Medical College of Wisconsin
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Pengyuan Liu PhD

Adjunct Associate Professor

Institution: Medical College of Wisconsin
Department: Physiology
Program: Cancer Center

Member of the Cancer Center
Member of the Cardiovascular Center


Research Experience

  • Genome sequence analysis, Cancer genetics, Statistical genetics, Bioinformatics
  • Publications

  • Role of DNA De Novo (De)Methylation in the Kidney in Salt-Induced Hypertension. (Liu P, Liu Y, Liu H, Pan X, Li Y, Usa K, Mishra MK, Nie J, Liang M) Hypertension 2018 Nov;72(5):1160-1171 PMID: 30354815 PMCID: PMC6314686 10/26/2018    
  • Stability of global methylation profiles of whole blood and extracted DNA under different storage durations and conditions. (Li Y, Pan X, Roberts ML, Liu P, Kotchen TA, Cowley AW Jr, Mattson DL, Liu Y, Liang M, Kidambi S) Epigenomics 2018 06;10(6):797-811 PMID: 29683333 04/24/2018    
  • Transcriptomic analysis reveals inflammatory and metabolic pathways that are regulated by renal perfusion pressure in the outer medulla of Dahl-S rats. (Evans LC, Dayton A, Yang C, Liu P, Kurth T, Ahn KW, Komas S, Stingo FC, Laud PW, Vannucci M, Liang M, Cowley AW Jr) Physiol Genomics 2018 Jun 01;50(6):440-447 PMID: 29602296 PMCID: PMC6032288 04/01/2018    
  • A comprehensive evaluation of alignment software for reduced representation bisulfite sequencing data. (Sun X, Han Y, Zhou L, Chen E, Lu B, Liu Y, Pan X, Cowley AW Jr, Liang M, Wu Q, Lu Y, Liu P) Bioinformatics 2018 Aug 15;34(16):2715-2723 PMID: 29579198 03/27/2018    
  • Urinary Metabolites Associated with Blood Pressure on a Low- or High-Sodium Diet. (Cheng Y, Song H, Pan X, Xue H, Wan Y, Wang T, Tian Z, Hou E, Lanza IR, Liu P, Liu Y, Laud PW, Usa K, He Y, Liang M) Theranostics 2018;8(6):1468-1480 PMID: 29556335 PMCID: PMC5858161 03/21/2018    
  • Genome-wide map of proximity linkage to renin proximal promoter in rat. (Stodola TJ, Liu P, Liu Y, Vallejos AK, Geurts AM, Greene AS, Liang M) Physiol Genomics 2018 May 01;50(5):323-331 PMID: 29521603 PMCID: PMC6008118 03/10/2018    
  • miR-29 contributes to normal endothelial function and can restore it in cardiometabolic disorders. (Widlansky ME, Jensen DM, Wang J, Liu Y, Geurts AM, Kriegel AJ, Liu P, Ying R, Zhang G, Casati M, Chu C, Malik M, Branum A, Tanner MJ, Tyagi S, Usa K, Liang M) EMBO Mol Med 2018 03;10(3) PMID: 29374012 PMCID: PMC5840545 01/28/2018       7 Citations
  • Artificial intelligence, physiological genomics, and precision medicine. (Williams AM, Liu Y, Regner KR, Jotterand F, Liu P, Liang M) Physiol Genomics 2018 Apr 01;50(4):237-243 PMID: 29373082 PMCID: PMC5966805 01/27/2018       2 Citations
  • MicroRNA-21 regulates peroxisome proliferator-activated receptor alpha, a molecular mechanism of cardiac pathology in Cardiorenal Syndrome Type 4. (Chuppa S, Liang M, Liu P, Liu Y, Casati MC, Cowley AW, Patullo L, Kriegel AJ) Kidney Int 2018 02;93(2):375-389 PMID: 28760335 PMCID: PMC5787401 08/02/2017       3 Citations
  • Tissue-Specific MicroRNA Expression Patterns in Four Types of Kidney Disease. (Baker MA, Davis SJ, Liu P, Pan X, Williams AM, Iczkowski KA, Gallagher ST, Bishop K, Regner KR, Liu Y, Liang M) J Am Soc Nephrol 2017 Oct;28(10):2985-2992 PMID: 28663230 PMCID: PMC5619963 07/01/2017       11 Citations
  • Changes in miRNA in the lung and whole blood after whole thorax irradiation in rats. (Gao F, Liu P, Narayanan J, Yang M, Fish BL, Liu Y, Liang M, Jacobs ER, Medhora M) Sci Rep 2017 03 17;7:44132 PMID: 28303893 PMCID: PMC5355888 03/18/2017       3 Citations
  • Identifying Candidate Genes that Underlie Cellular pH Sensitivity in Serotonin Neurons Using Transcriptomics: A Potential Role for Kir5.1 Channels. (Puissant MM, Mouradian GC Jr, Liu P, Hodges MR) Front Cell Neurosci 2017;11:34 PMID: 28270749 PMCID: PMC5318415 03/09/2017    
  • Targeted, Deep Sequencing Reveals Full Methylation Profiles of Multiple HPV Types and Potential Biomarkers for Cervical Cancer Progression. (Liu P, Iden M, Fye S, Huang YW, Hopp E, Chu C, Lu Y, Rader JS) Cancer Epidemiol Biomarkers Prev 2017 04;26(4):642-650 PMID: 28069683 01/11/2017       9 Citations
  • Somatic Genomics and Clinical Features of Lung Adenocarcinoma: A Retrospective Study. (Shi J, Hua X, Zhu B, Ravichandran S, Wang M, Nguyen C, Brodie SA, Palleschi A, Alloisio M, Pariscenti G, Jones K, Zhou W, Bouk AJ, Boland J, Hicks B, Risch A, Bennett H, Luke BT, Song L, Duan J, Liu P, Kohno T, Chen Q, Meerzaman D, Marconett C, Laird-Offringa I, Mills I, Caporaso NE, Gail MH, Pesatori AC, Consonni D, Bertazzi PA, Chanock SJ, Landi MT) PLoS Med 2016 Dec;13(12):e1002162 PMID: 27923066 PMCID: PMC5140047 12/07/2016       15 Citations
  • Raphe gene expression changes implicate immune-related functions in ventilatory plasticity following carotid body denervation in rats. (Mouradian GC Jr, Liu P, Hodges MR) Exp Neurol 2017 Jan;287(Pt 2):102-112 PMID: 27132994 PMCID: PMC5086315 05/03/2016    
  • MicroRNA-489 Induction by Hypoxia-Inducible Factor-1 Protects against Ischemic Kidney Injury. (Wei Q, Liu Y, Liu P, Hao J, Liang M, Mi QS, Chen JK, Dong Z) J Am Soc Nephrol 2016 09;27(9):2784-96 PMID: 26975439 PMCID: PMC5004659 03/16/2016       22 Citations
  • Pappa2 is linked to salt-sensitive hypertension in Dahl S rats. (Cowley AW Jr, Yang C, Kumar V, Lazar J, Jacob H, Geurts AM, Liu P, Dayton A, Kurth T, Liang M) Physiol Genomics 2016 Jan;48(1):62-72 PMID: 26534937 PMCID: PMC4757026 11/05/2015       10 Citations
  • Endogenous microRNAs in human microvascular endothelial cells regulate mRNAs encoded by hypertension-related genes. (Kriegel AJ, Baker MA, Liu Y, Liu P, Cowley AW Jr, Liang M) Hypertension 2015 Oct;66(4):793-9 PMID: 26283043 PMCID: PMC4567475 08/19/2015       32 Citations
  • deGPS is a powerful tool for detecting differential expression in RNA-sequencing studies. (Chu C, Fang Z, Hua X, Yang Y, Chen E, Cowley AW Jr, Liang M, Liu P, Lu Y) BMC Genomics 2015 Jun 13;16:455 PMID: 26070955 PMCID: PMC4465298 06/14/2015       3 Citations
  • Whole Genome Sequence of Multiple Myeloma-Prone C57BL/KaLwRij Mouse Strain Suggests the Origin of Disease Involves Multiple Cell Types. (Amend SR, Wilson WC, Chu L, Lu L, Liu P, Serie D, Su X, Xu Y, Wang D, Gramolini A, Wen XY, O'Neal J, Hurchla M, Vachon CM, Colditz G, Vij R, Weilbaecher KN, Tomasson MH) PLoS One 2015;10(5):e0127828 PMID: 26020268 PMCID: PMC4447437 05/29/2015       10 Citations
  • MicroRNA-135b Regulates Leucine Zipper Tumor Suppressor 1 in Cutaneous Squamous Cell Carcinoma. (Olasz EB, Seline LN, Schock AM, Duncan NE, Lopez A, Lazar J, Flister MJ, Lu Y, Liu P, Sokumbi O, Harwood CA, Proby CM, Neuburg M, Lazarova Z) PLoS One 2015;10(5):e0125412 PMID: 25938461 PMCID: PMC4418692 05/06/2015       14 Citations
  • Genome-wide epigenetic and proteomic analysis reveals altered Notch signaling in EPC dysfunction. (Karcher JR, Hoffmann BR, Liu P, Liu Y, Liang M, Greene AS) Physiol Rep 2015 Apr;3(4) PMID: 25921777 PMCID: PMC4425964 04/30/2015    
  • RNASeq-derived transcriptome comparisons reveal neuromodulatory deficiency in the CO₂ insensitive brown Norway rat. (Puissant MM, Echert AE, Yang C, Mouradian GC Jr, Novotny T, Liu P, Liang M, Hodges MR) J Physiol 2015 01 15;593(2):415-30 PMID: 25630262 PMCID: PMC4303386 01/30/2015       8 Citations
  • Maternal diet during gestation and lactation modifies the severity of salt-induced hypertension and renal injury in Dahl salt-sensitive rats. (Geurts AM, Mattson DL, Liu P, Cabacungan E, Skelton MM, Kurth TM, Yang C, Endres BT, Klotz J, Liang M, Cowley AW Jr) Hypertension 2015 Feb;65(2):447-55 PMID: 25452472 PMCID: PMC4289102 12/03/2014       22 Citations
  • Characteristics of long non-coding RNAs in the Brown Norway rat and alterations in the Dahl salt-sensitive rat. (Wang F, Li L, Xu H, Liu Y, Yang C, Cowley AW Jr, Wang N, Liu P, Liang M) Sci Rep 2014 Nov 21;4:7146 PMID: 25413633 PMCID: PMC4894415 11/22/2014       21 Citations
  • Improved rat genome gene prediction by integration of ESTs with RNA-Seq information. (Li L, Chen E, Yang C, Zhu J, Jayaraman P, De Pons J, Kaczorowski CC, Jacob HJ, Greene AS, Hodges MR, Cowley AW Jr, Liang M, Xu H, Liu P, Lu Y) Bioinformatics 2015 Jan 01;31(1):25-32 PMID: 25217576 PMCID: PMC4296142 09/14/2014       2 Citations
  • Prostate cancer risk locus at 8q24 as a regulatory hub by physical interactions with multiple genomic loci across the genome. (Du M, Yuan T, Schilter KF, Dittmar RL, Mackinnon A, Huang X, Tschannen M, Worthey E, Jacob H, Xia S, Gao J, Tillmans L, Lu Y, Liu P, Thibodeau SN, Wang L) Hum Mol Genet 2015 Jan 01;24(1):154-66 PMID: 25149474 PMCID: PMC4262497 08/26/2014       23 Citations
  • A phase Ib study of the effects of black raspberries on rectal polyps in patients with familial adenomatous polyposis. (Wang LS, Burke CA, Hasson H, Kuo CT, Molmenti CL, Seguin C, Liu P, Huang TH, Frankel WL, Stoner GD) Cancer Prev Res (Phila) 2014 Jul;7(7):666-74 PMID: 24764585 04/26/2014       38 Citations
  • Characterization of biological pathways associated with a 1.37 Mbp genomic region protective of hypertension in Dahl S rats. (Cowley AW Jr, Moreno C, Jacob HJ, Peterson CB, Stingo FC, Ahn KW, Liu P, Vannucci M, Laud PW, Reddy P, Lazar J, Evans L, Yang C, Kurth T, Liang M) Physiol Genomics 2014 Jun 01;46(11):398-410 PMID: 24714719 PMCID: PMC4042181 04/10/2014       9 Citations
  • Identification of the transforming STRN-ALK fusion as a potential therapeutic target in the aggressive forms of thyroid cancer. (Kelly LM, Barila G, Liu P, Evdokimova VN, Trivedi S, Panebianco F, Gandhi M, Carty SE, Hodak SP, Luo J, Dacic S, Yu YP, Nikiforova MN, Ferris RL, Altschuler DL, Nikiforov YE) Proc Natl Acad Sci U S A 2014 Mar 18;111(11):4233-8 PMID: 24613930 PMCID: PMC3964116 03/13/2014       92 Citations
  • Cancer genomics: new software tools making sequencing more accessible. (Chen EG, Liu P, Lu Y) Per Med 2014 Mar;11(2):127-130 PMID: 29751375 03/01/2014    
  • Whole-genome sequencing identifies genomic heterogeneity at a nucleotide and chromosomal level in bladder cancer. (Morrison CD, Liu P, Woloszynska-Read A, Zhang J, Luo W, Qin M, Bshara W, Conroy JM, Sabatini L, Vedell P, Xiong D, Liu S, Wang J, Shen H, Li Y, Omilian AR, Hill A, Head K, Guru K, Kunnev D, Leach R, Eng KH, Darlak C, Hoeflich C, Veeranki S, Glenn S, You M, Pruitt SC, Johnson CS, Trump DL) Proc Natl Acad Sci U S A 2014 Feb 11;111(6):E672-81 PMID: 24469795 PMCID: PMC3926024 01/29/2014       56 Citations
  • Base-resolution maps of 5-methylcytosine and 5-hydroxymethylcytosine in Dahl S rats: effect of salt and genomic sequence. (Liu Y, Liu P, Yang C, Cowley AW Jr, Liang M) Hypertension 2014 Apr;63(4):827-38 PMID: 24420542 PMCID: PMC4315612 01/15/2014       31 Citations
  • ETV6-NTRK3 is a common chromosomal rearrangement in radiation-associated thyroid cancer. (Leeman-Neill RJ, Kelly LM, Liu P, Brenner AV, Little MP, Bogdanova TI, Evdokimova VN, Hatch M, Zurnadzy LY, Nikiforova MN, Yue NJ, Zhang M, Mabuchi K, Tronko MD, Nikiforov YE) Cancer 2014 Mar 15;120(6):799-807 PMID: 24327398 PMCID: PMC3947712 12/12/2013       93 Citations
  • EYA4 is inactivated biallelically at a high frequency in sporadic lung cancer and is associated with familial lung cancer risk. (Wilson IM, Vucic EA, Enfield KS, Thu KL, Zhang YA, Chari R, Lockwood WW, Radulovich N, Starczynowski DT, Banáth JP, Zhang M, Pusic A, Fuller M, Lonergan KM, Rowbotham D, Yee J, English JC, Buys TP, Selamat SA, Laird-Offringa IA, Liu P, Anderson M, You M, Tsao MS, Brown CJ, Bennewith KL, MacAulay CE, Karsan A, Gazdar AF, Lam S, Lam WL) Oncogene 2014 Sep 04;33(36):4464-73 PMID: 24096489 PMCID: PMC4527534 10/08/2013       14 Citations
  • Characteristics of microRNAs enriched in specific cell types and primary tissue types in solid organs. (Kriegel AJ, Liu Y, Liu P, Baker MA, Hodges MR, Hua X, Liang M) Physiol Genomics 2013 Dec 01;45(23):1144-56 PMID: 24085797 PMCID: PMC3882707 10/03/2013       14 Citations
  • Concordant effects of aromatase inhibitors on gene expression in ER+ Rat and human mammary cancers and modulation of the proteins coded by these genes. (Lu Y, You M, Ghazoui Z, Liu P, Vedell PT, Wen W, Bode AM, Grubbs CJ, Lubet RA) Cancer Prev Res (Phila) 2013 Nov;6(11):1151-61 PMID: 24067424 PMCID: PMC3874590 09/27/2013       6 Citations
  • Targeting the endothelial progenitor cell surface proteome to identify novel mechanisms that mediate angiogenic efficacy in a rodent model of vascular disease. (Kaczorowski CC, Stodola TJ, Hoffmann BR, Prisco AR, Liu PY, Didier DN, Karcher JR, Liang M, Jacob HJ, Greene AS) Physiol Genomics 2013 Nov 01;45(21):999-1011 PMID: 24022221 PMCID: PMC3841789 09/12/2013       11 Citations
  • DrGaP: a powerful tool for identifying driver genes and pathways in cancer sequencing studies. (Hua X, Xu H, Yang Y, Zhu J, Liu P, Lu Y) Am J Hum Genet 2013 Sep 05;93(3):439-51 PMID: 23954162 PMCID: PMC3769934 08/21/2013       28 Citations
  • Functional genomic assessment of phosgene-induced acute lung injury in mice. (Leikauf GD, Concel VJ, Bein K, Liu P, Berndt A, Martin TM, Ganguly K, Jang AS, Brant KA, Dopico RA Jr, Upadhyay S, Cario C, Di YP, Vuga LJ, Kostem E, Eskin E, You M, Kaminski N, Prows DR, Knoell DL, Fabisiak JP) Am J Respir Cell Mol Biol 2013 Sep;49(3):368-83 PMID: 23590305 PMCID: PMC3824050 04/18/2013       12 Citations
  • Increased proliferative cells in the medullary thick ascending limb of the loop of Henle in the Dahl salt-sensitive rat. (Yang C, Stingo FC, Ahn KW, Liu P, Vannucci M, Laud PW, Skelton M, O'Connor P, Kurth T, Ryan RP, Moreno C, Tsaih SW, Patone G, Hummel O, Jacob HJ, Liang M, Cowley AW Jr) Hypertension 2013 Jan;61(1):208-15 PMID: 23184381 PMCID: PMC3760736 11/28/2012       15 Citations
  • WNT1-inducible signaling pathway protein 1 contributes to ventilator-induced lung injury. (Li HH, Li Q, Liu P, Liu Y, Li J, Wasserloos K, Chao W, You M, Oury TD, Chhinder S, Hackam DJ, Billiar TR, Leikauf GD, Pitt BR, Zhang LM) Am J Respir Cell Mol Biol 2012 Oct;47(4):528-35 PMID: 22700866 PMCID: PMC3488625 06/16/2012       20 Citations
  • Exome sequencing identifies MXRA5 as a novel cancer gene frequently mutated in non-small cell lung carcinoma from Chinese patients. (Xiong D, Li G, Li K, Xu Q, Pan Z, Ding F, Vedell P, Liu P, Cui P, Hua X, Jiang H, Yin Y, Zhu Z, Li X, Zhang B, Ma D, Wang Y, You M) Carcinogenesis 2012 Sep;33(9):1797-805 PMID: 22696596 PMCID: PMC3514907 06/15/2012       27 Citations
  • Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing. (Liu P, Morrison C, Wang L, Xiong D, Vedell P, Cui P, Hua X, Ding F, Lu Y, James M, Ebben JD, Xu H, Adjei AA, Head K, Andrae JW, Tschannen MR, Jacob H, Pan J, Zhang Q, Van den Bergh F, Xiao H, Lo KC, Patel J, Richmond T, Watt MA, Albert T, Selzer R, Anderson M, Wang J, Wang Y, Starnes S, Yang P, You M) Carcinogenesis 2012 Jul;33(7):1270-6 PMID: 22510280 PMCID: PMC3499051 04/19/2012       111 Citations
  • Integrative assessment of chlorine-induced acute lung injury in mice. (Leikauf GD, Pope-Varsalona H, Concel VJ, Liu P, Bein K, Berndt A, Martin TM, Ganguly K, Jang AS, Brant KA, Dopico RA Jr, Upadhyay S, Di YP, Li Q, Hu Z, Vuga LJ, Medvedovic M, Kaminski N, You M, Alexander DC, McDunn JE, Prows DR, Knoell DL, Fabisiak JP) Am J Respir Cell Mol Biol 2012 Aug;47(2):234-44 PMID: 22447970 PMCID: PMC3423464 03/27/2012       18 Citations
  • MicroRNA profiling and prediction of recurrence/relapse-free survival in stage I lung cancer. (Lu Y, Govindan R, Wang L, Liu PY, Goodgame B, Wen W, Sezhiyan A, Pfeifer J, Li YF, Hua X, Wang Y, Yang P, You M) Carcinogenesis 2012 May;33(5):1046-54 PMID: 22331473 PMCID: PMC3334512 02/15/2012       98 Citations
  • Gene-expression signature predicts postoperative recurrence in stage I non-small cell lung cancer patients. (Lu Y, Wang L, Liu P, Yang P, You M) PLoS One 2012;7(1):e30880 PMID: 22292069 PMCID: PMC3264655 02/01/2012       22 Citations
  • Genome-wide association and fine mapping of genetic loci predisposing to colon carcinogenesis in mice. (Liu P, Lu Y, Liu H, Wen W, Jia D, Wang Y, You M) Mol Cancer Res 2012 Jan;10(1):66-74 PMID: 22127497 12/01/2011       17 Citations
  • Neutrophils are required for 3-methylcholanthrene-initiated, butylated hydroxytoluene-promoted lung carcinogenesis. (Vikis HG, Gelman AE, Franklin A, Stein L, Rymaszewski A, Zhu J, Liu P, Tichelaar JW, Krupnick AS, You M) Mol Carcinog 2012 Dec;51(12):993-1002 PMID: 22006501 PMCID: PMC3389580 10/19/2011       11 Citations
  • Modulation of gene expression and cell-cycle signaling pathways by the EGFR inhibitor gefitinib (Iressa) in rat urinary bladder cancer. (Lu Y, Liu P, Van den Bergh F, Zellmer V, James M, Wen W, Grubbs CJ, Lubet RA, You M) Cancer Prev Res (Phila) 2012 Feb;5(2):248-59 PMID: 21982874 10/11/2011       12 Citations
  • Principles for the post-GWAS functional characterization of cancer risk loci. (Freedman ML, Monteiro AN, Gayther SA, Coetzee GA, Risch A, Plass C, Casey G, De Biasi M, Carlson C, Duggan D, James M, Liu P, Tichelaar JW, Vikis HG, You M, Mills IG) Nat Genet 2011 Jun;43(6):513-8 PMID: 21614091 PMCID: PMC3325768 05/27/2011       250 Citations
  • Haplotype association mapping of acute lung injury in mice implicates activin a receptor, type 1. (Leikauf GD, Concel VJ, Liu P, Bein K, Berndt A, Ganguly K, Jang AS, Brant KA, Dietsch M, Pope-Varsalona H, Dopico RA Jr, Di YP, Li Q, Vuga LJ, Medvedovic M, Kaminski N, You M, Prows DR) Am J Respir Crit Care Med 2011 Jun 01;183(11):1499-509 PMID: 21297076 PMCID: PMC3137140 02/08/2011       28 Citations
  • Aerosolized bexarotene inhibits lung tumorigenesis without increasing plasma triglyceride and cholesterol levels in mice. (Zhang Q, Pan J, Zhang J, Liu P, Chen R, Chen DR, Lubet R, Wang Y, You M) Cancer Prev Res (Phila) 2011 Feb;4(2):270-6 PMID: 21163938 12/18/2010       15 Citations
  • Cross-species comparison of orthologous gene expression in human bladder cancer and carcinogen-induced rodent models. (Lu Y, Liu P, Wen W, Grubbs CJ, Townsend RR, Malone JP, Lubet RA, You M) Am J Transl Res 2010 Sep 20;3(1):8-27 PMID: 21139803 PMCID: PMC2981423 12/09/2010    
  • Functional genomics of chlorine-induced acute lung injury in mice. (Leikauf GD, Pope-Varsalona H, Concel VJ, Liu P, Bein K, Brant KA, Dopico RA, Di YP, Jang AS, Dietsch M, Medvedovic M, Li Q, Vuga LJ, Kaminski N, You M, Prows DR) Proc Am Thorac Soc 2010 Jul;7(4):294-6 PMID: 20601635 PMCID: PMC3136967 07/06/2010       7 Citations
  • A second genetic variant on chromosome 15q24-25.1 associates with lung cancer. (Liu P, Yang P, Wu X, Vikis HG, Lu Y, Wang Y, Schwartz AG, Pinney SM, de Andrade M, Gazdar A, Gaba C, Mandal D, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Spitz M, Amos CI, Anderson MW, You M) Cancer Res 2010 Apr 15;70(8):3128-35 PMID: 20395203 PMCID: PMC3378320 04/17/2010       3 Citations
  • Cumulative effect of multiple loci on genetic susceptibility to familial lung cancer. (Liu P, Vikis HG, Lu Y, Wang Y, Schwartz AG, Pinney SM, Yang P, de Andrade M, Gazdar A, Gaba C, Mandal D, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Amos CI, Anderson MW, You M) Cancer Epidemiol Biomarkers Prev 2010 Feb;19(2):517-24 PMID: 20142248 PMCID: PMC2846747 02/10/2010       24 Citations
  • Genetic variants cis-regulating Xrn2 expression contribute to the risk of spontaneous lung tumor. (Lu Y, Liu P, James M, Vikis HG, Liu H, Wen W, Franklin A, You M) Oncogene 2010 Feb 18;29(7):1041-9 PMID: 19915612 PMCID: PMC6019621 11/17/2009       13 Citations
  • Haplotype and cell proliferation analyses of candidate lung cancer susceptibility genes on chromosome 15q24-25.1. (Liu Y, Liu P, Wen W, James MA, Wang Y, Bailey-Wilson JE, Amos CI, Pinney SM, Yang P, de Andrade M, Petersen GM, Wiest JS, Fain PR, Schwartz AG, Gazdar A, Gaba C, Rothschild H, Mandal D, Kupert E, Lee J, Seminara D, Minna J, Anderson MW, You M) Cancer Res 2009 Oct 01;69(19):7844-50 PMID: 19789337 PMCID: PMC2846106 10/01/2009       34 Citations
  • Identification of Las2, a major modifier gene affecting the Pas1 mouse lung tumor susceptibility locus. (Liu PY, Vikis H, James M, Lu Y, Wang DL, Liu HB, Wen WD, Wang Y, You M) Cancer Res 2009 Aug 01;69(15):6290-8 PMID: 19622765 07/23/2009       6 Citations
  • Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5. (Wang JC, Cruchaga C, Saccone NL, Bertelsen S, Liu P, Budde JP, Duan W, Fox L, Grucza RA, Kern J, Mayo K, Reyes O, Rice J, Saccone SF, Spiegel N, Steinbach JH, Stitzel JA, Anderson MW, You M, Stevens VL, Bierut LJ, Goate AM, COGEND collaborators and GELCC collaborators) Hum Mol Genet 2009 Aug 15;18(16):3125-35 PMID: 19443489 PMCID: PMC2714722 05/16/2009       126 Citations
  • Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 as a likely candidate gene. (You M, Wang D, Liu P, Vikis H, James M, Lu Y, Wang Y, Wang M, Chen Q, Jia D, Liu Y, Wen W, Yang P, Sun Z, Pinney SM, Zheng W, Shu XO, Long J, Gao YT, Xiang YB, Chow WH, Rothman N, Petersen GM, de Andrade M, Wu Y, Cunningham JM, Wiest JS, Fain PR, Schwartz AG, Girard L, Gazdar A, Gaba C, Rothschild H, Mandal D, Coons T, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Amos CI, Anderson MW) Clin Cancer Res 2009 Apr 15;15(8):2666-74 PMID: 19351763 PMCID: PMC2746091 04/09/2009       56 Citations
  • Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer. (Liu P, Vikis HG, Wang D, Lu Y, Wang Y, Schwartz AG, Pinney SM, Yang P, de Andrade M, Petersen GM, Wiest JS, Fain PR, Gazdar A, Gaba C, Rothschild H, Mandal D, Coons T, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Wu X, Spitz MR, Eisen T, Houlston RS, Amos CI, Anderson MW, You M) J Natl Cancer Inst 2008 Sep 17;100(18):1326-30 PMID: 18780872 PMCID: PMC2538550 09/11/2008       107 Citations
  • Common human cancer genes discovered by integrated gene-expression analysis. (Lu Y, Yi Y, Liu P, Wen W, James M, Wang D, You M) PLoS One 2007 Nov 07;2(11):e1149 PMID: 17989776 PMCID: PMC2065803 11/09/2007       56 Citations
  • Large-scale in silico mapping of complex quantitative traits in inbred mice. (Liu P, Vikis H, Lu Y, Wang D, You M) PLoS One 2007 Jul 25;2(7):e651 PMID: 17653278 PMCID: PMC1920557 07/27/2007       31 Citations
  • A gene expression signature predicts survival of patients with stage I non-small cell lung cancer. (Lu Y, Lemon W, Liu PY, Yi Y, Morrison C, Yang P, Sun Z, Szoke J, Gerald WL, Watson M, Govindan R, You M) PLoS Med 2006 Dec;3(12):e467 PMID: 17194181 PMCID: PMC1716187 12/30/2006       211 Citations
  • Candidate lung tumor susceptibility genes identified through whole-genome association analyses in inbred mice. (Liu P, Wang Y, Vikis H, Maciag A, Wang D, Lu Y, Liu Y, You M) Nat Genet 2006 Aug;38(8):888-95 PMID: 16862160 07/25/2006       65 Citations
  • Accurate haplotype inference for multiple linked single-nucleotide polymorphisms using sibship data. (Liu PY, Lu Y, Deng HW) Genetics 2006 Sep;174(1):499-509 PMID: 16783022 PMCID: PMC1569787 06/20/2006       7 Citations
  • Impacts of QTL x environment interactions on genetic response to marker-assisted selection. (Liu PY, Zhu J, Yan L) Yi Chuan Xue Bao 2006 Jan;33(1):63-71 PMID: 16450589 02/03/2006       6 Citations
  • Improvement of mapping accuracy by unifying linkage and association analysis. (Lou XY, Ma JZ, Yang MC, Zhu J, Liu PY, Deng HW, Elston RC, Li MD) Genetics 2006 Jan;172(1):647-61 PMID: 16172505 PMCID: PMC1456190 09/21/2005       5 Citations
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  • Last update: 11/27/2018
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