Jonathan R. Thompson MD
Research Areas of Interest
Biomarkers, TumorCarcinoma, Non-Small-Cell LungClinical Trial, Phase IClinical Trial, Phase IIClinical Trial, Phase IIIImmunotherapyMesotheliomaSmall Cell Lung CarcinomaThymus NeoplasmsTranslational Medical ResearchResearch Experience
Biomarkers, TumorCarcinoma, Non-Small-Cell LungClinical Trial, Phase IClinical Trial, Phase IIClinical Trial, Phase IIIClinical Trials as TopicImmunotherapySmall Cell Lung CarcinomaTranslational Medical ResearchClinical Expertise
Carcinoma, Non-Small-Cell LungCarcinoma, Small CellLung NeoplasmsMesotheliomaThymomaThymus NeoplasmsLeadership Positions
Vice Chair Solid Tumor Early Phase Disease Oriented TeamLeader - Immunotherapy Toxicity ProgramEducational Expertise
Carcinoma, Non-Small-Cell LungImmunotherapyMesotheliomaSmall Cell Lung CarcinomaThymus NeoplasmsPublications (27)
SAPPHIRE: phase III study of sitravatinib plus nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer. (Borghaei H, de Marinis F, Dumoulin D, Reynolds C, Theelen WSME, Percent I, Gutierrez Calderon V, Johnson ML, Madroszyk-Flandin A, Garon EB, He K, Planchard D, Reck M, Popat S, Herbst RS, Leal TA, Shazer RL, Yan X, Harrigan R, Peters S, SAPPHIRE Investigators) Ann Oncol 2024 Jan;35(1):66-76 PMID: 37866811 SCOPUS ID: 2-s2.0-85178324517 10/23/2023 1 CitationMulticenter Phase 1b/2a Clinical Trial of Radioprotectant BIO 300 Oral Suspension for Patients With Non-Small Cell Lung Cancer Receiving Concurrent Chemoradiotherapy. (Simone CB 2nd, Serebrenik AA, Gore EM, Mohindra P, Brown SL, Wang D, Chetty IJ, Vujaskovic Z, Menon S, Thompson J, Fine G, Kaytor MD, Movsas B) Int J Radiat Oncol Biol Phys 2024 Feb 01;118(2):404-414 PMID: 37652301 SCOPUS ID: 2-s2.0-85172016695 09/01/2023 Resected cytokeratin-negative small cell lung carcinoma. (Jain PV, Thompson J, Sheinin Y) BMJ Case Rep 2023 Apr 03;16(4) PMID: 37011997 PMCID: PMC10083812 SCOPUS ID: 2-s2.0-85151707665 04/04/2023 Comprehensive genomic profiling: Does timing matter? (Thapa B, Ahmed G, Szabo A, Kamgar M, Kilari D, Mehdi M, Menon S, Daniel S, Thompson J, Thomas J, George B) Front Oncol 2023;13:1025367 PMID: 36865796 PMCID: PMC9971445 SCOPUS ID: 2-s2.0-85149381128 03/04/2023 3 CitationsThe AXL inhibitor, TP-0903, reverses EMT and shows activity in non-small cell lung cancer preclinical models (Joe R, Matsumura Y, Siddiqui A, Foulks J, Beg M, Thompson J, Yamamoto N, Spira A, Sarantopoulos J, Melear J, Lou Y, Lebedinsky C, Li J, Watanabe A, Warner S) European Journal of Cancer October 2022;174:S57-S58 SCOPUS ID: 2-s2.0-85140454116 10/01/2022 1 CitationPandemic Perspective: Commonalities Between COVID-19 and Cardio-Oncology. (Brown SA, Zaharova S, Mason P, Thompson J, Thapa B, Ishizawar D, Wilkes E, Ahmed G, Rubenstein J, Sanchez J, Joyce D, Kalyanaraman B, Widlansky M) Front Cardiovasc Med 2020;7:568720 PMID: 33344513 PMCID: PMC7746643 SCOPUS ID: 2-s2.0-85115906217 12/22/2020 5 CitationsPandemic Perspective: Commonalities Between COVID-19 and Cardio-Oncology (Sherry-Ann Brown, Svetlana Zaharova, Peter Mason, Jonathan Thompson, Bicky Thapa, David Ishizawar, Erin Wilkes, Gulrayz Ahmed, Jason Rubenstein, Joyce Sanchez, David Joyce, Balaraman Kalyanaraman, Michael Widlansky) Frontiers in Cardiovascular Medicine Front. Cardiovasc. Med., 04 December 2020 12/04/2020 QOLP-01. OUTCOME ASSESSMENT OF MULTIDISCIPLINARY BRAIN TUMOR BOARD MEETING RECOMMENDATIONS FOR BRAIN METASTASIS: IS THERE A GAP? (Fernando Santos-Pinheiro, Joseph Bovi, Wendy Peltier, Jennifer Connelly, Wade Mueller, Michael Straza, Lindsay Puckett, Marianne Crabb, Julianne Leuck, Nathan Zwagerman, Jonathan Thompson, Christopher Schultz, Jennifer Lindstedt, Kimberly Roller-Voigt, Ariel Nelson, Sarah Bichler, Alexandra Leutenegger, Tracy Erlitz, Carolyn Brausch, Hina Saeed, Dustin Hahn, Fernando Santos-Pinheiro) Neuro-Oncology Volume 22, Issue Supplement_2, November 2020, Page ii174 11/09/2020 INNOVATIVE USE OF A CUSTOM MOBILE APPLICATION (APP) BY A BRAIN METASTASES PROGRAM FACILITATES MULTIDISCIPLINARY MANAGEMENT OF PATIENTS AND DECREASED LENGTH OF HOSPITAL STAY (LOS) (Joseph Bovi, Jennifer Lindstedt, Fernando Santos-Pinheiro, Wade Mueller, Straza Michael, Lindsay Puckett, Jonathan Thompson, Ariel Nelson, Wendy Peltier, Carolyn Brausch, Tracy Erlitz, Heather Meerstein, David Atkinson, Marianne Crabb, Julianne Leuck, Kimberly Roller-Voigt, Christopher Schultz) Neuro-Oncology Advances Volume 2, Issue Supplement_2, August 2020, Page ii7 08/04/2020 A phase II study of bemcentinib (BGB324), a first-in-class highly selective AXL inhibitor, with pembrolizumab in pts with advanced NSCLC: OS for stage I and preliminary stage II efficacy (Enriqueta Felip, Paal Brunsvig, Nuria Vinolas, Santiago Ponce Aix, Enric Carcereny Costa, Manuel Dómine Gomez, Jose Manuel Trigo Perez, Edurne Arriola, Rosario Garcia Campelo, James F. Spicer, Jonathan Robert Thompson, Ana Laura Ortega Granados, Robert J Holt, Katherine Lorens, James B. Lorens, Muhammad Shoaib, Abdul Siddiqui, Emmett V. Schmidt, Michael Jon Chisamore, Matthew Krebs) J Clin Oncol J Clin Oncol 37, 2019 (suppl:abstr 9098) 06/02/2019 Proliferative potential and resistance to immune checkpoint blockade in lung cancer patients. (Pabla S, Conroy JM, Nesline MK, Glenn ST, Papanicolau-Sengos A, Burgher B, Hagen J, Giamo V, Andreas J, Lenzo FL, Yirong W, Dy GK, Yau E, Early A, Chen H, Bshara W, Madden KG, Shirai K, Dragnev K, Tafe LJ, Marin D, Zhu J, Clarke J, Labriola M, McCall S, Zhang T, Zibelman M, Ghatalia P, Araujo-Fernandez I, Singavi A, George B, MacKinnon AC, Thompson J, Singh R, Jacob R, Dressler L, Steciuk M, Binns O, Kasuganti D, Shah N, Ernstoff M, Odunsi K, Kurzrock R, Gardner M, Galluzzi L, Morrison C) J Immunother Cancer 2019 Feb 01;7(1):27 PMID: 30709424 PMCID: PMC6359802 SCOPUS ID: 2-s2.0-85060929943 02/03/2019 61 CitationsNext generation sequencing of PD-L1 for predicting response to immune checkpoint inhibitors. (Conroy JM, Pabla S, Nesline MK, Glenn ST, Papanicolau-Sengos A, Burgher B, Andreas J, Giamo V, Wang Y, Lenzo FL, Bshara W, Khalil M, Dy GK, Madden KG, Shirai K, Dragnev K, Tafe LJ, Zhu J, Labriola M, Marin D, McCall SJ, Clarke J, George DJ, Zhang T, Zibelman M, Ghatalia P, Araujo-Fernandez I, de la Cruz-Merino L, Singavi A, George B, MacKinnon AC, Thompson J, Singh R, Jacob R, Kasuganti D, Shah N, Day R, Galluzzi L, Gardner M, Morrison C) J Immunother Cancer 2019 Jan 24;7(1):18 PMID: 30678715 PMCID: PMC6346512 SCOPUS ID: 2-s2.0-85060525068 01/27/2019 67 CitationsUse of Immune Checkpoint Inhibitors (ICIs) in Patients with Refractory Non-Small Cell Lung Cancer (NSCLC) and Poor Performance Status (PS) (Jonathan R Thompson, Carlos Arce-Lara, Smitha Menon) World Conference on Lung Cancer 2018 09/25/2018 Sarcopenia is Associated with Metastatic Burden and is a Negative Prognostic Factor in Metastatic Non-Small Cell Lung Cancer (Chad Glisch, Aniko Szabo, Jonathan R Thompson, Smitha Menon, Jay Patel) World Conference on Lung Cancer 2018 09/25/2018 Genomic alterations of plasma cell-free DNAs in small cell lung cancer and their clinical relevance. (Du M, Thompson J, Fisher H, Zhang P, Huang CC, Wang L) Lung Cancer 2018 Jun;120:113-121 PMID: 29748005 SCOPUS ID: 2-s2.0-85045459821 05/12/2018 36 CitationsLiquid Biopsies and Cancer Immunotherapy. (Thompson JR, Menon SP) Cancer J 2018;24(2):78-83 PMID: 29601334 SCOPUS ID: 2-s2.0-85044928489 03/31/2018 18 CitationsMicrobiome & Immunotherapy: Antibiotic Use Is Associated with Inferior Survival for Lung Cancer Patients Receiving PD-1 Inhibitors (Jonathan R Thompson, Carlos Arce-Lara, Aniko Szabo, Smitha Menon) World Conference on Lung Cancer Abstract 693 10/16/2017 Etanercept and Corticosteroid Therapy for the Treatment of Late-Onset Idiopathic Pneumonia Syndrome. (Thompson J, Yin Z, D'Souza A, Fenske T, Hamadani M, Hari P, Rizzo JD, Pasquini M, Saber W, Shah N, Shaw BE, Shahir K, Banerjee A, Drobyski WR) Biol Blood Marrow Transplant 2017 Nov;23(11):1955-1960 PMID: 28757436 SCOPUS ID: 2-s2.0-85028446880 08/02/2017 19 CitationsApplications of Extracellular RNAs in Oncology. (Thompson JR, Zhu J, Kilari D, Wang L) Mol Diagn Ther 2017 Feb;21(1):1-11 PMID: 27688207 SCOPUS ID: 2-s2.0-84989170631 10/01/2016 2 CitationsTyrosine kinase inhibitors for EGFR- and ALK-mutated non-small cell lung cancer (Thompson JR, Menon SP, Dy GK) ADMET and DMPK 1 October 2016;4(3):186-211 SCOPUS ID: 2-s2.0-85037147152 10/01/2016 2 CitationsTyrosine kinase inhibitors for EGFR- and ALK-mutated non-small cell lung cancer (Jonathan R. Thompson, Smitha P. Menon, Grace K. Dy) ADMET & DMPK ADMET & DMPK 4(3)(2016) 186-211 09/30/2016 Limited utility of routine surveillance imaging for classical Hodgkin lymphoma patients in first complete remission. (Pingali SR, Jewell SW, Havlat L, Bast MA, Thompson JR, Eastwood DC, Bartlett NL, Armitage JO, Wagner-Johnston ND, Vose JM, Fenske TS) Cancer 2014 Jul 15;120(14):2122-9 PMID: 24711253 SCOPUS ID: 2-s2.0-84903791210 04/09/2014 34 CitationsDivergent effects of novel immunomodulatory agents and cyclophosphamide on the risk of engraftment syndrome after autologous peripheral blood stem cell transplantation for multiple myeloma. (Cornell RF, Hari P, Zhang MJ, Zhong X, Thompson J, Fenske TS, Horowitz MM, Komorowski R, Palmer J, Pasquini MC, Rizzo JD, Saber W, Thomas M, Drobyski WR) Biol Blood Marrow Transplant 2013 Sep;19(9):1368-73 PMID: 23806770 SCOPUS ID: 2-s2.0-84882809747 06/29/2013 27 CitationsEndocannabinoid modulation of hyperaemia evoked by physiologically relevant stimuli in the rat primary somatosensory cortex. (Ho WS, Patel S, Thompson JR, Roberts CJ, Stuhr KL, Hillard CJ) Br J Pharmacol 2010 Jun;160(3):736-46 PMID: 20590576 PMCID: PMC2931572 SCOPUS ID: 2-s2.0-77952633980 07/02/2010 10 CitationsInhibition of 2-arachidonoylglycerol catabolism modulates vasoconstriction of rat middle cerebral artery by the thromboxane mimetic, U-46619. (Hillard CJ, Ho WS, Thompson J, Gauthier KM, Wheelock CE, Huang H, Hammock BD) Br J Pharmacol 2007 Nov;152(5):691-8 PMID: 17891162 PMCID: PMC2190024 SCOPUS ID: 2-s2.0-35649005473 09/25/2007 26 CitationsAntianalgesia: stereoselective action of dextro-morphine over levo-morphine on glia in the mouse spinal cord. (Wu HE, Thompson J, Sun HS, Terashvili M, Tseng LF) J Pharmacol Exp Ther 2005 Sep;314(3):1101-8 PMID: 15901793 SCOPUS ID: 2-s2.0-23944521611 05/20/2005 24 CitationsNonopioidergic mechanism mediating morphine-induced antianalgesia in the mouse spinal cord. (Wu HE, Thompson J, Sun HS, Leitermann RJ, Fujimoto JM, Tseng LF) J Pharmacol Exp Ther 2004 Jul;310(1):240-6 PMID: 14999057 SCOPUS ID: 2-s2.0-3042690201 03/05/2004 26 Citations Last update: 01/30/2024