Medical College of Wisconsin
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Pengyuan Liu PhD

Adjunct Associate Professor

Institution: Medical College of Wisconsin
Department: Physiology
Program: Cancer Center

Member of the Cancer Center
Member of the Cardiovascular Center


Research Experience

  • Genome sequence analysis, Cancer genetics, Statistical genetics, Bioinformatics
  • Publications (94)

  • CircPLEKHM3 acts as a tumor suppressor through regulation of the miR-9/BRCA1/DNAJB6/KLF4/AKT1 axis in ovarian cancer. (Zhang L, Zhou Q, Qiu Q, Hou L, Wu M, Li J, Li X, Lu B, Cheng X, Liu P, Lu W, Lu Y) Mol Cancer 2019 10 17;18(1):144 PMID: 31623606 PMCID: PMC6796346 SCOPUS ID: 2-s2.0-85073621877 10/19/2019       10 Citations
  • Dietary Effects on Dahl Salt-Sensitive Hypertension, Renal Damage, and the T Lymphocyte Transcriptome. (Abais-Battad JM, Alsheikh AJ, Pan X, Fehrenbach DJ, Dasinger JH, Lund H, Roberts ML, Kriegel AJ, Cowley AW Jr, Kidambi S, Kotchen TA, Liu P, Liang M, Mattson DL) Hypertension 2019 10;74(4):854-863 PMID: 31476910 PMCID: PMC6739138 SCOPUS ID: 2-s2.0-85072134357 09/04/2019       4 Citations
  • Adverse early-life environment impairs postnatal lung development in mice. (Lai PY, Jing X, Michalkiewicz T, Entringer B, Ke X, Majnik A, Kriegel AJ, Liu P, Lane RH, Konduri GG) Physiol Genomics 2019 09 01;51(9):462-470 PMID: 31373541 PMCID: PMC6766700 SCOPUS ID: 2-s2.0-85072265843 08/03/2019       2 Citations
  • Long Noncoding RNA: Genomics and Relevance to Physiology. (Kong Y, Lu Z, Liu P, Liu Y, Wang F, Liang EY, Hou FF, Liang M) Compr Physiol 2019 06 12;9(3):933-946 PMID: 31187897 SCOPUS ID: 2-s2.0-85067798712 06/13/2019       5 Citations
  • DriverML: a machine learning algorithm for identifying driver genes in cancer sequencing studies. (Han Y, Yang J, Qian X, Cheng WC, Liu SH, Hua X, Zhou L, Yang Y, Wu Q, Liu P, Lu Y) Nucleic Acids Res 2019 05 07;47(8):e45 PMID: 30773592 PMCID: PMC6486576 SCOPUS ID: 2-s2.0-85068538022 02/19/2019       4 Citations
  • Salt-deficient diet exacerbates cystogenesis in ARPKD via epithelial sodium channel (ENaC). (Ilatovskaya DV, Levchenko V, Pavlov TS, Isaeva E, Klemens CA, Johnson J, Liu P, Kriegel AJ, Staruschenko A) EBioMedicine 2019 Feb;40:663-674 PMID: 30745171 PMCID: PMC6413684 SCOPUS ID: 2-s2.0-85061112508 02/13/2019       8 Citations
  • Role of DNA De Novo (De)Methylation in the Kidney in Salt-Induced Hypertension. (Liu P, Liu Y, Liu H, Pan X, Li Y, Usa K, Mishra MK, Nie J, Liang M) Hypertension 2018 11;72(5):1160-1171 PMID: 30354815 PMCID: PMC6314686 SCOPUS ID: 2-s2.0-85055596895 10/26/2018       5 Citations
  • MicroRNA-668 represses MTP18 to preserve mitochondrial dynamics in ischemic acute kidney injury. (Wei Q, Sun H, Song S, Liu Y, Liu P, Livingston MJ, Wang J, Liang M, Mi QS, Huo Y, Nahman NS, Mei C, Dong Z) J Clin Invest 2018 12 03;128(12):5448-5464 PMID: 30325740 PMCID: PMC6264638 SCOPUS ID: 2-s2.0-85058349510 10/17/2018       21 Citations
  • Smoker and non-smoker lung adenocarcinoma is characterized by distinct tumor immune microenvironments (Li X, Li J, Wu P, Zhou L, Lu B, Ying K, Chen E, Lu Y, Liu P) OncoImmunology 3 October 2018;7(10) SCOPUS ID: 2-s2.0-85051106729 10/03/2018    
  • Circ2Disease: a manually curated database of experimentally validated circRNAs in human disease. (Yao D, Zhang L, Zheng M, Sun X, Lu Y, Liu P) Sci Rep 2018 07 20;8(1):11018 PMID: 30030469 PMCID: PMC6054656 SCOPUS ID: 2-s2.0-85050626712 07/22/2018       16 Citations
  • Stability of global methylation profiles of whole blood and extracted DNA under different storage durations and conditions. (Li Y, Pan X, Roberts ML, Liu P, Kotchen TA, Cowley AW Jr, Mattson DL, Liu Y, Liang M, Kidambi S) Epigenomics 2018 06;10(6):797-811 PMID: 29683333 SCOPUS ID: 2-s2.0-85049644277 04/24/2018       6 Citations
  • Transcriptomic analysis reveals inflammatory and metabolic pathways that are regulated by renal perfusion pressure in the outer medulla of Dahl-S rats. (Evans LC, Dayton A, Yang C, Liu P, Kurth T, Ahn KW, Komas S, Stingo FC, Laud PW, Vannucci M, Liang M, Cowley AW Jr) Physiol Genomics 2018 06 01;50(6):440-447 PMID: 29602296 PMCID: PMC6032288 SCOPUS ID: 2-s2.0-85051123417 04/01/2018       2 Citations
  • A comprehensive evaluation of alignment software for reduced representation bisulfite sequencing data. (Sun X, Han Y, Zhou L, Chen E, Lu B, Liu Y, Pan X, Cowley AW Jr, Liang M, Wu Q, Lu Y, Liu P) Bioinformatics 2018 08 15;34(16):2715-2723 PMID: 29579198 SCOPUS ID: 2-s2.0-85055129630 03/27/2018       4 Citations
  • Urinary Metabolites Associated with Blood Pressure on a Low- or High-Sodium Diet. (Cheng Y, Song H, Pan X, Xue H, Wan Y, Wang T, Tian Z, Hou E, Lanza IR, Liu P, Liu Y, Laud PW, Usa K, He Y, Liang M) Theranostics 2018;8(6):1468-1480 PMID: 29556335 PMCID: PMC5858161 SCOPUS ID: 2-s2.0-85041571500 03/21/2018       8 Citations
  • Genome-wide map of proximity linkage to renin proximal promoter in rat. (Stodola TJ, Liu P, Liu Y, Vallejos AK, Geurts AM, Greene AS, Liang M) Physiol Genomics 2018 05 01;50(5):323-331 PMID: 29521603 PMCID: PMC6008118 SCOPUS ID: 2-s2.0-85061579448 03/10/2018       4 Citations
  • miR-29 contributes to normal endothelial function and can restore it in cardiometabolic disorders. (Widlansky ME, Jensen DM, Wang J, Liu Y, Geurts AM, Kriegel AJ, Liu P, Ying R, Zhang G, Casati M, Chu C, Malik M, Branum A, Tanner MJ, Tyagi S, Usa K, Liang M) EMBO Mol Med 2018 03;10(3) PMID: 29374012 PMCID: PMC5840545 SCOPUS ID: 2-s2.0-85041063208 01/28/2018       26 Citations
  • Artificial intelligence, physiological genomics, and precision medicine. (Williams AM, Liu Y, Regner KR, Jotterand F, Liu P, Liang M) Physiol Genomics 2018 04 01;50(4):237-243 PMID: 29373082 PMCID: PMC5966805 SCOPUS ID: 2-s2.0-85046104804 01/27/2018       13 Citations
  • Investigation of the Relationship Between Radiation Dose and Gene Mutations and Fusions in Post-Chernobyl Thyroid Cancer. (Efanov AA, Brenner AV, Bogdanova TI, Kelly LM, Liu P, Little MP, Wald AI, Hatch M, Zurnadzy LY, Nikiforova MN, Drozdovitch V, Leeman-Neill R, Mabuchi K, Tronko MD, Chanock SJ, Nikiforov YE) J Natl Cancer Inst 2018 04 01;110(4):371-378 PMID: 29165687 PMCID: PMC6059206 SCOPUS ID: 2-s2.0-85052518227 11/23/2017       14 Citations
  • MicroRNA-21 regulates peroxisome proliferator-activated receptor alpha, a molecular mechanism of cardiac pathology in Cardiorenal Syndrome Type 4. (Chuppa S, Liang M, Liu P, Liu Y, Casati MC, Cowley AW, Patullo L, Kriegel AJ) Kidney Int 2018 02;93(2):375-389 PMID: 28760335 PMCID: PMC5787401 SCOPUS ID: 2-s2.0-85026463717 08/02/2017       22 Citations
  • Tissue-Specific MicroRNA Expression Patterns in Four Types of Kidney Disease. (Baker MA, Davis SJ, Liu P, Pan X, Williams AM, Iczkowski KA, Gallagher ST, Bishop K, Regner KR, Liu Y, Liang M) J Am Soc Nephrol 2017 Oct;28(10):2985-2992 PMID: 28663230 PMCID: PMC5619963 SCOPUS ID: 2-s2.0-85030470491 07/01/2017       36 Citations
  • XRN2 promotes EMT and metastasis through regulating maturation of miR-10a. (Zhang H, Lu Y, Chen E, Li X, Lv B, Vikis HG, Liu P) Oncogene 2017 07 06;36(27):3925-3933 PMID: 28319071 SCOPUS ID: 2-s2.0-85015661507 03/21/2017       10 Citations
  • Changes in miRNA in the lung and whole blood after whole thorax irradiation in rats. (Gao F, Liu P, Narayanan J, Yang M, Fish BL, Liu Y, Liang M, Jacobs ER, Medhora M) Sci Rep 2017 03 17;7:44132 PMID: 28303893 PMCID: PMC5355888 SCOPUS ID: 2-s2.0-85015404996 03/18/2017       11 Citations
  • Identifying Candidate Genes that Underlie Cellular pH Sensitivity in Serotonin Neurons Using Transcriptomics: A Potential Role for Kir5.1 Channels. (Puissant MM, Mouradian GC Jr, Liu P, Hodges MR) Front Cell Neurosci 2017;11:34 PMID: 28270749 PMCID: PMC5318415 03/09/2017    
  • THADA fusion is a mechanism of IGF2BP3 activation and IGF1R signaling in thyroid cancer. (Panebianco F, Kelly LM, Liu P, Zhong S, Dacic S, Wang X, Singhi AD, Dhir R, Chiosea SI, Kuan SF, Bhargava R, Dabbs D, Trivedi S, Gandhi M, Diaz R, Wald AI, Carty SE, Ferris RL, Lee AV, Nikiforova MN, Nikiforov YE) Proc Natl Acad Sci U S A 2017 02 28;114(9):2307-2312 PMID: 28193878 PMCID: PMC5338560 SCOPUS ID: 2-s2.0-85014281044 02/15/2017       16 Citations
  • The β-TrCP-FBXW2-SKP2 axis regulates lung cancer cell growth with FBXW2 acting as a tumour suppressor. (Xu J, Zhou W, Yang F, Chen G, Li H, Zhao Y, Liu P, Li H, Tan M, Xiong X, Sun Y) Nat Commun 2017 01 16;8:14002 PMID: 28090088 PMCID: PMC5241824 SCOPUS ID: 2-s2.0-85009436123 01/17/2017       27 Citations
  • Targeted, Deep Sequencing Reveals Full Methylation Profiles of Multiple HPV Types and Potential Biomarkers for Cervical Cancer Progression. (Liu P, Iden M, Fye S, Huang YW, Hopp E, Chu C, Lu Y, Rader JS) Cancer Epidemiol Biomarkers Prev 2017 04;26(4):642-650 PMID: 28069683 SCOPUS ID: 2-s2.0-85016990220 01/11/2017       12 Citations
  • Whole-exome sequencing reveals genetic variants in ERC1 and KCNG4 associated with complete hydatidiform mole in Chinese Han women (Yu Y, Lu B, Lu W, Li S, Li X, Wang X, Wan X, Chen Y, Feng S, Jia Y, Yang R, Tang F, Li X, Zhang S, Wang X, Wei H, Peng Z, Lu L, Zhong H, Zhao L, Huang Z, Lin L, Shen W, Lu Y, Cao Z, Zou J, Ma Y, Chen X, Tian Q, Lu S, Liu P, Ma D, Xie X, Cheng X) Oncotarget 2017;8(43):75264-75271 SCOPUS ID: 2-s2.0-85030092130 01/01/2017    
  • Somatic Genomics and Clinical Features of Lung Adenocarcinoma: A Retrospective Study. (Shi J, Hua X, Zhu B, Ravichandran S, Wang M, Nguyen C, Brodie SA, Palleschi A, Alloisio M, Pariscenti G, Jones K, Zhou W, Bouk AJ, Boland J, Hicks B, Risch A, Bennett H, Luke BT, Song L, Duan J, Liu P, Kohno T, Chen Q, Meerzaman D, Marconett C, Laird-Offringa I, Mills I, Caporaso NE, Gail MH, Pesatori AC, Consonni D, Bertazzi PA, Chanock SJ, Landi MT) PLoS Med 2016 Dec;13(12):e1002162 PMID: 27923066 PMCID: PMC5140047 SCOPUS ID: 2-s2.0-85007551446 12/07/2016       27 Citations
  • Raphe gene expression changes implicate immune-related functions in ventilatory plasticity following carotid body denervation in rats. (Mouradian GC Jr, Liu P, Hodges MR) Exp Neurol 2017 Jan;287(Pt 2):102-112 PMID: 27132994 PMCID: PMC5086315 SCOPUS ID: 2-s2.0-84975152252 05/03/2016       2 Citations
  • MicroRNA-489 Induction by Hypoxia-Inducible Factor-1 Protects against Ischemic Kidney Injury. (Wei Q, Liu Y, Liu P, Hao J, Liang M, Mi QS, Chen JK, Dong Z) J Am Soc Nephrol 2016 09;27(9):2784-96 PMID: 26975439 PMCID: PMC5004659 SCOPUS ID: 2-s2.0-85006261234 03/16/2016       39 Citations
  • Pappa2 is linked to salt-sensitive hypertension in Dahl S rats. (Cowley AW Jr, Yang C, Kumar V, Lazar J, Jacob H, Geurts AM, Liu P, Dayton A, Kurth T, Liang M) Physiol Genomics 2016 Jan;48(1):62-72 PMID: 26534937 PMCID: PMC4757026 SCOPUS ID: 2-s2.0-84953280775 11/05/2015       17 Citations
  • Endogenous microRNAs in human microvascular endothelial cells regulate mRNAs encoded by hypertension-related genes. (Kriegel AJ, Baker MA, Liu Y, Liu P, Cowley AW Jr, Liang M) Hypertension 2015 Oct;66(4):793-9 PMID: 26283043 PMCID: PMC4567475 SCOPUS ID: 2-s2.0-84941199042 08/19/2015       49 Citations
  • deGPS is a powerful tool for detecting differential expression in RNA-sequencing studies. (Chu C, Fang Z, Hua X, Yang Y, Chen E, Cowley AW Jr, Liang M, Liu P, Lu Y) BMC Genomics 2015 Jun 13;16:455 PMID: 26070955 PMCID: PMC4465298 SCOPUS ID: 2-s2.0-84931273060 06/14/2015       8 Citations
  • Whole Genome Sequence of Multiple Myeloma-Prone C57BL/KaLwRij Mouse Strain Suggests the Origin of Disease Involves Multiple Cell Types. (Amend SR, Wilson WC, Chu L, Lu L, Liu P, Serie D, Su X, Xu Y, Wang D, Gramolini A, Wen XY, O'Neal J, Hurchla M, Vachon CM, Colditz G, Vij R, Weilbaecher KN, Tomasson MH) PLoS One 2015;10(5):e0127828 PMID: 26020268 PMCID: PMC4447437 SCOPUS ID: 2-s2.0-84932602156 05/29/2015       12 Citations
  • MicroRNA-135b Regulates Leucine Zipper Tumor Suppressor 1 in Cutaneous Squamous Cell Carcinoma. (Olasz EB, Seline LN, Schock AM, Duncan NE, Lopez A, Lazar J, Flister MJ, Lu Y, Liu P, Sokumbi O, Harwood CA, Proby CM, Neuburg M, Lazarova Z) PLoS One 2015;10(5):e0125412 PMID: 25938461 PMCID: PMC4418692 SCOPUS ID: 2-s2.0-84929084940 05/06/2015       17 Citations
  • Genome-wide epigenetic and proteomic analysis reveals altered Notch signaling in EPC dysfunction. (Karcher JR, Hoffmann BR, Liu P, Liu Y, Liang M, Greene AS) Physiol Rep 2015 Apr;3(4) PMID: 25921777 PMCID: PMC4425964 04/30/2015    
  • RNASeq-derived transcriptome comparisons reveal neuromodulatory deficiency in the CO₂ insensitive brown Norway rat. (Puissant MM, Echert AE, Yang C, Mouradian GC Jr, Novotny T, Liu P, Liang M, Hodges MR) J Physiol 2015 01 15;593(2):415-30 PMID: 25630262 PMCID: PMC4303386 SCOPUS ID: 2-s2.0-84921032820 01/30/2015       10 Citations
  • Maternal diet during gestation and lactation modifies the severity of salt-induced hypertension and renal injury in Dahl salt-sensitive rats. (Geurts AM, Mattson DL, Liu P, Cabacungan E, Skelton MM, Kurth TM, Yang C, Endres BT, Klotz J, Liang M, Cowley AW Jr) Hypertension 2015 Feb;65(2):447-55 PMID: 25452472 PMCID: PMC4289102 SCOPUS ID: 2-s2.0-84921562280 12/03/2014       37 Citations
  • Characteristics of long non-coding RNAs in the Brown Norway rat and alterations in the Dahl salt-sensitive rat. (Wang F, Li L, Xu H, Liu Y, Yang C, Cowley AW Jr, Wang N, Liu P, Liang M) Sci Rep 2014 Nov 21;4:7146 PMID: 25413633 PMCID: PMC4894415 SCOPUS ID: 2-s2.0-84923342198 11/22/2014       37 Citations
  • Improved rat genome gene prediction by integration of ESTs with RNA-Seq information. (Li L, Chen E, Yang C, Zhu J, Jayaraman P, De Pons J, Kaczorowski CC, Jacob HJ, Greene AS, Hodges MR, Cowley AW Jr, Liang M, Xu H, Liu P, Lu Y) Bioinformatics 2015 Jan 01;31(1):25-32 PMID: 25217576 PMCID: PMC4296142 SCOPUS ID: 2-s2.0-84922366358 09/14/2014       3 Citations
  • Prostate cancer risk locus at 8q24 as a regulatory hub by physical interactions with multiple genomic loci across the genome. (Du M, Yuan T, Schilter KF, Dittmar RL, Mackinnon A, Huang X, Tschannen M, Worthey E, Jacob H, Xia S, Gao J, Tillmans L, Lu Y, Liu P, Thibodeau SN, Wang L) Hum Mol Genet 2015 Jan 01;24(1):154-66 PMID: 25149474 PMCID: PMC4262497 SCOPUS ID: 2-s2.0-84922561546 08/26/2014       33 Citations
  • A phase Ib study of the effects of black raspberries on rectal polyps in patients with familial adenomatous polyposis. (Wang LS, Burke CA, Hasson H, Kuo CT, Molmenti CL, Seguin C, Liu P, Huang TH, Frankel WL, Stoner GD) Cancer Prev Res (Phila) 2014 Jul;7(7):666-74 PMID: 24764585 SCOPUS ID: 2-s2.0-84904320624 04/26/2014       48 Citations
  • Characterization of biological pathways associated with a 1.37 Mbp genomic region protective of hypertension in Dahl S rats. (Cowley AW Jr, Moreno C, Jacob HJ, Peterson CB, Stingo FC, Ahn KW, Liu P, Vannucci M, Laud PW, Reddy P, Lazar J, Evans L, Yang C, Kurth T, Liang M) Physiol Genomics 2014 Jun 01;46(11):398-410 PMID: 24714719 PMCID: PMC4042181 SCOPUS ID: 2-s2.0-84901718506 04/10/2014       15 Citations
  • Identification of the transforming STRN-ALK fusion as a potential therapeutic target in the aggressive forms of thyroid cancer. (Kelly LM, Barila G, Liu P, Evdokimova VN, Trivedi S, Panebianco F, Gandhi M, Carty SE, Hodak SP, Luo J, Dacic S, Yu YP, Nikiforova MN, Ferris RL, Altschuler DL, Nikiforov YE) Proc Natl Acad Sci U S A 2014 Mar 18;111(11):4233-8 PMID: 24613930 PMCID: PMC3964116 SCOPUS ID: 2-s2.0-84896531092 03/13/2014       138 Citations
  • Cancer genomics: new software tools making sequencing more accessible. (Chen EG, Liu P, Lu Y) Per Med 2014 Mar;11(2):127-130 PMID: 29751375 03/01/2014    
  • Whole-genome sequencing identifies genomic heterogeneity at a nucleotide and chromosomal level in bladder cancer. (Morrison CD, Liu P, Woloszynska-Read A, Zhang J, Luo W, Qin M, Bshara W, Conroy JM, Sabatini L, Vedell P, Xiong D, Liu S, Wang J, Shen H, Li Y, Omilian AR, Hill A, Head K, Guru K, Kunnev D, Leach R, Eng KH, Darlak C, Hoeflich C, Veeranki S, Glenn S, You M, Pruitt SC, Johnson CS, Trump DL) Proc Natl Acad Sci U S A 2014 Feb 11;111(6):E672-81 PMID: 24469795 PMCID: PMC3926024 SCOPUS ID: 2-s2.0-84893848638 01/29/2014       61 Citations
  • Base-resolution maps of 5-methylcytosine and 5-hydroxymethylcytosine in Dahl S rats: effect of salt and genomic sequence. (Liu Y, Liu P, Yang C, Cowley AW Jr, Liang M) Hypertension 2014 Apr;63(4):827-38 PMID: 24420542 PMCID: PMC4315612 SCOPUS ID: 2-s2.0-84897061863 01/15/2014       44 Citations
  • ETV6-NTRK3 is a common chromosomal rearrangement in radiation-associated thyroid cancer. (Leeman-Neill RJ, Kelly LM, Liu P, Brenner AV, Little MP, Bogdanova TI, Evdokimova VN, Hatch M, Zurnadzy LY, Nikiforova MN, Yue NJ, Zhang M, Mabuchi K, Tronko MD, Nikiforov YE) Cancer 2014 Mar 15;120(6):799-807 PMID: 24327398 PMCID: PMC3947712 SCOPUS ID: 2-s2.0-84896723858 12/12/2013       144 Citations
  • EYA4 is inactivated biallelically at a high frequency in sporadic lung cancer and is associated with familial lung cancer risk. (Wilson IM, Vucic EA, Enfield KS, Thu KL, Zhang YA, Chari R, Lockwood WW, Radulovich N, Starczynowski DT, Banáth JP, Zhang M, Pusic A, Fuller M, Lonergan KM, Rowbotham D, Yee J, English JC, Buys TP, Selamat SA, Laird-Offringa IA, Liu P, Anderson M, You M, Tsao MS, Brown CJ, Bennewith KL, MacAulay CE, Karsan A, Gazdar AF, Lam S, Lam WL) Oncogene 2014 Sep 04;33(36):4464-73 PMID: 24096489 PMCID: PMC4527534 SCOPUS ID: 2-s2.0-84884967805 10/08/2013       23 Citations
  • Characteristics of microRNAs enriched in specific cell types and primary tissue types in solid organs. (Kriegel AJ, Liu Y, Liu P, Baker MA, Hodges MR, Hua X, Liang M) Physiol Genomics 2013 Dec 01;45(23):1144-56 PMID: 24085797 PMCID: PMC3882707 SCOPUS ID: 2-s2.0-84888802105 10/03/2013       17 Citations
  • Concordant effects of aromatase inhibitors on gene expression in ER+ Rat and human mammary cancers and modulation of the proteins coded by these genes. (Lu Y, You M, Ghazoui Z, Liu P, Vedell PT, Wen W, Bode AM, Grubbs CJ, Lubet RA) Cancer Prev Res (Phila) 2013 Nov;6(11):1151-61 PMID: 24067424 PMCID: PMC3874590 SCOPUS ID: 2-s2.0-84887878472 09/27/2013       8 Citations
  • Targeting the endothelial progenitor cell surface proteome to identify novel mechanisms that mediate angiogenic efficacy in a rodent model of vascular disease. (Kaczorowski CC, Stodola TJ, Hoffmann BR, Prisco AR, Liu PY, Didier DN, Karcher JR, Liang M, Jacob HJ, Greene AS) Physiol Genomics 2013 Nov 01;45(21):999-1011 PMID: 24022221 PMCID: PMC3841789 SCOPUS ID: 2-s2.0-84887110240 09/12/2013       13 Citations
  • DrGaP: a powerful tool for identifying driver genes and pathways in cancer sequencing studies. (Hua X, Xu H, Yang Y, Zhu J, Liu P, Lu Y) Am J Hum Genet 2013 Sep 05;93(3):439-51 PMID: 23954162 PMCID: PMC3769934 SCOPUS ID: 2-s2.0-84883799242 08/21/2013       40 Citations
  • Functional genomic assessment of phosgene-induced acute lung injury in mice. (Leikauf GD, Concel VJ, Bein K, Liu P, Berndt A, Martin TM, Ganguly K, Jang AS, Brant KA, Dopico RA Jr, Upadhyay S, Cario C, Di YP, Vuga LJ, Kostem E, Eskin E, You M, Kaminski N, Prows DR, Knoell DL, Fabisiak JP) Am J Respir Cell Mol Biol 2013 Sep;49(3):368-83 PMID: 23590305 PMCID: PMC3824050 SCOPUS ID: 2-s2.0-84883477803 04/18/2013       14 Citations
  • Increased proliferative cells in the medullary thick ascending limb of the loop of Henle in the Dahl salt-sensitive rat. (Yang C, Stingo FC, Ahn KW, Liu P, Vannucci M, Laud PW, Skelton M, O'Connor P, Kurth T, Ryan RP, Moreno C, Tsaih SW, Patone G, Hummel O, Jacob HJ, Liang M, Cowley AW Jr) Hypertension 2013 Jan;61(1):208-15 PMID: 23184381 PMCID: PMC3760736 SCOPUS ID: 2-s2.0-84871619201 11/28/2012       17 Citations
  • WNT1-inducible signaling pathway protein 1 contributes to ventilator-induced lung injury. (Li HH, Li Q, Liu P, Liu Y, Li J, Wasserloos K, Chao W, You M, Oury TD, Chhinder S, Hackam DJ, Billiar TR, Leikauf GD, Pitt BR, Zhang LM) Am J Respir Cell Mol Biol 2012 Oct;47(4):528-35 PMID: 22700866 PMCID: PMC3488625 SCOPUS ID: 2-s2.0-84867025205 06/16/2012       26 Citations
  • Exome sequencing identifies MXRA5 as a novel cancer gene frequently mutated in non-small cell lung carcinoma from Chinese patients. (Xiong D, Li G, Li K, Xu Q, Pan Z, Ding F, Vedell P, Liu P, Cui P, Hua X, Jiang H, Yin Y, Zhu Z, Li X, Zhang B, Ma D, Wang Y, You M) Carcinogenesis 2012 Sep;33(9):1797-805 PMID: 22696596 PMCID: PMC3514907 SCOPUS ID: 2-s2.0-84865569656 06/15/2012       35 Citations
  • Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing. (Liu P, Morrison C, Wang L, Xiong D, Vedell P, Cui P, Hua X, Ding F, Lu Y, James M, Ebben JD, Xu H, Adjei AA, Head K, Andrae JW, Tschannen MR, Jacob H, Pan J, Zhang Q, Van den Bergh F, Xiao H, Lo KC, Patel J, Richmond T, Watt MA, Albert T, Selzer R, Anderson M, Wang J, Wang Y, Starnes S, Yang P, You M) Carcinogenesis 2012 Jul;33(7):1270-6 PMID: 22510280 PMCID: PMC3499051 SCOPUS ID: 2-s2.0-84865168855 04/19/2012       127 Citations
  • Integrative assessment of chlorine-induced acute lung injury in mice. (Leikauf GD, Pope-Varsalona H, Concel VJ, Liu P, Bein K, Berndt A, Martin TM, Ganguly K, Jang AS, Brant KA, Dopico RA Jr, Upadhyay S, Di YP, Li Q, Hu Z, Vuga LJ, Medvedovic M, Kaminski N, You M, Alexander DC, McDunn JE, Prows DR, Knoell DL, Fabisiak JP) Am J Respir Cell Mol Biol 2012 Aug;47(2):234-44 PMID: 22447970 PMCID: PMC3423464 SCOPUS ID: 2-s2.0-84864572505 03/27/2012       20 Citations
  • MicroRNA profiling and prediction of recurrence/relapse-free survival in stage I lung cancer. (Lu Y, Govindan R, Wang L, Liu PY, Goodgame B, Wen W, Sezhiyan A, Pfeifer J, Li YF, Hua X, Wang Y, Yang P, You M) Carcinogenesis 2012 May;33(5):1046-54 PMID: 22331473 PMCID: PMC3334512 SCOPUS ID: 2-s2.0-84860466755 02/15/2012       114 Citations
  • Gene-expression signature predicts postoperative recurrence in stage I non-small cell lung cancer patients. (Lu Y, Wang L, Liu P, Yang P, You M) PLoS One 2012;7(1):e30880 PMID: 22292069 PMCID: PMC3264655 SCOPUS ID: 2-s2.0-84856116589 02/01/2012       30 Citations
  • Genome-wide association and fine mapping of genetic loci predisposing to colon carcinogenesis in mice. (Liu P, Lu Y, Liu H, Wen W, Jia D, Wang Y, You M) Mol Cancer Res 2012 Jan;10(1):66-74 PMID: 22127497 SCOPUS ID: 2-s2.0-84862934081 12/01/2011       21 Citations
  • Neutrophils are required for 3-methylcholanthrene-initiated, butylated hydroxytoluene-promoted lung carcinogenesis. (Vikis HG, Gelman AE, Franklin A, Stein L, Rymaszewski A, Zhu J, Liu P, Tichelaar JW, Krupnick AS, You M) Mol Carcinog 2012 Dec;51(12):993-1002 PMID: 22006501 PMCID: PMC3389580 SCOPUS ID: 2-s2.0-84867746013 10/19/2011       12 Citations
  • Modulation of gene expression and cell-cycle signaling pathways by the EGFR inhibitor gefitinib (Iressa) in rat urinary bladder cancer. (Lu Y, Liu P, Van den Bergh F, Zellmer V, James M, Wen W, Grubbs CJ, Lubet RA, You M) Cancer Prev Res (Phila) 2012 Feb;5(2):248-59 PMID: 21982874 SCOPUS ID: 2-s2.0-84863237623 10/11/2011       13 Citations
  • Principles for the post-GWAS functional characterization of cancer risk loci. (Freedman ML, Monteiro AN, Gayther SA, Coetzee GA, Risch A, Plass C, Casey G, De Biasi M, Carlson C, Duggan D, James M, Liu P, Tichelaar JW, Vikis HG, You M, Mills IG) Nat Genet 2011 Jun;43(6):513-8 PMID: 21614091 PMCID: PMC3325768 SCOPUS ID: 2-s2.0-79957604678 05/27/2011       278 Citations
  • Haplotype association mapping of acute lung injury in mice implicates activin a receptor, type 1. (Leikauf GD, Concel VJ, Liu P, Bein K, Berndt A, Ganguly K, Jang AS, Brant KA, Dietsch M, Pope-Varsalona H, Dopico RA Jr, Di YP, Li Q, Vuga LJ, Medvedovic M, Kaminski N, You M, Prows DR) Am J Respir Crit Care Med 2011 Jun 01;183(11):1499-509 PMID: 21297076 PMCID: PMC3137140 SCOPUS ID: 2-s2.0-79957969914 02/08/2011       29 Citations
  • Aerosolized bexarotene inhibits lung tumorigenesis without increasing plasma triglyceride and cholesterol levels in mice. (Zhang Q, Pan J, Zhang J, Liu P, Chen R, Chen DR, Lubet R, Wang Y, You M) Cancer Prev Res (Phila) 2011 Feb;4(2):270-6 PMID: 21163938 SCOPUS ID: 2-s2.0-79551709612 12/18/2010       18 Citations
  • Cross-species comparison of orthologous gene expression in human bladder cancer and carcinogen-induced rodent models. (Lu Y, Liu P, Wen W, Grubbs CJ, Townsend RR, Malone JP, Lubet RA, You M) Am J Transl Res 2010 Sep 20;3(1):8-27 PMID: 21139803 PMCID: PMC2981423 12/09/2010    
  • Multivariate Analysis of Microarray Data Using Hotelling's T 2 Test (Lu Y, Liu PY, Deng HW) Medical Biostatistics for Complex Diseases 19 July 2010:113-130 SCOPUS ID: 2-s2.0-84887108784 07/19/2010    
  • Functional genomics of chlorine-induced acute lung injury in mice. (Leikauf GD, Pope-Varsalona H, Concel VJ, Liu P, Bein K, Brant KA, Dopico RA, Di YP, Jang AS, Dietsch M, Medvedovic M, Li Q, Vuga LJ, Kaminski N, You M, Prows DR) Proc Am Thorac Soc 2010 Jul;7(4):294-6 PMID: 20601635 PMCID: PMC3136967 SCOPUS ID: 2-s2.0-77957903593 07/06/2010       8 Citations
  • A second genetic variant on chromosome 15q24-25.1 associates with lung cancer. (Liu P, Yang P, Wu X, Vikis HG, Lu Y, Wang Y, Schwartz AG, Pinney SM, de Andrade M, Gazdar A, Gaba C, Mandal D, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Spitz M, Amos CI, Anderson MW, You M) Cancer Res 2010 Apr 15;70(8):3128-35 PMID: 20395203 PMCID: PMC3378320 SCOPUS ID: 2-s2.0-77951049337 04/17/2010       4 Citations
  • Cumulative effect of multiple loci on genetic susceptibility to familial lung cancer. (Liu P, Vikis HG, Lu Y, Wang Y, Schwartz AG, Pinney SM, Yang P, de Andrade M, Gazdar A, Gaba C, Mandal D, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Amos CI, Anderson MW, You M) Cancer Epidemiol Biomarkers Prev 2010 Feb;19(2):517-24 PMID: 20142248 PMCID: PMC2846747 SCOPUS ID: 2-s2.0-76149107483 02/10/2010       24 Citations
  • Genetic variants cis-regulating Xrn2 expression contribute to the risk of spontaneous lung tumor. (Lu Y, Liu P, James M, Vikis HG, Liu H, Wen W, Franklin A, You M) Oncogene 2010 Feb 18;29(7):1041-9 PMID: 19915612 PMCID: PMC6019621 SCOPUS ID: 2-s2.0-77149169733 11/17/2009       15 Citations
  • Haplotype and cell proliferation analyses of candidate lung cancer susceptibility genes on chromosome 15q24-25.1. (Liu Y, Liu P, Wen W, James MA, Wang Y, Bailey-Wilson JE, Amos CI, Pinney SM, Yang P, de Andrade M, Petersen GM, Wiest JS, Fain PR, Schwartz AG, Gazdar A, Gaba C, Rothschild H, Mandal D, Kupert E, Lee J, Seminara D, Minna J, Anderson MW, You M) Cancer Res 2009 Oct 01;69(19):7844-50 PMID: 19789337 PMCID: PMC2846106 SCOPUS ID: 2-s2.0-70350215708 10/01/2009       37 Citations
  • Identification of Las2, a major modifier gene affecting the Pas1 mouse lung tumor susceptibility locus. (Liu PY, Vikis H, James M, Lu Y, Wang DL, Liu HB, Wen WD, Wang Y, You M) Cancer Res 2009 Aug 01;69(15):6290-8 PMID: 19622765 SCOPUS ID: 2-s2.0-68049120471 07/23/2009       6 Citations
  • Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5. (Wang JC, Cruchaga C, Saccone NL, Bertelsen S, Liu P, Budde JP, Duan W, Fox L, Grucza RA, Kern J, Mayo K, Reyes O, Rice J, Saccone SF, Spiegel N, Steinbach JH, Stitzel JA, Anderson MW, You M, Stevens VL, Bierut LJ, Goate AM, COGEND collaborators and GELCC collaborators) Hum Mol Genet 2009 Aug 15;18(16):3125-35 PMID: 19443489 PMCID: PMC2714722 SCOPUS ID: 2-s2.0-68049090045 05/16/2009       133 Citations
  • Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 as a likely candidate gene. (You M, Wang D, Liu P, Vikis H, James M, Lu Y, Wang Y, Wang M, Chen Q, Jia D, Liu Y, Wen W, Yang P, Sun Z, Pinney SM, Zheng W, Shu XO, Long J, Gao YT, Xiang YB, Chow WH, Rothman N, Petersen GM, de Andrade M, Wu Y, Cunningham JM, Wiest JS, Fain PR, Schwartz AG, Girard L, Gazdar A, Gaba C, Rothschild H, Mandal D, Coons T, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Amos CI, Anderson MW) Clin Cancer Res 2009 Apr 15;15(8):2666-74 PMID: 19351763 PMCID: PMC2746091 SCOPUS ID: 2-s2.0-65249131768 04/09/2009       59 Citations
  • Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer. (Liu P, Vikis HG, Wang D, Lu Y, Wang Y, Schwartz AG, Pinney SM, Yang P, de Andrade M, Petersen GM, Wiest JS, Fain PR, Gazdar A, Gaba C, Rothschild H, Mandal D, Coons T, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Wu X, Spitz MR, Eisen T, Houlston RS, Amos CI, Anderson MW, You M) J Natl Cancer Inst 2008 Sep 17;100(18):1326-30 PMID: 18780872 PMCID: PMC2538550 SCOPUS ID: 2-s2.0-52449127998 09/11/2008       113 Citations
  • Common human cancer genes discovered by integrated gene-expression analysis. (Lu Y, Yi Y, Liu P, Wen W, James M, Wang D, You M) PLoS One 2007 Nov 07;2(11):e1149 PMID: 17989776 PMCID: PMC2065803 SCOPUS ID: 2-s2.0-41149106140 11/09/2007       61 Citations
  • Large-scale in silico mapping of complex quantitative traits in inbred mice. (Liu P, Vikis H, Lu Y, Wang D, You M) PLoS One 2007 Jul 25;2(7):e651 PMID: 17653278 PMCID: PMC1920557 SCOPUS ID: 2-s2.0-38549083432 07/27/2007       31 Citations
  • A gene expression signature predicts survival of patients with stage I non-small cell lung cancer. (Lu Y, Lemon W, Liu PY, Yi Y, Morrison C, Yang P, Sun Z, Szoke J, Gerald WL, Watson M, Govindan R, You M) PLoS Med 2006 Dec;3(12):e467 PMID: 17194181 PMCID: PMC1716187 SCOPUS ID: 2-s2.0-33845877973 12/30/2006       229 Citations
  • Candidate lung tumor susceptibility genes identified through whole-genome association analyses in inbred mice. (Liu P, Wang Y, Vikis H, Maciag A, Wang D, Lu Y, Liu Y, You M) Nat Genet 2006 Aug;38(8):888-95 PMID: 16862160 SCOPUS ID: 2-s2.0-33746556713 07/25/2006       65 Citations
  • Accurate haplotype inference for multiple linked single-nucleotide polymorphisms using sibship data. (Liu PY, Lu Y, Deng HW) Genetics 2006 Sep;174(1):499-509 PMID: 16783022 PMCID: PMC1569787 SCOPUS ID: 2-s2.0-33748917422 06/20/2006       7 Citations
  • Impacts of QTL x environment interactions on genetic response to marker-assisted selection. (Liu PY, Zhu J, Yan L) Yi Chuan Xue Bao 2006 Jan;33(1):63-71 PMID: 16450589 SCOPUS ID: 2-s2.0-31344451887 02/03/2006       7 Citations
  • Improvement of mapping accuracy by unifying linkage and association analysis. (Lou XY, Ma JZ, Yang MC, Zhu J, Liu PY, Deng HW, Elston RC, Li MD) Genetics 2006 Jan;172(1):647-61 PMID: 16172505 PMCID: PMC1456190 SCOPUS ID: 2-s2.0-33644748167 09/21/2005       5 Citations
  • Hotelling's T2 multivariate profiling for detecting differential expression in microarrays. (Lu Y, Liu PY, Xiao P, Deng HW) Bioinformatics 2005 Jul 15;21(14):3105-13 PMID: 15905280 SCOPUS ID: 2-s2.0-25144474547 05/21/2005       70 Citations
  • A survey of haplotype variants at several disease candidate genes: the importance of rare variants for complex diseases. (Liu PY, Zhang YY, Lu Y, Long JR, Shen H, Zhao LJ, Xu FH, Xiao P, Xiong DH, Liu YJ, Recker RR, Deng HW) J Med Genet 2005 Mar;42(3):221-7 PMID: 15744035 PMCID: PMC1736011 SCOPUS ID: 2-s2.0-20144371261 03/04/2005       41 Citations
  • A two-step strategy for detecting differential gene expression in cDNA microarray data. (Lu Y, Zhu J, Liu P) Curr Genet 2005 Feb;47(2):121-31 PMID: 15688252 SCOPUS ID: 2-s2.0-13644271264 02/03/2005       9 Citations
  • Common variants at the PCOL2 and Sp1 binding sites of the COL1A1 gene and their interactive effect influence bone mineral density in Caucasians. (Liu PY, Lu Y, Long JR, Xu FH, Shen H, Recker RR, Deng HW) J Med Genet 2004 Oct;41(10):752-7 PMID: 15466008 PMCID: PMC1735608 SCOPUS ID: 2-s2.0-6344239056 10/07/2004       43 Citations
  • Quantifying the relationship between gene expressions and trait values in general pedigrees. (Lu Y, Liu PY, Liu YJ, Xu FH, Deng HW) Genetics 2004 Dec;168(4):2395-405 PMID: 15371358 PMCID: PMC1448709 SCOPUS ID: 2-s2.0-11244292074 09/17/2004       5 Citations
  • Marker-assisted selection in segregating generations of self-fertilizing crops. (Liu P, Zhu J, Lu Y) Theor Appl Genet 2004 Jul;109(2):370-6 PMID: 15069599 SCOPUS ID: 2-s2.0-4043183301 04/08/2004       29 Citations
  • Robust indices of Hardy-Weinberg disequilibrium for QTL fine mapping. (Deng HW, Li YM, Li MX, Liu PY) Hum Hered 2003;56(4):160-5 PMID: 15031618 SCOPUS ID: 2-s2.0-1642635110 03/20/2004       4 Citations
  • Complex segregation analyses of bone mineral density in Chinese. (Liu PY, Qin YJ, Zhou Q, Recker RR, Deng HW) Ann Hum Genet 2004 Mar;68(Pt 2):154-64 PMID: 15008794 03/11/2004       18 Citations
  • A method for marker-assisted selection based on QTLs with epistatic effects. (Liu P, Zhu J, Lou X, Lu Y) Genetica 2003 Sep;119(1):75-86 PMID: 12903749 SCOPUS ID: 2-s2.0-0038717858 08/09/2003       24 Citations
  • Last update: 11/28/2019
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