 2018 Oct;86:131-142 PMID: 29986288 07/10/2018    
  • Treating a 20 mm Hg gradient alleviates myocardial hypertrophy in experimental aortic coarctation. (Wendell DC, Friehs I, Samyn MM, Harmann LM, LaDisa JF Jr) J Surg Res 2017 10;218:194-201 PMID: 28985849 PMCID: PMC5679105 10/08/2017    
  • Toward translating near-infrared spectroscopy oxygen saturation data for the non-invasive prediction of spatial and temporal hemodynamics during exercise. (Ellwein L, Samyn MM, Danduran M, Schindler-Ivens S, Liebham S, LaDisa JF Jr) Biomech Model Mechanobiol 2017 02;16(1):75-96 PMID: 27376865 PMCID: PMC5217163 07/05/2016    
  • The Impact of Cardiac Motion on Aortic Valve Flow Used in Computational Simulations of the Thoracic Aorta. (Wendell DC, Samyn MM, Cava JR, Krolikowski MM, LaDisa JF Jr) J Biomech Eng 2016 09 01;138(9) PMID: 27367143 PMCID: PMC4967883 07/02/2016    
  • Image-based quantification of 3D morphology for bifurcations in the left coronary artery: Application to stent design. (Ellwein L, Marks DS, Migrino RQ, Foley WD, Sherman S, LaDisa JF Jr) Catheter Cardiovasc Interv 2016 Jun;87(7):1244-55 PMID: 27251470 PMCID: PMC4896847 06/03/2016       5 Citations
  • Computational replication of the patient-specific stenting procedure for coronary artery bifurcations: From OCT and CT imaging to structural and hemodynamics analyses. (Chiastra C, Wu W, Dickerhoff B, Aleiou A, Dubini G, Otake H, Migliavacca F, LaDisa JF Jr) J Biomech 2016 07 26;49(11):2102-2111 PMID: 26655589 12/15/2015       16 Citations
  • Alagebrium inhibits neointimal hyperplasia and restores distributions of wall shear stress by reducing downstream vascular resistance in obese and diabetic rats. (Wang H, Weihrauch D, Kersten JR, Toth JM, Passerini AG, Rajamani A, Schrepfer S, LaDisa JF Jr) Am J Physiol Heart Circ Physiol 2015 Oct;309(7):H1130-40 PMID: 26254329 PMCID: PMC4865061 08/09/2015       2 Citations
  • Gene Expression in Experimental Aortic Coarctation and Repair: Candidate Genes for Therapeutic Intervention? (LaDisa JF Jr, Bozdag S, Olson J, Ramchandran R, Kersten JR, Eddinger TJ) PLoS One 2015;10(7):e0133356 PMID: 26207811 PMCID: PMC4514739 07/25/2015       2 Citations
  • Cardiovascular magnetic resonance imaging-based computational fluid dynamics/fluid-structure interaction pilot study to detect early vascular changes in pediatric patients with type 1 diabetes. (Samyn MM, Dholakia R, Wang H, Co-Vu J, Yan K, Widlansky ME, LaDisa JF, Simpson P, Alemzadeh R) Pediatr Cardiol 2015 Apr;36(4):851-61 PMID: 25577225 01/13/2015       4 Citations
  • Immersive visualization for enhanced computational fluid dynamics analysis. (Quam DJ, Gundert TJ, Ellwein L, Larkee CE, Hayden P, Migrino RQ, Otake H, LaDisa JF Jr) J Biomech Eng 2015 Mar;137(3) PMID: 25378201 PMCID: PMC4321107 11/08/2014       5 Citations
  • Quantification of local hemodynamic alterations caused by virtual implantation of three commercially available stents for the treatment of aortic coarctation. (Kwon S, Feinstein JA, Dholakia RJ, Ladisa JF Jr) Pediatr Cardiol 2014 Apr;35(4):732-40 PMID: 24259013 PMCID: PMC3959287 11/22/2013       9 Citations
  • Altered hemodynamics, endothelial function, and protein expression occur with aortic coarctation and persist after repair. (Menon A, Eddinger TJ, Wang H, Wendell DC, Toth JM, LaDisa JF Jr) Am J Physiol Heart Circ Physiol 2012 Dec 01;303(11):H1304-18 PMID: 23023871 PMCID: PMC3532538 10/02/2012       18 Citations
  • Including aortic valve morphology in computational fluid dynamics simulations: initial findings and application to aortic coarctation. (Wendell DC, Samyn MM, Cava JR, Ellwein LM, Krolikowski MM, Gandy KL, Pelech AN, Shadden SC, LaDisa JF Jr) Med Eng Phys 2013 Jun;35(6):723-35 PMID: 22917990 PMCID: PMC3577975 08/25/2012    
  • Identification of hemodynamically optimal coronary stent designs based on vessel caliber. (Gundert TJ, Marsden AL, Yang W, Marks DS, LaDisa JF Jr) IEEE Trans Biomed Eng 2012 Jul;59(7):1992-2002 PMID: 22547450 05/02/2012       15 Citations
  • Computational fluid dynamic simulations for determination of ventricular workload in aortic arch obstructions. (Coogan JS, Chan FP, Ladisa JF Jr, Taylor CA, Hanley FL, Feinstein JA) J Thorac Cardiovasc Surg 2013 Feb;145(2):489-495.e1 PMID: 22516390 04/21/2012       7 Citations
  • Optimization of cardiovascular stent design using computational fluid dynamics. (Gundert TJ, Marsden AL, Yang W, LaDisa JF Jr) J Biomech Eng 2012 Jan;134(1):011002 PMID: 22482657 04/10/2012       42 Citations
  • A coupled experimental and computational approach to quantify deleterious hemodynamics, vascular alterations, and mechanisms of long-term morbidity in response to aortic coarctation. (Menon A, Wendell DC, Wang H, Eddinger TJ, Toth JM, Dholakia RJ, Larsen PM, Jensen ES, Ladisa JF Jr) J Pharmacol Toxicol Methods 2012 Jan;65(1):18-28 PMID: 22079597 PMCID: PMC3288451 11/15/2011       19 Citations
  • Computational simulations for aortic coarctation: representative results from a sampling of patients. (LaDisa JF Jr, Alberto Figueroa C, Vignon-Clementel IE, Kim HJ, Xiao N, Ellwein LM, Chan FP, Feinstein JA, Taylor CA) J Biomech Eng 2011 Sep;133(9):091008 PMID: 22010743 PMCID: PMC3705983 10/21/2011       58 Citations
  • Carotid plaque regression following 6-month statin therapy assessed by 3T cardiovascular magnetic resonance: comparison with ultrasound intima media thickness. (Migrino RQ, Bowers M, Harmann L, Prost R, LaDisa JF Jr) J Cardiovasc Magn Reson 2011 Aug 03;13:37 PMID: 21812992 PMCID: PMC3166901 08/05/2011       27 Citations
  • Computational simulations demonstrate altered wall shear stress in aortic coarctation patients treated by resection with end-to-end anastomosis. (LaDisa JF Jr, Dholakia RJ, Figueroa CA, Vignon-Clementel IE, Chan FP, Samyn MM, Cava JR, Taylor CA, Feinstein JA) Congenit Heart Dis 2011 Sep-Oct;6(5):432-43 PMID: 21801315 PMCID: PMC3208403 08/02/2011       37 Citations
  • A rapid and computationally inexpensive method to virtually implant current and next-generation stents into subject-specific computational fluid dynamics models. (Gundert TJ, Shadden SC, Williams AR, Koo BK, Feinstein JA, Ladisa JF Jr) Ann Biomed Eng 2011 May;39(5):1423-37 PMID: 21203844 01/05/2011       39 Citations
  • Local hemodynamic changes caused by main branch stent implantation and subsequent virtual side branch balloon angioplasty in a representative coronary bifurcation. (Williams AR, Koo BK, Gundert TJ, Fitzgerald PJ, LaDisa JF Jr) J Appl Physiol (1985) 2010 Aug;109(2):532-40 PMID: 20507966 05/29/2010       54 Citations
  • Coronary artery bifurcation biomechanics and implications for interventional strategies. (Moore JE Jr, Timmins LH, Ladisa JF Jr) Catheter Cardiovasc Interv 2010 Nov 15;76(6):836-43 PMID: 20506509 05/28/2010       21 Citations
  • Time-efficient patient-specific quantification of regional carotid artery fluid dynamics and spatial correlation with plaque burden. (LaDisa JF Jr, Bowers M, Harmann L, Prost R, Doppalapudi AV, Mohyuddin T, Zaidat O, Migrino RQ) Med Phys 2010 Feb;37(2):784-92 PMID: 20229888 PMCID: PMC2826384 03/17/2010    
  • On coupling a lumped parameter heart model and a three-dimensional finite element aorta model. (Kim HJ, Vignon-Clementel IE, Figueroa CA, LaDisa JF, Jansen KE, Feinstein JA, Taylor CA) Ann Biomed Eng 2009 Nov;37(11):2153-69 PMID: 19609676 07/18/2009       155 Citations
  • Alterations in regional vascular geometry produced by theoretical stent implantation influence distributions of wall shear stress: analysis of a curved coronary artery using 3D computational fluid dynamics modeling. (LaDisa JF Jr, Olson LE, Douglas HA, Warltier DC, Kersten JR, Pagel PS) Biomed Eng Online 2006 Jun 16;5:40 PMID: 16780592 PMCID: PMC1550410 06/20/2006       77 Citations
  • Axial stent strut angle influences wall shear stress after stent implantation: analysis using 3D computational fluid dynamics models of stent foreshortening. (LaDisa JF Jr, Olson LE, Hettrick DA, Warltier DC, Kersten JR, Pagel PS) Biomed Eng Online 2005 Oct 26;4:59 PMID: 16250918 PMCID: PMC1276824 10/28/2005       42 Citations
  • Microfocal X-ray computed tomography post-processing operations for optimizing reconstruction volumes of stented arteries during 3D computational fluid dynamics modeling. (Ladisa JF Jr, Olson LE, Ropella KM, Molthen RC, Haworth ST, Kersten JR, Warltier DC, Pagel PS) Comput Methods Programs Biomed 2005 Aug;79(2):121-34 PMID: 15894401 05/17/2005       2 Citations
  • Antegrade iliac artery stent implantation for the temporal and spatial examination of stent-induced neointimal hyperplasia and alterations in regional fluid dynamics. (LaDisa JF Jr, Meier HT, Olson LE, Kersten JR, Warltier DC, Pagel PS) J Pharmacol Toxicol Methods 2005 Mar-Apr;51(2):115-21 PMID: 15767204 03/16/2005       9 Citations
  • Alterations in wall shear stress predict sites of neointimal hyperplasia after stent implantation in rabbit iliac arteries. (LaDisa JF Jr, Olson LE, Molthen RC, Hettrick DA, Pratt PF, Hardel MD, Kersten JR, Warltier DC, Pagel PS) Am J Physiol Heart Circ Physiol 2005 May;288(5):H2465-75 PMID: 15653759 01/18/2005       110 Citations
  • Circumferential vascular deformation after stent implantation alters wall shear stress evaluated with time-dependent 3D computational fluid dynamics models. (LaDisa JF Jr, Olson LE, Guler I, Hettrick DA, Kersten JR, Warltier DC, Pagel PS) J Appl Physiol (1985) 2005 Mar;98(3):947-57 PMID: 15531564 11/09/2004       90 Citations
  • Cardioprotection by glucose-insulin-potassium: dependence on KATP channel opening and blood glucose concentration before ischemia. (LaDisa JF Jr, Krolikowski JG, Pagel PS, Warltier DC, Kersten JR) Am J Physiol Heart Circ Physiol 2004 Aug;287(2):H601-7 PMID: 15044191 03/27/2004       30 Citations
  • Stent design properties and deployment ratio influence indexes of wall shear stress: a three-dimensional computational fluid dynamics investigation within a normal artery. (LaDisa JF Jr, Olson LE, Guler I, Hettrick DA, Audi SH, Kersten JR, Warltier DC, Pagel PS) J Appl Physiol (1985) 2004 Jul;97(1):424-30; discussion 416 PMID: 14766776 02/10/2004       110 Citations
  • Influence of isoflurane on left atrial function in dogs with pacing-induced cardiomyopathy: evaluation with pressure-volume relationships. (Kehl F, Ladisa JF Jr, Hettrick DA, Kersten JR, Warltier DC, Pagel PS) J Cardiothorac Vasc Anesth 2003 Dec;17(6):709-14 PMID: 14689410 12/23/2003       5 Citations
  • An automated coronary artery occlusion device for stimulating collateral development in vivo. (Rys R, LaDisa JF Jr, Tessmer JP, Gu W, Kersten JR, Warltier DC, Pagel PS) J Pharmacol Toxicol Methods 2002 Sep-Oct;48(2):111-8 PMID: 14565568 10/21/2003       4 Citations
  • Three-dimensional computational fluid dynamics modeling of alterations in coronary wall shear stress produced by stent implantation. (LaDisa JF Jr, Guler I, Olson LE, Hettrick DA, Kersten JR, Warltier DC, Pagel PS) Ann Biomed Eng 2003 Sep;31(8):972-80 PMID: 12918912 08/16/2003       135 Citations
  • Adenosine type 1 (A1) receptors mediate protection against myocardial infarction produced by chronic, intermittent ingestion of ethanol in dogs. (Kehl F, Krolikowski JG, LaDisa JF Jr, Kersten JR, Warltier DC, Pagel PS) Int J Cardiol 2003 Apr;88(2-3):175-82 PMID: 12714196 04/26/2003       6 Citations
  • Reactive oxygen species modulate coronary wall shear stress and endothelial function during hyperglycemia. (Gross ER, LaDisa JF Jr, Weihrauch D, Olson LE, Kress TT, Hettrick DA, Pagel PS, Warltier DC, Kersten JR) Am J Physiol Heart Circ Physiol 2003 May;284(5):H1552-9 PMID: 12543642 01/25/2003       52 Citations
  • Mechanism of preconditioning by isoflurane in rabbits: a direct role for reactive oxygen species. (Tanaka K, Weihrauch D, Kehl F, Ludwig LM, LaDisa JF Jr, Kersten JR, Pagel PS, Warltier DC) Anesthesiology 2002 Dec;97(6):1485-90 PMID: 12459675 12/03/2002       142 Citations
  • Stent implantation alters coronary artery hemodynamics and wall shear stress during maximal vasodilation. (LaDisa JF Jr, Hettrick DA, Olson LE, Guler I, Gross ER, Kress TT, Kersten JR, Warltier DC, Pagel PS) J Appl Physiol (1985) 2002 Dec;93(6):1939-46 PMID: 12391052 10/23/2002       47 Citations
  • Last update: 07/11/2018
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