Medical College of Wisconsin
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Lisa Morselli MD, PhD

Lisa Morselli MD, PhD profile photo picture

Assistant Professor

Institution: Medical College of Wisconsin
Department: Medicine
Division: Endocrinology
Program: Administration

Member of the Cardiovascular Center

View Curriculum Vitae

Research Experience

  • Adult
  • Appetite Regulation
  • Arcuate Nucleus of Hypothalamus
  • Body Mass Index
  • Energy Metabolism
  • Female
  • Humans
  • Male
  • Obesity
  • Sleep
  • Sleep Deprivation

    • Publications (36)

  • Angiotensin in the Arcuate: Mechanisms Integrating Cardiometabolic Control: The 2022 COH Mid-Career Award for Research Excellence. (Lawton SBR, Wagner VA, Nakagawa P, Segar JL, Sigmund CD, Morselli LL, Grobe JL) Hypertension 2024 Nov;81(11):2209-2217 PMID: 39315447 PMCID: PMC11483214 SCOPUS ID: 2-s2.0-85205521844 09/24/2024       2 Citations
  • Long-term Metabolic Dysfunction Programming in Female Mice by Serial Moderate Restriction of a High-fat High-sucrose Diet. (Wildes MP, Fernando DG, Grobe CC, Reho JJ, Grobe JL, Kidambi S, Kindel TL, Kwitek AE, Segar JL, Williams JS, Morselli LL) Endocrinology 2024 Aug 27;165(10) PMID: 39236000 PMCID: PMC11408931 SCOPUS ID: 2-s2.0-85204510410 09/05/2024    
  • Diet in Food Insecurity: A Mediator of Metabolic Health? (Morselli LL, Amjad R, James R, Kindel TL, Kwitek AE, Williams JS, Grobe JL, Kidambi S) J Endocr Soc 2024 Apr 06;8(6):bvae062 PMID: 38623381 PMCID: PMC11017326 SCOPUS ID: 2-s2.0-85190716270 04/16/2024       1 Citation
  • Krüppel-like factor 4 in transcriptional control of the three unique isoforms of Agouti-related peptide in mice. (Ritter ML, Wagner VA, Balapattabi K, Opichka MA, Lu KT, Wackman KK, Reho JJ, Keen HL, Kwitek AE, Morselli LL, Geurts AM, Sigmund CD, Grobe JL) Physiol Genomics 2024 Mar 01;56(3):265-275 PMID: 38145289 PMCID: PMC10866620 SCOPUS ID: 2-s2.0-85185200180 12/25/2023    
  • Angiotensin AT1A receptor signal switching in Agouti-related peptide neurons mediates metabolic rate adaptation during obesity. (Balapattabi K, Yavuz Y, Jiang J, Deng G, Mathieu NM, Ritter ML, Opichka MA, Reho JJ, McCorvy JD, Nakagawa P, Morselli LL, Mouradian GC Jr, Atasoy D, Cui H, Hodges MR, Sigmund CD, Grobe JL) Cell Rep 2023 Aug 29;42(8):112935 PMID: 37540598 PMCID: PMC10530419 SCOPUS ID: 2-s2.0-85169503465 08/04/2023       5 Citations
  • Cell-specific transcriptome changes in the hypothalamic arcuate nucleus in a mouse deoxycorticosterone acetate-salt model of hypertension. (Wagner VA, Deng G, Claflin KE, Ritter ML, Cui H, Nakagawa P, Sigmund CD, Morselli LL, Grobe JL, Kwitek AE) Front Cell Neurosci 2023;17:1207350 PMID: 37293629 PMCID: PMC10244568 SCOPUS ID: 2-s2.0-85161193387 06/09/2023       3 Citations
  • Cardiometabolic Consequences of Deleting the Regulator of G protein Signaling-2 (Rgs2) From Cells Expressing Agouti-Related Peptide or the ANG (Angiotensin) II Type 1A Receptor in Mice. (Ritter ML, Deng G, Reho JJ, Deng Y, Sapouckey SA, Opichka MA, Balapattabi K, Wackman KK, Brozoski DT, Lu KT, Paradee WJ, Gibson-Corley KN, Cui H, Nakagawa P, Morselli LL, Sigmund CD, Grobe JL) Hypertension 2022 Dec;79(12):2843-2853 PMID: 36259376 PMCID: PMC9649888 SCOPUS ID: 2-s2.0-85141891708 10/20/2022       1 Citation
  • Altered ERK-mediated control of AgRP and metabolic rate during obesity. (Ritter ML, Balapattabi K, Claflin KE, Morselli LL, Sigmund CD, Grobe JL) FASEB J 2022 May;36 Suppl 1 PMID: 35554869 SCOPUS ID: 2-s2.0-85130036996 05/14/2022    
  • Melanocortin MC4R receptor is required for energy expenditure but not blood pressure effects of angiotensin II within the mouse brain. (Oliveira V, Riedl RA, Claflin KE, Mathieu NM, Ritter ML, Balapattabi K, Wackman KK, Reho JJ, Brozoski DT, Morgan DA, Cui H, Rahmouni K, Burnett CML, Nakagawa P, Sigmund CD, Morselli LL, Grobe JL) Physiol Genomics 2022 Jun 01;54(6):196-205 PMID: 35476598 PMCID: PMC9131927 SCOPUS ID: 2-s2.0-85131018208 04/28/2022       5 Citations
  • Recent Advances in Hypertension: Intersection of Metabolic and Blood Pressure Regulatory Circuits in the Central Nervous System. (Oliveira V, Kwitek AE, Sigmund CD, Morselli LL, Grobe JL) Hypertension 2021 Apr;77(4):1061-1068 PMID: 33611936 PMCID: PMC7990288 SCOPUS ID: 2-s2.0-85102906743 02/23/2021       19 Citations
  • Single-Nucleus RNA Sequencing of the Hypothalamic Arcuate Nucleus of C57BL/6J Mice After Prolonged Diet-Induced Obesity. (Deng G, Morselli LL, Wagner VA, Balapattabi K, Sapouckey SA, Knudtson KL, Rahmouni K, Cui H, Sigmund CD, Kwitek AE, Grobe JL) Hypertension 2020 Aug;76(2):589-597 PMID: 32507042 PMCID: PMC7347451 SCOPUS ID: 2-s2.0-85087901067 06/09/2020       22 Citations
  • Association of Preoperative Body Weight and Weight Loss With Risk of Death After Bariatric Surgery. (Sun Y, Liu B, Smith JK, Correia MLG, Jones DL, Zhu Z, Taiwo A, Morselli LL, Robinson K, Hart AA, Snetselaar LG, Bao W) JAMA Netw Open 2020 May 01;3(5):e204803 PMID: 32407504 PMCID: PMC7225906 SCOPUS ID: 2-s2.0-85084963863 05/15/2020       51 Citations
  • Exploration of cardiometabolic and developmental significance of angiotensinogen expression by cells expressing the leptin receptor or agouti-related peptide. (Sapouckey SA, Morselli LL, Deng G, Patil CN, Balapattabi K, Oliveira V, Claflin KE, Gomez J, Pearson NA, Potthoff MJ, Gibson-Corley KN, Sigmund CD, Grobe JL) Am J Physiol Regul Integr Comp Physiol 2020 May 01;318(5):R855-R869 PMID: 32186897 PMCID: PMC7272763 SCOPUS ID: 2-s2.0-85083546405 03/19/2020       9 Citations
  • Prolactin-Secreting Pituitary Adenomas: Epidemiology and Natural History (Morselli LL, Schlechte JA) Contemporary Endocrinology 2019:111-126 SCOPUS ID: 2-s2.0-85065828798 01/01/2019       2 Citations
  • Determinants of Slow-Wave Activity in Overweight and Obese Adults: Roles of Sex, Obstructive Sleep Apnea and Testosterone Levels. (Morselli LL, Temple KA, Leproult R, Ehrmann DA, Van Cauter E, Mokhlesi B) Front Endocrinol (Lausanne) 2018;9:377 PMID: 30050500 PMCID: PMC6052085 SCOPUS ID: 2-s2.0-85050145418 07/28/2018       14 Citations
  • Sex Differences in the Impact of Obstructive Sleep Apnea on Glucose Metabolism. (Temple KA, Leproult R, Morselli L, Ehrmann DA, Van Cauter E, Mokhlesi B) Front Endocrinol (Lausanne) 2018;9:376 PMID: 30042734 PMCID: PMC6048262 SCOPUS ID: 2-s2.0-85050165813 07/26/2018       16 Citations
  • Control of Energy Expenditure by AgRP Neurons of the Arcuate Nucleus: Neurocircuitry, Signaling Pathways, and Angiotensin. (Morselli LL, Claflin KE, Cui H, Grobe JL) Curr Hypertens Rep 2018 Mar 19;20(3):25 PMID: 29556733 PMCID: PMC5882211 SCOPUS ID: 2-s2.0-85044249515 03/21/2018       27 Citations
  • Shared Genetic Control of Brain Activity During Sleep and Insulin Secretion: A Laboratory-Based Family Study. (Morselli LL, Gamazon ER, Tasali E, Cox NJ, Van Cauter E, Davis LK) Diabetes 2018 Jan;67(1):155-164 PMID: 29084784 PMCID: PMC5741150 SCOPUS ID: 2-s2.0-85038897497 11/01/2017       1 Citation
  • Effects of Insufficient Sleep on Pituitary-Adrenocortical Response to CRH Stimulation in Healthy Men. (Guyon A, Morselli LL, Balbo ML, Tasali E, Leproult R, L'Hermite-Balériaux M, Van Cauter E, Spiegel K) Sleep 2017 Jun 01;40(6) PMID: 28444400 PMCID: PMC6075556 SCOPUS ID: 2-s2.0-85025093316 04/27/2017       25 Citations
  • Adverse effects of two nights of sleep restriction on the hypothalamic-pituitary-adrenal axis in healthy men. (Guyon A, Balbo M, Morselli LL, Tasali E, Leproult R, L'Hermite-Balériaux M, Van Cauter E, Spiegel K) J Clin Endocrinol Metab 2014 Aug;99(8):2861-8 PMID: 24823456 PMCID: PMC4121029 SCOPUS ID: 2-s2.0-84905845339 05/16/2014       90 Citations
  • Impact of GH replacement therapy on sleep in adult patients with GH deficiency of pituitary origin. (Morselli LL, Nedeltcheva A, Leproult R, Spiegel K, Martino E, Legros JJ, Weiss RE, Mockel J, Van Cauter E, Copinschi G) Eur J Endocrinol 2013 May;168(5):763-70 PMID: 23447518 PMCID: PMC3832204 SCOPUS ID: 2-s2.0-84877154594 03/01/2013       24 Citations
  • Sleep and insulin resistance in adolescents. (Morselli LL, Knutson KL, Mokhlesi B) Sleep 2012 Oct 01;35(10):1313-4 PMID: 23024425 PMCID: PMC3443753 SCOPUS ID: 2-s2.0-84867046087 10/02/2012       8 Citations
  • Sleep and metabolic function. (Morselli LL, Guyon A, Spiegel K) Pflugers Arch 2012 Jan;463(1):139-60 PMID: 22101912 PMCID: PMC3289068 SCOPUS ID: 2-s2.0-84856709555 11/22/2011       137 Citations
  • Role of sleep duration in the regulation of glucose metabolism and appetite. (Morselli L, Leproult R, Balbo M, Spiegel K) Best Pract Res Clin Endocrinol Metab 2010 Oct;24(5):687-702 PMID: 21112019 PMCID: PMC3018785 SCOPUS ID: 2-s2.0-78649525098 11/30/2010       211 Citations
  • Sleep disturbances, daytime sleepiness, and quality of life in adults with growth hormone deficiency. (Copinschi G, Nedeltcheva A, Leproult R, Morselli LL, Spiegel K, Martino E, Legros JJ, Weiss RE, Mockel J, Van Cauter E) J Clin Endocrinol Metab 2010 May;95(5):2195-202 PMID: 20332249 PMCID: PMC2869538 SCOPUS ID: 2-s2.0-77952753125 03/25/2010       36 Citations
  • Hypopituitarism (GHD) and neurodegenerative diseases. (Morselli LL, Bogazzi F, Cecconi E, Genovesi M, Martino E, Gasperi M) J Endocrinol Invest 2008 Sep;31(9 Suppl):39-43 PMID: 19020384 SCOPUS ID: 2-s2.0-60749113806 12/17/2008       1 Citation
  • Serum pituitary antibodies in normal pregnancy and in patients with postpartum thyroiditis: a nested case-control study. (Manetti L, Parkes AB, Lupi I, Di Cianni G, Bogazzi F, Albertini S, Morselli LL, Raffaelli V, Russo D, Rossi G, Gasperi M, Lazarus JH, Martino E) Eur J Endocrinol 2008 Dec;159(6):805-9 PMID: 18787047 SCOPUS ID: 2-s2.0-58149354728 09/13/2008       11 Citations
  • Primary hyperparathyroidism is associated with marked impairment of GH response to acylated ghrelin. (Cecconi E, Bogazzi F, Morselli LL, Gasperi M, Procopio M, Gramaglia E, Broglio F, Giovannetti C, Ghigo E, Martino E) Clin Endocrinol (Oxf) 2008 Aug;69(2):197-201 PMID: 18221398 SCOPUS ID: 2-s2.0-47549105972 01/29/2008       4 Citations
  • Impairment of GH secretion in amyotrophic lateral sclerosis is not affected by riluzole treatment. (Morselli LL, Bongioanni P, Genovesi M, Licitra R, Rossi B, Murri L, Bogazzi F, Cecconi E, Martino E, Gasperi M) J Endocrinol Invest 2007 Oct;30(9):767-70 PMID: 17993769 SCOPUS ID: 2-s2.0-36949017756 11/13/2007       5 Citations
  • Prevalence and functional significance of antipituitary antibodies in patients with autoimmune and non-autoimmune thyroid diseases. (Manetti L, Lupi I, Morselli LL, Albertini S, Cosottini M, Grasso L, Genovesi M, Pinna G, Mariotti S, Bogazzi F, Bartalena L, Martino E) J Clin Endocrinol Metab 2007 Jun;92(6):2176-81 PMID: 17341554 SCOPUS ID: 2-s2.0-34347237297 03/08/2007       67 Citations
  • Bone and joint alterations in acromegaly (Morselli LL, Manetti L, Cosci C, Sardella C, Bogazzi F, Faldini C, Martino E, Gasperi M) Journal of Orthopaedics and Traumatology December 2006;7(4):169-175 SCOPUS ID: 2-s2.0-33846115529 12/01/2006       6 Citations
  • Growth hormone secretion is impaired in amyotrophic lateral sclerosis. (Morselli LL, Bongioanni P, Genovesi M, Licitra R, Rossi B, Murri L, Rossi G, Martino E, Gasperi M) Clin Endocrinol (Oxf) 2006 Sep;65(3):385-8 PMID: 16918961 SCOPUS ID: 2-s2.0-33747333574 08/22/2006       34 Citations
  • Undetectable inferior petrosal sinus levels of PTH-related peptide (PTHrP) in patients with ACTH-dependent Cushing's disease. (Manetti L, Grasso L, Vignali C, Petruzzi P, Lupi I, Genovesi M, Morselli LL, Cetani F, Acerbi G, Martino E) J Endocrinol Invest 2005 Oct;28(9):819-21 PMID: 16370562 SCOPUS ID: 2-s2.0-31544468688 12/24/2005       1 Citation
  • Thyroid function differently affects serum cystatin C and creatinine concentrations. (Manetti L, Pardini E, Genovesi M, Campomori A, Grasso L, Morselli LL, Lupi I, Pellegrini G, Bartalena L, Bogazzi F, Martino E) J Endocrinol Invest 2005 Apr;28(4):346-9 PMID: 15966508 SCOPUS ID: 2-s2.0-23444447295 06/22/2005       180 Citations
  • Early effects of methylprednisolone infusion on serum cystatin C in patients with severe Graves' ophthalmopathy. (Manetti L, Genovesi M, Pardini E, Grasso L, Lupi I, Linda Morselli L, Pellegrini G, Martino E) Clin Chim Acta 2005 Jun;356(1-2):227-8 PMID: 15936323 SCOPUS ID: 2-s2.0-20344375906 06/07/2005       33 Citations
  • Serum prostate-specific antigen concentration is increased in acromegalic women. (Manetti L, Lupi I, Genovesi M, Morselli L, Grasso L, Nencetti C, Gasperi M, Bogazzi F, Bartalena L, Martino E) J Endocrinol Invest 2004;27(7):643-7 PMID: 15505987 SCOPUS ID: 2-s2.0-5444221926 10/28/2004       3 Citations
    • Last update: 01/15/2025