Medical College of Wisconsin
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Patricia A. Donohoue MD

Chief, Professor

Institution: Medical College of Wisconsin
Department: Pediatrics
Division: Endocrinology


  • Deletion of codons 88-92 of the melanocortin-4 receptor gene: a novel deleterious mutation in an obese female. (Donohoue PA, Tao YX, Collins M, Yeo GS, O'Rahilly S, Segaloff DL) J Clin Endocrinol Metab 2003 Dec;88(12):5841-5 PMID: 14671178 12/13/2003
  • A meta-analytic investigation of linkage and association of common leptin receptor (LEPR) polymorphisms with body mass index and waist circumference. (Heo M, Leibel RL, Fontaine KR, Boyer BB, Chung WK, Koulu M, Karvonen MK, Pesonen U, Rissanen A, Laakso M, Uusitupa MI, Chagnon Y, Bouchard C, Donohoue PA, Burns TL, Shuldiner AR, Silver K, Andersen RE, Pedersen O, Echwald S, Sørensen TI, Behn P, Permutt MA, Jacobs KB, Elston RC, Hoffman DJ, Gropp E, Allison DB) Int J Obes Relat Metab Disord 2002 May;26(5):640-6 PMID: 12032747 05/29/2002
  • Pooling analysis of genetic data: the association of leptin receptor (LEPR) polymorphisms with variables related to human adiposity. (Heo M, Leibel RL, Boyer BB, Chung WK, Koulu M, Karvonen MK, Pesonen U, Rissanen A, Laakso M, Uusitupa MI, Chagnon Y, Bouchard C, Donohoue PA, Burns TL, Shuldiner AR, Silver K, Andersen RE, Pedersen O, Echwald S, Sørensen TI, Behn P, Permutt MA, Jacobs KB, Elston RC, Hoffman DJ, Allison DB) Genetics 2001 Nov;159(3):1163-78 PMID: 11729160 PMCID: PMC1461868 12/01/2001
  • Sympathetic inhibition, leptin, and uncoupling protein subtype expression in normal fasting rats. (Sivitz WI, Fink BD, Morgan DA, Fox JM, Donohoue PA, Haynes WG) Am J Physiol 1999 Oct;277(4 Pt 1):E668-77 PMID: 10516126 10/12/1999
  • Fasting and leptin modulate adipose and muscle uncoupling protein: divergent effects between messenger ribonucleic acid and protein expression. (Sivitz WI, Fink BD, Donohoue PA) Endocrinology 1999 Apr;140(4):1511-9 PMID: 10098482 03/31/1999
  • Clinical and functional effects of mutations in the DAX-1 gene in patients with adrenal hypoplasia congenita. (Reutens AT, Achermann JC, Ito M, Ito M, Gu WX, Habiby RL, Donohoue PA, Pang S, Hindmarsh PC, Jameson JL) J Clin Endocrinol Metab 1999 Feb;84(2):504-11 PMID: 10022408 02/18/1999
  • E380D: a novel point mutation of CYP21 in an HLA-homozygous patient with salt-losing congenital adrenal hyperplasia due to 21-hydroxylase deficiency. (Kirby-Keyser L, Porter CC, Donohoue PA) Hum Mutat 1997;9(2):181-2 PMID: 9067760 01/01/1997
  • Phenotypic evolution of classic 21-hydroxylase deficiency. (Hoffman WH, Shin MY, Donohoue PA, Helman SW, Brown SL, Rosculet G, Mahesh VB) Clin Endocrinol (Oxf) 1996 Jul;45(1):103-9 PMID: 8796146 07/01/1996
  • Linkage of congenital isolated adrenocorticotropic hormone deficiency to the corticotropin releasing hormone locus using simple sequence repeat polymorphisms. (Kyllo JH, Collins MM, Vetter KL, Cuttler L, Rosenfield RL, Donohoue PA) Am J Med Genet 1996 Mar 29;62(3):262-7 PMID: 8882784 03/29/1996
  • Constitutive human steroid 21-hydroxylase promoter gene and pseudogene activity in steroidogenic and nonsteroidogenic cells with the luciferase gene as a reporter. (Kyllo JH, Collins MM, Donohoue PA) Endocr Res 1995 Nov;21(4):777-91 PMID: 8582328 11/01/1995
  • The HLA-A3, Cw6,B47,DR7 extended haplotypes in salt losing 21-hydroxylase deficiency and in the Old Order Amish: identical class I antigens and class II alleles with at least two crossover sites in the class III region. (Donohoue PA, Guethlein L, Collins MM, Van Dop C, Migeon CJ, Bias WB, Schmeckpeper BJ) Tissue Antigens 1995 Sep;46(3 ( Pt 1)):163-72 PMID: 8525475 09/01/1995
  • A new way to seal glass plates for denaturing gradient gel electrophoresis. (Kyllo JH, Kirby-Keyser L, Donohoue PA, Porter CC) Biotechniques 1994 May;16(5):792 PMID: 8068325 05/01/1994
  • The human complement C4B/steroid 21-hydroxylase (CYP21) and complement C4A/21-hydroxylase pseudogene (CYP21P) intergenic sequences: comparison and identification of possible regulatory elements. (Donohoue PA, Collins MM) Biochem Biophys Res Commun 1992 Jul 15;186(1):256-62 PMID: 1385946 07/15/1992
  • Pituitary gigantism caused by growth hormone excess from infancy. (Gelber SJ, Heffez DS, Donohoue PA) J Pediatr 1992 Jun;120(6):931-4 PMID: 1593354 06/01/1992
  • Accelerated growth rates in children treated with growth hormone after renal transplantation. (Van Dop C, Jabs KL, Donohoue PA, Bock GH, Fivush BA, Harmon WE) J Pediatr 1992 Feb;120(2 Pt 1):244-50 PMID: 1735820 02/01/1992
  • Congenital adrenal hyperplasia caused by 21-hydroxylase deficiency. Its molecular basis and its remaining therapeutic problems. (Migeon CJ, Donohoue PA) Endocrinol Metab Clin North Am 1991 Jun;20(2):277-96 PMID: 1879400 06/01/1991
  • Glucose tolerance in children with renal allografts and effect of growth hormone treatment. (Van Dop C, Donohoue PA, Jabs KL, Bock GH, Fivush BA, Harmon WE) J Pediatr 1991 May;118(5):708-14 PMID: 2019924 05/01/1991
  • Exon 7 Ncol restriction site within CYP21B (steroid 21-hydroxylase) is a normal polymorphism. (Donohoue PA, Sandrini Neto R, Collins MM, Migeon CJ) Mol Endocrinol 1990 Sep;4(9):1354-62 PMID: 1978247 09/01/1990
  • Endocrine evaluation of adults with mild hypospadias. (Gearhart JP, Donohoue PA, Brown TR, Walsh PC, Berkovitz GD) J Urol 1990 Aug;144(2 Pt 1):274-7 PMID: 2115596 08/01/1990
  • Enhanced growth with growth hormone therapy after renal transplantation. (Van Dop C, Donohoue PA, Bock GH, Ruley J) Pediatr Nephrol 1989 Oct;3(4):468-9 PMID: 2642119 10/01/1989
  • Two distinct areas of unequal crossingover within the steroid 21-hydroxylase genes produce absence of CYP21B. (Donohoue PA, Jospe N, Migeon CJ, Van Dop C) Genomics 1989 Oct;5(3):397-406 PMID: 2613228 10/01/1989
  • Serum 3 alpha-androstanediol glucuronide measurements in sexually mature women with congenital adrenal hyperplasia during therapy. (Reiner BJ, Donohoue PA, Migeon CJ, Berkovitz GD) J Clin Endocrinol Metab 1989 Jul;69(1):105-9 PMID: 2732292 07/01/1989
  • Restriction fragment analysis of duplication of the fourth component of complement (C4A). (McLean RH, Donohoue PA, Jospe N, Bias WB, Van Dop C, Migeon CJ) Genomics 1988 Jan;2(1):76-85 PMID: 2838414 01/01/1988
  • Coupling of HLA-A3,Cw6,Bw47,DR7 and a normal CA21HB steroid 21-hydroxylase gene in the Old Order Amish. (Donohoue PA, Van Dop C, Migeon CJ, McLean RH, Bias WB) J Clin Endocrinol Metab 1987 Nov;65(5):980-6 PMID: 2822757 11/01/1987
  • Prevalence of polymorphic 21-hydroxylase gene (CA21HB) mutations in salt-losing congenital adrenal hyperplasia. (Jospe N, Donohoue PA, Van Dop C, McLean RH, Bias WB, Migeon CJ) Biochem Biophys Res Commun 1987 Feb 13;142(3):798-804 PMID: 3030300 02/13/1987
  • Gene conversion in salt-losing congenital adrenal hyperplasia with absent complement C4B protein. (Donohoue PA, van Dop C, McLean RH, White PC, Jospe N, Migeon CJ) J Clin Endocrinol Metab 1986 May;62(5):995-1002 PMID: 3007562 05/01/1986
  • Restriction maps and restriction fragment length polymorphisms of the human 21-hydroxylase genes. (Donohoue PA, Jospe N, Migeon CJ, McLean RH, Bias WB, White PC, Van Dop C) Biochem Biophys Res Commun 1986 Apr 29;136(2):722-9 PMID: 3010994 04/29/1986
  • Congenital adrenal hyperplasia: molecular mechanisms resulting in 21-hydroxylase deficiency. (Donohoue PA, Van Dop C, Jospe N, Migeon CJ) Acta Endocrinol Suppl (Copenh) 1986;279:315-20 PMID: 3022524 01/01/1986
  • Last update: 09/13/2010
    jenkins-FCD Prod-29 84643b21e512b06ca32a9eea21e90ce5435f61b4