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Marcelo Bonini PhD

Marcelo Bonini PhD


Institution: Medical College of Wisconsin
Department: Medicine
Division: Endocrinology
Program: Research

Member of the Cancer Center
Member of the Cardiovascular Center
Member of the Genomic Sciences and Precision Medicine Center (GSPMC)

Publications (93)

  • Cancer therapy-induced cardiovascular toxicity: old/new problems and old drugs. (Beyer AM, Bonini MG, Moslehi J) Am J Physiol Heart Circ Physiol 2019 Jul 01;317(1):H164-H167 PMID: 31172808 PMCID: PMC6692734 SCOPUS ID: 2-s2.0-85069238135 06/08/2019    
  • Injury-Induced Shedding of Extracellular Vesicles Depletes Endothelial Cells of Cav-1 (Caveolin-1) and Enables TGF-β (Transforming Growth Factor-β)-Dependent Pulmonary Arterial Hypertension. (Oliveira SDS, Chen J, Castellon M, Mao M, Raj JU, Comhair S, Erzurum S, Silva CLM, Machado RF, Bonini MG, Minshall RD) Arterioscler Thromb Vasc Biol 2019 Jun;39(6):1191-1202 PMID: 30943774 SCOPUS ID: 2-s2.0-85066511992 04/05/2019    
  • Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism. (Lee J, Yesilkanal AE, Wynne JP, Frankenberger C, Liu J, Yan J, Elbaz M, Rabe DC, Rustandy FD, Tiwari P, Grossman EA, Hart PC, Kang C, Sanderson SM, Andrade J, Nomura DK, Bonini MG, Locasale JW, Rosner MR) Nature 2019 Apr;568(7751):254-258 PMID: 30842661 PMCID: PMC6698916 SCOPUS ID: 2-s2.0-85064269030 03/08/2019       6 Citations
  • Reciprocal regulation of eNOS and caveolin-1 functions in endothelial cells. (Chen Z, D S Oliveira S, Zimnicka AM, Jiang Y, Sharma T, Chen S, Lazarov O, Bonini MG, Haus JM, Minshall RD) Mol Biol Cell 2018 05 15;29(10):1190-1202 PMID: 29563255 PMCID: PMC5935069 SCOPUS ID: 2-s2.0-85047085775 03/23/2018       5 Citations
  • Switch of Mitochondrial Superoxide Dismutase into a Prooxidant Peroxidase in Manganese-Deficient Cells and Mice. (Ganini D, Santos JH, Bonini MG, Mason RP) Cell Chem Biol 2018 04 19;25(4):413-425.e6 PMID: 29398562 PMCID: PMC5910218 SCOPUS ID: 2-s2.0-85045742134 02/06/2018       4 Citations
  • Environmental Toxicant Exposures and Type 2 Diabetes Mellitus: Two Interrelated Public Health Problems on the Rise. (Bonini MG, Sargis RM) Curr Opin Toxicol 2018 Feb;7:52-59 PMID: 29392186 PMCID: PMC5788318 02/03/2018    
  • Dicarbonyl stress and glyoxalase enzyme system regulation in human skeletal muscle. (Mey JT, Blackburn BK, Miranda ER, Chaves AB, Briller J, Bonini MG, Haus JM) Am J Physiol Regul Integr Comp Physiol 2018 02 01;314(2):R181-R190 PMID: 29046313 PMCID: PMC5867671 SCOPUS ID: 2-s2.0-85043582559 10/20/2017       5 Citations
  • Nitric oxide donor [Ru(terpy)(bdq)NO] induces uncoupling and phosphorylation of endothelial nitric oxide synthase promoting oxidant production. (Potje SR, Chen Z, Oliveira SDS, Bendhack LM, da Silva RS, Bonini MG, Antoniali C, Minshall RD) Free Radic Biol Med 2017 11;112:587-596 PMID: 28899725 PMCID: PMC5647835 SCOPUS ID: 2-s2.0-85029361713 09/14/2017       4 Citations
  • Mitochondria targeting by environmental stressors: Implications for redox cellular signaling. (Blajszczak C, Bonini MG) Toxicology 2017 11 01;391:84-89 PMID: 28750850 PMCID: PMC5939563 SCOPUS ID: 2-s2.0-85028334909 07/29/2017       19 Citations
  • Manganese superoxide dismutase (SOD2): is there a center in the universe of mitochondrial redox signaling? (Zou X, Ratti BA, O'Brien JG, Lautenschlager SO, Gius DR, Bonini MG, Zhu Y) J Bioenerg Biomembr 2017 Aug;49(4):325-333 PMID: 28616679 SCOPUS ID: 2-s2.0-85020745291 06/16/2017       23 Citations
  • Allele-specific interaction between glutathione peroxidase 1 and manganese superoxide dismutase affects the levels of Bcl-2, Sirt3 and E-cadherin. (Ekoue DN, Bera S, Ansong E, Hart PC, Zaichick S, Domann FE, Bonini MG, Diamond AM) Free Radic Res 2017 Jun;51(6):582-590 PMID: 28587495 PMCID: PMC5683088 SCOPUS ID: 2-s2.0-85021841587 06/08/2017       2 Citations
  • Selected mitochondrial DNA landscapes activate the SIRT3 axis of the UPR to promote metastasis. (Kenny TC, Hart P, Ragazzi M, Sersinghe M, Chipuk J, Sagar MAK, Eliceiri KW, LaFramboise T, Grandhi S, Santos J, Riar AK, Papa L, D'Aurello M, Manfredi G, Bonini MG, Germain D) Oncogene 2017 08;36(31):4393-4404 PMID: 28368421 PMCID: PMC5542861 SCOPUS ID: 2-s2.0-85016955700 04/04/2017       19 Citations
  • Racial disparity in survival from estrogen and progesterone receptor-positive breast cancer: implications for reducing breast cancer mortality disparities. (Rauscher GH, Silva A, Pauls H, Frasor J, Bonini MG, Hoskins K) Breast Cancer Res Treat 2017 Jun;163(2):321-330 PMID: 28251385 PMCID: PMC5410404 SCOPUS ID: 2-s2.0-85014069521 03/03/2017       5 Citations
  • Inflammation-induced caveolin-1 and BMPRII depletion promotes endothelial dysfunction and TGF-β-driven pulmonary vascular remodeling. (Oliveira SDS, Castellon M, Chen J, Bonini MG, Gu X, Elliott MH, Machado RF, Minshall RD) Am J Physiol Lung Cell Mol Physiol 2017 05 01;312(5):L760-L771 PMID: 28188225 PMCID: PMC5451590 SCOPUS ID: 2-s2.0-85018389097 02/12/2017       6 Citations
  • Manganese superoxide dismutase and glutathione peroxidase-1 contribute to the rise and fall of mitochondrial reactive oxygen species which drive oncogenesis. (Ekoue DN, He C, Diamond AM, Bonini MG) Biochim Biophys Acta Bioenerg 2017 Aug;1858(8):628-632 PMID: 28087256 PMCID: PMC5689482 SCOPUS ID: 2-s2.0-85013442829 01/15/2017       11 Citations
  • Selenium levels in human breast carcinoma tissue are associated with a common polymorphism in the gene for SELENOP (Selenoprotein P). (Ekoue DN, Zaichick S, Valyi-Nagy K, Picklo M, Lacher C, Hoskins K, Warso MA, Bonini MG, Diamond AM) J Trace Elem Med Biol 2017 Jan;39:227-233 PMID: 27908419 SCOPUS ID: 2-s2.0-84996911016 12/03/2016       6 Citations
  • Association of human papillomavirus, Neisseria gonorrhoeae and Chlamydia trachomatis co-infections on the risk of high-grade squamous intraepithelial cervical lesion. (de Abreu AL, Malaguti N, Souza RP, Uchimura NS, Ferreira ÉC, Pereira MW, Carvalho MD, Pelloso SM, Bonini MG, Gimenes F, Consolaro ME) Am J Cancer Res 2016;6(6):1371-83 PMID: 27429850 PMCID: PMC4937739 07/19/2016    
  • SOD2 and the Mitochondrial UPR: Partners Regulating Cellular Phenotypic Transitions. (He C, Hart PC, Germain D, Bonini MG) Trends Biochem Sci 2016 07;41(7):568-577 PMID: 27180143 PMCID: PMC4930371 SCOPUS ID: 2-s2.0-84970028289 05/18/2016       10 Citations
  • Type 2 Diabetes Mellitus as a Risk Factor for Alzheimer's Disease in Genes, Environment and Alzheimer's Disease (Bonds, J.A., Hart, P.C., Minshall, R.D., Lazarov, O., Haus, J.M., and Bonini, M.G.) Chapter 13 pp 387-413 04/12/2016    
  • Insulin Signaling in Bupivacaine-induced Cardiac Toxicity: Sensitization during Recovery and Potentiation by Lipid Emulsion. (Fettiplace MR, Kowal K, Ripper R, Young A, Lis K, Rubinstein I, Bonini M, Minshall R, Weinberg G) Anesthesiology 2016 Feb;124(2):428-42 PMID: 26646023 PMCID: PMC4718826 SCOPUS ID: 2-s2.0-84955752355 12/10/2015       15 Citations
  • Caveolin-1 regulates cancer cell metabolism via scavenging Nrf2 and suppressing MnSOD-driven glycolysis. (Hart PC, Ratti BA, Mao M, Ansenberger-Fricano K, Shajahan-Haq AN, Tyner AL, Minshall RD, Bonini MG) Oncotarget 2016 Jan 05;7(1):308-22 PMID: 26543228 PMCID: PMC4808000 SCOPUS ID: 2-s2.0-84997344872 11/07/2015       19 Citations
  • NOS1-derived nitric oxide promotes NF-κB transcriptional activity through inhibition of suppressor of cytokine signaling-1. (Baig MS, Zaichick SV, Mao M, de Abreu AL, Bakhshi FR, Hart PC, Saqib U, Deng J, Chatterjee S, Block ML, Vogel SM, Malik AB, Consolaro ME, Christman JW, Minshall RD, Gantner BN, Bonini MG) J Exp Med 2015 Sep 21;212(10):1725-38 PMID: 26324446 PMCID: PMC4577833 SCOPUS ID: 2-s2.0-84961216724 09/02/2015       38 Citations
  • Propofol increases morbidity and mortality in a rat model of sepsis. (Schläpfer M, Piegeler T, Dull RO, Schwartz DE, Mao M, Bonini MG, Z'Graggen BR, Beck-Schimmer B, Minshall RD) Crit Care 2015 Feb 19;19:45 PMID: 25887642 PMCID: PMC4344774 SCOPUS ID: 2-s2.0-84924245361 04/19/2015       21 Citations
  • MnSOD upregulation sustains the Warburg effect via mitochondrial ROS and AMPK-dependent signalling in cancer. (Hart PC, Mao M, de Abreu AL, Ansenberger-Fricano K, Ekoue DN, Ganini D, Kajdacsy-Balla A, Diamond AM, Minshall RD, Consolaro ME, Santos JH, Bonini MG) Nat Commun 2015 Feb 05;6:6053 PMID: 25651975 PMCID: PMC4319569 SCOPUS ID: 2-s2.0-84923169953 02/06/2015       87 Citations
  • Human leukocyte antigen (HLA)-G and cervical cancer immunoediting: a candidate molecule for therapeutic intervention and prognostic biomarker? (Gimenes F, Teixeira JJ, de Abreu AL, Souza RP, Pereira MW, da Silva VR, Bôer CG, Maria-Engler SS, Bonini MG, Borelli SD, Consolaro ME) Biochim Biophys Acta 2014 Dec;1846(2):576-89 PMID: 25453366 SCOPUS ID: 2-s2.0-84908576795 12/03/2014       19 Citations
  • Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertension. (Tang H, Chen J, Fraidenburg DR, Song S, Sysol JR, Drennan AR, Offermanns S, Ye RD, Bonini MG, Minshall RD, Garcia JG, Machado RF, Makino A, Yuan JX) Am J Physiol Lung Cell Mol Physiol 2015 Jan 15;308(2):L208-20 PMID: 25416384 PMCID: PMC4338938 SCOPUS ID: 2-s2.0-84921299135 11/25/2014       30 Citations
  • Redox regulation of NF-κB p50 and M1 polarization in microglia. (Taetzsch T, Levesque S, McGraw C, Brookins S, Luqa R, Bonini MG, Mason RP, Oh U, Block ML) Glia 2015 Mar;63(3):423-40 PMID: 25331559 PMCID: PMC4322433 SCOPUS ID: 2-s2.0-84920943047 10/22/2014       37 Citations
  • Male infertility: a public health issue caused by sexually transmitted pathogens. (Gimenes F, Souza RP, Bento JC, Teixeira JJ, Maria-Engler SS, Bonini MG, Consolaro ME) Nat Rev Urol 2014 Dec;11(12):672-87 PMID: 25330794 SCOPUS ID: 2-s2.0-84927572539 10/22/2014       75 Citations
  • Nitroglycerin tolerance in caveolin-1 deficient mice. (Mao M, Varadarajan S, Fukai T, Bakhshi FR, Chernaya O, Dudley SC Jr, Minshall RD, Bonini MG) PLoS One 2014;9(8):e104101 PMID: 25158065 PMCID: PMC4144835 SCOPUS ID: 2-s2.0-84940324992 08/27/2014       9 Citations
  • Natural allelic variations in glutathione peroxidase-1 affect its subcellular localization and function. (Bera S, Weinberg F, Ekoue DN, Ansenberger-Fricano K, Mao M, Bonini MG, Diamond AM) Cancer Res 2014 Sep 15;74(18):5118-26 PMID: 25047527 PMCID: PMC4167490 SCOPUS ID: 2-s2.0-84907546630 07/23/2014       16 Citations
  • Caveolin-1 modulates cardiac gap junction homeostasis and arrhythmogenecity by regulating cSrc tyrosine kinase. (Yang KC, Rutledge CA, Mao M, Bakhshi FR, Xie A, Liu H, Bonini MG, Patel HH, Minshall RD, Dudley SC Jr) Circ Arrhythm Electrophysiol 2014 Aug;7(4):701-10 PMID: 25017399 PMCID: PMC4198950 SCOPUS ID: 2-s2.0-84907876417 07/16/2014       15 Citations
  • Nitrosation-dependent caveolin 1 phosphorylation, ubiquitination, and degradation and its association with idiopathic pulmonary arterial hypertension. (Bakhshi FR, Mao M, Shajahan AN, Piegeler T, Chen Z, Chernaya O, Sharma T, Elliott WM, Szulcek R, Bogaard HJ, Comhair S, Erzurum S, van Nieuw Amerongen GP, Bonini MG, Minshall RD) Pulm Circ 2013 Dec;3(4):816-30 PMID: 25006397 PMCID: PMC4070841 07/10/2014    
  • Sensitive simultaneous detection of seven sexually transmitted agents in semen by multiplex-PCR and of HPV by single PCR. (Gimenes F, Medina FS, Abreu AL, Irie MM, Esquiçati IB, Malagutti N, Vasconcellos VR, Discacciati MG, Bonini MG, Maria-Engler SS, Consolaro ME) PLoS One 2014;9(6):e98862 PMID: 24921247 PMCID: PMC4055596 SCOPUS ID: 2-s2.0-84903386151 06/13/2014       26 Citations
  • Caveolin-1 Regulation of Endothelial Nitric Oxide Synthase (eNOS) Function and Oxidative Stress in the Endothelium in Systems Biology of Free Radicals and Antioxidants (Bonini, M.G., Dull, R.O. and Minshall, R.D.) pp 1343-1363 05/23/2014    
  • Regulating the regulator of ROS production. (Bonini MG, Malik AB) Cell Res 2014 Aug;24(8):908-9 PMID: 24839902 PMCID: PMC4123290 SCOPUS ID: 2-s2.0-84905591141 05/21/2014       6 Citations
  • Mitochondria and arrhythmias. (Yang KC, Bonini MG, Dudley SC Jr) Free Radic Biol Med 2014 Jun;71:351-61 PMID: 24713422 PMCID: PMC4096785 SCOPUS ID: 2-s2.0-84899441965 04/10/2014       32 Citations
  • Redox control of enzymatic functions: The electronics of life's circuitry. (Bonini MG, Consolaro MEL, Hart PC, Mao M, de Abreu ALP, Master AM) IUBMB Life 2014 Mar;66(3):167-181 PMID: 24668617 03/29/2014    
  • Evidence of a common mechanism of disassembly of adherens junctions through Gα13 targeting of VE-cadherin. (Gong H, Gao X, Feng S, Siddiqui MR, Garcia A, Bonini MG, Komarova Y, Vogel SM, Mehta D, Malik AB) J Exp Med 2014 Mar 10;211(3):579-91 PMID: 24590762 PMCID: PMC3949568 SCOPUS ID: 2-s2.0-84896846354 03/05/2014       38 Citations
  • Endothelial barrier protection by local anesthetics: ropivacaine and lidocaine block tumor necrosis factor-α-induced endothelial cell Src activation. (Piegeler T, Votta-Velis EG, Bakhshi FR, Mao M, Carnegie G, Bonini MG, Schwartz DE, Borgeat A, Beck-Schimmer B, Minshall RD) Anesthesiology 2014 Jun;120(6):1414-28 PMID: 24525631 PMCID: PMC4284094 SCOPUS ID: 2-s2.0-84901620675 02/15/2014       37 Citations
  • Cooperative interaction of trp melastatin channel transient receptor potential (TRPM2) with its splice variant TRPM2 short variant is essential for endothelial cell apoptosis. (Hecquet CM, Zhang M, Mittal M, Vogel SM, Di A, Gao X, Bonini MG, Malik AB) Circ Res 2014 Jan 31;114(3):469-79 PMID: 24337049 PMCID: PMC3978731 SCOPUS ID: 2-s2.0-84894044010 12/18/2013       29 Citations
  • The multifaceted activities of AMPK in tumor progression--why the "one size fits all" definition does not fit at all? (Bonini MG, Gantner BN) IUBMB Life 2013 Nov;65(11):889-96 PMID: 24265196 SCOPUS ID: 2-s2.0-84888419827 11/23/2013       26 Citations
  • Differences in the mutation of the p53 gene in exons 6 and 7 in cervical samples from HIV- and HPV-infected women. (Souza RP, Gimenes F, de Abreu AL, Rocha-Brischiliari SC, de Carvalho MD, Ferreira EC, Bonini MG, Pelloso SM, Consolaro ME) Infect Agent Cancer 2013 Oct 07;8(1):38 PMID: 24098975 PMCID: PMC3851445 10/09/2013    
  • Simultaneous detection of seven sexually transmitted agents in human immunodeficiency virus-infected Brazilian women by multiplex polymerase chain reaction. (Souza RP, de Abreu AL, Ferreira ÉC, Rocha-Brischiliari SC, de B Carvalho MD, Pelloso SM, Bonini MG, Gimenes F, Consolaro ME) Am J Trop Med Hyg 2013 Dec;89(6):1199-202 PMID: 24080632 PMCID: PMC3854900 SCOPUS ID: 2-s2.0-84890411961 10/02/2013       16 Citations
  • Conditional deletion of FAK in mice endothelium disrupts lung vascular barrier function due to destabilization of RhoA and Rac1 activities. (Schmidt TT, Tauseef M, Yue L, Bonini MG, Gothert J, Shen TL, Guan JL, Predescu S, Sadikot R, Mehta D) Am J Physiol Lung Cell Mol Physiol 2013 Aug 15;305(4):L291-300 PMID: 23771883 PMCID: PMC3891015 SCOPUS ID: 2-s2.0-84881644076 06/19/2013       25 Citations
  • In vivo detection of free radicals using molecular MRI and immuno-spin trapping in a mouse model for amyotrophic lateral sclerosis. (Towner RA, Smith N, Saunders D, Lupu F, Silasi-Mansat R, West M, Ramirez DC, Gomez-Mejiba SE, Bonini MG, Mason RP, Ehrenshaft M, Hensley K) Free Radic Biol Med 2013 Oct;63:351-60 PMID: 23722162 06/01/2013    
  • Microglial activation decreases retention of the protease inhibitor saquinavir: implications for HIV treatment. (Dallas S, Block ML, Thompson DM, Bonini MG, Ronaldson PT, Bendayan R, Miller DS) J Neuroinflammation 2013 May 04;10:58 PMID: 23642074 PMCID: PMC3651327 SCOPUS ID: 2-s2.0-84877000862 05/07/2013       4 Citations
  • Mitochondria oxidative stress, connexin43 remodeling, and sudden arrhythmic death. (Sovari AA, Rutledge CA, Jeong EM, Dolmatova E, Arasu D, Liu H, Vahdani N, Gu L, Zandieh S, Xiao L, Bonini MG, Duffy HS, Dudley SC Jr) Circ Arrhythm Electrophysiol 2013 Jun;6(3):623-31 PMID: 23559673 PMCID: PMC3716298 SCOPUS ID: 2-s2.0-84883029046 04/06/2013       60 Citations
  • Bioluminescent detection of peroxynitrite with a boronic acid-caged luciferin. (Sieracki NA, Gantner BN, Mao M, Horner JH, Ye RD, Malik AB, Newcomb ME, Bonini MG) Free Radic Biol Med 2013 Aug;61:40-50 PMID: 23474271 PMCID: PMC3795912 SCOPUS ID: 2-s2.0-84878846249 03/12/2013       22 Citations
  • Role of Oxidative Stress in Ventricular Arrhythmias in Ventricular Arrhythmias: From Principles to Patients (Sovari, A.A., Small, O., Bonini, M.G., Kocheril, A.G., Dudley, S.C. Jr.) Chapter 5 pp 77-94 02/01/2013    
  • Two hypotheses for the oxidation of SOD1-Cu(I). (Mason RP, Ganini D, Bonini MG, Ranguelova K) Free Radic Biol Med 2012 Nov 15;53(10):1991-2 PMID: 23137624 SCOPUS ID: 2-s2.0-84868522023 11/10/2012       1 Citation
  • Glutathiolated Ras: characterization and implications for Ras activation. (Hobbs GA, Bonini MG, Gunawardena HP, Chen X, Campbell SL) Free Radic Biol Med 2013 Apr;57:221-9 PMID: 23123410 PMCID: PMC3985386 SCOPUS ID: 2-s2.0-84874653606 11/06/2012       20 Citations
  • The peroxidase activity of mitochondrial superoxide dismutase. (Ansenberger-Fricano K, Ganini D, Mao M, Chatterjee S, Dallas S, Mason RP, Stadler K, Santos JH, Bonini MG) Free Radic Biol Med 2013 Jan;54:116-24 PMID: 22982047 PMCID: PMC4155036 SCOPUS ID: 2-s2.0-84871922397 09/18/2012       31 Citations
  • Detection of Ras GTPase protein radicals through immuno-spin trapping. (Davis MF, Zhou L, Ehrenshaft M, Ranguelova K, Gunawardena HP, Chen X, Bonini MG, Mason RP, Campbell SL) Free Radic Biol Med 2012 Sep 15;53(6):1339-45 PMID: 22819983 PMCID: PMC3549333 SCOPUS ID: 2-s2.0-84865341861 07/24/2012       9 Citations
  • In vivo imaging of immuno-spin trapped radicals with molecular magnetic resonance imaging in a diabetic mouse model. (Towner RA, Smith N, Saunders D, Henderson M, Downum K, Lupu F, Silasi-Mansat R, Ramirez DC, Gomez-Mejiba SE, Bonini MG, Ehrenshaft M, Mason RP) Diabetes 2012 Oct;61(10):2405-13 PMID: 22698922 PMCID: PMC3447912 SCOPUS ID: 2-s2.0-84866603867 06/16/2012       24 Citations
  • Kinetics of the oxidation of reduced Cu,Zn-superoxide dismutase by peroxymonocarbonate. (Ranguelova K, Ganini D, Bonini MG, London RE, Mason RP) Free Radic Biol Med 2012 Aug 01;53(3):589-94 PMID: 22569304 PMCID: PMC3408790 SCOPUS ID: 2-s2.0-84863516911 05/10/2012       15 Citations
  • Nitric oxide-dependent Src activation and resultant caveolin-1 phosphorylation promote eNOS/caveolin-1 binding and eNOS inhibition. (Chen Z, Bakhshi FR, Shajahan AN, Sharma T, Mao M, Trane A, Bernatchez P, van Nieuw Amerongen GP, Bonini MG, Skidgel RA, Malik AB, Minshall RD) Mol Biol Cell 2012 Apr;23(7):1388-98 PMID: 22323292 PMCID: PMC3315804 SCOPUS ID: 2-s2.0-84859398833 02/11/2012       61 Citations
  • Thiazolidinedione treatment decreases oxidative stress in spontaneously hypertensive heart failure rats through attenuation of inducible nitric oxide synthase-mediated lipid radical formation. (Kadiiska MB, Bonini MG, Ruggiero C, Cleland E, Wicks S, Stadler K) Diabetes 2012 Mar;61(3):586-96 PMID: 22315311 PMCID: PMC3282814 SCOPUS ID: 2-s2.0-84857382044 02/09/2012       7 Citations
  • Inhibition of c-Src tyrosine kinase prevents angiotensin II-mediated connexin-43 remodeling and sudden cardiac death. (Sovari AA, Iravanian S, Dolmatova E, Jiao Z, Liu H, Zandieh S, Kumar V, Wang K, Bernstein KE, Bonini MG, Duffy HS, Dudley SC) J Am Coll Cardiol 2011 Nov 22;58(22):2332-9 PMID: 22093512 PMCID: PMC3226807 SCOPUS ID: 2-s2.0-81255163198 11/19/2011       50 Citations
  • Nitroglycerin drives endothelial nitric oxide synthase activation via the phosphatidylinositol 3-kinase/protein kinase B pathway. (Mao M, Sudhahar V, Ansenberger-Fricano K, Fernandes DC, Tanaka LY, Fukai T, Laurindo FR, Mason RP, Vasquez-Vivar J, Minshall RD, Stadler K, Bonini MG) Free Radic Biol Med 2012 Jan 15;52(2):427-35 PMID: 22037515 PMCID: PMC3432314 SCOPUS ID: 2-s2.0-84855460214 11/01/2011       18 Citations
  • Nitric oxide suppresses tumor cell migration through N-Myc downstream-regulated gene-1 (NDRG1) expression: role of chelatable iron. (Hickok JR, Sahni S, Mikhed Y, Bonini MG, Thomas DD) J Biol Chem 2011 Dec 02;286(48):41413-24 PMID: 21976667 PMCID: PMC3308853 SCOPUS ID: 2-s2.0-82355171937 10/07/2011       51 Citations
  • Human telomerase acts as a hTR-independent reverse transcriptase in mitochondria. (Sharma NK, Reyes A, Green P, Caron MJ, Bonini MG, Gordon DM, Holt IJ, Santos JH) Nucleic Acids Res 2012 Jan;40(2):712-25 PMID: 21937513 PMCID: PMC3258147 SCOPUS ID: 2-s2.0-84855905939 09/23/2011       78 Citations
  • Effective antioxidant therapy for the management of arrhythmia. (Sovari AA, Bonini MG, Dudley SC) Expert Rev Cardiovasc Ther 2011 Jul;9(7):797-800 PMID: 21809958 PMCID: PMC4208691 SCOPUS ID: 2-s2.0-79961196063 08/04/2011       5 Citations
  • NOS-1-derived NO is an essential triggering signal for the development of systemic inflammatory responses. (Duma D, Fernandes D, Bonini MG, Stadler K, Mason RP, Assreuy J) Eur J Pharmacol 2011 Oct 01;668(1-2):285-92 PMID: 21651902 SCOPUS ID: 2-s2.0-80052066106 06/10/2011       16 Citations
  • Caveolin-1-eNOS signaling promotes p190RhoGAP-A nitration and endothelial permeability. (Siddiqui MR, Komarova YA, Vogel SM, Gao X, Bonini MG, Rajasingh J, Zhao YY, Brovkovych V, Malik AB) J Cell Biol 2011 May 30;193(5):841-50 PMID: 21624953 PMCID: PMC3105546 SCOPUS ID: 2-s2.0-79959425204 06/01/2011       65 Citations
  • Interaction of a specific population of human embryonic stem cell-derived progenitor cells with CD11b+ cells ameliorates sepsis-induced lung inflammatory injury. (Toya SP, Li F, Bonini MG, Gomez I, Mao M, Bachmaier KW, Malik AB) Am J Pathol 2011 Jan;178(1):313-24 PMID: 21224068 PMCID: PMC3069906 01/13/2011    
  • Oxidative stress induces protein and DNA radical formation in follicular dendritic cells of the germinal center and modulates its cell death patterns in late sepsis. (Chatterjee S, Lardinois O, Bhattacharjee S, Tucker J, Corbett J, Deterding L, Ehrenshaft M, Bonini MG, Mason RP) Free Radic Biol Med 2011 Apr 15;50(8):988-99 PMID: 21215311 PMCID: PMC3051032 SCOPUS ID: 2-s2.0-79952450820 01/11/2011       24 Citations
  • Partial colocalization of oxidized, N-formylkynurenine-containing proteins in mitochondria and Golgi of keratinocytes. (Ehrenshaft M, Bonini MG, Feng L, Chignell CF, Mason RP) Photochem Photobiol 2010 Jul-Aug;86(4):752-6 PMID: 20408979 PMCID: PMC3615536 SCOPUS ID: 2-s2.0-77954388280 04/23/2010       5 Citations
  • (Bi)sulfite oxidation by copper, zinc-superoxide dismutase: Sulfite-derived, radical-initiated protein radical formation. (Ranguelova K, Bonini MG, Mason RP) Environ Health Perspect 2010 Jul;118(7):970-5 PMID: 20348042 PMCID: PMC2920917 SCOPUS ID: 2-s2.0-77954837167 03/30/2010       28 Citations
  • A mutant telomerase defective in nuclear-cytoplasmic shuttling fails to immortalize cells and is associated with mitochondrial dysfunction. (Kovalenko OA, Caron MJ, Ulema P, Medrano C, Thomas AP, Kimura M, Bonini MG, Herbig U, Santos JH) Aging Cell 2010 Apr;9(2):203-19 PMID: 20089117 SCOPUS ID: 2-s2.0-77953256244 01/22/2010       54 Citations
  • Site-specific carboxypeptidase B1 tyrosine nitration and pathophysiological implications following its physical association with nitric oxide synthase-3 in experimental sepsis. (Chatterjee S, Lardinois O, Bonini MG, Bhattacharjee S, Stadler K, Corbett J, Deterding LJ, Tomer KB, Kadiiska M, Mason RP) J Immunol 2009 Sep 15;183(6):4055-66 PMID: 19717511 PMCID: PMC2804978 SCOPUS ID: 2-s2.0-70349334296 09/01/2009       25 Citations
  • Direct magnetic resonance evidence for peroxymonocarbonate involvement in the cu,zn-superoxide dismutase peroxidase catalytic cycle. (Bonini MG, Gabel SA, Ranguelova K, Stadler K, Derose EF, London RE, Mason RP) J Biol Chem 2009 May 22;284(21):14618-27 PMID: 19286663 PMCID: PMC2682909 SCOPUS ID: 2-s2.0-67649807405 03/17/2009       22 Citations
  • Immuno-spin trapping of a post-translational carboxypeptidase B1 radical formed by a dual role of xanthine oxidase and endothelial nitric oxide synthase in acute septic mice. (Chatterjee S, Ehrenshaft M, Bhattacharjee S, Deterding LJ, Bonini MG, Corbett J, Kadiiska MB, Tomer KB, Mason RP) Free Radic Biol Med 2009 Feb 15;46(4):454-61 PMID: 19049863 PMCID: PMC2661569 SCOPUS ID: 2-s2.0-58649090242 12/04/2008       27 Citations
  • Involvement of inducible nitric oxide synthase in hydroxyl radical-mediated lipid peroxidation in streptozotocin-induced diabetes. (Stadler K, Bonini MG, Dallas S, Jiang J, Radi R, Mason RP, Kadiiska MB) Free Radic Biol Med 2008 Sep 15;45(6):866-74 PMID: 18620046 PMCID: PMC2613788 SCOPUS ID: 2-s2.0-54949144344 07/16/2008       67 Citations
  • Constitutive nitric oxide synthase activation is a significant route for nitroglycerin-mediated vasodilation. (Bonini MG, Stadler K, Silva SO, Corbett J, Dore M, Petranka J, Fernandes DC, Tanaka LY, Duma D, Laurindo FR, Mason RP) Proc Natl Acad Sci U S A 2008 Jun 24;105(25):8569-74 PMID: 18562300 PMCID: PMC2438390 SCOPUS ID: 2-s2.0-47249141931 06/20/2008       23 Citations
  • Direct evidence of iNOS-mediated in vivo free radical production and protein oxidation in acetone-induced ketosis. (Stadler K, Bonini MG, Dallas S, Duma D, Mason RP, Kadiiska MB) Am J Physiol Endocrinol Metab 2008 Aug;295(2):E456-62 PMID: 18559982 PMCID: PMC2519762 SCOPUS ID: 2-s2.0-52649154098 06/19/2008       30 Citations
  • Procainamide, but not N-acetylprocainamide, induces protein free radical formation on myeloperoxidase: a potential mechanism of agranulocytosis. (Siraki AG, Deterding LJ, Bonini MG, Jiang J, Ehrenshaft M, Tomer KB, Mason RP) Chem Res Toxicol 2008 May;21(5):1143-53 PMID: 18489081 PMCID: PMC2766841 SCOPUS ID: 2-s2.0-47549089691 05/21/2008       17 Citations
  • Spatial distribution of protein damage by singlet oxygen in keratinocytes. (He YY, Council SE, Feng L, Bonini MG, Chignell CF) Photochem Photobiol 2008 Jan-Feb;84(1):69-74 PMID: 18173704 PMCID: PMC2365760 SCOPUS ID: 2-s2.0-37249087262 01/05/2008       19 Citations
  • Electron transfer between a tyrosyl radical and a cysteine residue in hemoproteins: spin trapping analysis. (Bhattacharjee S, Deterding LJ, Jiang J, Bonini MG, Tomer KB, Ramirez DC, Mason RP) J Am Chem Soc 2007 Nov 07;129(44):13493-501 PMID: 17939657 SCOPUS ID: 2-s2.0-35948939039 10/18/2007       53 Citations
  • Aminoglutethimide-induced protein free radical formation on myeloperoxidase: a potential mechanism of agranulocytosis. (Siraki AG, Bonini MG, Jiang J, Ehrenshaft M, Mason RP) Chem Res Toxicol 2007 Jul;20(7):1038-45 PMID: 17602675 PMCID: PMC2073000 SCOPUS ID: 2-s2.0-34547621062 07/03/2007       28 Citations
  • Nitric oxide cell signaling: S-nitrosation of Ras superfamily GTPases. (Raines KW, Bonini MG, Campbell SL) Cardiovasc Res 2007 Jul 15;75(2):229-39 PMID: 17559822 SCOPUS ID: 2-s2.0-34250778409 06/15/2007       44 Citations
  • Glutathione-induced radical formation on lactoperoxidase does not correlate with the enzyme's peroxidase activity. (Bonini MG, Siraki AG, Bhattacharjee S, Mason RP) Free Radic Biol Med 2007 Apr 01;42(7):985-92 PMID: 17349926 PMCID: PMC1994934 SCOPUS ID: 2-s2.0-33847747814 03/14/2007       12 Citations
  • Immunolocalization of hypochlorite-induced, catalase-bound free radical formation in mouse hepatocytes. (Bonini MG, Siraki AG, Atanassov BS, Mason RP) Free Radic Biol Med 2007 Feb 15;42(4):530-40 PMID: 17275685 PMCID: PMC1952183 SCOPUS ID: 2-s2.0-33846525435 02/06/2007       44 Citations
  • The oxidation of 2',7'-dichlorofluorescin to reactive oxygen species: a self-fulfilling prophesy? (Bonini MG, Rota C, Tomasi A, Mason RP) Free Radic Biol Med 2006 Mar 15;40(6):968-75 PMID: 16540392 SCOPUS ID: 2-s2.0-33644872102 03/17/2006       170 Citations
  • Nitrated lipids decompose to nitric oxide and lipid radicals and cause vasorelaxation. (Lima ES, Bonini MG, Augusto O, Barbeiro HV, Souza HP, Abdalla DS) Free Radic Biol Med 2005 Aug 15;39(4):532-9 PMID: 16043024 SCOPUS ID: 2-s2.0-22544469715 07/27/2005       102 Citations
  • Production of the carbonate radical anion during xanthine oxidase turnover in the presence of bicarbonate. (Bonini MG, Miyamoto S, Di Mascio P, Augusto O) J Biol Chem 2004 Dec 10;279(50):51836-43 PMID: 15448145 SCOPUS ID: 2-s2.0-10644245807 09/28/2004       57 Citations
  • Spin trapping of glutathiyl and protein radicals produced from nitric oxide-derived oxidants. (Augusto O, Bonini MG, Trindade D) Free Radic Biol Med 2004 May 15;36(10):1224-32 PMID: 15110387 SCOPUS ID: 2-s2.0-1942520352 04/28/2004       13 Citations
  • Albumin oxidation to diverse radicals by the peroxidase activity of Cu,Zn-superoxide dismutase in the presence of bicarbonate or nitrite: diffusible radicals produce cysteinyl and solvent-exposed and -unexposed tyrosyl radicals. (Bonini MG, Fernandes DC, Augusto O) Biochemistry 2004 Jan 20;43(2):344-51 PMID: 14717588 SCOPUS ID: 2-s2.0-0347724053 01/14/2004       58 Citations
  • Nitrogen dioxide and carbonate radical anion: two emerging radicals in biology. (Augusto O, Bonini MG, Amanso AM, Linares E, Santos CC, De Menezes SL) Free Radic Biol Med 2002 May 01;32(9):841-59 PMID: 11978486 SCOPUS ID: 2-s2.0-0036569412 04/30/2002       407 Citations
  • The Mechanism by which 4-hydroxy-2,2,6,6-tetramethylpiperidene-1-oxyl (tempol) diverts peroxynitrite decomposition from nitrating to nitrosating species. (Bonini MG, Mason RP, Augusto O) Chem Res Toxicol 2002 Apr;15(4):506-11 PMID: 11952336 SCOPUS ID: 2-s2.0-0036223560 04/16/2002       51 Citations
  • Carbon dioxide stimulates the production of thiyl, sulfinyl, and disulfide radical anion from thiol oxidation by peroxynitrite. (Bonini MG, Augusto O) J Biol Chem 2001 Mar 30;276(13):9749-54 PMID: 11134018 SCOPUS ID: 2-s2.0-0035971225 01/13/2001       148 Citations
  • Peroxynitrite does not decompose to singlet oxygen ((1)Delta (g)O(2)) andnitroxyl (NO(-)). (Martinez GR, Di Mascio P, Bonini MG, Augusto O, Briviba K, Sies H, Maurer P, Röthlisberger U, Herold S, Koppenol WH) Proc Natl Acad Sci U S A 2000 Sep 12;97(19):10307-12 PMID: 10973492 PMCID: PMC27019 SCOPUS ID: 2-s2.0-0034641722 09/06/2000       89 Citations
  • Role of the carbonate radical anion in tyrosine nitration and hydroxylation by peroxynitrite. (Santos CX, Bonini MG, Augusto O) Arch Biochem Biophys 2000 May 01;377(1):146-52 PMID: 10775454 SCOPUS ID: 2-s2.0-0034193163 04/25/2000       94 Citations
  • Direct EPR detection of the carbonate radical anion produced from peroxynitrite and carbon dioxide. (Bonini MG, Radi R, Ferrer-Sueta G, Ferreira AM, Augusto O) J Biol Chem 1999 Apr 16;274(16):10802-6 PMID: 10196155 SCOPUS ID: 2-s2.0-0033574624 04/10/1999       260 Citations
  • Last update: 08/27/2019
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