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Kathleen M. Schmainda PhD

Professor

Institution: Medical College of Wisconsin
Department: Biophysics
Program: Administration

Member of the Cancer Center
Member of the Center for Disease Prevention Research (CDPR)
Member of the Neuroscience Research Center

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Publications (120)

Application of Delta T1 maps for quantitative and objective assessment of extent of resection and survival prediction in glioblastoma. (Laing BR, Prah MA, Best BJ, Krucoff MO, Mueller WM, Schmainda KM) Neurosurg Pract 2024 Mar;5(1) PMID: 38919518 PMCID: PMC11198967 06/26/2024

Identification of a Single-Dose, Low-Flip-Angle-Based CBV Threshold for Fractional Tumor Burden Mapping in Recurrent Glioblastoma. (Anil A, Stokes AM, Karis JP, Bell LC, Eschbacher J, Jennings K, Prah MA, Hu LS, Boxerman JL, Schmainda KM, Quarles CC) AJNR Am J Neuroradiol 2024 Sep 05 PMID: 38782593 05/24/2024

Practical guidance to identify and troubleshoot suboptimal DSC-MRI results. (Prah MA, Schmainda KM) Front Radiol 2024;4:1307586 PMID: 38445104 PMCID: PMC10913595 SCOPUS ID: 2-s2.0-85186888913 03/06/2024

Potent in vivo efficacy of oral gallium maltolate in treatment-resistant glioblastoma. (Al-Gizawiy MM, Wujek RT, Alhajala HS, Cobb JM, Prah MA, Doan NB, Connelly JM, Chitambar CR, Schmainda KM) Front Oncol 2023;13:1278157 PMID: 38288102 PMCID: PMC10822938 SCOPUS ID: 2-s2.0-85183616626 01/30/2024 1 Citation

Magnetic resonance imaging-derived relative cerebral blood volume characteristics in a case of pathologically confirmed neurocysticercosis: illustrative case. (Botros NE, Polinger-Hyman D, Beck RT, Kleefisch C, Mrachek EKS, Connelly J, Schmainda KM, Krucoff MO) J Neurosurg Case Lessons 2023 Dec 18;6(25) PMID: 38109728 PMCID: PMC10732321 SCOPUS ID: 2-s2.0-85185333375 12/18/2023

A cross-sectional study to test equivalence of low- versus intermediate-flip angle dynamic susceptibility contrast MRI measures of relative cerebral blood volume in patients with high-grade gliomas at 1.5 Tesla field strength. (Shiroishi MS, Weinert D, Cen SY, Varghese B, Dondlinger T, Prah M, Mendoza J, Nazemi S, Ameli N, Amini N, Shohas S, Chen S, Bigjahan B, Zada G, Chen T, Neman-Ebrahim J, Chang EL, Chow FE, Fan Z, Yang W, Attenello FJ, Ye J, Kim PE, Patel VN, Lerner A, Acharya J, Hu LS, Quarles CC, Boxerman JL, Wu O, Schmainda KM) Front Oncol 2023;13:1156843 PMID: 37799462 PMCID: PMC10548232 SCOPUS ID: 2-s2.0-85173923983 10/06/2023 1 Citation

Integrated molecular and multiparametric MRI mapping of high-grade glioma identifies regional biologic signatures. (Hu LS, D'Angelo F, Weiskittel TM, Caruso FP, Fortin Ensign SP, Blomquist MR, Flick MJ, Wang L, Sereduk CP, Meng-Lin K, De Leon G, Nespodzany A, Urcuyo JC, Gonzales AC, Curtin L, Lewis EM, Singleton KW, Dondlinger T, Anil A, Semmineh NB, Noviello T, Patel RA, Wang P, Wang J, Eschbacher JM, Hawkins-Daarud A, Jackson PR, Grunfeld IS, Elrod C, Mazza GL, McGee SC, Paulson L, Clark-Swanson K, Lassiter-Morris Y, Smith KA, Nakaji P, Bendok BR, Zimmerman RS, Krishna C, Patra DP, Patel NP, Lyons M, Neal M, Donev K, Mrugala MM, Porter AB, Beeman SC, Jensen TR, Schmainda KM, Zhou Y, Baxter LC, Plaisier CL, Li J, Li H, Lasorella A, Quarles CC, Swanson KR, Ceccarelli M, Iavarone A, Tran NL) Nat Commun 2023 Sep 28;14(1):6066 PMID: 37770427 PMCID: PMC10539500 SCOPUS ID: 2-s2.0-85172828207 09/29/2023 7 Citations

Advanced MR Techniques for Preoperative Glioma Characterization: Part 2. (Hangel G, Schmitz-Abecassis B, Sollmann N, Pinto J, Arzanforoosh F, Barkhof F, Booth T, Calvo-Imirizaldu M, Cassia G, Chmelik M, Clement P, Ercan E, Fernández-Seara MA, Furtner J, Fuster-Garcia E, Grech-Sollars M, Guven NT, Hatay GH, Karami G, Keil VC, Kim M, Koekkoek JAF, Kukran S, Mancini L, Nechifor RE, Özcan A, Ozturk-Isik E, Piskin S, Schmainda KM, Svensson SF, Tseng CH, Unnikrishnan S, Vos F, Warnert E, Zhao MY, Jancalek R, Nunes T, Hirschler L, Smits M, Petr J, Emblem KE) J Magn Reson Imaging 2023 Jun;57(6):1676-1695 PMID: 36912262 PMCID: PMC10947037 SCOPUS ID: 2-s2.0-85150601586 03/14/2023 17 Citations

Early post-bevacizumab change in rCBV from DSC-MRI identifies pseudoresponse in recurrent glioblastoma: Results from ACRIN 6677/RTOG 0625. (Boxerman JL, Snyder BS, Barboriak DP, Schmainda KM) Front Oncol 2023;13:1061502 PMID: 36776298 PMCID: PMC9909012 SCOPUS ID: 2-s2.0-85147689993 02/14/2023 2 Citations

A cross-sectional study to test equivalence of low- versus intermediate-flip angle dynamic susceptibility contrast MRI measures of relative cerebral blood volume in patients with high-grade gliomas at 1.5 Tesla field strength (Shiroishi MS, Weinert D, Cen SY, Varghese B, Dondlinger T, Prah M, Mendoza J, Nazemi S, Ameli N, Amini N, Shohas S, Chen S, Bigjahan B, Zada G, Chen T, Neman-Ebrahim J, Chang EL, Chow FE, Fan Z, Yang W, Attenello FJ, Ye J, Kim PE, Patel VN, Lerner A, Acharya J, Hu LS, Quarles CC, Boxerman JL, Wu O, Schmainda KM) Frontiers in Oncology 2023;13 SCOPUS ID: 2-s2.0-85173923983 01/01/2023 1 Citation

Case report: Fractional brain tumor burden magnetic resonance mapping to assess response to pulsed low-dose-rate radiotherapy in newly-diagnosed glioblastoma. (Amidon RF, Santos-Pinheiro F, Straza M, Prah MA, Mueller WM, Krucoff MO, Connelly JM, Kleefisch CJ, Coss DJ, Cochran EJ, Bovi JA, Schultz CJ, Schmainda KM) Front Oncol 2022;12:1066191 PMID: 36561526 PMCID: PMC9763264 SCOPUS ID: 2-s2.0-85144231369 12/24/2022

Advanced MRI Protocols to Discriminate Glioma From Treatment Effects: State of the Art and Future Directions. (Malik DG, Rath TJ, Urcuyo Acevedo JC, Canoll PD, Swanson KR, Boxerman JL, Quarles CC, Schmainda KM, Burns TC, Hu LS) Front Radiol 2022;2:809373 PMID: 37492687 PMCID: PMC10365126 SCOPUS ID: 2-s2.0-85133003459 04/15/2022 4 Citations

High-Grade Glioma Treatment Response Monitoring Biomarkers: A Position Statement on the Evidence Supporting the Use of Advanced MRI Techniques in the Clinic, and the Latest Bench-to-Bedside Developments. Part 1: Perfusion and Diffusion Techniques. (Henriksen OM, Del Mar Álvarez-Torres M, Figueiredo P, Hangel G, Keil VC, Nechifor RE, Riemer F, Schmainda KM, Warnert EAH, Wiegers EC, Booth TC) Front Oncol 2022;12:810263 PMID: 35359414 PMCID: PMC8961422 SCOPUS ID: 2-s2.0-85130752094 04/02/2022 36 Citations

High-Grade Glioma Treatment Response Monitoring Biomarkers: A Position Statement on the Evidence Supporting the Use of Advanced MRI Techniques in the Clinic, and the Latest Bench-to-Bedside Developments. Part 2: Spectroscopy, Chemical Exchange Saturation, Multiparametric Imaging, and Radiomics. (Booth TC, Wiegers EC, Warnert EAH, Schmainda KM, Riemer F, Nechifor RE, Keil VC, Hangel G, Figueiredo P, Álvarez-Torres MDM, Henriksen OM) Front Oncol 2021;11:811425 PMID: 35340697 PMCID: PMC8948428 SCOPUS ID: 2-s2.0-85130696453 03/29/2022 17 Citations

Basal Ganglia Iron Content Increases with Glioma Severity Using Quantitative Susceptibility Mapping: A Potential Biomarker of Tumor Severity. (Reith TP, Prah MA, Choi EJ, Lee J, Wujek R, Al-Gizawiy M, Chitambar CR, Connelly JM, Schmainda KM) Tomography 2022 Mar 15;8(2):789-797 PMID: 35314642 PMCID: PMC8938779 SCOPUS ID: 2-s2.0-85126905772 03/23/2022 5 Citations

Perfusion magnetic resonance imaging for brain tumour characterisation and assessment of treatment response (Schmainda KM) Handbook of Neuro-Oncology Neuroimaging 1 January 2022:395-414 SCOPUS ID: 2-s2.0-85159028601 01/01/2022

Multi-Site Concordance of Diffusion-Weighted Imaging Quantification for Assessing Prostate Cancer Aggressiveness. (McGarry SD, Brehler M, Bukowy JD, Lowman AK, Bobholz SA, Duenweg SR, Banerjee A, Hurrell SL, Malyarenko D, Chenevert TL, Cao Y, Li Y, You D, Fedorov A, Bell LC, Quarles CC, Prah MA, Schmainda KM, Taouli B, LoCastro E, Mazaheri Y, Shukla-Dave A, Yankeelov TE, Hormuth DA 2nd, Madhuranthakam AJ, Hulsey K, Li K, Huang W, Huang W, Muzi M, Jacobs MA, Solaiyappan M, Hectors S, Antic T, Paner GP, Palangmonthip W, Jacobsohn K, Hohenwalter M, Duvnjak P, Griffin M, See W, Nevalainen MT, Iczkowski KA, LaViolette PS) J Magn Reson Imaging 2022 Jun;55(6):1745-1758 PMID: 34767682 PMCID: PMC9095769 SCOPUS ID: 2-s2.0-85118887092 11/13/2021 9 Citations

Magnetic Resonance Imaging Mapping of Brain Tumor Burden: Clinical Implications for Neurosurgical Management: Case Report. (Connelly JM, Prah MA, Santos-Pinheiro F, Mueller W, Cochran E, Schmainda KM) Neurosurg Open 2021 Dec;2(4):okab029 PMID: 34661110 PMCID: PMC8508085 10/19/2021

Human Fetal Tissue from Elective Abortions in Research and Medicine: Science, Ethics, and the Law. (Lee TS, Feeney MB, Schmainda KM, Sherley JL, Prentice DA) Issues Law Med 2020;35(1):3-61 PMID: 33950608 SCOPUS ID: 2-s2.0-85105541954 05/06/2021 2 Citations

Assessment of tumor hypoxia and perfusion in recurrent glioblastoma following bevacizumab failure using MRI and ¹⁸F-FMISO PET. (Huang S, Michalek JE, Reardon DA, Wen PY, Floyd JR, Fox PT, Clarke GD, Jerabek PA, Schmainda KM, Muzi M, Hyun H, Lee EQ, Brenner AJ) Sci Rep 2021 Apr 07;11(1):7632 PMID: 33828310 PMCID: PMC8027395 SCOPUS ID: 2-s2.0-85104042152 04/09/2021 16 Citations

Value of dynamic contrast perfusion MRI to predict early response to bevacizumab in newly diagnosed glioblastoma: results from ACRIN 6686 multicenter trial. (Schmainda KM, Prah MA, Marques H, Kim E, Barboriak DP, Boxerman JL) Neuro Oncol 2021 Feb 25;23(2):314-323 PMID: 32678438 PMCID: PMC7906067 SCOPUS ID: 2-s2.0-85102322282 07/18/2020 16 Citations

Pulsed Reduced Dose Rate Radiotherapy in Conjunction With Bevacizumab or Bevacizumab Alone in Recurrent High-grade Glioma: Survival Outcomes. (Bovi JA, Prah MA, Retzlaff AA, Schmainda KM, Connelly JM, Rand SD, Marszalkowski CS, Mueller WM, Siker ML, Schultz CJ) Int J Radiat Oncol Biol Phys 2020 Nov 15;108(4):979-986 PMID: 32599030 PMCID: PMC8655709 SCOPUS ID: 2-s2.0-85089292279 07/01/2020 16 Citations

Evaluating the Use of rCBV as a Tumor Grade and Treatment Response Classifier Across NCI Quantitative Imaging Network Sites: Part II of the DSC-MRI Digital Reference Object (DRO) Challenge. (Bell LC, Semmineh N, An H, Eldeniz C, Wahl R, Schmainda KM, Prah MA, Erickson BJ, Korfiatis P, Wu C, Sorace AG, Yankeelov TE, Rutledge N, Chenevert TL, Malyarenko D, Liu Y, Brenner A, Hu LS, Zhou Y, Boxerman JL, Yen YF, Kalpathy-Cramer J, Beers AL, Muzi M, Madhuranthakam AJ, Pinho M, Johnson B, Quarles CC) Tomography 2020 Jun;6(2):203-208 PMID: 32548297 PMCID: PMC7289259 SCOPUS ID: 2-s2.0-85086686948 06/18/2020 11 Citations

Consensus recommendations for a dynamic susceptibility contrast MRI protocol for use in high-grade gliomas. (Boxerman JL, Quarles CC, Hu LS, Erickson BJ, Gerstner ER, Smits M, Kaufmann TJ, Barboriak DP, Huang RH, Wick W, Weller M, Galanis E, Kalpathy-Cramer J, Shankar L, Jacobs P, Chung C, van den Bent MJ, Chang S, Al Yung WK, Cloughesy TF, Wen PY, Gilbert MR, Rosen BR, Ellingson BM, Schmainda KM, Jumpstarting Brain Tumor Drug Development Coalition Imaging Standardization Steering Committee) Neuro Oncol 2020 Sep 29;22(9):1262-1275 PMID: 32516388 PMCID: PMC7523451 SCOPUS ID: 2-s2.0-85092332195 06/10/2020 117 Citations

The cytotoxicity of gallium maltolate in glioblastoma cells is enhanced by metformin through combined action on mitochondrial complex 1. (Alhajala HS, Markley JL, Kim JH, Al-Gizawiy MM, Schmainda KM, Kuo JS, Chitambar CR) Oncotarget 2020 Apr 28;11(17):1531-1544 PMID: 32391122 PMCID: PMC7197450 SCOPUS ID: 2-s2.0-85086103488 05/12/2020 7 Citations

Magnolia extract is effective for the chemoprevention of oral cancer through its ability to inhibit mitochondrial respiration at complex I. (Zhang Q, Cheng G, Pan J, Zielonka J, Xiong D, Myers CR, Feng L, Shin SS, Kim YH, Bui D, Hu M, Bennett B, Schmainda K, Wang Y, Kalyanaraman B, You M) Cell Commun Signal 2020 Apr 07;18(1):58 PMID: 32264893 PMCID: PMC7140380 SCOPUS ID: 2-s2.0-85083071315 04/09/2020 19 Citations

Performance of Standardized Relative CBV for Quantifying Regional Histologic Tumor Burden in Recurrent High-Grade Glioma: Comparison against Normalized Relative CBV Using Image-Localized Stereotactic Biopsies. (Hoxworth JM, Eschbacher JM, Gonzales AC, Singleton KW, Leon GD, Smith KA, Stokes AM, Zhou Y, Mazza GL, Porter AB, Mrugala MM, Zimmerman RS, Bendok BR, Patra DP, Krishna C, Boxerman JL, Baxter LC, Swanson KR, Quarles CC, Schmainda KM, Hu LS) AJNR Am J Neuroradiol 2020 Mar;41(3):408-415 PMID: 32165359 PMCID: PMC7077911 SCOPUS ID: 2-s2.0-85082097097 03/14/2020 19 Citations

Quantitative Delta T1 (dT1) as a Replacement for Adjudicated Central Reader Analysis of Contrast-Enhancing Tumor Burden: A Subanalysis of the American College of Radiology Imaging Network 6677/Radiation Therapy Oncology Group 0625 Multicenter Brain Tumor Trial. (Schmainda KM, Prah MA, Zhang Z, Snyder BS, Rand SD, Jensen TR, Barboriak DP, Boxerman JL) AJNR Am J Neuroradiol 2019 Jul;40(7):1132-1139 PMID: 31248863 PMCID: PMC6620020 SCOPUS ID: 2-s2.0-85069294543 06/30/2019 15 Citations

Moving Toward a Consensus DSC-MRI Protocol: Validation of a Low-Flip Angle Single-Dose Option as a Reference Standard for Brain Tumors. (Schmainda KM, Prah MA, Hu LS, Quarles CC, Semmineh N, Rand SD, Connelly JM, Anderies B, Zhou Y, Liu Y, Logan B, Stokes A, Baird G, Boxerman JL) AJNR Am J Neuroradiol 2019 Apr;40(4):626-633 PMID: 30923088 PMCID: PMC6461489 SCOPUS ID: 2-s2.0-85064588009 03/30/2019 33 Citations

Evaluating Multisite rCBV Consistency from DSC-MRI Imaging Protocols and Postprocessing Software Across the NCI Quantitative Imaging Network Sites Using a Digital Reference Object (DRO). (Bell LC, Semmineh N, An H, Eldeniz C, Wahl R, Schmainda KM, Prah MA, Erickson BJ, Korfiatis P, Wu C, Sorace AG, Yankeelov TE, Rutledge N, Chenevert TL, Malyarenko D, Liu Y, Brenner A, Hu LS, Zhou Y, Boxerman JL, Yen YF, Kalpathy-Cramer J, Beers AL, Muzi M, Madhuranthakam AJ, Pinho M, Johnson B, Quarles CC) Tomography 2019 Mar;5(1):110-117 PMID: 30854448 PMCID: PMC6403027 SCOPUS ID: 2-s2.0-85069176881 03/12/2019 23 Citations

The Impact of Arterial Input Function Determination Variations on Prostate Dynamic Contrast-Enhanced Magnetic Resonance Imaging Pharmacokinetic Modeling: A Multicenter Data Analysis Challenge, Part II. (Huang W, Chen Y, Fedorov A, Li X, Jajamovich GH, Malyarenko DI, Aryal MP, LaViolette PS, Oborski MJ, O'Sullivan F, Abramson RG, Jafari-Khouzani K, Afzal A, Tudorica A, Moloney B, Gupta SN, Besa C, Kalpathy-Cramer J, Mountz JM, Laymon CM, Muzi M, Kinahan PE, Schmainda K, Cao Y, Chenevert TL, Taouli B, Yankeelov TE, Fennessy F, Li X) Tomography 2019 Mar;5(1):99-109 PMID: 30854447 PMCID: PMC6403046 SCOPUS ID: 2-s2.0-85069224523 03/12/2019 15 Citations

Irradiation of pediatric glioblastoma cells promotes radioresistance and enhances glioma malignancy via genome-wide transcriptome changes. (Alhajala HS, Nguyen HS, Shabani S, Best B, Kaushal M, Al-Gizawiy MM, Erin Ahn EY, Knipstein JA, Mirza S, Schmainda KM, Chitambar CR, Doan NB) Oncotarget 2018 Sep 25;9(75):34122-34131 PMID: 30344926 PMCID: PMC6183347 SCOPUS ID: 2-s2.0-85053940800 10/23/2018 13 Citations

Irradiation of pediatric glioblastoma cells promotes radioresistance and enhances glioma malignancy via genome-wide transcriptome changes (Alhajala HS, Nguyen HS, Shabani S, Best B, Kaushal M, Al-Gizawiy MM, Ahn EYE, Knipstein JA, Mirza S, Schmainda KM, Chitambar CR, Doan NB) Oncotarget 1 September 2018;9(75):34122-34131 SCOPUS ID: 2-s2.0-85053940800 09/01/2018 13 Citations

ACRIN 6684: Multicenter, phase II assessment of tumor hypoxia in newly diagnosed glioblastoma using magnetic resonance spectroscopy. (Ratai EM, Zhang Z, Fink J, Muzi M, Hanna L, Greco E, Richards T, Kim D, Andronesi OC, Mintz A, Kostakoglu L, Prah M, Ellingson B, Schmainda K, Sorensen G, Barboriak D, Mankoff D, Gerstner ER, ACRIN 6684 trial group) PLoS One 2018;13(6):e0198548 PMID: 29902200 PMCID: PMC6002091 SCOPUS ID: 2-s2.0-85057530310 06/15/2018 20 Citations

Identification of radiation responsive genes and transcriptome profiling via complete RNA sequencing in a stable radioresistant U87 glioblastoma model. (Doan NB, Nguyen HS, Alhajala HS, Jaber B, Al-Gizawiy MM, Ahn EE, Mueller WM, Chitambar CR, Mirza SP, Schmainda KM) Oncotarget 2018 May 04;9(34):23532-23542 PMID: 29805753 PMCID: PMC5955095 SCOPUS ID: 2-s2.0-85046774803 05/29/2018 19 Citations

Multisite Concordance of DSC-MRI Analysis for Brain Tumors: Results of a National Cancer Institute Quantitative Imaging Network Collaborative Project. (Schmainda KM, Prah MA, Rand SD, Liu Y, Logan B, Muzi M, Rane SD, Da X, Yen YF, Kalpathy-Cramer J, Chenevert TL, Hoff B, Ross B, Cao Y, Aryal MP, Erickson B, Korfiatis P, Dondlinger T, Bell L, Hu L, Kinahan PE, Quarles CC) AJNR Am J Neuroradiol 2018 Jun;39(6):1008-1016 PMID: 29794239 PMCID: PMC6002911 SCOPUS ID: 2-s2.0-85048696048 05/26/2018 40 Citations

Gallium Maltolate Disrupts Tumor Iron Metabolism and Retards the Growth of Glioblastoma by Inhibiting Mitochondrial Function and Ribonucleotide Reductase. (Chitambar CR, Al-Gizawiy MM, Alhajala HS, Pechman KR, Wereley JP, Wujek R, Clark PA, Kuo JS, Antholine WE, Schmainda KM) Mol Cancer Ther 2018 Jun;17(6):1240-1250 PMID: 29592883 PMCID: PMC5984712 SCOPUS ID: 2-s2.0-85048073666 03/30/2018 40 Citations

Acid ceramidase and its inhibitors: a de novo drug target and a new class of drugs for killing glioblastoma cancer stem cells with high efficiency. (Doan NB, Alhajala H, Al-Gizawiy MM, Mueller WM, Rand SD, Connelly JM, Cochran EJ, Chitambar CR, Clark P, Kuo J, Schmainda KM, Mirza SP) Oncotarget 2017 Dec 22;8(68):112662-112674 PMID: 29348854 PMCID: PMC5762539 SCOPUS ID: 2-s2.0-85038823142 01/20/2018 55 Citations

Toward uniform implementation of parametric map Digital Imaging and Communication in Medicine standard in multisite quantitative diffusion imaging studies. (Malyarenko D, Fedorov A, Bell L, Prah M, Hectors S, Arlinghaus L, Muzi M, Solaiyappan M, Jacobs M, Fung M, Shukla-Dave A, McManus K, Boss M, Taouli B, Yankeelov TE, Quarles CC, Schmainda K, Chenevert TL, Newitt DC) J Med Imaging (Bellingham) 2018 Jan;5(1):011006 PMID: 29134189 PMCID: PMC5658654 SCOPUS ID: 2-s2.0-85033437268 11/15/2017 9 Citations

Multisite concordance of apparent diffusion coefficient measurements across the NCI Quantitative Imaging Network. (Newitt DC, Malyarenko D, Chenevert TL, Quarles CC, Bell L, Fedorov A, Fennessy F, Jacobs MA, Solaiyappan M, Hectors S, Taouli B, Muzi M, Kinahan PE, Schmainda KM, Prah MA, Taber EN, Kroenke C, Huang W, Arlinghaus LR, Yankeelov TE, Cao Y, Aryal M, Yen YF, Kalpathy-Cramer J, Shukla-Dave A, Fung M, Liang J, Boss M, Hylton N) J Med Imaging (Bellingham) 2018 Jan;5(1):011003 PMID: 29021993 PMCID: PMC5633866 SCOPUS ID: 2-s2.0-85032566078 10/13/2017 25 Citations

Spatial discrimination of glioblastoma and treatment effect with histologically-validated perfusion and diffusion magnetic resonance imaging metrics. (Prah MA, Al-Gizawiy MM, Mueller WM, Cochran EJ, Hoffmann RG, Connelly JM, Schmainda KM) J Neurooncol 2018 Jan;136(1):13-21 PMID: 28900832 PMCID: PMC5756123 SCOPUS ID: 2-s2.0-85029185195 09/14/2017 36 Citations

Acid ceramidase confers radioresistance to glioblastoma cells. (Doan NB, Nguyen HS, Al-Gizawiy MM, Mueller WM, Sabbadini RA, Rand SD, Connelly JM, Chitambar CR, Schmainda KM, Mirza SP) Oncol Rep 2017 Oct;38(4):1932-1940 PMID: 28765947 PMCID: PMC5652937 SCOPUS ID: 2-s2.0-85029804998 08/03/2017 39 Citations

Optimization of DSC MRI Echo Times for CBV Measurements Using Error Analysis in a Pilot Study of High-Grade Gliomas. (Bell LC, Does MD, Stokes AM, Baxter LC, Schmainda KM, Dueck AC, Quarles CC) AJNR Am J Neuroradiol 2017 Sep;38(9):1710-1715 PMID: 28684456 PMCID: PMC5591773 SCOPUS ID: 2-s2.0-85029232690 07/08/2017 7 Citations

Acid ceramidase is a novel drug target for pediatric brain tumors. (Doan NB, Nguyen HS, Montoure A, Al-Gizawiy MM, Mueller WM, Kurpad S, Rand SD, Connelly JM, Chitambar CR, Schmainda KM, Mirza SP) Oncotarget 2017 Apr 11;8(15):24753-24761 PMID: 28445970 PMCID: PMC5421885 SCOPUS ID: 2-s2.0-85017541087 04/28/2017 28 Citations

Spiral Perfusion Imaging With Consecutive Echoes (SPICE™) for the Simultaneous Mapping of DSC- and DCE-MRI Parameters in Brain Tumor Patients: Theory and Initial Feasibility. (Paulson ES, Prah DE, Schmainda KM) Tomography 2016 Dec;2(4):295-307 PMID: 28090589 PMCID: PMC5226659 01/17/2017

Magnetic Resonance Imaging-Based Radiomic Profiles Predict Patient Prognosis in Newly Diagnosed Glioblastoma Before Therapy. (McGarry SD, Hurrell SL, Kaczmarowski AL, Cochran EJ, Connelly J, Rand SD, Schmainda KM, LaViolette PS) Tomography 2016 Sep;2(3):223-228 PMID: 27774518 PMCID: PMC5074084 10/25/2016

Progressing Bevacizumab-Induced Diffusion Restriction Is Associated with Coagulative Necrosis Surrounded by Viable Tumor and Decreased Overall Survival in Patients with Recurrent Glioblastoma. (Nguyen HS, Milbach N, Hurrell SL, Cochran E, Connelly J, Bovi JA, Schultz CJ, Mueller WM, Rand SD, Schmainda KM, LaViolette PS) AJNR Am J Neuroradiol 2016 Dec;37(12):2201-2208 PMID: 27492073 PMCID: PMC5161572 SCOPUS ID: 2-s2.0-85006469905 08/06/2016 60 Citations

The Impact of Arterial Input Function Determination Variations on Prostate Dynamic Contrast-Enhanced Magnetic Resonance Imaging Pharmacokinetic Modeling: A Multicenter Data Analysis Challenge. (Huang W, Chen Y, Fedorov A, Li X, Jajamovich GH, Malyarenko DI, Aryal MP, LaViolette PS, Oborski MJ, O'Sullivan F, Abramson RG, Jafari-Khouzani K, Afzal A, Tudorica A, Moloney B, Gupta SN, Besa C, Kalpathy-Cramer J, Mountz JM, Laymon CM, Muzi M, Schmainda K, Cao Y, Chenevert TL, Taouli B, Yankeelov TE, Fennessy F, Li X) Tomography 2016 Mar;2(1):56-66 PMID: 27200418 PMCID: PMC4869732 05/21/2016

ACRIN 6684: Assessment of Tumor Hypoxia in Newly Diagnosed Glioblastoma Using 18F-FMISO PET and MRI. (Gerstner ER, Zhang Z, Fink JR, Muzi M, Hanna L, Greco E, Prah M, Schmainda KM, Mintz A, Kostakoglu L, Eikman EA, Ellingson BM, Ratai EM, Sorensen AG, Barboriak DP, Mankoff DA, ACRIN 6684 Trial Group) Clin Cancer Res 2016 Oct 15;22(20):5079-5086 PMID: 27185374 PMCID: PMC5065740 SCOPUS ID: 2-s2.0-84991721594 05/18/2016 97 Citations

Perfusion Imaging for Brain Tumor Characterization and Assessment of Treatment Response (Schmainda K) Handbook of Neuro-Oncology Neuroimaging: Second Edition 12 April 2016:335-351 SCOPUS ID: 2-s2.0-84978351826 04/12/2016 2 Citations

Molecular Subtypes in Glioblastoma Multiforme: Integrated Analysis Using Agilent GeneSpring and Mass Profiler Professional Multi-Omics Software (Renu D, Aggarwal P, Bhat V, Cherukuri SC, Livi C, Rosenberg M, Tata P, Al-Gizawiy M, Schmainda KM, Mizra SP) Renu D, Aggarwal P, Bhat V, Cherukuri SC, Livi C, Rosenberg M, Tata P, Al-Gizawiy M, Schmainda KM, Mirza SP. Molecular Subtypes in Glioblastoma Multiforme: Integrated Analysis using Agilent GeneSpring® Multi-Omics Software. Agilent Technologies, Inc. 2015; 5991-5505EN. 01/04/2016

Location of brain tumor intersecting white matter tracts predicts patient prognosis. (Mickevicius NJ, Carle AB, Bluemel T, Santarriaga S, Schloemer F, Shumate D, Connelly J, Schmainda KM, LaViolette PS) J Neurooncol 2015 Nov;125(2):393-400 PMID: 26376654 PMCID: PMC6094943 SCOPUS ID: 2-s2.0-84945477926 09/18/2015 26 Citations

Dynamic susceptibility contrast MRI measures of relative cerebral blood volume continue to show promise as an early response marker in the setting of bevacizumab treatment. (Boxerman JL, Schmainda KM, Zhang Z, Barboriak DP) Neuro Oncol 2015 Nov;17(11):1538-9 PMID: 26361983 PMCID: PMC4648309 SCOPUS ID: 2-s2.0-84946558454 09/13/2015 6 Citations

Repeatability of Standardized and Normalized Relative CBV in Patients with Newly Diagnosed Glioblastoma. (Prah MA, Stufflebeam SM, Paulson ES, Kalpathy-Cramer J, Gerstner ER, Batchelor TT, Barboriak DP, Rosen BR, Schmainda KM) AJNR Am J Neuroradiol 2015 Sep;36(9):1654-61 PMID: 26066626 PMCID: PMC4567906 SCOPUS ID: 2-s2.0-84941354983 06/13/2015 44 Citations

Repeatability of Cerebral Perfusion Using Dynamic Susceptibility Contrast MRI in Glioblastoma Patients. (Jafari-Khouzani K, Emblem KE, Kalpathy-Cramer J, Bjørnerud A, Vangel MG, Gerstner ER, Schmainda KM, Paynabar K, Wu O, Wen PY, Batchelor T, Rosen B, Stufflebeam SM) Transl Oncol 2015 Jun;8(3):137-46 PMID: 26055170 PMCID: PMC4486737 SCOPUS ID: 2-s2.0-84930700851 06/10/2015 36 Citations

Dynamic susceptibility contrast MRI measures of relative cerebral blood volume as a prognostic marker for overall survival in recurrent glioblastoma: results from the ACRIN 6677/RTOG 0625 multicenter trial. (Schmainda KM, Zhang Z, Prah M, Snyder BS, Gilbert MR, Sorensen AG, Barboriak DP, Boxerman JL) Neuro Oncol 2015 Aug;17(8):1148-56 PMID: 25646027 PMCID: PMC4490871 SCOPUS ID: 2-s2.0-84931849773 02/04/2015 100 Citations

Precise ex vivo histological validation of heightened cellularity and diffusion-restricted necrosis in regions of dark apparent diffusion coefficient in 7 cases of high-grade glioma. (LaViolette PS, Mickevicius NJ, Cochran EJ, Rand SD, Connelly J, Bovi JA, Malkin MG, Mueller WM, Schmainda KM) Neuro Oncol 2014 Dec;16(12):1599-606 PMID: 25059209 PMCID: PMC4232087 SCOPUS ID: 2-s2.0-84938693563 07/26/2014 64 Citations

Comprehensive characterization of glioblastoma tumor tissues for biomarker identification using mass spectrometry-based label-free quantitative proteomics. (Heroux MS, Chesnik MA, Halligan BD, Al-Gizawiy M, Connelly JM, Mueller WM, Rand SD, Cochran EJ, LaViolette PS, Malkin MG, Schmainda KM, Mirza SP) Physiol Genomics 2014 Jul 01;46(13):467-81 PMID: 24803679 PMCID: PMC4587597 SCOPUS ID: 2-s2.0-84903603535 05/08/2014 37 Citations

The effect of low b-values on the intravoxel incoherent motion derived pseudodiffusion parameter in liver. (Cohen AD, Schieke MC, Hohenwalter MD, Schmainda KM) Magn Reson Med 2015 Jan;73(1):306-11 PMID: 24478175 PMCID: PMC4317387 SCOPUS ID: 2-s2.0-84919844948 01/31/2014 95 Citations

Dynamic-susceptibility contrast agent MRI measures of relative cerebral blood volume predict response to bevacizumab in recurrent high-grade glioma. (Schmainda KM, Prah M, Connelly J, Rand SD, Hoffman RG, Mueller W, Malkin MG) Neuro Oncol 2014 Jun;16(6):880-8 PMID: 24431219 PMCID: PMC4022214 SCOPUS ID: 2-s2.0-84901024226 01/17/2014 103 Citations

Effect of contrast leakage on the detection of abnormal brain tumor vasculature in high-grade glioma. (LaViolette PS, Daun MK, Paulson ES, Schmainda KM) J Neurooncol 2014 Feb;116(3):543-549 PMID: 24293201 PMCID: PMC4316680 SCOPUS ID: 2-s2.0-84894083764 12/03/2013 8 Citations

Diffusion-weighted MRI as a biomarker for treatment response in glioma. (Schmainda KM) CNS Oncol 2012 Nov;1(2):169-80 PMID: 23936625 PMCID: PMC3734866 SCOPUS ID: 2-s2.0-84906738491 08/13/2013 46 Citations

Multiphasic modification of intrinsic functional connectivity of the rat brain during increasing levels of propofol. (Liu X, Pillay S, Li R, Vizuete JA, Pechman KR, Schmainda KM, Hudetz AG) Neuroimage 2013 Dec;83:581-92 PMID: 23851326 PMCID: PMC3815996 SCOPUS ID: 2-s2.0-84881262584 07/16/2013 50 Citations

The effect of pulse sequence parameters and contrast agent dose on percentage signal recovery in DSC-MRI: implications for clinical applications. (Boxerman JL, Paulson ES, Prah MA, Schmainda KM) AJNR Am J Neuroradiol 2013 Jul;34(7):1364-9 PMID: 23413249 PMCID: PMC4316677 SCOPUS ID: 2-s2.0-84880846810 02/16/2013 32 Citations

Effects of perfusion on diffusion changes in human brain tumors. (Cohen AD, LaViolette PS, Prah M, Connelly J, Malkin MG, Rand SD, Mueller WM, Schmainda KM) J Magn Reson Imaging 2013 Oct;38(4):868-75 PMID: 23389889 PMCID: PMC3735792 SCOPUS ID: 2-s2.0-84886901290 02/08/2013 6 Citations

Vascular change measured with independent component analysis of dynamic susceptibility contrast MRI predicts bevacizumab response in high-grade glioma. (LaViolette PS, Cohen AD, Prah MA, Rand SD, Connelly J, Malkin MG, Mueller WM, Schmainda KM) Neuro Oncol 2013 Apr;15(4):442-50 PMID: 23382287 PMCID: PMC3607265 SCOPUS ID: 2-s2.0-84875717479 02/06/2013 40 Citations

Presumed hydrogen sulfide-mediated neurotoxicity after streptococcus anginosus group meningitis. (Verma S, Landisch R, Quirk B, Schmainda K, Prah M, Whelan HT, Willoughby RE Jr) Pediatr Infect Dis J 2013 Feb;32(2):189-91 PMID: 23014355 PMCID: PMC3548939 SCOPUS ID: 2-s2.0-84873058118 09/28/2012 5 Citations

The Role of preload and leakage correction in gadolinium-based cerebral blood volume estimation determined by comparison with MION as a criterion standard. (Boxerman JL, Prah DE, Paulson ES, Machan JT, Bedekar D, Schmainda KM) AJNR Am J Neuroradiol 2012 Jun;33(6):1081-7 PMID: 22322605 PMCID: PMC4331024 SCOPUS ID: 2-s2.0-84862514014 02/11/2012 100 Citations

Evaluation of combined bevacizumab plus irinotecan therapy in brain tumors using magnetic resonance imaging measures of relative cerebral blood volume. (Pechman KR, Donohoe DL, Bedekar DP, Kurpad SN, Schmainda KM) Magn Reson Med 2012 Oct;68(4):1266-72 PMID: 22213469 PMCID: PMC3323703 SCOPUS ID: 2-s2.0-84866734674 01/04/2012 6 Citations

Graded functional diffusion map-defined characteristics of apparent diffusion coefficients predict overall survival in recurrent glioblastoma treated with bevacizumab. (Ellingson BM, Cloughesy TF, Lai A, Mischel PS, Nghiemphu PL, Lalezari S, Schmainda KM, Pope WB) Neuro Oncol 2011 Oct;13(10):1151-61 PMID: 21856685 PMCID: PMC3177656 SCOPUS ID: 2-s2.0-80755189369 08/23/2011 70 Citations

Characterization of bevacizumab dose response relationship in U87 brain tumors using magnetic resonance imaging measures of enhancing tumor volume and relative cerebral blood volume. (Pechman KR, Donohoe DL, Bedekar DP, Kurpad SN, Hoffmann RG, Schmainda KM) J Neurooncol 2011 Nov;105(2):233-9 PMID: 21533524 PMCID: PMC4323180 SCOPUS ID: 2-s2.0-82955233738 05/03/2011 17 Citations

Spatially quantifying microscopic tumor invasion and proliferation using a voxel-wise solution to a glioma growth model and serial diffusion MRI. (Ellingson BM, LaViolette PS, Rand SD, Malkin MG, Connelly JM, Mueller WM, Prost RW, Schmainda KM) Magn Reson Med 2011 Apr;65(4):1131-43 PMID: 21413079 PMCID: PMC3065939 SCOPUS ID: 2-s2.0-79952781642 03/18/2011 38 Citations

3D visualization of subdural electrode shift as measured at craniotomy reopening. (LaViolette PS, Rand SD, Ellingson BM, Raghavan M, Lew SM, Schmainda KM, Mueller W) Epilepsy Res 2011 Mar;94(1-2):102-9 PMID: 21334178 PMCID: PMC4329774 SCOPUS ID: 2-s2.0-79952455401 02/22/2011 32 Citations

Multimodality imaging of abnormal vascular perfusion and morphology in preclinical 9L gliosarcoma model. (Darpolor MM, Molthen RC, Schmainda KM) PLoS One 2011 Jan 31;6(1):e16621 PMID: 21305001 PMCID: PMC3031600 SCOPUS ID: 2-s2.0-79551648296 02/10/2011 16 Citations

Three-dimensional visualization of subdural electrodes for presurgical planning. (LaViolette PS, Rand SD, Raghavan M, Ellingson BM, Schmainda KM, Mueller W) Neurosurgery 2011 Mar;68(1 Suppl Operative):152-60; discussion 160-1 PMID: 21206319 PMCID: PMC4339031 SCOPUS ID: 2-s2.0-79951772694 01/06/2011 13 Citations

Standardization of relative cerebral blood volume (rCBV) image maps for ease of both inter- and intrapatient comparisons. (Bedekar D, Jensen T, Schmainda KM) Magn Reson Med 2010 Sep;64(3):907-13 PMID: 20806381 PMCID: PMC4323176 SCOPUS ID: 2-s2.0-77956382561 09/02/2010 62 Citations

Volumetric analysis of functional diffusion maps is a predictive imaging biomarker for cytotoxic and anti-angiogenic treatments in malignant gliomas. (Ellingson BM, Malkin MG, Rand SD, LaViolette PS, Connelly JM, Mueller WM, Schmainda KM) J Neurooncol 2011 Mar;102(1):95-103 PMID: 20798977 PMCID: PMC3033973 SCOPUS ID: 2-s2.0-79952194217 08/28/2010 56 Citations

A simple method for rectified noise floor suppression: Phase-corrected real data reconstruction with application to diffusion-weighted imaging. (Prah DE, Paulson ES, Nencka AS, Schmainda KM) Magn Reson Med 2010 Aug;64(2):418-29 PMID: 20665786 PMCID: PMC4321728 SCOPUS ID: 2-s2.0-77955111675 07/29/2010 34 Citations

Validation of functional diffusion maps (fDMs) as a biomarker for human glioma cellularity. (Ellingson BM, Malkin MG, Rand SD, Connelly JM, Quinsey C, LaViolette PS, Bedekar DP, Schmainda KM) J Magn Reson Imaging 2010 Mar;31(3):538-48 PMID: 20187195 PMCID: PMC2903058 SCOPUS ID: 2-s2.0-77649224700 02/27/2010 216 Citations

Diffusion heterogeneity tensor MRI (α-DTI): Mathematics and initial applications in spinal cord regeneration after trauma (Ellingson BM, Schmit BD, Gourab K, Sieber-Blum M, Hu YF, Schmainda KM) 46th Annual Rocky Mountain Bioengineering Symposium and 46th International ISA Biomedical Sciences Instrumentation Symposium 2009 2009;476:167-172 SCOPUS ID: 2-s2.0-72849118267 12/01/2009 4 Citations

Utility of functional diffusion maps to monitor a patient diagnosed with gliomatosis cerebri. (Ellingson BM, Rand SD, Malkin MG, Schmainda KM) J Neurooncol 2010 May;97(3):419-23 PMID: 19813078 PMCID: PMC2956408 SCOPUS ID: 2-s2.0-77953290881 10/09/2009 14 Citations

Optimized preload leakage-correction methods to improve the diagnostic accuracy of dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging in posttreatment gliomas. (Hu LS, Baxter LC, Pinnaduwage DS, Paine TL, Karis JP, Feuerstein BG, Schmainda KM, Dueck AC, Debbins J, Smith KA, Nakaji P, Eschbacher JM, Coons SW, Heiserman JE) AJNR Am J Neuroradiol 2010 Jan;31(1):40-8 PMID: 19749223 PMCID: PMC4323177 SCOPUS ID: 2-s2.0-75749125421 09/15/2009 127 Citations

Computer-aided detection of brain tumor invasion using multiparametric MRI. (Jensen TR, Schmainda KM) J Magn Reson Imaging 2009 Sep;30(3):481-9 PMID: 19711398 PMCID: PMC4321878 SCOPUS ID: 2-s2.0-69449091474 08/28/2009 34 Citations

Diffusion heterogeneity tensor MRI (α-DTI): Mathematics and initial applications in spinal cord regeneration after trauma (Ellingson BM, Schmit BD, Gourab K, Sieber-Blum M, Hu YF, Schmainda KM) Biomedical Sciences Instrumentation 2009;45:167-172 SCOPUS ID: 2-s2.0-65749111048 05/27/2009 2 Citations

Diffusion heterogeneity tensor MRI (?-Dti): mathematics and initial applications in spinal cord regeneration after trauma - biomed 2009. (Ellington BM, Schmit BD, Gourab K, Sieber-Blum M, Hu YF, Schmainda KM) Biomed Sci Instrum 2009;45:167-72 PMID: 19369758 04/17/2009

Perfusion Imaging for Brain Tumor Characterization and Assessment of Treatment Response (Provenzale JM, Schmainda K) Handbook of Neuro-Oncology Neuroimaging 2008:264-277 SCOPUS ID: 2-s2.0-78651310411 12/01/2008 10 Citations

Comparison of dynamic susceptibility-weighted contrast-enhanced MR methods: recommendations for measuring relative cerebral blood volume in brain tumors. (Paulson ES, Schmainda KM) Radiology 2008 Nov;249(2):601-13 PMID: 18780827 PMCID: PMC2657863 SCOPUS ID: 2-s2.0-56149097774 09/11/2008 276 Citations

A novel technique for modeling susceptibility-based contrast mechanisms for arbitrary microvascular geometries: the finite perturber method. (Pathak AP, Ward BD, Schmainda KM) Neuroimage 2008 Apr 15;40(3):1130-43 PMID: 18308587 PMCID: PMC2408763 SCOPUS ID: 2-s2.0-40749094526 03/01/2008 71 Citations

Assessment of the morphological and functional effects of the anti-angiogenic agent SU11657 on 9L gliosarcoma vasculature using dynamic susceptibility contrast MRI. (Quarles CC, Schmainda KM) Magn Reson Med 2007 Apr;57(4):680-7 PMID: 17390352 SCOPUS ID: 2-s2.0-34248364723 03/29/2007 40 Citations

Water diffusion heterogeneity index in the human brain is insensitive to the orientation of applied magnetic field gradients. (Bennett KM, Hyde JS, Schmainda KM) Magn Reson Med 2006 Aug;56(2):235-9 PMID: 16929466 SCOPUS ID: 2-s2.0-33746725285 08/25/2006 80 Citations

Relative cerebral blood volume maps corrected for contrast agent extravasation significantly correlate with glioma tumor grade, whereas uncorrected maps do not. (Boxerman JL, Schmainda KM, Weisskoff RM) AJNR Am J Neuroradiol 2006 Apr;27(4):859-67 PMID: 16611779 PMCID: PMC8134002 SCOPUS ID: 2-s2.0-33748084051 04/14/2006 588 Citations

Erratum: Characterization of a first-pass gradient-echo spin-echo method to predict brain tumor grade and angiogenesis (American Journal of Neuroradiology (October 2004) 25 (1524-1532)) (Schmainda KM, Rand SD, Joseph AM, Lund R, Ward BD, Pathak AP, Ulmer JL, Badruddoja MA, Krouwer HGJ) American Journal of Neuroradiology 2005;26(3):686 SCOPUS ID: 2-s2.0-30644475087 12/01/2005 1 Citation

Improving the reliability of obtaining tumor hemodynamic parameters in the presence of contrast agent extravasation. (Quarles CC, Ward BD, Schmainda KM) Magn Reson Med 2005 Jun;53(6):1307-16 PMID: 15906288 SCOPUS ID: 2-s2.0-19544371021 05/21/2005 68 Citations

Dexamethasone normalizes brain tumor hemodynamics as indicated by dynamic susceptibility contrast MRI perfusion parameters. (Quarles CC, Krouwer HG, Rand SD, Schmainda KM) Technol Cancer Res Treat 2005 Jun;4(3):245-9 PMID: 15896079 SCOPUS ID: 2-s2.0-20444367299 05/18/2005 16 Citations

SU‐FF‐J‐105: Tools for Voxel‐By‐Voxel Correlation of Radiotherapy Dose and MR Signals From Multiple Physiological/functional MRI Modalities (Ahunbay E, Schmainda K, Lund R, Prost R, Ulmer J, Alaly J, Deasy J, Schultz C, li X) Medical Physics June 2005;32(6):1944 SCOPUS ID: 2-s2.0-85024792051 01/01/2005

Intravoxel distribution of DWI decay rates reveals C6 glioma invasion in rat brain. (Bennett KM, Hyde JS, Rand SD, Bennett R, Krouwer HG, Rebro KJ, Schmainda KM) Magn Reson Med 2004 Nov;52(5):994-1004 PMID: 15508160 SCOPUS ID: 2-s2.0-7544230113 10/28/2004 56 Citations

Characterization of a first-pass gradient-echo spin-echo method to predict brain tumor grade and angiogenesis. (Schmainda KM, Rand SD, Joseph AM, Lund R, Ward BD, Pathak AP, Ulmer JL, Badruddoja MA, Krouwer HG) AJNR Am J Neuroradiol 2004 Oct;25(9):1524-32 PMID: 15502131 PMCID: PMC7976425 SCOPUS ID: 2-s2.0-16644383149 10/27/2004 180 Citations

Lesion-induced pseudo-dominance at functional magnetic resonance imaging: implications for preoperative assessments. (Ulmer JL, Hacein-Bey L, Mathews VP, Mueller WM, DeYoe EA, Prost RW, Meyer GA, Krouwer HG, Schmainda KM) Neurosurgery 2004 Sep;55(3):569-79; discussion 580-1 PMID: 15335424 SCOPUS ID: 2-s2.0-4444242673 09/01/2004 172 Citations

Antiangiogenic effects of dexamethasone in 9L gliosarcoma assessed by MRI cerebral blood volume maps. (Badruddoja MA, Krouwer HG, Rand SD, Rebro KJ, Pathak AP, Schmainda KM) Neuro Oncol 2003 Oct;5(4):235-43 PMID: 14565159 PMCID: PMC1920679 SCOPUS ID: 2-s2.0-0142061088 10/21/2003 61 Citations

Characterization of continuously distributed cortical water diffusion rates with a stretched-exponential model. (Bennett KM, Schmainda KM, Bennett RT, Rowe DB, Lu H, Hyde JS) Magn Reson Med 2003 Oct;50(4):727-34 PMID: 14523958 SCOPUS ID: 2-s2.0-0141506097 10/03/2003 406 Citations

The effect of brain tumor angiogenesis on the in vivo relationship between the gradient-echo relaxation rate change (DeltaR2*) and contrast agent (MION) dose. (Pathak AP, Rand SD, Schmainda KM) J Magn Reson Imaging 2003 Oct;18(4):397-403 PMID: 14508775 SCOPUS ID: 2-s2.0-0141730442 09/26/2003 40 Citations

Noninvasive assessment of neoplastic angiogenesis: the role of magnetic resonance imaging. (Abu-Hajir M, Rand SD, Krouwer HG, Schmainda KM) Semin Thromb Hemost 2003 Jun;29(3):309-15 PMID: 12888935 SCOPUS ID: 2-s2.0-0038095537 07/31/2003 6 Citations

Gene transfer establishes primacy of striated vs. smooth muscle sarcoglycan complex in limb-girdle muscular dystrophy. (Durbeej M, Sawatzki SM, Barresi R, Schmainda KM, Allamand V, Michele DE, Campbell KP) Proc Natl Acad Sci U S A 2003 Jul 22;100(15):8910-5 PMID: 12851463 PMCID: PMC166412 SCOPUS ID: 2-s2.0-0041806537 07/10/2003 31 Citations

Water exchange and inflow affect the accuracy of T1-GRE blood volume measurements: implications for the evaluation of tumor angiogenesis. (Kim YR, Rebro KJ, Schmainda KM) Magn Reson Med 2002 Jun;47(6):1110-20 PMID: 12111957 SCOPUS ID: 2-s2.0-0036260529 07/12/2002 56 Citations

Qualitative perfusion imaging of the human optic nerve. (Garcia GH, Donahue KM, Ulmer JL, Harris GJ) Ophthalmic Plast Reconstr Surg 2002 Mar;18(2):107-13 PMID: 11897951 SCOPUS ID: 2-s2.0-0036205183 03/19/2002 2 Citations

MR-derived cerebral blood volume maps: issues regarding histological validation and assessment of tumor angiogenesis. (Pathak AP, Schmainda KM, Ward BD, Linderman JR, Rebro KJ, Greene AS) Magn Reson Med 2001 Oct;46(4):735-47 PMID: 11590650 SCOPUS ID: 2-s2.0-0034799187 10/09/2001 112 Citations

Computed tomography vs. magnetic resonance imaging of acute bacterial sinusitis: a rabbit model. (Kerschner JE, Cruz MJ, Beste DJ, Donahue KM, Kehl KS) Am J Otolaryngol 2000;21(5):298-305 PMID: 11032293 SCOPUS ID: 2-s2.0-0033798988 10/14/2000 23 Citations

Contrast agent-enhanced magnetic resonance imaging of skeletal muscle damage in animal models of muscular dystrophy. (Straub V, Donahue KM, Allamand V, Davisson RL, Kim YR, Campbell KP) Magn Reson Med 2000 Oct;44(4):655-9 PMID: 11025524 SCOPUS ID: 2-s2.0-0033782272 10/12/2000 56 Citations

Early adenovirus-mediated gene transfer effectively prevents muscular dystrophy in alpha-sarcoglycan-deficient mice. (Allamand V, Donahue KM, Straub V, Davisson RL, Davidson BL, Campbell KP) Gene Ther 2000 Aug;7(16):1385-91 PMID: 10981665 SCOPUS ID: 2-s2.0-0033843869 09/12/2000 41 Citations

Discrimination between neoplastic and nonneoplastic brain lesions by use of proton MR spectroscopy: the limits of accuracy with a logistic regression model. (Butzen J, Prost R, Chetty V, Donahue K, Neppl R, Bowen W, Li SJ, Haughton V, Mark L, Kim T, Mueller W, Meyer G, Krouwer H, Rand S) AJNR Am J Neuroradiol 2000 Aug;21(7):1213-9 PMID: 10954271 PMCID: PMC8174924 SCOPUS ID: 2-s2.0-0033845593 08/23/2000 50 Citations

Utility of simultaneously acquired gradient-echo and spin-echo cerebral blood volume and morphology maps in brain tumor patients. (Donahue KM, Krouwer HG, Rand SD, Pathak AP, Marszalkowski CS, Censky SC, Prost RW) Magn Reson Med 2000 Jun;43(6):845-53 PMID: 10861879 SCOPUS ID: 2-s2.0-0034045183 06/22/2000 213 Citations

Simultaneous gradient-echo/spin-echo EPI of graded ischemia in human skeletal muscle. (Donahue KM, Van Kylen J, Guven S, El-Bershawi A, Luh WM, Bandettini PA, Cox RW, Hyde JS, Kissebah AH) J Magn Reson Imaging 1998;8(5):1106-13 PMID: 9786149 SCOPUS ID: 2-s2.0-0031726724 10/24/1998 55 Citations

Water diffusion and exchange as they influence contrast enhancement. (Donahue KM, Weisskoff RM, Burstein D) J Magn Reson Imaging 1997;7(1):102-10 PMID: 9039599 SCOPUS ID: 2-s2.0-0031421910 01/01/1997 233 Citations

Improving MR quantification of regional blood volume with intravascular T1 contrast agents: accuracy, precision, and water exchange. (Donahue KM, Weisskoff RM, Chesler DA, Kwong KK, Bogdanov AA Jr, Mandeville JB, Rosen BR) Magn Reson Med 1996 Dec;36(6):858-67 PMID: 8946351 SCOPUS ID: 2-s2.0-0029856912 12/01/1996 133 Citations

MR perfusion studies with T1-weighted echo planar imaging. (Kwong KK, Chesler DA, Weisskoff RM, Donahue KM, Davis TL, Ostergaard L, Campbell TA, Rosen BR) Magn Reson Med 1995 Dec;34(6):878-87 PMID: 8598815 SCOPUS ID: 2-s2.0-0028865808 12/01/1995 418 Citations

Dynamic Gd-DTPA enhanced MRI measurement of tissue cell volume fraction. (Donahue KM, Weisskoff RM, Parmelee DJ, Callahan RJ, Wilkinson RA, Mandeville JB, Rosen BR) Magn Reson Med 1995 Sep;34(3):423-32 PMID: 7500882 SCOPUS ID: 2-s2.0-0029155698 09/01/1995 90 Citations

EPI imaging of global increase of brain MR signal with breath-hold preceded by breathing O2. (Kwong KK, Wanke I, Donahue KM, Davis TL, Rosen BR) Magn Reson Med 1995 Mar;33(3):448-52 PMID: 7760716 SCOPUS ID: 2-s2.0-0028922844 03/01/1995 40 Citations

Studies of Gd-DTPA relaxivity and proton exchange rates in tissue. (Donahue KM, Burstein D, Manning WJ, Gray ML) Magn Reson Med 1994 Jul;32(1):66-76 PMID: 8084239 SCOPUS ID: 2-s2.0-0028239980 07/01/1994 308 Citations

Cadaver middle ears as models for living ears: comparisons of middle ear input immittance. (Rosowski JJ, Davis PJ, Merchant SN, Donahue KM, Coltrera MD) Ann Otol Rhinol Laryngol 1990 May;99(5 Pt 1):403-12 PMID: 2337320 SCOPUS ID: 2-s2.0-0025351787 05/01/1990 115 Citations

Spatial and temporal patterns of human jejunal contractions. (Sarna SK, Soergel KH, Harig JM, Loo FD, Wood CM, Donahue KM, Ryan RP, Arndorfer RC) Am J Physiol 1989 Sep;257(3 Pt 1):G423-32 PMID: 2782412 SCOPUS ID: 2-s2.0-0024423508 09/01/1989 67 Citations

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Profiles for MCW, MU, MSOE, UWM, BCW, CW, Froedtert, and VA Faculty

Kathleen M. Schmainda PhD

Professor

Publications (120)