Medical College of Wisconsin
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Kathleen M. Schmainda PhD

Kathleen M. Schmainda PhD

Professor

Institution: Medical College of Wisconsin
Department: Biophysics
Program: Administration

Member of the Cancer Center
Member of the Neuroscience Research Center


Publications (93)

  • Quantitative Delta T1 (dT1) as a Replacement for Adjudicated Central Reader Analysis of Contrast-Enhancing Tumor Burden: A Subanalysis of the American College of Radiology Imaging Network 6677/Radiation Therapy Oncology Group 0625 Multicenter Brain Tumor Trial. (Schmainda KM, Prah MA, Zhang Z, Snyder BS, Rand SD, Jensen TR, Barboriak DP, Boxerman JL) AJNR Am J Neuroradiol 2019 Jul;40(7):1132-1139 PMID: 31248863 PMCID: PMC6620020 SCOPUS ID: 2-s2.0-85069294543 06/30/2019    
  • Moving Toward a Consensus DSC-MRI Protocol: Validation of a Low-Flip Angle Single-Dose Option as a Reference Standard for Brain Tumors. (Schmainda KM, Prah MA, Hu LS, Quarles CC, Semmineh N, Rand SD, Connelly JM, Anderies B, Zhou Y, Liu Y, Logan B, Stokes A, Baird G, Boxerman JL) AJNR Am J Neuroradiol 2019 Apr;40(4):626-633 PMID: 30923088 PMCID: PMC6461489 SCOPUS ID: 2-s2.0-85064588009 03/30/2019       1 Citation
  • Evaluating Multisite rCBV Consistency from DSC-MRI Imaging Protocols and Postprocessing Software Across the NCI Quantitative Imaging Network Sites Using a Digital Reference Object (DRO). (Bell LC, Semmineh N, An H, Eldeniz C, Wahl R, Schmainda KM, Prah MA, Erickson BJ, Korfiatis P, Wu C, Sorace AG, Yankeelov TE, Rutledge N, Chenevert TL, Malyarenko D, Liu Y, Brenner A, Hu LS, Zhou Y, Boxerman JL, Yen YF, Kalpathy-Cramer J, Beers AL, Muzi M, Madhuranthakam AJ, Pinho M, Johnson B, Quarles CC) Tomography 2019 03;5(1):110-117 PMID: 30854448 PMCID: PMC6403027 SCOPUS ID: 2-s2.0-85069176881 03/12/2019       1 Citation
  • The Impact of Arterial Input Function Determination Variations on Prostate Dynamic Contrast-Enhanced Magnetic Resonance Imaging Pharmacokinetic Modeling: A Multicenter Data Analysis Challenge, Part II. (Huang W, Chen Y, Fedorov A, Li X, Jajamovich GH, Malyarenko DI, Aryal MP, LaViolette PS, Oborski MJ, O'Sullivan F, Abramson RG, Jafari-Khouzani K, Afzal A, Tudorica A, Moloney B, Gupta SN, Besa C, Kalpathy-Cramer J, Mountz JM, Laymon CM, Muzi M, Kinahan PE, Schmainda K, Cao Y, Chenevert TL, Taouli B, Yankeelov TE, Fennessy F, Li X) Tomography 2019 03;5(1):99-109 PMID: 30854447 PMCID: PMC6403046 SCOPUS ID: 2-s2.0-85069224523 03/12/2019    
  • Irradiation of pediatric glioblastoma cells promotes radioresistance and enhances glioma malignancy genome-wide transcriptome changes. (Alhajala HS, Nguyen HS, Shabani S, Best B, Kaushal M, Al-Gizawiy MM, Erin Ahn EY, Knipstein JA, Mirza S, Schmainda KM, Chitambar CR, Doan NB) Oncotarget 2018 Sep 25;9(75):34122-34131 PMID: 30344926 PMCID: PMC6183347 10/23/2018    
  • Irradiation of pediatric glioblastoma cells promotes radioresistance and enhances glioma malignancy via genome-wide transcriptome changes (Alhajala HS, Nguyen HS, Shabani S, Best B, Kaushal M, Al-Gizawiy MM, Ahn EYE, Knipstein JA, Mirza S, Schmainda KM, Chitambar CR, Doan NB) Oncotarget 1 September 2018;9(75):34122-34131 SCOPUS ID: 2-s2.0-85053940800 09/01/2018    
  • ACRIN 6684: Multicenter, phase II assessment of tumor hypoxia in newly diagnosed glioblastoma using magnetic resonance spectroscopy. (Ratai EM, Zhang Z, Fink J, Muzi M, Hanna L, Greco E, Richards T, Kim D, Andronesi OC, Mintz A, Kostakoglu L, Prah M, Ellingson B, Schmainda K, Sorensen G, Barboriak D, Mankoff D, Gerstner ER, ACRIN 6684 trial group) PLoS One 2018;13(6):e0198548 PMID: 29902200 PMCID: PMC6002091 SCOPUS ID: 2-s2.0-85057530310 06/15/2018       1 Citation
  • Identification of radiation responsive genes and transcriptome profiling via complete RNA sequencing in a stable radioresistant U87 glioblastoma model. (Doan NB, Nguyen HS, Alhajala HS, Jaber B, Al-Gizawiy MM, Ahn EE, Mueller WM, Chitambar CR, Mirza SP, Schmainda KM) Oncotarget 2018 May 04;9(34):23532-23542 PMID: 29805753 PMCID: PMC5955095 05/29/2018    
  • Multisite Concordance of DSC-MRI Analysis for Brain Tumors: Results of a National Cancer Institute Quantitative Imaging Network Collaborative Project. (Schmainda KM, Prah MA, Rand SD, Liu Y, Logan B, Muzi M, Rane SD, Da X, Yen YF, Kalpathy-Cramer J, Chenevert TL, Hoff B, Ross B, Cao Y, Aryal MP, Erickson B, Korfiatis P, Dondlinger T, Bell L, Hu L, Kinahan PE, Quarles CC) AJNR Am J Neuroradiol 2018 06;39(6):1008-1016 PMID: 29794239 PMCID: PMC6002911 SCOPUS ID: 2-s2.0-85048696048 05/26/2018       6 Citations
  • Gallium Maltolate Disrupts Tumor Iron Metabolism and Retards the Growth of Glioblastoma by Inhibiting Mitochondrial Function and Ribonucleotide Reductase. (Chitambar CR, Al-Gizawiy MM, Alhajala HS, Pechman KR, Wereley JP, Wujek R, Clark PA, Kuo JS, Antholine WE, Schmainda KM) Mol Cancer Ther 2018 06;17(6):1240-1250 PMID: 29592883 PMCID: PMC5984712 SCOPUS ID: 2-s2.0-85048073666 03/30/2018       6 Citations
  • Acid ceramidase and its inhibitors: a drug target and a new class of drugs for killing glioblastoma cancer stem cells with high efficiency. (Doan NB, Alhajala H, Al-Gizawiy MM, Mueller WM, Rand SD, Connelly JM, Cochran EJ, Chitambar CR, Clark P, Kuo J, Schmainda KM, Mirza SP) Oncotarget 2017 Dec 22;8(68):112662-112674 PMID: 29348854 PMCID: PMC5762539 01/20/2018    
  • Toward uniform implementation of parametric map Digital Imaging and Communication in Medicine standard in multisite quantitative diffusion imaging studies. (Malyarenko D, Fedorov A, Bell L, Prah M, Hectors S, Arlinghaus L, Muzi M, Solaiyappan M, Jacobs M, Fung M, Shukla-Dave A, McManus K, Boss M, Taouli B, Yankeelov TE, Quarles CC, Schmainda K, Chenevert TL, Newitt DC) J Med Imaging (Bellingham) 2018 Jan;5(1):011006 PMID: 29134189 PMCID: PMC5658654 11/15/2017    
  • Multisite concordance of apparent diffusion coefficient measurements across the NCI Quantitative Imaging Network. (Newitt DC, Malyarenko D, Chenevert TL, Quarles CC, Bell L, Fedorov A, Fennessy F, Jacobs MA, Solaiyappan M, Hectors S, Taouli B, Muzi M, Kinahan PE, Schmainda KM, Prah MA, Taber EN, Kroenke C, Huang W, Arlinghaus LR, Yankeelov TE, Cao Y, Aryal M, Yen YF, Kalpathy-Cramer J, Shukla-Dave A, Fung M, Liang J, Boss M, Hylton N) J Med Imaging (Bellingham) 2018 Jan;5(1):011003 PMID: 29021993 PMCID: PMC5633866 10/13/2017    
  • Spatial discrimination of glioblastoma and treatment effect with histologically-validated perfusion and diffusion magnetic resonance imaging metrics. (Prah MA, Al-Gizawiy MM, Mueller WM, Cochran EJ, Hoffmann RG, Connelly JM, Schmainda KM) J Neurooncol 2018 Jan;136(1):13-21 PMID: 28900832 PMCID: PMC5756123 SCOPUS ID: 2-s2.0-85029185195 09/14/2017       5 Citations
  • Acid ceramidase confers radioresistance to glioblastoma cells. (Doan NB, Nguyen HS, Al-Gizawiy MM, Mueller WM, Sabbadini RA, Rand SD, Connelly JM, Chitambar CR, Schmainda KM, Mirza SP) Oncol Rep 2017 Oct;38(4):1932-1940 PMID: 28765947 PMCID: PMC5652937 SCOPUS ID: 2-s2.0-85029804998 08/03/2017       10 Citations
  • Optimization of DSC MRI Echo Times for CBV Measurements Using Error Analysis in a Pilot Study of High-Grade Gliomas. (Bell LC, Does MD, Stokes AM, Baxter LC, Schmainda KM, Dueck AC, Quarles CC) AJNR Am J Neuroradiol 2017 Sep;38(9):1710-1715 PMID: 28684456 PMCID: PMC5591773 SCOPUS ID: 2-s2.0-85029232690 07/08/2017       4 Citations
  • Acid ceramidase is a novel drug target for pediatric brain tumors. (Doan NB, Nguyen HS, Montoure A, Al-Gizawiy MM, Mueller WM, Kurpad S, Rand SD, Connelly JM, Chitambar CR, Schmainda KM, Mirza SP) Oncotarget 2017 Apr 11;8(15):24753-24761 PMID: 28445970 PMCID: PMC5421885 SCOPUS ID: 2-s2.0-85017541087 04/28/2017    
  • Spiral Perfusion Imaging With Consecutive Echoes (SPICE™) for the Simultaneous Mapping of DSC- and DCE-MRI Parameters in Brain Tumor Patients: Theory and Initial Feasibility. (Paulson ES, Prah DE, Schmainda KM) Tomography 2016 Dec;2(4):295-307 PMID: 28090589 PMCID: PMC5226659 01/17/2017    
  • Magnetic Resonance Imaging-Based Radiomic Profiles Predict Patient Prognosis in Newly Diagnosed Glioblastoma Before Therapy. (McGarry SD, Hurrell SL, Kaczmarowski AL, Cochran EJ, Connelly J, Rand SD, Schmainda KM, LaViolette PS) Tomography 2016 Sep;2(3):223-228 PMID: 27774518 PMCID: PMC5074084 10/25/2016    
  • Progressing Bevacizumab-Induced Diffusion Restriction Is Associated with Coagulative Necrosis Surrounded by Viable Tumor and Decreased Overall Survival in Patients with Recurrent Glioblastoma. (Nguyen HS, Milbach N, Hurrell SL, Cochran E, Connelly J, Bovi JA, Schultz CJ, Mueller WM, Rand SD, Schmainda KM, LaViolette PS) AJNR Am J Neuroradiol 2016 Dec;37(12):2201-2208 PMID: 27492073 PMCID: PMC5161572 SCOPUS ID: 2-s2.0-85006469905 08/06/2016       17 Citations
  • The Impact of Arterial Input Function Determination Variations on Prostate Dynamic Contrast-Enhanced Magnetic Resonance Imaging Pharmacokinetic Modeling: A Multicenter Data Analysis Challenge. (Huang W, Chen Y, Fedorov A, Li X, Jajamovich GH, Malyarenko DI, Aryal MP, LaViolette PS, Oborski MJ, O'Sullivan F, Abramson RG, Jafari-Khouzani K, Afzal A, Tudorica A, Moloney B, Gupta SN, Besa C, Kalpathy-Cramer J, Mountz JM, Laymon CM, Muzi M, Schmainda K, Cao Y, Chenevert TL, Taouli B, Yankeelov TE, Fennessy F, Li X) Tomography 2016 Mar;2(1):56-66 PMID: 27200418 PMCID: PMC4869732 05/21/2016    
  • ACRIN 6684: Assessment of Tumor Hypoxia in Newly Diagnosed Glioblastoma Using 18F-FMISO PET and MRI. (Gerstner ER, Zhang Z, Fink JR, Muzi M, Hanna L, Greco E, Prah M, Schmainda KM, Mintz A, Kostakoglu L, Eikman EA, Ellingson BM, Ratai EM, Sorensen AG, Barboriak DP, Mankoff DA, ACRIN 6684 Trial Group) Clin Cancer Res 2016 Oct 15;22(20):5079-5086 PMID: 27185374 PMCID: PMC5065740 SCOPUS ID: 2-s2.0-84991721594 05/18/2016       33 Citations
  • Perfusion Imaging for Brain Tumor Characterization and Assessment of Treatment Response (Schmainda K) Handbook of Neuro-Oncology Neuroimaging: Second Edition 12 April 2016:335-351 SCOPUS ID: 2-s2.0-84978351826 04/12/2016    
  • Molecular Subtypes in Glioblastoma Multiforme: Integrated Analysis Using Agilent GeneSpring and Mass Profiler Professional Multi-Omics Software (Renu D, Aggarwal P, Bhat V, Cherukuri SC, Livi C, Rosenberg M, Tata P, Al-Gizawiy M, Schmainda KM, Mizra SP) Renu D, Aggarwal P, Bhat V, Cherukuri SC, Livi C, Rosenberg M, Tata P, Al-Gizawiy M, Schmainda KM, Mirza SP. Molecular Subtypes in Glioblastoma Multiforme: Integrated Analysis using Agilent GeneSpring® Multi-Omics Software. Agilent Technologies, Inc. 2015; 5991-5505EN. 01/04/2016    
  • Location of brain tumor intersecting white matter tracts predicts patient prognosis. (Mickevicius NJ, Carle AB, Bluemel T, Santarriaga S, Schloemer F, Shumate D, Connelly J, Schmainda KM, LaViolette PS) J Neurooncol 2015 Nov;125(2):393-400 PMID: 26376654 PMCID: PMC6094943 SCOPUS ID: 2-s2.0-84945477926 09/18/2015       6 Citations
  • Dynamic susceptibility contrast MRI measures of relative cerebral blood volume continue to show promise as an early response marker in the setting of bevacizumab treatment. (Boxerman JL, Schmainda KM, Zhang Z, Barboriak DP) Neuro Oncol 2015 Nov;17(11):1538-9 PMID: 26361983 PMCID: PMC4648309 SCOPUS ID: 2-s2.0-84946558454 09/13/2015       2 Citations
  • Repeatability of Standardized and Normalized Relative CBV in Patients with Newly Diagnosed Glioblastoma. (Prah MA, Stufflebeam SM, Paulson ES, Kalpathy-Cramer J, Gerstner ER, Batchelor TT, Barboriak DP, Rosen BR, Schmainda KM) AJNR Am J Neuroradiol 2015 Sep;36(9):1654-61 PMID: 26066626 PMCID: PMC4567906 SCOPUS ID: 2-s2.0-84941354983 06/13/2015       12 Citations
  • Repeatability of Cerebral Perfusion Using Dynamic Susceptibility Contrast MRI in Glioblastoma Patients. (Jafari-Khouzani K, Emblem KE, Kalpathy-Cramer J, Bjørnerud A, Vangel MG, Gerstner ER, Schmainda KM, Paynabar K, Wu O, Wen PY, Batchelor T, Rosen B, Stufflebeam SM) Transl Oncol 2015 Jun;8(3):137-46 PMID: 26055170 PMCID: PMC4486737 06/10/2015    
  • Dynamic susceptibility contrast MRI measures of relative cerebral blood volume as a prognostic marker for overall survival in recurrent glioblastoma: results from the ACRIN 6677/RTOG 0625 multicenter trial. (Schmainda KM, Zhang Z, Prah M, Snyder BS, Gilbert MR, Sorensen AG, Barboriak DP, Boxerman JL) Neuro Oncol 2015 Aug;17(8):1148-56 PMID: 25646027 PMCID: PMC4490871 SCOPUS ID: 2-s2.0-84931849773 02/04/2015       46 Citations
  • Precise ex vivo histological validation of heightened cellularity and diffusion-restricted necrosis in regions of dark apparent diffusion coefficient in 7 cases of high-grade glioma. (LaViolette PS, Mickevicius NJ, Cochran EJ, Rand SD, Connelly J, Bovi JA, Malkin MG, Mueller WM, Schmainda KM) Neuro Oncol 2014 Dec;16(12):1599-606 PMID: 25059209 PMCID: PMC4232087 SCOPUS ID: 2-s2.0-84938693563 07/26/2014       32 Citations
  • Comprehensive characterization of glioblastoma tumor tissues for biomarker identification using mass spectrometry-based label-free quantitative proteomics. (Heroux MS, Chesnik MA, Halligan BD, Al-Gizawiy M, Connelly JM, Mueller WM, Rand SD, Cochran EJ, LaViolette PS, Malkin MG, Schmainda KM, Mirza SP) Physiol Genomics 2014 Jul 01;46(13):467-81 PMID: 24803679 PMCID: PMC4587597 SCOPUS ID: 2-s2.0-84903603535 05/08/2014       17 Citations
  • The effect of low b-values on the intravoxel incoherent motion derived pseudodiffusion parameter in liver. (Cohen AD, Schieke MC, Hohenwalter MD, Schmainda KM) Magn Reson Med 2015 Jan;73(1):306-11 PMID: 24478175 PMCID: PMC4317387 SCOPUS ID: 2-s2.0-84919844948 01/31/2014       52 Citations
  • Dynamic-susceptibility contrast agent MRI measures of relative cerebral blood volume predict response to bevacizumab in recurrent high-grade glioma. (Schmainda KM, Prah M, Connelly J, Rand SD, Hoffman RG, Mueller W, Malkin MG) Neuro Oncol 2014 Jun;16(6):880-8 PMID: 24431219 PMCID: PMC4022214 SCOPUS ID: 2-s2.0-84901024226 01/17/2014       68 Citations
  • Effect of contrast leakage on the detection of abnormal brain tumor vasculature in high-grade glioma. (LaViolette PS, Daun MK, Paulson ES, Schmainda KM) J Neurooncol 2014 Feb;116(3):543-549 PMID: 24293201 PMCID: PMC4316680 SCOPUS ID: 2-s2.0-84894083764 12/03/2013       8 Citations
  • Diffusion-weighted MRI as a biomarker for treatment response in glioma. (Schmainda KM) CNS Oncol 2012 Nov;1(2):169-80 PMID: 23936625 PMCID: PMC3734866 SCOPUS ID: 2-s2.0-84906738491 08/13/2013       25 Citations
  • Multiphasic modification of intrinsic functional connectivity of the rat brain during increasing levels of propofol. (Liu X, Pillay S, Li R, Vizuete JA, Pechman KR, Schmainda KM, Hudetz AG) Neuroimage 2013 Dec;83:581-92 PMID: 23851326 PMCID: PMC3815996 SCOPUS ID: 2-s2.0-84881262584 07/16/2013       29 Citations
  • The effect of pulse sequence parameters and contrast agent dose on percentage signal recovery in DSC-MRI: implications for clinical applications. (Boxerman JL, Paulson ES, Prah MA, Schmainda KM) AJNR Am J Neuroradiol 2013 Jul;34(7):1364-9 PMID: 23413249 PMCID: PMC4316677 SCOPUS ID: 2-s2.0-84880846810 02/16/2013       14 Citations
  • Effects of perfusion on diffusion changes in human brain tumors. (Cohen AD, LaViolette PS, Prah M, Connelly J, Malkin MG, Rand SD, Mueller WM, Schmainda KM) J Magn Reson Imaging 2013 Oct;38(4):868-75 PMID: 23389889 PMCID: PMC3735792 SCOPUS ID: 2-s2.0-84886901290 02/08/2013       3 Citations
  • Vascular change measured with independent component analysis of dynamic susceptibility contrast MRI predicts bevacizumab response in high-grade glioma. (LaViolette PS, Cohen AD, Prah MA, Rand SD, Connelly J, Malkin MG, Mueller WM, Schmainda KM) Neuro Oncol 2013 Apr;15(4):442-50 PMID: 23382287 PMCID: PMC3607265 SCOPUS ID: 2-s2.0-84875717479 02/06/2013       36 Citations
  • Presumed hydrogen sulfide-mediated neurotoxicity after streptococcus anginosus group meningitis. (Verma S, Landisch R, Quirk B, Schmainda K, Prah M, Whelan HT, Willoughby RE Jr) Pediatr Infect Dis J 2013 Feb;32(2):189-91 PMID: 23014355 PMCID: PMC3548939 SCOPUS ID: 2-s2.0-84873058118 09/28/2012       2 Citations
  • The Role of preload and leakage correction in gadolinium-based cerebral blood volume estimation determined by comparison with MION as a criterion standard. (Boxerman JL, Prah DE, Paulson ES, Machan JT, Bedekar D, Schmainda KM) AJNR Am J Neuroradiol 2012 Jun;33(6):1081-7 PMID: 22322605 PMCID: PMC4331024 SCOPUS ID: 2-s2.0-84862514014 02/11/2012       65 Citations
  • Evaluation of combined bevacizumab plus irinotecan therapy in brain tumors using magnetic resonance imaging measures of relative cerebral blood volume. (Pechman KR, Donohoe DL, Bedekar DP, Kurpad SN, Schmainda KM) Magn Reson Med 2012 Oct;68(4):1266-72 PMID: 22213469 PMCID: PMC3323703 SCOPUS ID: 2-s2.0-84866734674 01/04/2012       5 Citations
  • Graded functional diffusion map-defined characteristics of apparent diffusion coefficients predict overall survival in recurrent glioblastoma treated with bevacizumab. (Ellingson BM, Cloughesy TF, Lai A, Mischel PS, Nghiemphu PL, Lalezari S, Schmainda KM, Pope WB) Neuro Oncol 2011 Oct;13(10):1151-61 PMID: 21856685 PMCID: PMC3177656 SCOPUS ID: 2-s2.0-80755189369 08/23/2011       55 Citations
  • Characterization of bevacizumab dose response relationship in U87 brain tumors using magnetic resonance imaging measures of enhancing tumor volume and relative cerebral blood volume. (Pechman KR, Donohoe DL, Bedekar DP, Kurpad SN, Hoffmann RG, Schmainda KM) J Neurooncol 2011 Nov;105(2):233-9 PMID: 21533524 PMCID: PMC4323180 SCOPUS ID: 2-s2.0-82955233738 05/03/2011       11 Citations
  • Spatially quantifying microscopic tumor invasion and proliferation using a voxel-wise solution to a glioma growth model and serial diffusion MRI. (Ellingson BM, LaViolette PS, Rand SD, Malkin MG, Connelly JM, Mueller WM, Prost RW, Schmainda KM) Magn Reson Med 2011 Apr;65(4):1131-43 PMID: 21413079 PMCID: PMC3065939 SCOPUS ID: 2-s2.0-79952781642 03/18/2011       35 Citations
  • 3D visualization of subdural electrode shift as measured at craniotomy reopening. (LaViolette PS, Rand SD, Ellingson BM, Raghavan M, Lew SM, Schmainda KM, Mueller W) Epilepsy Res 2011 Mar;94(1-2):102-9 PMID: 21334178 PMCID: PMC4329774 SCOPUS ID: 2-s2.0-79952455401 02/22/2011       24 Citations
  • Multimodality imaging of abnormal vascular perfusion and morphology in preclinical 9L gliosarcoma model. (Darpolor MM, Molthen RC, Schmainda KM) PLoS One 2011 Jan 31;6(1):e16621 PMID: 21305001 PMCID: PMC3031600 SCOPUS ID: 2-s2.0-79551648296 02/10/2011       13 Citations
  • Three-dimensional visualization of subdural electrodes for presurgical planning. (LaViolette PS, Rand SD, Raghavan M, Ellingson BM, Schmainda KM, Mueller W) Neurosurgery 2011 Mar;68(1 Suppl Operative):152-60; discussion 160-1 PMID: 21206319 PMCID: PMC4339031 SCOPUS ID: 2-s2.0-79951772694 01/06/2011       9 Citations
  • Standardization of relative cerebral blood volume (rCBV) image maps for ease of both inter- and intrapatient comparisons. (Bedekar D, Jensen T, Schmainda KM) Magn Reson Med 2010 Sep;64(3):907-13 PMID: 20806381 PMCID: PMC4323176 SCOPUS ID: 2-s2.0-77956382561 09/02/2010       36 Citations
  • Volumetric analysis of functional diffusion maps is a predictive imaging biomarker for cytotoxic and anti-angiogenic treatments in malignant gliomas. (Ellingson BM, Malkin MG, Rand SD, LaViolette PS, Connelly JM, Mueller WM, Schmainda KM) J Neurooncol 2011 Mar;102(1):95-103 PMID: 20798977 PMCID: PMC3033973 SCOPUS ID: 2-s2.0-79952194217 08/28/2010       51 Citations
  • A simple method for rectified noise floor suppression: Phase-corrected real data reconstruction with application to diffusion-weighted imaging. (Prah DE, Paulson ES, Nencka AS, Schmainda KM) Magn Reson Med 2010 Aug;64(2):418-29 PMID: 20665786 PMCID: PMC4321728 SCOPUS ID: 2-s2.0-77955111675 07/29/2010       15 Citations
  • Validation of functional diffusion maps (fDMs) as a biomarker for human glioma cellularity. (Ellingson BM, Malkin MG, Rand SD, Connelly JM, Quinsey C, LaViolette PS, Bedekar DP, Schmainda KM) J Magn Reson Imaging 2010 Mar;31(3):538-48 PMID: 20187195 PMCID: PMC2903058 SCOPUS ID: 2-s2.0-77649224700 02/27/2010       142 Citations
  • Diffusion heterogeneity tensor MRI (α-DTI): Mathematics and initial applications in spinal cord regeneration after trauma (Ellingson BM, Schmit BD, Gourab K, Sieber-Blum M, Hu YF, Schmainda KM) 46th Annual Rocky Mountain Bioengineering Symposium and 46th International ISA Biomedical Sciences Instrumentation Symposium 2009 2009;476:167-172 SCOPUS ID: 2-s2.0-72849118267 12/01/2009    
  • Utility of functional diffusion maps to monitor a patient diagnosed with gliomatosis cerebri. (Ellingson BM, Rand SD, Malkin MG, Schmainda KM) J Neurooncol 2010 May;97(3):419-23 PMID: 19813078 PMCID: PMC2956408 SCOPUS ID: 2-s2.0-77953290881 10/09/2009       12 Citations
  • Optimized preload leakage-correction methods to improve the diagnostic accuracy of dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging in posttreatment gliomas. (Hu LS, Baxter LC, Pinnaduwage DS, Paine TL, Karis JP, Feuerstein BG, Schmainda KM, Dueck AC, Debbins J, Smith KA, Nakaji P, Eschbacher JM, Coons SW, Heiserman JE) AJNR Am J Neuroradiol 2010 Jan;31(1):40-8 PMID: 19749223 PMCID: PMC4323177 SCOPUS ID: 2-s2.0-75749125421 09/15/2009       90 Citations
  • Computer-aided detection of brain tumor invasion using multiparametric MRI. (Jensen TR, Schmainda KM) J Magn Reson Imaging 2009 Sep;30(3):481-9 PMID: 19711398 PMCID: PMC4321878 SCOPUS ID: 2-s2.0-69449091474 08/28/2009       22 Citations
  • Diffusion heterogeneity tensor MRI (α-DTI): Mathematics and initial applications in spinal cord regeneration after trauma (Ellingson BM, Schmit BD, Gourab K, Sieber-Blum M, Hu YF, Schmainda KM) Biomedical Sciences Instrumentation 2009;45:167-172 SCOPUS ID: 2-s2.0-65749111048 05/27/2009    
  • Diffusion heterogeneity tensor MRI (?-Dti): mathematics and initial applications in spinal cord regeneration after trauma - biomed 2009. (Ellington BM, Schmit BD, Gourab K, Sieber-Blum M, Hu YF, Schmainda KM) Biomed Sci Instrum 2009;45:167-72 PMID: 19369758 04/17/2009    
  • Perfusion Imaging for Brain Tumor Characterization and Assessment of Treatment Response (Provenzale JM, Schmainda K) Handbook of Neuro-Oncology Neuroimaging 2008:264-277 SCOPUS ID: 2-s2.0-78651310411 12/01/2008    
  • Comparison of dynamic susceptibility-weighted contrast-enhanced MR methods: recommendations for measuring relative cerebral blood volume in brain tumors. (Paulson ES, Schmainda KM) Radiology 2008 Nov;249(2):601-13 PMID: 18780827 PMCID: PMC2657863 09/11/2008    
  • A novel technique for modeling susceptibility-based contrast mechanisms for arbitrary microvascular geometries: the finite perturber method. (Pathak AP, Ward BD, Schmainda KM) Neuroimage 2008 Apr 15;40(3):1130-43 PMID: 18308587 PMCID: PMC2408763 SCOPUS ID: 2-s2.0-40749094526 03/01/2008       56 Citations
  • Assessment of the morphological and functional effects of the anti-angiogenic agent SU11657 on 9L gliosarcoma vasculature using dynamic susceptibility contrast MRI. (Quarles CC, Schmainda KM) Magn Reson Med 2007 Apr;57(4):680-7 PMID: 17390352 SCOPUS ID: 2-s2.0-34248364723 03/29/2007       35 Citations
  • Water diffusion heterogeneity index in the human brain is insensitive to the orientation of applied magnetic field gradients. (Bennett KM, Hyde JS, Schmainda KM) Magn Reson Med 2006 Aug;56(2):235-9 PMID: 16929466 SCOPUS ID: 2-s2.0-33746725285 08/25/2006       58 Citations
  • Relative cerebral blood volume maps corrected for contrast agent extravasation significantly correlate with glioma tumor grade, whereas uncorrected maps do not. (Boxerman JL, Schmainda KM, Weisskoff RM) AJNR Am J Neuroradiol 2006 Apr;27(4):859-67 PMID: 16611779 SCOPUS ID: 2-s2.0-33748084051 04/14/2006       401 Citations
  • Erratum: Characterization of a first-pass gradient-echo spin-echo method to predict brain tumor grade and angiogenesis (American Journal of Neuroradiology (October 2004) 25 (1524-1532)) (Schmainda KM, Rand SD, Joseph AM, Lund R, Ward BD, Pathak AP, Ulmer JL, Badruddoja MA, Krouwer HGJ) American Journal of Neuroradiology 2005;26(3):686 SCOPUS ID: 2-s2.0-30644475087 12/01/2005    
  • Improving the reliability of obtaining tumor hemodynamic parameters in the presence of contrast agent extravasation. (Quarles CC, Ward BD, Schmainda KM) Magn Reson Med 2005 Jun;53(6):1307-16 PMID: 15906288 SCOPUS ID: 2-s2.0-19544371021 05/21/2005       56 Citations
  • Dexamethasone normalizes brain tumor hemodynamics as indicated by dynamic susceptibility contrast MRI perfusion parameters. (Quarles CC, Krouwer HG, Rand SD, Schmainda KM) Technol Cancer Res Treat 2005 Jun;4(3):245-9 PMID: 15896079 SCOPUS ID: 2-s2.0-20444367299 05/18/2005       13 Citations
  • SU‐FF‐J‐105: Tools for Voxel‐By‐Voxel Correlation of Radiotherapy Dose and MR Signals From Multiple Physiological/functional MRI Modalities (Ahunbay E, Schmainda K, Lund R, Prost R, Ulmer J, Alaly J, Deasy J, Schultz C, li X) Medical Physics June 2005;32(6):1944 SCOPUS ID: 2-s2.0-85024792051 01/01/2005    
  • Intravoxel distribution of DWI decay rates reveals C6 glioma invasion in rat brain. (Bennett KM, Hyde JS, Rand SD, Bennett R, Krouwer HG, Rebro KJ, Schmainda KM) Magn Reson Med 2004 Nov;52(5):994-1004 PMID: 15508160 SCOPUS ID: 2-s2.0-7544230113 10/28/2004       52 Citations
  • Characterization of a first-pass gradient-echo spin-echo method to predict brain tumor grade and angiogenesis. (Schmainda KM, Rand SD, Joseph AM, Lund R, Ward BD, Pathak AP, Ulmer JL, Badruddoja MA, Krouwer HG) AJNR Am J Neuroradiol 2004 Oct;25(9):1524-32 PMID: 15502131 SCOPUS ID: 2-s2.0-16644383149 10/27/2004       148 Citations
  • Lesion-induced pseudo-dominance at functional magnetic resonance imaging: implications for preoperative assessments. (Ulmer JL, Hacein-Bey L, Mathews VP, Mueller WM, DeYoe EA, Prost RW, Meyer GA, Krouwer HG, Schmainda KM) Neurosurgery 2004 Sep;55(3):569-79; discussion 580-1 PMID: 15335424 SCOPUS ID: 2-s2.0-4444242673 09/01/2004       137 Citations
  • Antiangiogenic effects of dexamethasone in 9L gliosarcoma assessed by MRI cerebral blood volume maps. (Badruddoja MA, Krouwer HG, Rand SD, Rebro KJ, Pathak AP, Schmainda KM) Neuro Oncol 2003 Oct;5(4):235-43 PMID: 14565159 PMCID: PMC1920679 SCOPUS ID: 2-s2.0-0142061088 10/21/2003       56 Citations
  • Characterization of continuously distributed cortical water diffusion rates with a stretched-exponential model. (Bennett KM, Schmainda KM, Bennett RT, Rowe DB, Lu H, Hyde JS) Magn Reson Med 2003 Oct;50(4):727-34 PMID: 14523958 SCOPUS ID: 2-s2.0-0141506097 10/03/2003       246 Citations
  • The effect of brain tumor angiogenesis on the in vivo relationship between the gradient-echo relaxation rate change (DeltaR2*) and contrast agent (MION) dose. (Pathak AP, Rand SD, Schmainda KM) J Magn Reson Imaging 2003 Oct;18(4):397-403 PMID: 14508775 SCOPUS ID: 2-s2.0-0141730442 09/26/2003       37 Citations
  • Noninvasive assessment of neoplastic angiogenesis: the role of magnetic resonance imaging. (Abu-Hajir M, Rand SD, Krouwer HG, Schmainda KM) Semin Thromb Hemost 2003 Jun;29(3):309-15 PMID: 12888935 SCOPUS ID: 2-s2.0-0038095537 07/31/2003       6 Citations
  • Gene transfer establishes primacy of striated vs. smooth muscle sarcoglycan complex in limb-girdle muscular dystrophy. (Durbeej M, Sawatzki SM, Barresi R, Schmainda KM, Allamand V, Michele DE, Campbell KP) Proc Natl Acad Sci U S A 2003 Jul 22;100(15):8910-5 PMID: 12851463 PMCID: PMC166412 SCOPUS ID: 2-s2.0-0041806537 07/10/2003       29 Citations
  • Water exchange and inflow affect the accuracy of T1-GRE blood volume measurements: implications for the evaluation of tumor angiogenesis. (Kim YR, Rebro KJ, Schmainda KM) Magn Reson Med 2002 Jun;47(6):1110-20 PMID: 12111957 SCOPUS ID: 2-s2.0-0036260529 07/12/2002       55 Citations
  • Qualitative perfusion imaging of the human optic nerve. (Garcia GH, Donahue KM, Ulmer JL, Harris GJ) Ophthalmic Plast Reconstr Surg 2002 Mar;18(2):107-13 PMID: 11897951 SCOPUS ID: 2-s2.0-0036205183 03/19/2002       2 Citations
  • MR-derived cerebral blood volume maps: issues regarding histological validation and assessment of tumor angiogenesis. (Pathak AP, Schmainda KM, Ward BD, Linderman JR, Rebro KJ, Greene AS) Magn Reson Med 2001 Oct;46(4):735-47 PMID: 11590650 SCOPUS ID: 2-s2.0-0034799187 10/09/2001       99 Citations
  • Computed tomography vs. magnetic resonance imaging of acute bacterial sinusitis: a rabbit model. (Kerschner JE, Cruz MJ, Beste DJ, Donahue KM, Kehl KS) Am J Otolaryngol 2000 Sep-Oct;21(5):298-305 PMID: 11032293 10/14/2000       15 Citations
  • Contrast agent-enhanced magnetic resonance imaging of skeletal muscle damage in animal models of muscular dystrophy. (Straub V, Donahue KM, Allamand V, Davisson RL, Kim YR, Campbell KP) Magn Reson Med 2000 Oct;44(4):655-9 PMID: 11025524 10/12/2000       52 Citations
  • Early adenovirus-mediated gene transfer effectively prevents muscular dystrophy in alpha-sarcoglycan-deficient mice. (Allamand V, Donahue KM, Straub V, Davisson RL, Davidson BL, Campbell KP) Gene Ther 2000 Aug;7(16):1385-91 PMID: 10981665 09/12/2000       36 Citations
  • Discrimination between neoplastic and nonneoplastic brain lesions by use of proton MR spectroscopy: the limits of accuracy with a logistic regression model. (Butzen J, Prost R, Chetty V, Donahue K, Neppl R, Bowen W, Li SJ, Haughton V, Mark L, Kim T, Mueller W, Meyer G, Krouwer H, Rand S) AJNR Am J Neuroradiol 2000 Aug;21(7):1213-9 PMID: 10954271 SCOPUS ID: 2-s2.0-0033845593 08/23/2000       42 Citations
  • Utility of simultaneously acquired gradient-echo and spin-echo cerebral blood volume and morphology maps in brain tumor patients. (Donahue KM, Krouwer HG, Rand SD, Pathak AP, Marszalkowski CS, Censky SC, Prost RW) Magn Reson Med 2000 Jun;43(6):845-53 PMID: 10861879 06/22/2000       182 Citations
  • Simultaneous gradient-echo/spin-echo EPI of graded ischemia in human skeletal muscle. (Donahue KM, Van Kylen J, Guven S, El-Bershawi A, Luh WM, Bandettini PA, Cox RW, Hyde JS, Kissebah AH) J Magn Reson Imaging 1998 Sep-Oct;8(5):1106-13 PMID: 9786149 10/24/1998       50 Citations
  • Water diffusion and exchange as they influence contrast enhancement. (Donahue KM, Weisskoff RM, Burstein D) J Magn Reson Imaging 1997 Jan-Feb;7(1):102-10 PMID: 9039599 01/01/1997       212 Citations
  • Improving MR quantification of regional blood volume with intravascular T1 contrast agents: accuracy, precision, and water exchange. (Donahue KM, Weisskoff RM, Chesler DA, Kwong KK, Bogdanov AA Jr, Mandeville JB, Rosen BR) Magn Reson Med 1996 Dec;36(6):858-67 PMID: 8946351 12/01/1996       127 Citations
  • MR perfusion studies with T1-weighted echo planar imaging. (Kwong KK, Chesler DA, Weisskoff RM, Donahue KM, Davis TL, Ostergaard L, Campbell TA, Rosen BR) Magn Reson Med 1995 Dec;34(6):878-87 PMID: 8598815 12/01/1995       387 Citations
  • Dynamic Gd-DTPA enhanced MRI measurement of tissue cell volume fraction. (Donahue KM, Weisskoff RM, Parmelee DJ, Callahan RJ, Wilkinson RA, Mandeville JB, Rosen BR) Magn Reson Med 1995 Sep;34(3):423-32 PMID: 7500882 09/01/1995       80 Citations
  • EPI imaging of global increase of brain MR signal with breath-hold preceded by breathing O2. (Kwong KK, Wanke I, Donahue KM, Davis TL, Rosen BR) Magn Reson Med 1995 Mar;33(3):448-52 PMID: 7760716 03/01/1995       38 Citations
  • Studies of Gd-DTPA relaxivity and proton exchange rates in tissue. (Donahue KM, Burstein D, Manning WJ, Gray ML) Magn Reson Med 1994 Jul;32(1):66-76 PMID: 8084239 07/01/1994       288 Citations
  • Cadaver middle ears as models for living ears: comparisons of middle ear input immittance. (Rosowski JJ, Davis PJ, Merchant SN, Donahue KM, Coltrera MD) Ann Otol Rhinol Laryngol 1990 May;99(5 Pt 1):403-12 PMID: 2337320 05/01/1990       96 Citations
  • Spatial and temporal patterns of human jejunal contractions. (Sarna SK, Soergel KH, Harig JM, Loo FD, Wood CM, Donahue KM, Ryan RP, Arndorfer RC) Am J Physiol 1989 Sep;257(3 Pt 1):G423-32 PMID: 2782412 09/01/1989       61 Citations
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