Medical College of Wisconsin
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Rebekah L. Gundry PhD

Rebekah L. Gundry PhD

Associate Professor

Institution: Medical College of Wisconsin
Department: Biochemistry

Member of the Cancer Center
Member of the Cardiovascular Center


Research Experience

  • Biomarkers, Pharmacological
  • Embryology
  • Fetal Heart
  • Flow Cytometry
  • Heart Failure
  • Immunophenotyping
  • Mass Spectrometry
  • Membrane Glycoproteins
  • Membrane Proteins
  • Myocytes, Cardiac
  • NAD
  • Nicotinamide Phosphoribosyltransferase
  • Pluripotent Stem Cells
  • Proteomics
  • Regenerative Medicine
  • Stem Cells
  • Methodologies and Techniques

  • Flow Cytometry
  • Immunohistochemistry
  • Immunoprecipitation
  • In Situ Hybridization
  • Mass Spectrometry
  • Microscopy, Confocal
  • Microscopy, Fluorescence
  • Pluripotent Stem Cells
  • Proteomics
  • Tandem Mass Spectrometry
  • Publications

  • Quantitative Top-Down Mass Spectrometry Identifies Proteoforms Differentially Released during Mechanical Stimulation of Mouse Skin. (Moehring F, Waas M, Keppel TR, Rathore D, Cowie AM, Stucky CL, Gundry RL) J Proteome Res 2018 Aug 03;17(8):2635-2648 PMID: 29925238 PMCID: PMC6195672 06/22/2018    
  • Mass Spectrometry-Based Identification of Extracellular Domains of Cell Surface N-Glycoproteins: Defining the Accessible Surfaceome for Immunophenotyping Stem Cells and Their Derivatives. (Fujinaka CM, Waas M, Gundry RL) Methods Mol Biol 2018;1722:57-78 PMID: 29264798 PMCID: PMC5791894 12/22/2017    
  • Cell Surface Proteomics of N-Linked Glycoproteins for Typing of Human Lymphocytes. (Haverland NA, Waas M, Ntai I, Keppel T, Gundry RL, Kelleher NL) Proteomics 2017 Oct;17(19) PMID: 28834292 PMCID: PMC5633517 08/24/2017       1 Citations
  • Cardiomyocyte Differentiation Promotes Cell Survival During Nicotinamide Phosphoribosyltransferase Inhibition Through Increased Maintenance of Cellular Energy Stores. (Kropp EM, Broniowska KA, Waas M, Nycz A, Corbett JA, Gundry RL) Stem Cells Transl Med 2017 Apr;6(4):1191-1201 PMID: 28224719 PMCID: PMC5442850 02/23/2017    
  • Concise Review: Cell Surface N-Linked Glycoproteins as Potential Stem Cell Markers and Drug Targets. (Boheler KR, Gundry RL) Stem Cells Transl Med 2017 Jan;6(1):131-138 PMID: 28170199 PMCID: PMC5442750 02/09/2017    
  • N-glycoprotein surfaceome of human induced pluripotent stem cell derived hepatic endoderm. (Mallanna SK, Waas M, Duncan SA, Gundry RL) Proteomics 2017 03;17(5) PMID: 27966262 PMCID: PMC5340625 12/15/2016       3 Citations
  • Mapping the Cell-Surface N-Glycoproteome of Human Hepatocytes Reveals Markers for Selecting a Homogeneous Population of iPSC-Derived Hepatocytes. (Mallanna SK, Cayo MA, Twaroski K, Gundry RL, Duncan SA) Stem Cell Reports 2016 09 13;7(3):543-556 PMID: 27569060 PMCID: PMC5032032 08/30/2016       13 Citations
  • A mass spectrometric-derived cell surface protein atlas. (Bausch-Fluck D, Hofmann A, Bock T, Frei AP, Cerciello F, Jacobs A, Moest H, Omasits U, Gundry RL, Yoon C, Schiess R, Schmidt A, Mirkowska P, Härtlová A, Van Eyk JE, Bourquin JP, Aebersold R, Boheler KR, Zandstra P, Wollscheid B) PLoS One 2015;10(3):e0121314 PMID: 25894527 PMCID: PMC4404347 04/22/2015       56 Citations
  • Bacterial expression of the phosphodiester-binding site of the cation-independent mannose 6-phosphate receptor for crystallographic and NMR studies. (Olson LJ, Jensen DR, Volkman BF, Kim JJ, Peterson FC, Gundry RL, Dahms NM) Protein Expr Purif 2015 Jul;111:91-7 PMID: 25863146 PMCID: PMC4417374 04/12/2015    
  • Inhibition of an NAD⁺ salvage pathway provides efficient and selective toxicity to human pluripotent stem cells. (Kropp EM, Oleson BJ, Broniowska KA, Bhattacharya S, Chadwick AC, Diers AR, Hu Q, Sahoo D, Hogg N, Boheler KR, Corbett JA, Gundry RL) Stem Cells Transl Med 2015 May;4(5):483-93 PMID: 25834119 PMCID: PMC4414215 04/03/2015       8 Citations
  • Activin-A and Bmp4 levels modulate cell type specification during CHIR-induced cardiomyogenesis. (Kim MS, Horst A, Blinka S, Stamm K, Mahnke D, Schuman J, Gundry R, Tomita-Mitchell A, Lough J) PLoS One 2015;10(2):e0118670 PMID: 25706534 PMCID: PMC4338295 02/24/2015       7 Citations
  • Structure-function analysis of CCL28 in the development of post-viral asthma. (Thomas MA, Buelow BJ, Nevins AM, Jones SE, Peterson FC, Gundry RL, Grayson MH, Volkman BF) J Biol Chem 2015 Feb 13;290(7):4528-36 PMID: 25556652 PMCID: PMC4326855 01/06/2015       7 Citations
  • Hold or fold--proteins in advanced heart failure and myocardial recovery. (Mahr C, Gundry RL) Proteomics Clin Appl 2015 Feb;9(1-2):121-33 PMID: 25331159 PMCID: PMC4412349 10/22/2014       1 Citations
  • High efficiency differentiation of human pluripotent stem cells to cardiomyocytes and characterization by flow cytometry. (Bhattacharya S, Burridge PW, Kropp EM, Chuppa SL, Kwok WM, Wu JC, Boheler KR, Gundry RL) J Vis Exp 2014 Sep 23(91):52010 PMID: 25286293 PMCID: PMC4448667 10/07/2014       24 Citations
  • A human pluripotent stem cell surface N-glycoproteome resource reveals markers, extracellular epitopes, and drug targets. (Boheler KR, Bhattacharya S, Kropp EM, Chuppa S, Riordon DR, Bausch-Fluck D, Burridge PW, Wu JC, Wersto RP, Chan GC, Rao S, Wollscheid B, Gundry RL) Stem Cell Reports 2014 Jul 08;3(1):185-203 PMID: 25068131 PMCID: PMC4110789 07/30/2014       44 Citations
  • N-glycoprotein surfaceomes of four developmentally distinct mouse cell types. (Kropp EM, Bhattacharya S, Waas M, Chuppa SL, Hadjantonakis AK, Boheler KR, Gundry RL) Proteomics Clin Appl 2014 Aug;8(7-8):603-9 PMID: 24920426 PMCID: PMC4151168 06/13/2014       7 Citations
  • Combine and conquer: surfactants, solvents, and chaotropes for robust mass spectrometry based analyses of membrane proteins. (Waas M, Bhattacharya S, Chuppa S, Wu X, Jensen DR, Omasits U, Wollscheid B, Volkman BF, Noon KR, Gundry RL) Anal Chem 2014 Feb 04;86(3):1551-9 PMID: 24392666 PMCID: PMC4007983 01/08/2014       19 Citations
  • A cell surfaceome map for immunophenotyping and sorting pluripotent stem cells. (Gundry RL, Riordon DR, Tarasova Y, Chuppa S, Bhattacharya S, Juhasz O, Wiedemeier O, Milanovich S, Noto FK, Tchernyshyov I, Raginski K, Bausch-Fluck D, Tae HJ, Marshall S, Duncan SA, Wollscheid B, Wersto RP, Rao S, Van Eyk JE, Boheler KR) Mol Cell Proteomics 2012 Aug;11(8):303-16 PMID: 22493178 PMCID: PMC3412963 04/12/2012       31 Citations
  • Human ESC/iPSC-based "Omics" and Bioinformatics for Translational Research. (Müller G, Tarasov KV, Gundry RL, Boheler KR) Drug Discov Today Dis Models 2012;9(4):e161-e170 PMID: 23682293 PMCID: PMC3653319 01/01/2012    
  • Embryonic stem cell-derived cardiomyocyte heterogeneity and the isolation of immature and committed cells for cardiac remodeling and regeneration. (Boheler KR, Joodi RN, Qiao H, Juhasz O, Urick AL, Chuppa SL, Gundry RL, Wersto RP, Zhou R) Stem Cells Int 2011;2011:214203 PMID: 21912557 PMCID: PMC3168772 09/14/2011    
  • Pluripotent stem cell heterogeneity and the evolving role of proteomic technologies in stem cell biology. (Gundry RL, Burridge PW, Boheler KR) Proteomics 2011 Oct;11(20):3947-61 PMID: 21834136 PMCID: PMC3311164 08/13/2011       13 Citations
  • Expanding the mouse embryonic stem cell proteome: combining three proteomic approaches. (Gundry RL, Tchernyshyov I, Sheng S, Tarasova Y, Raginski K, Boheler KR, Van Eyk JE) Proteomics 2010 Jul;10(14):2728-32 PMID: 20512790 PMCID: PMC2934747 06/01/2010       14 Citations
  • Preparation of proteins and peptides for mass spectrometry analysis in a bottom-up proteomics workflow. (Gundry RL, White MY, Murray CI, Kane LA, Fu Q, Stanley BA, Van Eyk JE) Curr Protoc Mol Biol 2009 Oct;Chapter 10:Unit10.25 PMID: 19816929 PMCID: PMC2905857 10/10/2009       85 Citations
  • The mouse C2C12 myoblast cell surface N-linked glycoproteome: identification, glycosite occupancy, and membrane orientation. (Gundry RL, Raginski K, Tarasova Y, Tchernyshyov I, Bausch-Fluck D, Elliott ST, Boheler KR, Van Eyk JE, Wollscheid B) Mol Cell Proteomics 2009 Nov;8(11):2555-69 PMID: 19656770 PMCID: PMC2773721 08/07/2009       55 Citations
  • A novel role for proteomics in the discovery of cell-surface markers on stem cells: Scratching the surface. (Gundry RL, Boheler KR, Van Eyk JE, Wollscheid B) Proteomics Clin Appl 2008 Jun 12;2(6):892-903 PMID: 19526049 PMCID: PMC2633130 06/16/2009    
  • Assessment of albumin removal from an immunoaffinity spin column: critical implications for proteomic examination of the albuminome and albumin-depleted samples. (Gundry RL, White MY, Nogee J, Tchernyshyov I, Van Eyk JE) Proteomics 2009 Apr;9(7):2021-8 PMID: 19294703 PMCID: PMC3683576 03/19/2009       50 Citations
  • Nitrosative stress with HIV dementia causes decreased L-prostaglandin D synthase activity. (Li W, Malpica-Llanos TM, Gundry R, Cotter RJ, Sacktor N, McArthur J, Nath A) Neurology 2008 May 06;70(19 Pt 2):1753-62 PMID: 18077799 12/14/2007       25 Citations
  • Unraveling the complexity of circulating forms of brain natriuretic peptide. (Gundry RL, Van Eyk JE) Clin Chem 2007 Jul;53(7):1181-2 PMID: 17582147 06/22/2007       9 Citations
  • Mitochondrial DNA analysis of the domestic dog: control region variation within and among breeds. (Gundry RL, Allard MW, Moretti TR, Honeycutt RL, Wilson MR, Monson KL, Foran DR) J Forensic Sci 2007 May;52(3):562-72 PMID: 17456083 04/26/2007       46 Citations
  • Investigation of an albumin-enriched fraction of human serum and its albuminome. (Gundry RL, Fu Q, Jelinek CA, Van Eyk JE, Cotter RJ) Proteomics Clin Appl 2007 Jan 01;1(1):73-88 PMID: 20204147 PMCID: PMC2831644 01/01/2007    
  • When does a fingerprint constitute a diagnostic? (White MY, Gundry RL, Cordwell SJ) Lancet 2006 Sep 16;368(9540):971-3 PMID: 16980095 09/19/2006       10 Citations
  • Cleavage of cystatin C in the cerebrospinal fluid of patients with multiple sclerosis. (Irani DN, Anderson C, Gundry R, Cotter R, Moore S, Kerr DA, McArthur JC, Sacktor N, Pardo CA, Jones M, Calabresi PA, Nath A) Ann Neurol 2006 Feb;59(2):237-47 PMID: 16437581 01/27/2006       85 Citations
  • Disposable hydrophobic surface on MALDI targets for enhancing MS and MS/MS data of peptides. (Gundry RL, Edward R, Kole TP, Sutton C, Cotter RJ) Anal Chem 2005 Oct 15;77(20):6609-17 PMID: 16223247 10/15/2005       18 Citations
  • Tandem Time-of-Flight (TOF/TOF) Mass Spectrometry and Proteomics. (Cotter RJ, Iltchenko S, Wang D, Gundry R) J Mass Spectrom Soc Jpn 2005 Jan 05;53(1):7-17 PMID: 20717501 PMCID: PMC2922030 01/05/2005    
  • Heart disease, clinical proteomics and mass spectrometry. (Stanley BA, Gundry RL, Cotter RJ, Van Eyk JE) Dis Markers 2004;20(3):167-78 PMID: 15502250 PMCID: PMC3839266 10/27/2004       62 Citations
  • 4-Aminopiperidine-4-carboxylic Acid: A Cyclic alpha,alpha-Disubstituted Amino Acid for Preparation of Water-Soluble Highly Helical Peptides. (Wysong CL, Yokum TS, Morales GA, Gundry RL, McLaughlin ML, Hammer RP) J Org Chem 1996 Nov 01;61(22):7650-7651 PMID: 11667711 11/01/1996    
  • Last update: 07/11/2018
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