Medical College of Wisconsin
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Joshua Muia PhD

Joshua Muia PhD profile photo picture

Assistant Professor

Institution: Medical College of Wisconsin
Department: Biochemistry

Member of the Cardiovascular Research Center

Publications (21)

  • Proof-of-Concept in a Murine Model of Treatment of Thrombotic Thrombocytopenic Purpura Using Engineered Red Blood Cells. (Roberts KS, Zhang S, Batbayar K, Yan Z, Muia J, Mulvey JJ, Olivier E, Pullman JM, Cataland SR, Bouhassira EE) bioRxiv 2025 Jun 15 PMID: 40661424 PMCID: PMC12259171 07/15/2025    
  • Arginine Methylation by PRMT1 Affects ADAMTS13 Secretion and Enzymatic Activity. (Liu S, Ma M, Qu J, Muia J, Wu Z, Bonnez Q, Vanhoorelbeke K, Zheng L, Zhao X, Zheng XL) Arterioscler Thromb Vasc Biol 2025 Apr;45(4):506-522 PMID: 39945068 PMCID: PMC11945488 SCOPUS ID: 2-s2.0-85219421686 02/13/2025       2 Citations
  • Imbalanced VWF-ADAMTS13 axis contributes to the detrimental impact of a preceding respiratory tract infection on stroke. (Patel RB, Jha AB, Jain A, Verma AK, Saini S, Muia J, Gurung P, Perlman S, Budnik I, Chauhan AK) Blood Adv 2025 Mar 25;9(6):1330-1341 PMID: 39787593 PMCID: PMC11950970 SCOPUS ID: 2-s2.0-105000173792 01/09/2025       2 Citations
  • Thrombotic thrombocytopenic purpura: 100 years of research on Moschcowitz syndrome. (Cataland SR, Coppo P, Scully M, Lämmle B) Blood 2024 Sep 12;144(11):1143-1152 PMID: 38958481 SCOPUS ID: 2-s2.0-85199400335 07/03/2024       13 Citations
  • Removing cross-cultural barriers to participation in the ISTH Congress. (Amigo MC, Mesquita Camelo R, Douketis J, Lee LH, Muia J, Nagao A, Scarlatescu E, Harper AGS) J Thromb Haemost 2024 Jul;22(7):1803-1805 PMID: 38849213 SCOPUS ID: 2-s2.0-85195393654 06/08/2024    
  • Nanoscale organization of CaV2.1 splice isoforms at presynaptic terminals: implications for synaptic vesicle release and synaptic facilitation. (Cingolani LA, Thalhammer A, Jaudon F, Muià J, Baj G) Biol Chem 2023 Sep 26;404(10):931-937 PMID: 37658578 PMCID: PMC10695435 SCOPUS ID: 2-s2.0-85170055337 09/02/2023       3 Citations
  • Cattle-FRETS71, a novel fluorogenic substrate with broad applicability for characterizing ADAMTS13 properties and function. (Barton JC, Anderson C, Miranda FZ, Kelley R, Kremer Hovinga JA, Terrell D, Vesely SK, George JN, Muia J) J Thromb Haemost 2023 Dec;21(12):3393-3401 PMID: 37633642 PMCID: PMC10840809 SCOPUS ID: 2-s2.0-85171294073 08/27/2023       2 Citations
  • ADAMTS13 inhibition to treat acquired von Willebrand syndrome during mechanical circulatory support device implantation. (Deconinck SJ, Nix C, Barth S, Bennek-Schöpping E, Rauch A, Schelpe AS, Roose E, Feys HB, Pareyn I, Vandenbulcke A, Muia J, Vandenbriele C, Susen S, Meyns B, Tersteeg C, Jacobs S, De Meyer SF, Vanhoorelbeke K) J Thromb Haemost 2022 Dec;20(12):2797-2809 PMID: 36128768 PMCID: PMC9669188 SCOPUS ID: 2-s2.0-85139957186 09/22/2022       13 Citations
  • Plasma and rhADAMTS13 reduce trauma-induced organ failure by restoring the ADAMTS13-VWF axis. (Kleinveld DJB, Simons DDG, Dekimpe C, Deconinck SJ, Sloos PH, Maas MAW, Kers J, Muia J, Brohi K, Voorberg J, Vanhoorelbeke K, Hollmann MW, Juffermans NP, BloodNet) Blood Adv 2021 Sep 14;5(17):3478-3491 PMID: 34505883 PMCID: PMC8525227 SCOPUS ID: 2-s2.0-85115926072 09/11/2021       26 Citations
  • Harnessing Twitter to empower scientific engagement and communication: The ISTH 2020 virtual congress experience. (Othman M, Cormier M, Barnes GD, Comer SP, Connors JM, Denorme F, Khorana AA, Las Casas PH, Morla S, Muia J, Ní Áinle F, Taylor KA, van der Wal DE, Weyand AC, Lavin M, ISTH Registration, Marketing teams) Res Pract Thromb Haemost 2021 Feb;5(2):253-260 PMID: 33733023 PMCID: PMC7938622 SCOPUS ID: 2-s2.0-85102192130 03/19/2021       9 Citations
  • Exciting times for the ISTH early career professionals. (Kulkarni K, Chiasakul T, Riva N, Eslick R, Casari C, ISTH Early Career Committee) J Thromb Haemost 2020 Oct;18(10):2437-2438 PMID: 33460230 SCOPUS ID: 2-s2.0-85096406220 01/19/2021       2 Citations
  • International Council for Standardization in Haematology (ICSH) recommendations for laboratory measurement of ADAMTS13. (Mackie I, Mancini I, Muia J, Kremer Hovinga J, Nair S, Machin S, Baker R) Int J Lab Hematol 2020 Dec;42(6):685-696 PMID: 32672897 SCOPUS ID: 2-s2.0-85088121180 07/17/2020       38 Citations
  • Adjuvant low-dose rituximab and plasma exchange for acquired TTP. (Zwicker JI, Muia J, Dolatshahi L, Westfield LA, Nieters P, Rodrigues A, Hamdan A, Antun AG, Metjian A, Sadler JE, ART Investigators) Blood 2019 Sep 26;134(13):1106-1109 PMID: 31331919 PMCID: PMC6764263 SCOPUS ID: 2-s2.0-85072659419 07/25/2019       35 Citations
  • Phylogenetic and functional analysis of ADAMTS13 identifies highly conserved domains essential for allosteric regulation. (Muia J, Zhu J, Greco SC, Vanhoorelbeke K, Gupta G, Westfield LA, Sadler JE) Blood 2019 Apr 25;133(17):1899-1908 PMID: 30700419 PMCID: PMC6484387 SCOPUS ID: 2-s2.0-85065293771 02/01/2019       25 Citations
  • Exploring the "minimal" structure of a functional ADAMTS13 by mutagenesis and small-angle X-ray scattering. (Zhu J, Muia J, Gupta G, Westfield LA, Vanhoorelbeke K, Tolia NH, Sadler JE) Blood 2019 Apr 25;133(17):1909-1918 PMID: 30692120 PMCID: PMC6484386 SCOPUS ID: 2-s2.0-85065336920 01/30/2019       29 Citations
  • Early career professionals: A challenging road (Kulkarni K, Muia J, Boulaftali Y, Blondon M, Lauw MN) Research and Practice in Thrombosis and Haemostasis January 2018;2(1):11-13 SCOPUS ID: 2-s2.0-85085580349 01/01/2018       7 Citations
  • Reflections on scientific collaboration between basic researchers and clinicians. (Muia J, Casari C) J Thromb Haemost 2016 Oct;14(10):1905-1907 PMID: 27515008 SCOPUS ID: 2-s2.0-84994461990 10/28/2016       5 Citations
  • Linker regions and flexibility around the metalloprotease domain account for conformational activation of ADAMTS-13. (Deforche L, Roose E, Vandenbulcke A, Vandeputte N, Feys HB, Springer TA, Mi LZ, Muia J, Sadler JE, Soejima K, Rottensteiner H, Deckmyn H, De Meyer SF, Vanhoorelbeke K) J Thromb Haemost 2015 Nov;13(11):2063-75 PMID: 26391536 PMCID: PMC4778570 SCOPUS ID: 2-s2.0-84946572015 09/24/2015       69 Citations
  • Allosteric activation of ADAMTS13 by von Willebrand factor. (Muia J, Zhu J, Gupta G, Haberichter SL, Friedman KD, Feys HB, Deforche L, Vanhoorelbeke K, Westfield LA, Roth R, Tolia NH, Heuser JE, Sadler JE) Proc Natl Acad Sci U S A 2014 Dec 30;111(52):18584-9 PMID: 25512528 PMCID: PMC4284596 SCOPUS ID: 2-s2.0-84924309931 12/17/2014       122 Citations
  • An optimized fluorogenic ADAMTS13 assay with increased sensitivity for the investigation of patients with thrombotic thrombocytopenic purpura. (Muia J, Gao W, Haberichter SL, Dolatshahi L, Zhu J, Westfield LA, Covill SC, Friedman KD, Sadler JE) J Thromb Haemost 2013 Aug;11(8):1511-8 PMID: 23773695 PMCID: PMC3807872 SCOPUS ID: 2-s2.0-84881590048 06/19/2013       38 Citations
  • Biodegradability of poly (lactic acid), preparation and characterization of PLA/gum Arabic blends (Onyari JM, Mulaa F, Muia J, Shiundu P) Journal of Polymers and the Environment July 2008;16(3):205-212 SCOPUS ID: 2-s2.0-58049205760 07/01/2008       21 Citations
    • Last update: 09/15/2025