Medical College of Wisconsin
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Li Lily Wang PhD

Li Lily Wang PhD

Associate Professor

Institution: Medical College of Wisconsin
Department: Microbiology and Immunology

Member of the Cancer Center


  • The structure, expression, and multifaceted role of immune-checkpoint protein VISTA as a critical regulator of anti-tumor immunity, autoimmunity, and inflammation. (Xu W, Hiếu T, Malarkannan S, Wang L) Cell Mol Immunol 2018 May;15(5):438-446 PMID: 29375120 PMCID: PMC6068175 01/30/2018       3 Citations
  • Immune-checkpoint protein VISTA critically regulates the IL-23/IL-17 inflammatory axis. (Li N, Xu W, Yuan Y, Ayithan N, Imai Y, Wu X, Miller H, Olson M, Feng Y, Huang YH, Jo Turk M, Hwang ST, Malarkannan S, Wang L) Sci Rep 2017 05 03;7(1):1485 PMID: 28469254 PMCID: PMC5431161 05/05/2017       5 Citations
  • Selective Involvement of the Checkpoint Regulator VISTA in Suppression of B-Cell, but Not T-Cell, Responsiveness by Monocytic Myeloid-Derived Suppressor Cells from Mice Infected with an Immunodeficiency-Causing Retrovirus. (Green KA, Wang L, Noelle RJ, Green WR) J Virol 2015 Sep;89(18):9693-8 PMID: 26157131 PMCID: PMC4542392 07/15/2015       16 Citations
  • Cutting Edge: PD-1 Regulates Imiquimod-Induced Psoriasiform Dermatitis through Inhibition of IL-17A Expression by Innate γδ-Low T Cells. (Imai Y, Ayithan N, Wu X, Yuan Y, Wang L, Hwang ST) J Immunol 2015 Jul 15;195(2):421-5 PMID: 26048148 PMCID: PMC4490979 06/07/2015       17 Citations
  • Immune-checkpoint proteins VISTA and PD-1 nonredundantly regulate murine T-cell responses. (Liu J, Yuan Y, Chen W, Putra J, Suriawinata AA, Schenk AD, Miller HE, Guleria I, Barth RJ, Huang YH, Wang L) Proc Natl Acad Sci U S A 2015 May 26;112(21):6682-7 PMID: 25964334 PMCID: PMC4450438 05/13/2015       65 Citations
  • Disruption of the immune-checkpoint VISTA gene imparts a proinflammatory phenotype with predisposition to the development of autoimmunity. (Wang L, Le Mercier I, Putra J, Chen W, Liu J, Schenk AD, Nowak EC, Suriawinata AA, Li J, Noelle RJ) Proc Natl Acad Sci U S A 2014 Oct 14;111(41):14846-51 PMID: 25267631 PMCID: PMC4205642 10/01/2014       45 Citations
  • VISTA is a novel broad-spectrum negative checkpoint regulator for cancer immunotherapy. (Lines JL, Sempere LF, Broughton T, Wang L, Noelle R) Cancer Immunol Res 2014 Jun;2(6):510-7 PMID: 24894088 PMCID: PMC4085258 06/05/2014       57 Citations
  • VISTA is an immune checkpoint molecule for human T cells. (Lines JL, Pantazi E, Mak J, Sempere LF, Wang L, O'Connell S, Ceeraz S, Suriawinata AA, Yan S, Ernstoff MS, Noelle R) Cancer Res 2014 Apr 01;74(7):1924-32 PMID: 24691993 PMCID: PMC3979527 04/03/2014       94 Citations
  • VISTA Regulates the Development of Protective Antitumor Immunity. (Le Mercier I, Chen W, Lines JL, Day M, Li J, Sergent P, Noelle RJ, Wang L) Cancer Res 2014 Apr 01;74(7):1933-44 PMID: 24691994 PMCID: PMC4116689 04/03/2014       93 Citations
  • Regulatory T Cell Mediator Proteins and Uses Thereof (Randolph J Noelle, Li Wang) 07/31/2012    
  • VISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responses. (Wang L, Rubinstein R, Lines JL, Wasiuk A, Ahonen C, Guo Y, Lu LF, Gondek D, Wang Y, Fava RA, Fiser A, Almo S, Noelle RJ) J Exp Med 2011 Mar 14;208(3):577-92 PMID: 21383057 PMCID: PMC3058578 03/09/2011       143 Citations
  • Adaptive Treg generation by DCs and their functional analysis. (Wang L) Methods Mol Biol 2010;595:403-12 PMID: 19941127 11/27/2009       4 Citations
  • Polyethylenimine-based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity. (Cubillos-Ruiz JR, Engle X, Scarlett UK, Martinez D, Barber A, Elgueta R, Wang L, Nesbeth Y, Durant Y, Gewirtz AT, Sentman CL, Kedl R, Conejo-Garcia JR) J Clin Invest 2009 Aug;119(8):2231-44 PMID: 19620771 PMCID: PMC2719935 07/22/2009       135 Citations
  • Programmed death 1 ligand signaling regulates the generation of adaptive Foxp3+CD4+ regulatory T cells. (Wang L, Pino-Lagos K, de Vries VC, Guleria I, Sayegh MH, Noelle RJ) Proc Natl Acad Sci U S A 2008 Jul 08;105(27):9331-6 PMID: 18599457 PMCID: PMC2442817 07/05/2008       240 Citations
  • Last update: 04/21/2018
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