Medical College of Wisconsin
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Julian H. Lombard PhD

Professor

Institution: Medical College of Wisconsin
Department: Physiology

Member of the Cancer Center
Member of the Cardiovascular Center


Publications

  • Mechanisms of Mas1 Receptor-Mediated Signaling in the Vascular Endothelium. (Hoffmann BR, Stodola TJ, Wagner JR, Didier DN, Exner EC, Lombard JH, Greene AS) Arterioscler Thromb Vasc Biol 2017 Mar;37(3):433-445 PMID: 28082260 PMCID: PMC5323371 01/14/2017       3 Citations
  • Role of vascular reactive oxygen species in regulating cytochrome P450-4A enzyme expression in Dahl salt-sensitive rats. (Lukaszewicz KM, Paudyal MP, Falck JR, Lombard JH) Microcirculation 2016 10;23(7):540-548 PMID: 27537772 PMCID: PMC5083157 10/28/2016       3 Citations
  • Angiotensin-(1-7) Selectively Induces Relaxation and Modulates Endothelium-Dependent Dilation in Mesenteric Arteries of Salt-Fed Rats. (Raffai G, Lombard JH) J Vasc Res 2016;53(1-2):105-118 PMID: 27676088 PMCID: PMC5079160 10/19/2016       2 Citations
  • Salt, Angiotensin II, Superoxide, and Endothelial Function. (Boegehold MA, Drenjancevic I, Lombard JH) Compr Physiol 2015 Dec 15;6(1):215-54 PMID: 26756632 01/13/2016       9 Citations
  • Increased peripheral vascular disease risk progressively constrains perfusion adaptability in the skeletal muscle microcirculation. (Frisbee JC, Butcher JT, Frisbee SJ, Olfert IM, Chantler PD, Tabone LE, d'Audiffret AC, Shrader CD, Goodwill AG, Stapleton PA, Brooks SD, Brock RW, Lombard JH) Am J Physiol Heart Circ Physiol 2016 Feb 15;310(4):H488-504 PMID: 26702145 PMCID: PMC4796615 12/25/2015       19 Citations
  • The NRF2 knockout rat: a new animal model to study endothelial dysfunction, oxidant stress, and microvascular rarefaction. (Priestley JR, Kautenburg KE, Casati MC, Endres BT, Geurts AM, Lombard JH) Am J Physiol Heart Circ Physiol 2016 Feb 15;310(4):H478-87 PMID: 26637559 PMCID: PMC4796617 12/08/2015       12 Citations
  • The role of cyclo-oxygenase-1 in high-salt diet-induced microvascular dysfunction in humans. (Cavka A, Cosic A, Jukic I, Jelakovic B, Lombard JH, Phillips SA, Seric V, Mihaljevic I, Drenjancevic I) J Physiol 2015 Dec 15;593(24):5313-24 PMID: 26498129 PMCID: PMC4704527 10/27/2015       11 Citations
  • Enhancement of resting-state fcMRI networks by prior sensory stimulation. (Li C, Li Z, Ward BD, Dwinell MR, Lombard JH, Hudetz AG, Pawela CP) Brain Connect 2014 Nov;4(9):760-8 PMID: 25387238 PMCID: PMC4238242 11/12/2014       4 Citations
  • Vascular dysfunction precedes hypertension associated with a blood pressure locus on rat chromosome 12. (Prisco SZ, Priestley JR, Weinberg BD, Prisco AR, Hoffman MJ, Jacob HJ, Flister MJ, Lombard JH, Lazar J) Am J Physiol Heart Circ Physiol 2014 Oct 15;307(8):H1103-10 PMID: 25320330 PMCID: PMC4200336 10/17/2014    
  • Mutation of Plekha7 attenuates salt-sensitive hypertension in the rat. (Endres BT, Priestley JR, Palygin O, Flister MJ, Hoffman MJ, Weinberg BD, Grzybowski M, Lombard JH, Staruschenko A, Moreno C, Jacob HJ, Geurts AM) Proc Natl Acad Sci U S A 2014 Sep 02;111(35):12817-22 PMID: 25136115 PMCID: PMC4156702 08/20/2014       24 Citations
  • Response to "Does angiotensin-dependent superoxide production help to prevent salt-induced endothelial dysfunction in 2 kidney-1 clip hypertensive rats?". (Beyer AM, Fredrich K, Lombard JH) Am J Hypertens 2014 Apr;27(4):640 PMID: 24614863 PMCID: PMC4542814 03/13/2014    
  • Amelioration of salt-induced vascular dysfunction in mesenteric arteries of Dahl salt-sensitive rats by missense mutation of extracellular superoxide dismutase. (Beyer AM, Raffai G, Weinberg BD, Fredrich K, Rodgers MS, Geurts AM, Jacob HJ, Dwinell MR, Lombard JH) Am J Physiol Heart Circ Physiol 2014 Feb;306(3):H339-47 PMID: 24322611 PMCID: PMC3920146 12/11/2013       4 Citations
  • Deficiency of renal cortical EGF increases ENaC activity and contributes to salt-sensitive hypertension. (Pavlov TS, Levchenko V, O'Connor PM, Ilatovskaya DV, Palygin O, Mori T, Mattson DL, Sorokin A, Lombard JH, Cowley AW Jr, Staruschenko A) J Am Soc Nephrol 2013 Jun;24(7):1053-62 PMID: 23599382 PMCID: PMC3699826 04/20/2013       35 Citations
  • Low-dose angiotensin II infusion restores vascular function in cerebral arteries of high salt-fed rats by increasing copper/zinc superoxide dimutase expression. (Durand MJ, Lombard JH) Am J Hypertens 2013 Jun;26(6):739-47 PMID: 23443725 PMCID: PMC3697069 02/28/2013       15 Citations
  • Role of the CYP4A/20-HETE pathway in vascular dysfunction of the Dahl salt-sensitive rat. (Lukaszewicz KM, Lombard JH) Clin Sci (Lond) 2013 Jun;124(12):695-700 PMID: 23438293 PMCID: PMC4106241 02/27/2013       19 Citations
  • PPAR-ϒ pathway to vascular dysfunction. (Lombard JH, Cowley AW Jr) Cell Metab 2012 Oct 03;16(4):410-1 PMID: 23040065 10/09/2012    
  • Introgression of Brown Norway CYP4A genes on to the Dahl salt-sensitive background restores vascular function in SS-5(BN) consomic rats. (Lukaszewicz KM, Falck JR, Manthati VL, Lombard JH) Clin Sci (Lond) 2013 Mar;124(5):333-42 PMID: 22938512 PMCID: PMC3791890 09/04/2012       6 Citations
  • Dahl salt-sensitive rats are protected against vascular defects related to diet-induced obesity. (Beyer AM, Raffai G, Weinberg B, Fredrich K, Lombard JH) Hypertension 2012 Aug;60(2):404-10 PMID: 22710645 PMCID: PMC3444144 06/20/2012       12 Citations
  • Acute and chronic angiotensin-(1-7) restores vasodilation and reduces oxidative stress in mesenteric arteries of salt-fed rats. (Raffai G, Durand MJ, Lombard JH) Am J Physiol Heart Circ Physiol 2011 Oct;301(4):H1341-52 PMID: 21803946 PMCID: PMC3197355 08/02/2011       37 Citations
  • Introgression of the Brown Norway renin allele onto the Dahl salt-sensitive genetic background increases Cu/Zn SOD expression in cerebral arteries. (Durand MJ, Lombard JH) Am J Hypertens 2011 May;24(5):563-8 PMID: 21331057 PMCID: PMC3285562 02/19/2011       13 Citations
  • Microcirculation in a mouse model of Duchenne muscular dystrophy: another blow to the vascular hypothesis? (Lombard JH) J Appl Physiol (1985) 2011 Mar;110(3):587-8 PMID: 21212249 01/08/2011       3 Citations
  • High-salt diet and hypertension: focus on the renin-angiotensin system. (Drenjančević-Perić I, Jelaković B, Lombard JH, Kunert MP, Kibel A, Gros M) Kidney Blood Press Res 2011;34(1):1-11 PMID: 21071956 PMCID: PMC3214830 11/13/2010       59 Citations
  • Modulation by cytochrome P450-4A ω-hydroxylase enzymes of adrenergic vasoconstriction and response to reduced PO₂ in mesenteric resistance arteries of Dahl salt-sensitive rats. (Raffai G, Wang J, Roman RJ, Anjaiah S, Weinberg B, Falck JR, Lombard JH) Microcirculation 2010 Oct;17(7):525-35 PMID: 21040118 PMCID: PMC3057905 11/03/2010       9 Citations
  • Impaired relaxation of cerebral arteries in the absence of elevated salt intake in normotensive congenic rats carrying the Dahl salt-sensitive renin gene. (Durand MJ, Moreno C, Greene AS, Lombard JH) Am J Physiol Heart Circ Physiol 2010 Dec;299(6):H1865-74 PMID: 20852041 PMCID: PMC3006280 09/21/2010       15 Citations
  • Vascular responses in aortic rings of a consomic rat panel derived from the Fawn Hooded Hypertensive strain. (Kunert MP, Dwinell MR, Lombard JH) Physiol Genomics 2010 Nov 29;42A(4):244-58 PMID: 20841496 PMCID: PMC3008365 09/16/2010       8 Citations
  • Angiotensin-(1-7) and low-dose angiotensin II infusion reverse salt-induced endothelial dysfunction via different mechanisms in rat middle cerebral arteries. (Durand MJ, Raffai G, Weinberg BD, Lombard JH) Am J Physiol Heart Circ Physiol 2010 Oct;299(4):H1024-33 PMID: 20656887 PMCID: PMC2957344 07/27/2010       35 Citations
  • Uncoupling protein 2 (UCP2): Another player in the complex drama of vascular salt sensitivity. (Lombard JH) Am J Hypertens 2010 Aug;23(8):816 PMID: 20644528 07/21/2010       4 Citations
  • Depression, psychological stress, vascular dysfunction, and cardiovascular disease: thinking outside the barrel. (Lombard JH) J Appl Physiol (1985) 2010 May;108(5):1025-6 PMID: 20203070 03/06/2010       16 Citations
  • Restoration of cerebral vascular relaxation in renin congenic rats by introgression of the Dahl R renin gene. (Drenjancevic-Peric I, Weinberg BD, Greene AS, Lombard JH) Am J Hypertens 2010 Mar;23(3):243-8 PMID: 19959997 PMCID: PMC2924749 12/05/2009       9 Citations
  • CYP450 4A inhibition attenuates O2 induced arteriolar constriction in chronic but not acute Goldblatt hypertension. (Kunert MP, Friesma J, Falck JR, Lombard JH) Microvasc Res 2009 Dec;78(3):442-6 PMID: 19761780 PMCID: PMC2784231 09/19/2009       4 Citations
  • Angiotensin II maintains cerebral vascular relaxation via EGF receptor transactivation and ERK1/2. (McEwen ST, Balus SF, Durand MJ, Lombard JH) Am J Physiol Heart Circ Physiol 2009 Oct;297(4):H1296-303 PMID: 19684181 PMCID: PMC2770770 08/18/2009       13 Citations
  • Reduced oxidant stress, increased NO-dependent vasodilatation, and improved endothelial function with voluntary exercise in old mice: another excuse for long walks on the beach. (Lombard JH) J Physiol 2009 Jul 01;587(Pt 13):3059 PMID: 19567741 PMCID: PMC2727009 07/02/2009    
  • Time-course and mechanisms of restored vascular relaxation by reduced salt intake and angiotensin II infusion in rats fed a high-salt diet. (McEwen ST, Schmidt JR, Somberg L, Cruz Lde L, Lombard JH) Microcirculation 2009 Apr;16(3):220-34 PMID: 19235625 PMCID: PMC2652508 02/25/2009       21 Citations
  • Modulation of vascular O2 responses by cytochrome 450-4A omega-hydroxylase metabolites in Dahl salt-sensitive rats. (Wang J, Schmidt JR, Roman RJ, Anjaiah S, Falck JR, Lombard JH) Microcirculation 2009 May;16(4):345-54 PMID: 19225982 PMCID: PMC2672112 02/20/2009       11 Citations
  • Sex-specific differences in chromosome-dependent regulation of vascular reactivity in female consomic rat strains from a SSxBN cross. (Kunert MP, Dwinell MR, Drenjancevic Peric I, Lombard JH) Am J Physiol Regul Integr Comp Physiol 2008 Aug;295(2):R516-27 PMID: 18509103 PMCID: PMC2519925 05/30/2008       7 Citations
  • Does 20-hydroxyeicosatetraenoic acid contribute to sex differences in cardiovascular risk by increasing oxidative stress? (Roman RJ, Lombard JH) Hypertension 2007 Jul;50(1):37-8 PMID: 17548717 06/06/2007       8 Citations
  • Effect of high-salt diet on vascular relaxation and oxidative stress in mesenteric resistance arteries. (Zhu J, Huang T, Lombard JH) J Vasc Res 2007;44(5):382-90 PMID: 17510561 05/19/2007       66 Citations
  • Consomic strategies to localize genomic regions related to vascular reactivity in the Dahl salt-sensitive rat. (Kunert MP, Drenjancevic-Peric I, Dwinell MR, Lombard JH, Cowley AW Jr, Greene AS, Kwitek AE, Jacob HJ) Physiol Genomics 2006 Aug 16;26(3):218-25 PMID: 16772359 06/15/2006       20 Citations
  • Role of superoxide and angiotensin II suppression in salt-induced changes in endothelial Ca2+ signaling and NO production in rat aorta. (Zhu J, Drenjancevic-Peric I, McEwen S, Friesema J, Schulta D, Yu M, Roman RJ, Lombard JH) Am J Physiol Heart Circ Physiol 2006 Aug;291(2):H929-38 PMID: 16603691 04/11/2006       31 Citations
  • BN phenome: detailed characterization of the cardiovascular, renal, and pulmonary systems of the sequenced rat. (Kwitek AE, Jacob HJ, Baker JE, Dwinell MR, Forster HV, Greene AS, Kunert MP, Lombard JH, Mattson DL, Pritchard KA Jr, Roman RJ, Tonellato PJ, Cowley AW Jr) Physiol Genomics 2006 Apr 13;25(2):303-13 PMID: 16478827 02/16/2006       26 Citations
  • A novel mechanism for regulation of retinal blood flow by lactate: gap junctions, hypoxia, and pericytes. (Lombard JH) Am J Physiol Heart Circ Physiol 2006 Mar;290(3):H921-2 PMID: 16467461 02/10/2006       8 Citations
  • Chronic intermittent hypoxia alters NE reactivity and mechanics of skeletal muscle resistance arteries. (Phillips SA, Olson EB, Lombard JH, Morgan BJ) J Appl Physiol (1985) 2006 Apr;100(4):1117-23 PMID: 16357071 12/17/2005       46 Citations
  • Chronic At1 receptor blockade alters the mechanisms mediating hypoxic dilation in middle cerebral arteries. (Phillips SA, Lombard JH) J Cardiovasc Pharmacol 2005 Nov;46(5):706-12 PMID: 16220079 10/13/2005       11 Citations
  • Restoration of normal vascular relaxation mechanisms in cerebral arteries by chromosomal substitution in consomic SS.13BN rats. (Drenjancevic-Peric I, Phillips SA, Falck JR, Lombard JH) Am J Physiol Heart Circ Physiol 2005 Jul;289(1):H188-95 PMID: 15778273 03/22/2005       27 Citations
  • Arteriolar responses to vasodilator stimuli and elevated P(O2) in renin congenic and Dahl salt-sensitive rats. (Drenjancevic-Peric I, Greene AS, Kunert MP, Lombard JH) Microcirculation 2004 Dec;11(8):669-77 PMID: 15726834 02/25/2005       14 Citations
  • Reduced angiotensin II and oxidative stress contribute to impaired vasodilation in Dahl salt-sensitive rats on low-salt diet. (Drenjancevic-Peric I, Lombard JH) Hypertension 2005 Apr;45(4):687-91 PMID: 15710779 02/16/2005       34 Citations
  • Effects of high-salt diet on CYP450-4A omega-hydroxylase expression and active tone in mesenteric resistance arteries. (Wang J, Roman RJ, Falck JR, de la Cruz L, Lombard JH) Am J Physiol Heart Circ Physiol 2005 Apr;288(4):H1557-65 PMID: 15576442 12/04/2004       29 Citations
  • Salt-induced ANG II suppression impairs the response of cerebral artery smooth muscle cells to prostacyclin. (Zhu J, Yu M, Friesema J, Huang T, Roman RJ, Lombard JH) Am J Physiol Heart Circ Physiol 2005 Feb;288(2):H908-13 PMID: 15486030 10/16/2004       10 Citations
  • Expression of cytochrome P450-4A isoforms in the rat cremaster muscle microcirculation. (Wang J, Maier KG, Roman RJ, De La Cruz L, Zhu J, Henderson L, Lombard JH) Microcirculation 2004 Jan-Feb;11(1):89-96 PMID: 15280100 07/29/2004       10 Citations
  • Evaluation of cytochrome P450-4A omega-hydroxylase and 20-hydroxyeicosatetraenoic acid as an O2 sensing mechanism in the microcirculation. (Lombard JH, Frisbee JC, Roman RJ, Falck JR) Methods Enzymol 2004;381:140-65 PMID: 15063671 04/06/2004       4 Citations
  • Chronic AT(1) receptor blockade alters mechanisms mediating responses to hypoxia in rat skeletal muscle resistance arteries. (Phillips SA, Drenjancevic-Peric I, Frisbee JC, Lombard JH) Am J Physiol Heart Circ Physiol 2004 Aug;287(2):H545-52 PMID: 15044197 03/27/2004       11 Citations
  • Introgression of chromosome 13 in Dahl salt-sensitive genetic background restores cerebral vascular relaxation. (Drenjancevic-Peric I, Lombard JH) Am J Physiol Heart Circ Physiol 2004 Aug;287(2):H957-62 PMID: 15031125 03/20/2004       30 Citations
  • Effect of high-salt diet on NO release and superoxide production in rat aorta. (Zhu J, Mori T, Huang T, Lombard JH) Am J Physiol Heart Circ Physiol 2004 Feb;286(2):H575-83 PMID: 14527935 10/07/2003       79 Citations
  • Chronic intermittent hypoxia impairs endothelium-dependent dilation in rat cerebral and skeletal muscle resistance arteries. (Phillips SA, Olson EB, Morgan BJ, Lombard JH) Am J Physiol Heart Circ Physiol 2004 Jan;286(1):H388-93 PMID: 14512283 09/27/2003       95 Citations
  • Skeletal muscle arteriolar reactivity in SS.BN13 consomic rats and Dahl salt-sensitive rats. (Drenjancevic-Peric I, Frisbee JC, Lombard JH) Hypertension 2003 May;41(5):1012-5 PMID: 12682080 04/19/2003       24 Citations
  • High-salt diet impairs vascular relaxation mechanisms in rat middle cerebral arteries. (Lombard JH, Sylvester FA, Phillips SA, Frisbee JC) Am J Physiol Heart Circ Physiol 2003 Apr;284(4):H1124-33 PMID: 12456391 11/29/2002       51 Citations
  • Interaction of myogenic mechanisms and hypoxic dilation in rat middle cerebral arteries. (Liu Y, Harder DR, Lombard JH) Am J Physiol Heart Circ Physiol 2002 Dec;283(6):H2276-81 PMID: 12388266 10/22/2002       13 Citations
  • Foreword to the special issue on microcirculatory adaptations to hypertension. (Lombard JH) Microcirculation 2002;9(4):221-3 PMID: 12152100 08/02/2002    
  • Integration of hypoxic dilation signaling pathways for skeletal muscle resistance arteries. (Frisbee JC, Maier KG, Falck JR, Roman RJ, Lombard JH) Am J Physiol Regul Integr Comp Physiol 2002 Aug;283(2):R309-19 PMID: 12121842 07/18/2002       46 Citations
  • High-salt diet depresses acetylcholine reactivity proximal to NOS activation in cerebral arteries. (Sylvester FA, Stepp DW, Frisbee JC, Lombard JH) Am J Physiol Heart Circ Physiol 2002 Jul;283(1):H353-63 PMID: 12063309 06/14/2002       40 Citations
  • Parenchymal tissue cytochrome P450 4A enzymes contribute to oxygen-induced alterations in skeletal muscle arteriolar tone. (Frisbee JC, Lombard JH) Microvasc Res 2002 May;63(3):340-3 PMID: 11969311 04/24/2002       8 Citations
  • Differential effect of cytochrome P-450 omega-hydroxylase inhibition on O2-induced constriction of arterioles in SHR with early and established hypertension. (Kunert MP, Roman RJ, Falck JR, Lombard JH) Microcirculation 2001 Dec;8(6):435-43 PMID: 11781816 01/10/2002       22 Citations
  • Role of prostanoids and 20-HETE in mediating oxygen-induced constriction of skeletal muscle resistance arteries. (Frisbee JC, Krishna UM, Falck JR, Lombard JH) Microvasc Res 2001 Nov;62(3):271-83 PMID: 11678630 10/27/2001       20 Citations
  • High-salt diet impairs hypoxia-induced cAMP production and hyperpolarization in rat skeletal muscle arteries. (Frisbee JC, Sylvester FA, Lombard JH) Am J Physiol Heart Circ Physiol 2001 Oct;281(4):H1808-15 PMID: 11557575 09/15/2001       31 Citations
  • Relative contributions of cyclooxygenase- and cytochrome P450 omega-hydroxylase-dependent pathways to hypoxic dilation of skeletal muscle resistance arteries. (Frisbee JC, Roman RJ, Krishna UM, Falck JR, Lombard JH) J Vasc Res 2001 Jul-Aug;38(4):305-14 PMID: 11455201 07/17/2001       27 Citations
  • Altered mechanisms underlying hypoxic dilation of skeletal muscle resistance arteries of hypertensive versus normotensive Dahl rats. (Frisbee JC, Roman RJ, Murali Krishna U, Falck JR, Lombard JH) Microcirculation 2001 Apr;8(2):115-27 PMID: 11379791 05/31/2001       33 Citations
  • Angiotensin II AT1 receptors preserve vasodilator reactivity in skeletal muscle resistance arteries. (Weber DS, Lombard JH) Am J Physiol Heart Circ Physiol 2001 May;280(5):H2196-202 PMID: 11299222 04/12/2001       37 Citations
  • 20-HETE contributes to myogenic activation of skeletal muscle resistance arteries in Brown Norway and Sprague-Dawley rats. (Frisbee JC, Roman RJ, Falck JR, Krishna UM, Lombard JH) Microcirculation 2001 Feb;8(1):45-55 PMID: 11296852 04/12/2001       30 Citations
  • Cytochrome P-450 omega-hydroxylase: a potential O(2) sensor in rat arterioles and skeletal muscle cells. (Kunert MP, Roman RJ, Alonso-Galicia M, Falck JR, Lombard JH) Am J Physiol Heart Circ Physiol 2001 Apr;280(4):H1840-5 PMID: 11247799 03/15/2001       45 Citations
  • 20-HETE modulates myogenic response of skeletal muscle resistance arteries from hypertensive Dahl-SS rats. (Frisbee JC, Roman RJ, Krishna UM, Falck JR, Lombard JH) Am J Physiol Heart Circ Physiol 2001 Mar;280(3):H1066-74 PMID: 11179048 02/17/2001       38 Citations
  • Functional studies of the cerebral circulation. (Lombard JH) Methods Mol Med 2001;51:497-514 PMID: 21331739 01/01/2001    
  • Microvascular flow and tissue PO(2) in skeletal muscle of chronic reduced renal mass hypertensive rats. (Lombard JH, Frisbee JC, Greene AS, Hudetz AG, Roman RJ, Tonellato PJ) Am J Physiol Heart Circ Physiol 2000 Nov;279(5):H2295-302 PMID: 11045965 10/25/2000       14 Citations
  • Longitudinal differences in vascular control mechanisms in isolated resistance arteries of the rat cremaster muscle. (Sylvester FA, Frisbee JC, Lombard JH) Microvasc Res 2000 Sep;60(2):160-7 PMID: 10964590 08/31/2000       4 Citations
  • Contribution of extrinsic factors and intrinsic vascular alterations to reduced arteriolar reactivity with high-salt diet and hypertension. (Frisbee JC, Sylvester FA, Lombard JH) Microcirculation 2000 Aug;7(4):281-9 PMID: 10963633 08/30/2000       4 Citations
  • Impairment of flow-induced dilation of skeletal muscle arterioles with elevated oxygen in normotensive and hypertensive rats. (Frisbee JC, Roman RJ, Falck JR, Linderman JR, Lombard JH) Microvasc Res 2000 Jul;60(1):37-48 PMID: 10873513 06/30/2000       17 Citations
  • Short-term angiotensin converting enzyme inhibition reduces basal tone and dilator reactivity in skeletal muscle arterioles. (Frisbee JC, Lombard JH) Am J Hypertens 2000 Apr;13(4 Pt 1):389-95 PMID: 10821341 05/23/2000       7 Citations
  • Alterations in skeletal muscle microvascular hematocrit with short-term reduced renal mass hypertension. (Frisbee JC, Lombard JH) Microvasc Res 2000 May;59(3):390-3 PMID: 10792971 05/04/2000    
  • Contribution of cytochrome P-450 omega-hydroxylase to altered arteriolar reactivity with high-salt diet and hypertension. (Frisbee JC, Falck JR, Lombard JH) Am J Physiol Heart Circ Physiol 2000 May;278(5):H1517-26 PMID: 10775129 04/25/2000       53 Citations
  • Altered structure and mechanics of skeletal muscle arteries with high-salt diet and reduced renal mass hypertension. (Frisbee JC, Weber DS, Liu Y, DeBruin JA, Lombard JH) Microvasc Res 2000 Mar;59(2):323-8 PMID: 10684739 02/24/2000       7 Citations
  • Reduced renal mass hypertension, but not high salt diet, alters skeletal muscle arteriolar distensibility and myogenic responses. (Frisbee JC, Lombard JH) Microvasc Res 2000 Mar;59(2):255-64 PMID: 10684731 02/24/2000       4 Citations
  • Elevated salt intake impairs dilation of rat skeletal muscle resistance arteries via ANG II suppression. (Weber DS, Lombard JH) Am J Physiol Heart Circ Physiol 2000 Feb;278(2):H500-6 PMID: 10666081 02/09/2000       51 Citations
  • Increased intravascular pressure does not enhance skeletal muscle arteriolar constriction to oxygen or angiotensin II. (Frisbee JC, Lombard JH) Microvasc Res 2000 Jan;59(1):176-80 PMID: 10625586 01/08/2000       3 Citations
  • Development and reversibility of altered skeletal muscle arteriolar structure and reactivity with high salt diet and reduced renal mass hypertension. (Frisbee JC, Lombard JH) Microcirculation 1999 Sep;6(3):215-25 PMID: 10501095 09/29/1999       25 Citations
  • Elevated oxygen tension inhibits flow-induced dilation of skeletal muscle arterioles. (Frisbee JC, Lombard JH) Microvasc Res 1999 Sep;58(2):99-107 PMID: 10458925 08/25/1999       11 Citations
  • Chronic captopril administration decreases vasodilator responses in skeletal muscle arterioles. (Frisbee JC, Weber DS, Lombard JH) Am J Hypertens 1999 Jul;12(7):705-15 PMID: 10411368 07/20/1999       17 Citations
  • Selective potentiation of angiotensin-induced constriction of skeletal muscle resistance arteries by chronic elevations in dietary salt intake. (Weber DS, Frisbee JC, Lombard JH) Microvasc Res 1999 May;57(3):310-9 PMID: 10329257 05/18/1999       19 Citations
  • Acute elevations in salt intake and reduced renal mass hypertension compromise arteriolar dilation in rat cremaster muscle. (Frisbee JC, Lombard JH) Microvasc Res 1999 May;57(3):273-83 PMID: 10329253 05/18/1999       30 Citations
  • Loss of endothelium and receptor-mediated dilation in pial arterioles of rats fed a short-term high salt diet. (Liu Y, Rusch NJ, Lombard JH) Hypertension 1999 Feb;33(2):686-8 PMID: 10024328 02/19/1999       56 Citations
  • Electrical and mechanical responses of rat middle cerebral arteries to reduced PO2 and prostacyclin. (Lombard JH, Liu Y, Fredricks KT, Bizub DM, Roman RJ, Rusch NJ) Am J Physiol 1999 Feb;276(2 Pt 2):H509-16 PMID: 9950852 02/10/1999       51 Citations
  • Cytochrome P-450 omega-hydroxylase senses O2 in hamster muscle, but not cheek pouch epithelium, microcirculation. (Lombard JH, Kunert MP, Roman RJ, Falck JR, Harder DR, Jackson WF) Am J Physiol 1999 Feb;276(2 Pt 2):H503-8 PMID: 9950851 02/10/1999       38 Citations
  • Chronic elevations in salt intake and reduced renal mass hypertension compromise mechanisms of arteriolar dilation. (Frisbee JC, Lombard JH) Microvasc Res 1998 Nov;56(3):218-27 PMID: 9828160 11/26/1998       50 Citations
  • Localization of the ANG II type 2 receptor in the microcirculation of skeletal muscle. (Nora EH, Munzenmaier DH, Hansen-Smith FM, Lombard JH, Greene AS) Am J Physiol 1998 Oct;275(4 Pt 2):H1395-403 PMID: 9746490 09/24/1998       58 Citations
  • Gender-specific protection from microvessel rarefaction in female hypertensive rats. (Papanek PE, Rieder MJ, Lombard JH, Greene AS) Am J Hypertens 1998 Aug;11(8 Pt 1):998-1005 PMID: 9715794 08/26/1998       10 Citations
  • Response of resistance arteries to reduced PO2 and vasodilators during hypertension and elevated salt intake. (Liu Y, Fredricks KT, Roman RJ, Lombard JH) Am J Physiol 1997 Aug;273(2 Pt 2):H869-77 PMID: 9277505 08/01/1997       64 Citations
  • Hypoxia-induced hyperpolarization is not associated with vasodilation of bovine coronary resistance arteries. (Gauthier-Rein KM, Bizub DM, Lombard JH, Rusch NJ) Am J Physiol 1997 Mar;272(3 Pt 2):H1462-9 PMID: 9087625 03/01/1997       23 Citations
  • Rapid microvessel rarefaction with elevated salt intake and reduced renal mass hypertension in rats. (Hansen-Smith FM, Morris LW, Greene AS, Lombard JH) Circ Res 1996 Aug;79(2):324-30 PMID: 8756011 08/01/1996    
  • Identification of a putative microvascular oxygen sensor. (Harder DR, Narayanan J, Birks EK, Liard JF, Imig JD, Lombard JH, Lange AR, Roman RJ) Circ Res 1996 Jul;79(1):54-61 PMID: 8925569 07/01/1996       162 Citations
  • Low-affinity hemoglobin increases tissue PO2 and decreases arteriolar diameter and flow in the rat cremaster muscle. (Kunert MP, Liard JF, Abraham DJ, Lombard JH) Microvasc Res 1996 Jul;52(1):58-68 PMID: 8812756 07/01/1996       39 Citations
  • Responses of cremasteric arterioles of spontaneously hypertensive rats to changes in extracellular K+ concentration. (Lombard JH, Stekiel WJ) Microcirculation 1995 Dec;2(4):355-62 PMID: 8714816 12/01/1995       13 Citations
  • Effect of hypoxia on force, intracellular pH and Ca2+ concentration in rat cerebral and mesenteric small arteries. (Aalkjaer C, Lombard JH) J Physiol 1995 Jan 15;482 ( Pt 2):409-19 PMID: 7714832 PMCID: PMC1157739 01/15/1995       35 Citations
  • Hypoxia increases the activity of Ca(2+)-sensitive K+ channels in cat cerebral arterial muscle cell membranes. (Gebremedhin D, Bonnet P, Greene AS, England SK, Rusch NJ, Lombard JH, Harder DR) Pflugers Arch 1994 Oct;428(5-6):621-30 PMID: 7838685 10/01/1994       91 Citations
  • Response of extraparenchymal resistance arteries of rat skeletal muscle to reduced PO2. (Fredricks KT, Liu Y, Lombard JH) Am J Physiol 1994 Aug;267(2 Pt 2):H706-15 PMID: 8067426 08/01/1994       86 Citations
  • Role of endothelium and arterial K+ channels in mediating hypoxic dilation of middle cerebral arteries. (Fredricks KT, Liu Y, Rusch NJ, Lombard JH) Am J Physiol 1994 Aug;267(2 Pt 2):H580-6 PMID: 8067414 08/01/1994       109 Citations
  • Myogenic activation of canine small renal arteries after nonchemical removal of the endothelium. (Liu Y, Harder DR, Lombard JH) Am J Physiol 1994 Jul;267(1 Pt 2):H302-7 PMID: 8048595 07/01/1994       47 Citations
  • Salt intake and angiotensin II alter microvessel density in the cremaster muscle of normal rats. (Hernandez I, Cowley AW Jr, Lombard JH, Greene AS) Am J Physiol 1992 Sep;263(3 Pt 2):H664-7 PMID: 1415589 09/11/1992       71 Citations
  • Cyclooxygenase products do not modulate angiotensin II-induced contractions of human chorionic plate arteries. (Sorokin G, Grant NM, Egan BM, Lombard JH) Am J Obstet Gynecol 1992 Jul;167(1):110-4 PMID: 1279972 07/01/1992       9 Citations
  • Effect of microvascular rarefaction on tissue oxygen delivery in hypertension. (Greene AS, Tonellato PJ, Zhang Z, Lombard JH, Cowley AW Jr) Am J Physiol 1992 May;262(5 Pt 2):H1486-93 PMID: 1590452 05/11/1992       43 Citations
  • Performance on multiple choice/short answer tests is not a sufficient criterion for evaluating the educational value of live animal laboratories in the teaching of physiology. (Dawson CA, Cowley AW Jr, Spurr GB, Osborn JL, Raff H, Forster HV, Harder DR, Liard JF, Lombard JH, Stekiel WJ) Am J Physiol 1991 Dec;261(6 Pt 3):S34-5 PMID: 1755480 12/11/1991       5 Citations
  • Structural alterations of microvascular smooth muscle cells in reduced renal mass hypertension. (Hansen-Smith F, Greene AS, Cowley AW Jr, Lougee L, Lombard JH) Hypertension 1991 Jun;17(6 Pt 2):902-8 PMID: 2045171 06/01/1991       13 Citations
  • Sympathetic neural control of vascular muscle in reduced renal mass hypertension. (Stekiel WJ, Contney SJ, Lombard JH) Hypertension 1991 Jun;17(6 Pt 2):1185-91 PMID: 2045163 06/01/1991       21 Citations
  • Assessment of muscle blood flow by laser-Doppler flowmetry during hemorrhage in SHR. (Lombard JH, Roman RJ) Am J Physiol 1990 Sep;259(3 Pt 2):H860-5 PMID: 2204279 09/01/1990       13 Citations
  • Effect of nifedipine on endothelin induced contractions of skeletal muscle arterioles of spontaneously hypertensive rats. (Lougee L, Hinojosa-Laborde C, Harder DR, Lombard JH) Microcirc Endothelium Lymphatics 1990 Aug-Oct;6(4-5):355-68 PMID: 2280745 08/01/1990       3 Citations
  • Enhanced norepinephrine sensitivity in renal arteries at elevated transmural pressure. (Lombard JH, Eskinder H, Kauser K, Osborn JL, Harder DR) Am J Physiol 1990 Jul;259(1 Pt 2):H29-33 PMID: 2375412 07/01/1990       38 Citations
  • Structural changes during microvascular rarefaction in chronic hypertension. (Hansen-Smith F, Greene AS, Cowley AW Jr, Lombard JH) Hypertension 1990 Jun;15(6 Pt 2):922-8 PMID: 2351442 06/01/1990       65 Citations
  • Microvessel changes in hypertension measured by Griffonia simplicifolia I lectin. (Greene AS, Lombard JH, Cowley AW Jr, Hansen-Smith FM) Hypertension 1990 Jun;15(6 Pt 2):779-83 PMID: 2351431 06/01/1990       66 Citations
  • Role of the vascular endothelium in regulating the response of small arteries of the dog kidney to transmural pressure elevation and reduced PO2. (Eskinder H, Harder DR, Lombard JH) Circ Res 1990 May;66(5):1427-35 PMID: 2335035 05/01/1990       29 Citations
  • Mechanisms of pressure-induced myogenic activation of cerebral and renal arteries: role of the endothelium. (Harder DR, Kauser K, Roman RJ, Lombard JH) J Hypertens Suppl 1989 Sep;7(4):S11-5; discussion S16 PMID: 2809804 09/01/1989       22 Citations
  • Hemodynamics and microcirculatory alterations in reduced renal mass hypertension. (Lombard JH, Hinojosa-Laborde C, Cowley AW Jr) Hypertension 1989 Feb;13(2):128-38 PMID: 2914735 02/01/1989       63 Citations
  • Microvascular rarefaction and tissue vascular resistance in hypertension. (Greene AS, Tonellato PJ, Lui J, Lombard JH, Cowley AW Jr) Am J Physiol 1989 Jan;256(1 Pt 2):H126-31 PMID: 2912175 01/11/1989       197 Citations
  • Active tone and arteriolar responses to increased oxygen availability in the mesoappendix of spontaneously hypertensive rats. (Lombard JH, Stekiel WJ) Microcirc Endothelium Lymphatics 1988 Oct;4(5):339-53 PMID: 3244329 10/01/1988       3 Citations
  • Pressure-diuresis in volume-expanded rats. Cortical and medullary hemodynamics. (Roman RJ, Cowley AW Jr, Garcia-Estañ J, Lombard JH) Hypertension 1988 Aug;12(2):168-76 PMID: 3410525 08/01/1988       111 Citations
  • Vascular muscle cell depolarization and activation in renal arteries on elevation of transmural pressure. (Harder DR, Gilbert R, Lombard JH) Am J Physiol 1987 Oct;253(4 Pt 2):F778-81 PMID: 2444115 10/01/1987       119 Citations
  • Reduced electrogenic sodium-potassium pump in arterioles during renovascular hypertension. (Lombard JH, Joyner WL, Stekiel WJ) Hypertension 1987 Jun;9(6 Pt 2):III86-90 PMID: 2439454 06/01/1987       4 Citations
  • The effect of alkaline pH and transmural pressure on arterial constriction and membrane potential of hypertensive cerebral arteries. (Smeda JS, Lombard JH, Madden JA, Harder DR) Pflugers Arch 1987 Mar;408(3):239-42 PMID: 3106928 03/01/1987       18 Citations
  • Relationship between body fluid volumes and arterial pressure. (Cowley AW Jr, Barber WJ, Lombard JH, Osborn JL, Liard JF) Fed Proc 1986 Dec;45(13):2864-70 PMID: 3536582 12/01/1986       24 Citations
  • Evaluation of laser-Doppler flowmetry as a measure of tissue blood flow. (Smits GJ, Roman RJ, Lombard JH) J Appl Physiol (1985) 1986 Aug;61(2):666-72 PMID: 2943717 08/01/1986       165 Citations
  • Enhanced response of arterioles to oxygen during development of hypertension in SHR. (Lombard JH, Hess ME, Stekiel WJ) Am J Physiol 1986 May;250(5 Pt 2):H761-4 PMID: 3706551 05/01/1986       23 Citations
  • Effect of reduced oxygen availability upon myogenic depolarization and contraction of cat middle cerebral artery. (Lombard JH, Smeda J, Madden JA, Harder DR) Circ Res 1986 Apr;58(4):565-9 PMID: 3698219 04/01/1986       25 Citations
  • Small vessel membrane potential, sympathetic input, and electrogenic pump rate in SHR. (Stekiel WJ, Contney SJ, Lombard JH) Am J Physiol 1986 Apr;250(4 Pt 1):C547-56 PMID: 3008565 04/01/1986       42 Citations
  • Vascular smooth muscle transmembrane potentials during hypotensive stress. (Lombard JH, Willems WJ, Harder DR, Stekiel WJ) Circ Shock 1986;18(2):131-40 PMID: 3948338 01/01/1986       2 Citations
  • Effect of oxygen on arteriolar diameters in the rat mesoappendix. (Lombard JH, Stekiel WJ) Microvasc Res 1985 Nov;30(3):346-9 PMID: 4088096 11/01/1985       4 Citations
  • Nonneural vascular smooth muscle tone in arterioles of the hamster cheek pouch. (Lombard JH, Chenoweth JL, Stekiel WJ) Microvasc Res 1985 Jan;29(1):81-8 PMID: 3920480 01/01/1985       4 Citations
  • Neural and local control of arterioles in SHR. (Lombard JH, Hess ME, Stekiel WJ) Hypertension 1984 Jul-Aug;6(4):530-5 PMID: 6746085 07/01/1984       34 Citations
  • Role of vascular smooth muscle transmembrane potential in control of the microcirculation. (Lombard JH, Willems WJ, Stekiel WJ) Microcirc Endothelium Lymphatics 1984 Feb;1(1):25-55 PMID: 6152809 02/01/1984       1 Citations
  • Reduced venoconstrictor reserve in spontaneously hypertensive rats subjected to hemorrhagic stress. (Burke MJ, Stekiel WJ, Lombard JH) Circ Shock 1984;14(1):25-37 PMID: 6488480 01/01/1984       16 Citations
  • Response of venous membrane potentials to calcium blockade in spontaneous hypertension. (Stekiel WJ, Contney SJ, Lombard JH, Harder DR) Hypertension 1983 Mar-Apr;5(2 Pt 2):I64-9 PMID: 6826229 03/01/1983       1 Citations
  • Effect of methylprednisolone on small vein responses to hemorrhage and norepinephrine. (Harder DR, Stekiel WJ, Lombard JH) Eur J Pharmacol 1982 Jun 16;81(1):163-6 PMID: 7117368 06/16/1982       3 Citations
  • Effect of tetrodotoxin on membrane potentials and active tone in vascular smooth muscle. (Lombard JH, Burke MJ, Contney SJ, Willems WJ, Stekiel WJ) Am J Physiol 1982 Jun;242(6):H967-72 PMID: 7091357 06/01/1982       15 Citations
  • Multiple mechanisms of reactive hyperemia in arterioles of the hamster cheek pouch. (Lombard JH, Duling BR) Am J Physiol 1981 Nov;241(5):H748-55 PMID: 7304764 11/01/1981       23 Citations
  • Arteriolar responses to changes in oxygen availability following single withdrawal hemorrhage. (Lombard JH, Kaminski RP, Stekiel WJ) Microvasc Res 1981 May;21(3):332-42 PMID: 7242383 05/01/1981       8 Citations
  • Active vascular smooth muscle tone and venous membrane potentials during hemorrhage. (Stekiel WJ, Willems WJ, Harder DR, Lombard JH) Am J Physiol 1980 Feb;238(2):H144-52 PMID: 7361906 02/01/1980       5 Citations
  • Prevention by methylprednisolone of norepinephrine depletion in vascular tissue during severe hemorrhage in dogs. (Lombard JH, Loegering DJ, Stekiel WJ) Blood Vessels 1980;17(5):276-80 PMID: 7397411 01/01/1980       3 Citations
  • Relative importance of tissue oxygenation and vascular smooth muscle hypoxia in determining arteriolar responses to occlusion in the hamster cheek pouch. (Lombard JH, Duling BR) Circ Res 1977 Oct;41(4):546-51 PMID: 902360 10/01/1977       18 Citations
  • Relative contributions of passive and myogenic factors to diameter changes during single arteriole occlusion in the hamster cheek pouch. (Lombard JH, Duling BR) Circ Res 1977 Sep;41(3):365-73 PMID: 890891 09/01/1977       21 Citations
  • Effects of prolonged hemorrhagic hypotensive stress on catecholamine concentration of mesenteric blood vessels. (Lombard JH, Loegering DJ, Stekiel WJ) Blood Vessels 1977;14(4):212-28 PMID: 861382 01/01/1977       2 Citations
  • Last update: 02/07/2018
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