Medical College of Wisconsin
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Julie-An M. Talano MD

Julie-An M. Talano MD

Professor

Institution: Medical College of Wisconsin
Department: Pediatrics
Division: Hematology and Oncology - Pediatrics
Program: Oncology

Member of the Cancer Center


Research Experience

  • Bone Marrow Transplantation
  • Hematopoietic Stem Cell Transplantation
  • Lymphohistiocytosis, Hemophagocytic
  • Clinical Expertise

  • Bone Marrow Transplantation
  • Lymphohistiocytosis, Hemophagocytic
  • Publications (46)

  • Hemophagocytic lymphohistiocytosis mimicking neonatal hemochromatosis. (Broglie L, Vitola B, Thakar MS, Basel D, Szabo S, Agni R, Talano JA) Pediatr Hematol Oncol 2019 Oct;36(7):451-456 PMID: 31424295 SCOPUS ID: 2-s2.0-85071390624 08/20/2019    
  • First report that prior ECMO therapy does not preclude hematopoietic cell transplantation. (Broglie L, Phelan R, Talano JA) Pediatr Hematol Oncol 2018 May;35(4):245-249 PMID: 30570427 SCOPUS ID: 2-s2.0-85059008833 12/21/2018    
  • Post-transplantation employment status of adult survivors of childhood allogeneic hematopoietic cell transplant: A report from the Center for International Blood and Marrow Transplant Research (CIBMTR). (Bhatt NS, Brazauskas R, Tecca HR, Carreras J, Burns LJ, Phelan R, Salit RB, Syrjala KL, Talano JM, Shaw BE) Cancer 2019 01 01;125(1):144-152 PMID: 30368771 PMCID: PMC6310211 SCOPUS ID: 2-s2.0-85055708918 10/29/2018    
  • Reduced-intensity conditioning for hematopoietic cell transplant for HLH and primary immune deficiencies. (Allen CE, Marsh R, Dawson P, Bollard CM, Shenoy S, Roehrs P, Hanna R, Burroughs L, Kean L, Talano JA, Schultz KR, Pai SY, Baker KS, Andolina JR, Stenger EO, Connelly J, Ramirez A, Bryant C, Eapen M, Pulsipher MA) Blood 2018 09 27;132(13):1438-1451 PMID: 29997222 PMCID: PMC6161764 SCOPUS ID: 2-s2.0-85053908983 07/13/2018       8 Citations
  • Hemophagocytic lymphohistiocytosis in adults. (Bhatt NS, Oshrine B, An Talano J) Leuk Lymphoma 2019 01;60(1):19-28 PMID: 29966474 SCOPUS ID: 2-s2.0-85061376634 07/04/2018       1 Citation
  • Outcomes of Measurable Residual Disease in Pediatric Acute Myeloid Leukemia before and after Hematopoietic Stem Cell Transplant: Validation of Difference from Normal Flow Cytometry with Chimerism Studies and Wilms Tumor 1 Gene Expression. (Jacobsohn DA, Loken MR, Fei M, Adams A, Brodersen LE, Logan BR, Ahn KW, Shaw BE, Kletzel M, Olszewski M, Khan S, Meshinchi S, Keating A, Harris A, Teira P, Duerst RE, Margossian SP, Martin PL, Petrovic A, Dvorak CC, Nemecek ER, Boyer MW, Chen AR, Davis JH, Shenoy S, Savasan S, Hudspeth MP, Adams RH, Lewis VA, Kheradpour A, Kasow KA, Gillio AP, Haight AE, Bhatia M, Bambach BJ, Haines HL, Quigg TC, Greiner RJ, Talano JM, Delgado DC, Cheerva A, Gowda M, Ahuja S, Ozkaynak M, Mitchell D, Schultz KR, Fry TJ, Loeb DM, Pulsipher MA) Biol Blood Marrow Transplant 2018 10;24(10):2040-2046 PMID: 29933069 PMCID: PMC6239928 SCOPUS ID: 2-s2.0-85050818070 06/23/2018       8 Citations
  • The safety and efficacy of clofarabine in combination with high-dose cytarabine and total body irradiation myeloablative conditioning and allogeneic stem cell transplantation in children, adolescents, and young adults (CAYA) with poor-risk acute leukemia. (Hochberg J, Zahler S, Geyer MB, Chen N, Krajewski J, Harrison L, Militano O, Ozkaynak MF, Cheerva AC, Talano J, Moore TB, Gillio AP, Walters MC, Baxter-Lowe LA, Hamby C, Cairo MS) Bone Marrow Transplant 2019 02;54(2):226-235 PMID: 29899571 SCOPUS ID: 2-s2.0-85048460040 06/15/2018       1 Citation
  • Treosulfan, Fludarabine, and Low-Dose Total Body Irradiation for Children and Young Adults with Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Allogeneic Hematopoietic Cell Transplantation: Prospective Phase II Trial of the Pediatric Blood and Marrow Transplant Consortium. (Nemecek ER, Hilger RA, Adams A, Shaw BE, Kiefer D, Le-Rademacher J, Levine JE, Yanik G, Leung W, Talano JA, Haut P, Delgado D, Kapoor N, Petrovic A, Adams R, Hanna R, Rangarajan H, Dalal J, Chewning J, Verneris MR, Epstein S, Burroughs L, Perez-Albuerne ED, Pulsipher MA, Delaney C) Biol Blood Marrow Transplant 2018 08;24(8):1651-1656 PMID: 29753157 PMCID: PMC6108922 SCOPUS ID: 2-s2.0-85047460893 05/13/2018       2 Citations
  • Allogeneic Hematopoietic Cell Transplantation for Chronic Granulomatous Disease: Controversies and State of the Art. (Connelly JA, Marsh R, Parikh S, Talano JA) J Pediatric Infect Dis Soc 2018 May 09;7(suppl_1):S31-S39 PMID: 29746680 PMCID: PMC5946867 SCOPUS ID: 2-s2.0-85048642626 05/11/2018       6 Citations
  • Late cardiovascular morbidity and mortality following pediatric allogeneic hematopoietic cell transplantation. (Duncan CN, Brazauskas R, Huang J, Shaw BE, Majhail NS, Savani BN, Flowers MED, Battiwalla M, Beebe K, Dietz AC, Dvorak CC, Giller R, Jacobsohn DA, Kletzel M, Martin PL, Nemecek ER, Nuechterlein B, Talano JA, Pulsipher MA, Baker KS) Bone Marrow Transplant 2018 10;53(10):1278-1287 PMID: 29581480 PMCID: PMC6158112 SCOPUS ID: 2-s2.0-85044469262 03/28/2018       5 Citations
  • Ruxolitinib for treatment of refractory hemophagocytic lymphohistiocytosis. (Broglie L, Pommert L, Rao S, Thakar M, Phelan R, Margolis D, Talano J) Blood Adv 2017 Aug 22;1(19):1533-1536 PMID: 29296794 PMCID: PMC5728466 SCOPUS ID: 2-s2.0-85040141428 01/04/2018    
  • Allogeneic Hematopoietic Cell Transplantation Using Treosulfan-Based Conditioning for Treatment of Marrow Failure Disorders. (Burroughs LM, Shimamura A, Talano JA, Domm JA, Baker KK, Delaney C, Frangoul H, Margolis DA, Baker KS, Nemecek ER, Geddis AE, Sandmaier BM, Deeg HJ, Storb R, Woolfrey AE) Biol Blood Marrow Transplant 2017 Oct;23(10):1669-1677 PMID: 28602958 PMCID: PMC5605451 SCOPUS ID: 2-s2.0-85025429864 06/13/2017       12 Citations
  • Usual and Unusual Manifestations of Familial Hemophagocytic Lymphohistiocytosis and Langerhans Cell Histiocytosis. (Erker C, Harker-Murray P, Talano JA) Pediatr Clin North Am 2017 Feb;64(1):91-109 PMID: 27894453 SCOPUS ID: 2-s2.0-84998773661 11/30/2016       3 Citations
  • Salvage therapy for refractory hemophagocytic lymphohistiocytosis: A review of the published experience. (Marsh RA, Jordan MB, Talano JA, Nichols KE, Kumar A, Naqvi A, Vaiselbuh SR, Histiocyte Society Salvage Therapy Working Group) Pediatr Blood Cancer 2017 04;64(4) PMID: 27786410 SCOPUS ID: 2-s2.0-84999791337 10/28/2016       13 Citations
  • Successful treatment of recurrent CNS disease post-bone marrow transplant in children with familial hemophagocytic lymphohistiocytosis. (Bock AM, LeVeque M, Camitta B, Talano JA) Pediatr Blood Cancer 2016 12;63(12):2154-2158 PMID: 27565627 SCOPUS ID: 2-s2.0-84983551835 10/21/2016       3 Citations
  • Treosulfan-based conditioning for allogeneic HSCT in children with chronic granulomatous disease: a multicenter experience. (Morillo-Gutierrez B, Beier R, Rao K, Burroughs L, Schulz A, Ewins AM, Gibson B, Sedlacek P, Krol L, Strahm B, Zaidman I, Kalwak K, Talano JA, Woolfrey A, Fraser C, Meyts I, Müller I, Wachowiak J, Bernardo ME, Veys P, Sykora KW, Gennery AR, Slatter M) Blood 2016 07 21;128(3):440-8 PMID: 27216217 PMCID: PMC4957165 SCOPUS ID: 2-s2.0-84979529945 05/25/2016       48 Citations
  • Curative treatment for severe sickle cell disease: allogeneic transplantation. (Oshrine B, Talano JA) Clin Adv Hematol Oncol 2015 Apr;13(4):249-56 PMID: 26352583 SCOPUS ID: 2-s2.0-84926621177 09/10/2015       1 Citation
  • Transplant Outcomes for Children with T Cell Acute Lymphoblastic Leukemia in Second Remission: A Report from the Center for International Blood and Marrow Transplant Research. (Burke MJ, Verneris MR, Le Rademacher J, He W, Abdel-Azim H, Abraham AA, Auletta JJ, Ayas M, Brown VI, Cairo MS, Chan KW, Diaz Perez MA, Dvorak CC, Egeler RM, Eldjerou L, Frangoul H, Guilcher GMT, Hayashi RJ, Ibrahim A, Kasow KA, Leung WH, Olsson RF, Pulsipher MA, Shah N, Shah NN, Thiel E, Talano JA, Kitko CL) Biol Blood Marrow Transplant 2015 Dec;21(12):2154-2159 PMID: 26327632 PMCID: PMC4654112 SCOPUS ID: 2-s2.0-84947443750 09/04/2015       8 Citations
  • Smoothing the crescent curve: sickle cell disease. (Talano JA, Cairo MS) Hematology Am Soc Hematol Educ Program 2014 Dec 05;2014(1):468-74 PMID: 25696896 SCOPUS ID: 2-s2.0-84937575445 02/20/2015       2 Citations
  • Hematopoietic stem cell transplantation for sickle cell disease: state of the science. (Talano JA, Cairo MS) Eur J Haematol 2015 May;94(5):391-9 PMID: 25200500 SCOPUS ID: 2-s2.0-84926509714 09/10/2014       14 Citations
  • Treosulfan-based conditioning and hematopoietic cell transplantation for nonmalignant diseases: a prospective multicenter trial. (Burroughs LM, Nemecek ER, Torgerson TR, Storer BE, Talano JA, Domm J, Giller RH, Shimamura A, Delaney C, Skoda-Smith S, Thakar MS, Baker KS, Rawlings DJ, Englund JA, Flowers ME, Deeg HJ, Storb R, Woolfrey AE) Biol Blood Marrow Transplant 2014 Dec;20(12):1996-2003 PMID: 25196857 PMCID: PMC4324724 SCOPUS ID: 2-s2.0-84912123151 09/10/2014       24 Citations
  • Sequential myeloablative autologous stem cell transplantation and reduced intensity allogeneic hematopoietic cell transplantation is safe and feasible in children, adolescents and young adults with poor-risk refractory or recurrent Hodgkin and non-Hodgkin lymphoma. (Satwani P, Jin Z, Martin PL, Bhatia M, Garvin JH, George D, Chaudhury S, Talano J, Morris E, Harrison L, Sosna J, Peterson M, Militano O, Foley S, Kurtzberg J, Cairo MS) Leukemia 2015 Feb;29(2):448-55 PMID: 24938649 SCOPUS ID: 2-s2.0-84922470679 06/19/2014       25 Citations
  • New frontiers in pediatric Allo-SCT. (Talano JM, Pulsipher MA, Symons HJ, Militano O, Shereck EB, Giller RH, Hancock L, Morris E, Cairo MS) Bone Marrow Transplant 2014 Sep;49(9):1139-45 PMID: 24820213 PMCID: PMC4439009 05/14/2014       4 Citations
  • Indications for transplantation in childhood acute leukemia and the impact of minimal residual disease on relapse: A review (Thakar MS, Talano JAM, Tower RL, Kelly ME, Burke MJ) Clinical Practice January 2014;11(1):79-90 SCOPUS ID: 2-s2.0-84896522397 01/01/2014    
  • Allogeneic human mesenchymal stem cell therapy (remestemcel-L, Prochymal) as a rescue agent for severe refractory acute graft-versus-host disease in pediatric patients. (Kurtzberg J, Prockop S, Teira P, Bittencourt H, Lewis V, Chan KW, Horn B, Yu L, Talano JA, Nemecek E, Mills CR, Chaudhury S) Biol Blood Marrow Transplant 2014 Feb;20(2):229-35 PMID: 24216185 SCOPUS ID: 2-s2.0-84893106561 11/13/2013       88 Citations
  • The use of novel Therakos™ Cellex® for extracorporeal photopheresis in treatment of graft-versus-host disease in paediatric patients. (Rangarajan HG, Punzalan RC, Camitta BM, Talano JA) Br J Haematol 2013 Nov;163(3):357-64 PMID: 23961954 SCOPUS ID: 2-s2.0-84885418957 08/22/2013       12 Citations
  • Treatment of Epstein Barr virus-induced haemophagocytic lymphohistiocytosis with rituximab-containing chemo-immunotherapeutic regimens. (Chellapandian D, Das R, Zelley K, Wiener SJ, Zhao H, Teachey DT, Nichols KE, EBV-HLH Rituximab Study Group) Br J Haematol 2013 Aug;162(3):376-82 PMID: 23692048 PMCID: PMC3776423 05/23/2013       84 Citations
  • Clinical outcomes of children receiving intensive cardiopulmonary support during hematopoietic stem cell transplant. (Duncan CN, Lehmann LE, Cheifetz IM, Greathouse K, Haight AE, Hall MW, Herschberger A, Hill KS, Moffet JR, Morrison RR, Norris AL, Petrovic A, Spear DA, Steiner ME, Talano JA, Tamburro RF, Wagner J, McArthur J, Pediatric Acute Lung Injury and Sepsis (PALISI) Network) Pediatr Crit Care Med 2013 Mar;14(3):261-7 PMID: 23392372 SCOPUS ID: 2-s2.0-84874940076 02/09/2013       29 Citations
  • Monitoring and prevention of relapse after allogeneic hematopoietic cell transplantation for myeloid malignancies. (Bacher U, Talano JA, Bishop MR) Biol Blood Marrow Transplant 2012 Jan;18(1 Suppl):S62-73 PMID: 22226115 SCOPUS ID: 2-s2.0-84855410095 01/18/2012       15 Citations
  • Allogeneic cellular and autologous stem cell therapy for sickle cell disease: 'whom, when and how'. (Freed J, Talano J, Small T, Ricci A, Cairo MS) Bone Marrow Transplant 2012 Dec;47(12):1489-98 PMID: 22179556 SCOPUS ID: 2-s2.0-84870804411 12/20/2011       11 Citations
  • Critical Illness Involving Children Undergoing Hematopoietic Progenitor Cell Transplantation (McArthur JA, Bambach B, Duncan C, Talano JA, Tamburro RT) Pediatric Critical Care 2011:1177-1190 SCOPUS ID: 2-s2.0-84884434163 12/01/2011    
  • Treatment of recurrent CNS disease post-bone marrow transplant in familial HLH. (Rangarajan HG, Grochowski D, Mulberry MF, Gheorghe G, Camitta BM, Talano JA) Pediatr Blood Cancer 2012 Jul 15;59(1):189-90 PMID: 21755594 SCOPUS ID: 2-s2.0-84861218979 07/15/2011       2 Citations
  • Association of Crohn's disease, thiopurines, and primary epstein-barr virus infection with hemophagocytic lymphohistiocytosis. (Biank VF, Sheth MK, Talano J, Margolis D, Simpson P, Kugathasan S, Stephens M) J Pediatr 2011 Nov;159(5):808-12 PMID: 21722918 PMCID: PMC3191286 SCOPUS ID: 2-s2.0-80054753242 07/05/2011       43 Citations
  • Delayed hemolytic transfusion reaction in children with sickle cell disease. (de Montalembert M, Dumont MD, Heilbronner C, Brousse V, Charrara O, Pellegrino B, Piguet C, Soussan V, Noizat-Pirenne F) Haematologica 2011 Jun;96(6):801-7 PMID: 21330322 PMCID: PMC3105640 02/19/2011       51 Citations
  • Efficacy and safety of ex vivo cultured adult human mesenchymal stem cells (Prochymal™) in pediatric patients with severe refractory acute graft-versus-host disease in a compassionate use study. (Prasad VK, Lucas KG, Kleiner GI, Talano JA, Jacobsohn D, Broadwater G, Monroy R, Kurtzberg J) Biol Blood Marrow Transplant 2011 Apr;17(4):534-41 PMID: 20457269 SCOPUS ID: 2-s2.0-79952624644 05/12/2010       192 Citations
  • Focal nodular hyperplasia in pediatric allogeneic hematopoietic cell transplant: case series. (Anderson L, Gregg D, Margolis D, Casper J, Talano J) Bone Marrow Transplant 2010 Aug;45(8):1357-9 PMID: 20140023 SCOPUS ID: 2-s2.0-77955561931 02/09/2010       14 Citations
  • Antiviral responses following L-leucyl-L-leucine methyl esther (LLME)-treated lymphocyte infusions: graft-versus-infection without graft-versus-host disease. (Filicko-O'Hara J, Grosso D, Flomenberg PR, Friedman TM, Brunner J, Drobyski W, Ferber A, Kakhniashvili I, Keever-Taylor C, Mookerjee B, Talano JA, Wagner JI, Korngold R, Flomenberg N) Biol Blood Marrow Transplant 2009 Dec;15(12):1609-19 PMID: 19744572 PMCID: PMC2783272 SCOPUS ID: 2-s2.0-70350459268 09/12/2009       6 Citations
  • Hematopoietic Cell Transplantation for Childhood Acute Myeloid Leukemia (Talano JAM, Casper JT, Margolis DA) Thomas' Hematopoietic Cell Transplantation: Stem Cell Transplantation, Fourth Edition 5 March 2009:775-790 SCOPUS ID: 2-s2.0-84890702087 03/05/2009    
  • Severe hypercholesterolemia mediated by lipoprotein X in a pediatric patient with chronic graft-versus-host disease of the liver. (Zidan H, Lo S, Wiebe D, Talano J, Alemzadeh R) Pediatr Blood Cancer 2008 Jun;50(6):1280-1 PMID: 18286546 SCOPUS ID: 2-s2.0-42349086297 02/21/2008       12 Citations
  • Voriconazole-induced blistering in the setting of graft versus host disease: A report of 2 patients. (Conlon JD, Dauenhauer M, Tonkovic-Capin V, Talano J, Margolis D, Drolet BA, Fairley JA) J Am Acad Dermatol 2008 Mar;58(3):484-7 PMID: 18280346 SCOPUS ID: 2-s2.0-38949186469 02/19/2008       9 Citations
  • Captopril to mitigate chronic renal failure after hematopoietic stem cell transplantation: a randomized controlled trial. (Cohen EP, Irving AA, Drobyski WR, Klein JP, Passweg J, Talano JA, Juckett MB, Moulder JE) Int J Radiat Oncol Biol Phys 2008 Apr 01;70(5):1546-51 PMID: 18029109 PMCID: PMC2386758 SCOPUS ID: 2-s2.0-40949138809 11/22/2007       53 Citations
  • Recent molecular and cellular advances in pediatric bone marrow transplantation. (Talano JA, Margolis DA) Pediatr Clin North Am 2006 Aug;53(4):685-98 PMID: 16872999 SCOPUS ID: 2-s2.0-33746253782 07/29/2006       2 Citations
  • Alternative donor bone marrow transplant for children with Philadelphia chromosome ALL. (Talano JM, Casper JT, Camitta BM, Keever-Taylor CA, Murray KJ, Eapen M, Pierce KL, Margolis DA) Bone Marrow Transplant 2006 Jan;37(2):135-41 PMID: 16273115 SCOPUS ID: 2-s2.0-30944438521 11/08/2005       13 Citations
  • Delayed hemolytic transfusion reaction/hyperhemolysis syndrome in children with sickle cell disease. (Talano JA, Hillery CA, Gottschall JL, Baylerian DM, Scott JP) Pediatrics 2003 Jun;111(6 Pt 1):e661-5 PMID: 12777582 SCOPUS ID: 2-s2.0-17344391561 06/05/2003       121 Citations
  • Long-term follow-up of children with fever of unknown origin. (Talano JA, Katz BZ) Clin Pediatr (Phila) 2000 Dec;39(12):715-7 PMID: 11156069 SCOPUS ID: 2-s2.0-0034541851 01/13/2001       15 Citations
  • Inhibition of human type IV collagenase by a highly conserved peptide sequence derived from its prosegment. (Stetler-Stevenson WG, Talano JA, Gallagher ME, Krutzsch HC, Liotta LA) Am J Med Sci 1991 Sep;302(3):163-70 PMID: 1656751 09/01/1991       32 Citations
  • Last update: 11/01/2019
    jenkins-FCD Prod-398 336d56a365602aa89dcc112f077233607d6a5abc