Medical College of Wisconsin
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Rodney E. Willoughby MD


Institution: Medical College of Wisconsin
Department: Pediatrics
Division: Infectious Disease

Member of the Cardiovascular Center


  • Successful Application of Whole Genome Sequencing in a Medical Genetics Clinic. (Bick D, Fraser PC, Gutzeit MF, Harris JM, Hambuch TM, Helbling DC, Jacob HJ, Kersten JN, Leuthner SR, May T, North PE, Prisco SZ, Schuler BA, Shimoyama M, Strong KA, Van Why SK, Veith R, Verbsky J, Weborg AM Jr, Wilk BM, Willoughby RE Jr, Worthey EA, Dimmock DP) J Pediatr Genet 2017 Jun;6(2):61-76 PMID: 28496993 PMCID: PMC5423809 05/13/2017    
  • Implementation of American Academy of Pediatrics guidelines for palivizumab prophylaxis in a pediatric hospital. (Zembles TN, Gaertner KM, Gutzeit MF, Willoughby RE) Am J Health Syst Pharm 2016 Mar 15;73(6):405-8 PMID: 26953285 03/10/2016       3 Citations
  • Rabies: Rare Human Infection - Common Questions. (Willoughby RE Jr) Infect Dis Clin North Am 2015 Dec;29(4):637-50 PMID: 26384549 09/20/2015       7 Citations
  • A Case of Necrotizing Epiglottitis Due to Nontoxigenic Corynebacterium diphtheriae. (Lake JA, Ehrhardt MJ, Suchi M, Chun RH, Willoughby RE) Pediatrics 2015 Jul;136(1):e242-5 PMID: 26055849 06/10/2015       6 Citations
  • Clinical guidance for smallpox vaccine use in a postevent vaccination program. (Petersen BW, Damon IK, Pertowski CA, Meaney-Delman D, Guarnizo JT, Beigi RH, Edwards KM, Fisher MC, Frey SE, Lynfield R, Willoughby RE) MMWR Recomm Rep 2015 Feb 20;64(RR-02):1-26 PMID: 25695372 02/20/2015       19 Citations
  • Virology, immunology and pathology of human rabies during treatment. (Caicedo Y, Paez A, Kuzmin I, Niezgoda M, Orciari LA, Yager PA, Recuenco S, Franka R, Velasco-Villa A, Willoughby RE Jr) Pediatr Infect Dis J 2015 May;34(5):520-8 PMID: 25405805 PMCID: PMC4809748 11/19/2014       6 Citations
  • Clostridium difficile infection in infants and children. (Schutze GE, Willoughby RE, Committee on Infectious Diseases, American Academy of Pediatrics) Pediatrics 2013 Jan;131(1):196-200 PMID: 23277317 01/02/2013    
  • Metabolomics of cerebrospinal fluid from humans treated for rabies. (O'Sullivan A, Willoughby RE, Mishchuk D, Alcarraz B, Cabezas-Sanchez C, Condori RE, David D, Encarnacion R, Fatteh N, Fernandez J, Franka R, Hedderwick S, McCaughey C, Ondrush J, Paez-Martinez A, Rupprecht C, Velasco-Villa A, Slupsky CM) J Proteome Res 2013 Jan 04;12(1):481-90 PMID: 23163834 PMCID: PMC4824192 11/21/2012       27 Citations
  • Presumed hydrogen sulfide-mediated neurotoxicity after streptococcus anginosus group meningitis. (Verma S, Landisch R, Quirk B, Schmainda K, Prah M, Whelan HT, Willoughby RE Jr) Pediatr Infect Dis J 2013 Feb;32(2):189-91 PMID: 23014355 PMCID: PMC3548939 09/28/2012       2 Citations
  • Resistance to rabies. (Willoughby RE) Am J Trop Med Hyg 2012 Aug;87(2):205 PMID: 22855748 PMCID: PMC3414553 08/03/2012    
  • H1N1 hemagglutinin-inhibition seroprevalence in Emergency Department Health Care workers after the first wave of the 2009 influenza pandemic. (Kumar S, Fan J, Melzer-Lange M, Trost J, Havens PL, Willoughby RE, Chusid MJ, Henrickson KJ) Pediatr Emerg Care 2011 Sep;27(9):804-7 PMID: 21878831 09/01/2011       7 Citations
  • Failure of the Milwaukee protocol in a child with rabies. (Aramburo A, Willoughby RE, Bollen AW, Glaser CA, Hsieh CJ, Davis SL, Martin KW, Roy-Burman A) Clin Infect Dis 2011 Sep;53(6):572-4 PMID: 21865193 08/26/2011       22 Citations
  • Epidemiologic Observations from Passive and Targeted Surveillance during the First Wave of the 2009 H1N1 Influenza Pandemic in Milwaukee, WI. (Kumar S, Chusid MJ, Willoughby RE, Havens PL, Kehl SC, Ledeboer NA, Simpson P, Vandyke M, Davis E, Gaffney K, Li SH, Bose ME, Henrickson KJ) Viruses 2010;2(4):782-795 PMID: 20648234 PMCID: PMC2905828 07/22/2010    
  • Clinical and epidemiologic characteristics of children hospitalized with 2009 pandemic H1N1 influenza A infection. (Kumar S, Havens PL, Chusid MJ, Willoughby RE Jr, Simpson P, Henrickson KJ) Pediatr Infect Dis J 2010 Jul;29(7):591-4 PMID: 20589976 07/01/2010       79 Citations
  • Immunovirological correlates in human rabies treated with therapeutic coma. (Hunter M, Johnson N, Hedderwick S, McCaughey C, Lowry K, McConville J, Herron B, McQuaid S, Marston D, Goddard T, Harkess G, Goharriz H, Voller K, Solomon T, Willoughby RE, Fooks AR) J Med Virol 2010 Jul;82(7):1255-65 PMID: 20513093 06/01/2010       39 Citations
  • "Early death" and the contraindication of vaccine during treatment of rabies. (Willoughby RE Jr) Vaccine 2009 Nov 27;27(51):7173-7 PMID: 19925949 11/21/2009       17 Citations
  • Introduction of a Novel Swine-Origin Influenza A (H1N1) Virus into Milwaukee, Wisconsin in 2009. (Kumar S, Chusid MJ, Willoughby RE, Havens PL, Kehl SC, Ledeboer NA, Li SH, Henrickson KJ) Viruses 2009 06 01;1(1):72-83 PMID: 19865496 PMCID: PMC2768288 10/30/2009    
  • Applying the Milwaukee protocol to treat canine rabies in Equatorial Guinea. (Rubin J, David D, Willoughby RE Jr, Rupprecht CE, Garcia C, Guarda DC, Zohar Z, Stamler A) Scand J Infect Dis 2009;41(5):372-5 PMID: 19263274 03/06/2009       29 Citations
  • Tetrahydrobiopterin deficiency in human rabies. (Willoughby RE, Opladen T, Maier T, Rhead W, Schmiedel S, Hoyer J, Drosten C, Rupprecht CE, Hyland K, Hoffmann GF) J Inherit Metab Dis 2009 Feb;32(1):65-72 PMID: 18949578 10/25/2008       23 Citations
  • Generalised cranial artery spasm in human rabies. (Willoughby RE, Roy-Burman A, Martin KW, Christensen JC, Westenkirschner DF, Fleck JD, Glaser C, Hyland K, Rupprecht CE) Dev Biol (Basel) 2008;131:367-75 PMID: 18634498 07/19/2008       17 Citations
  • Long-term follow-up after treatment of rabies by induction of coma. (Hu WT, Willoughby RE Jr, Dhonau H, Mack KJ) N Engl J Med 2007 Aug 30;357(9):945-6 PMID: 17761604 09/01/2007       44 Citations
  • A cure for a rabies? (Willoughby RE Jr) Sci Am 2007 Apr;296(4):88-95 PMID: 17479635 05/08/2007       9 Citations
  • Severe osteomyelitis caused by Myceliophthora thermophila after a pitchfork injury. (Destino L, Sutton DA, Helon AL, Havens PL, Thometz JG, Willoughby RE Jr, Chusid MJ) Ann Clin Microbiol Antimicrob 2006 Sep 08;5:21 PMID: 16961922 PMCID: PMC1592504 09/12/2006       21 Citations
  • Prophylaxis against rabies in children exposed to bats. (Willoughby RE Jr, Hammarin AL) Pediatr Infect Dis J 2005 Dec;24(12):1109-10 PMID: 16371876 12/24/2005       4 Citations
  • Survival after treatment of rabies with induction of coma. (Willoughby RE Jr, Tieves KS, Hoffman GM, Ghanayem NS, Amlie-Lefond CM, Schwabe MJ, Chusid MJ, Rupprecht CE) N Engl J Med 2005 Jun 16;352(24):2508-14 PMID: 15958806 06/17/2005       376 Citations
  • Prevention of necrotizing enterocolitis with probiotics. (Kliegman RM, Willoughby RE) Pediatrics 2005 Jan;115(1):171-2 PMID: 15629995 01/05/2005       26 Citations
  • Beware observational studies in neonatal practice. (Willoughby RE Jr) Arch Pediatr Adolesc Med 2003 Sep;157(9):934-5; author reply 935 PMID: 12963601 09/10/2003    
  • Chorioamnionitis and brain injury. (Willoughby RE Jr, Nelson KB) Clin Perinatol 2002 Dec;29(4):603-21 PMID: 12516738 01/09/2003       73 Citations
  • Intrauterine exposure to infection and risk of cerebral palsy in very preterm infants. (Grether JK, Nelson KB, Walsh E, Willoughby RE, Redline RW) Arch Pediatr Adolesc Med 2003 Jan;157(1):26-32 PMID: 12517191 01/09/2003       73 Citations
  • Maternal infections are depressing. (Willoughby RE Jr) Pediatrics 2002 Oct;110(4):832-3 PMID: 12359803 10/03/2002    
  • Polymorphisms of the cytomegalovirus (CMV)-encoded tumor necrosis factor-alpha and beta-chemokine receptors in congenital CMV disease. (Arav-Boger R, Willoughby RE, Pass RF, Zong JC, Jang WJ, Alcendor D, Hayward GS) J Infect Dis 2002 Oct 15;186(8):1057-64 PMID: 12355354 10/02/2002       89 Citations
  • Pilot study of antibiotic cycling in a pediatric intensive care unit. (Moss WJ, Beers MC, Johnson E, Nichols DG, Perl TM, Dick JD, Veltri MA, Willoughby RE Jr) Crit Care Med 2002 Aug;30(8):1877-82 PMID: 12163809 08/07/2002    
  • Overview: infection during pregnancy and neurologic outcome in the child. (Nelson KB, Willoughby RE) Ment Retard Dev Disabil Res Rev 2002;8(1):1-2 PMID: 11921379 03/29/2002       17 Citations
  • Leukocytosis caused by prostaglandin E1 in neonates. (Arav-Boger R, Baggett HC, Spevak PJ, Willoughby RE) J Pediatr 2001 Feb;138(2):263-5 PMID: 11174627 02/15/2001       10 Citations
  • Infection, inflammation and the risk of cerebral palsy. (Nelson KB, Willoughby RE) Curr Opin Neurol 2000 Apr;13(2):133-9 PMID: 10987569 09/15/2000       126 Citations
  • Colonization by Streptococcus penumoniae in human immunodeficiency virus-infected children. (Polack FP, Flayhart DC, Zahurak ML, Dick JD, Willoughby RE) Pediatr Infect Dis J 2000 Jul;19(7):608-12 PMID: 10917217 08/05/2000       26 Citations
  • Recurrent Francisella philomiragia sepsis in chronic granulomatous disease. (Polack FP, Harrington SM, Winkelstein JA, Merz WG, Willoughby RE) Pediatr Infect Dis J 1998 May;17(5):442-3 PMID: 9613671 06/05/1998       7 Citations
  • Francisella philomiragia sepsis in chronic granulomatous disease. (Sicherer SH, Asturias EJ, Winkelstein JA, Dick JD, Willoughby RE) Pediatr Infect Dis J 1997 Apr;16(4):420-2 PMID: 9109152 04/01/1997       13 Citations
  • Necrotizing enterocolitis and infection. (Willoughby RE Jr, Pickering LK) Clin Perinatol 1994 Jun;21(2):307-15 PMID: 8070228 06/01/1994       20 Citations
  • Rotaviruses preferentially bind O-linked sialylglycoconjugates and sialomucins. (Willoughby RE) Glycobiology 1993 Oct;3(5):437-45 PMID: 8286856 10/01/1993       37 Citations
  • Cell surface ligands for rotavirus: mouse intestinal glycolipids and synthetic carbohydrate analogs. (Srnka CA, Tiemeyer M, Gilbert JH, Moreland M, Schweingruber H, de Lappe BW, James PG, Gant T, Willoughby RE, Yolken RH) Virology 1992 Oct;190(2):794-805 PMID: 1325706 10/01/1992       30 Citations
  • Growth of group A rotaviruses in a human liver cell line. (Schwarz KB, Moore TJ, Willoughby RE Jr, Wee SB, Vonderfecht SL, Yolken RH) Hepatology 1990 Oct;12(4 Pt 1):638-43 PMID: 2170264 10/01/1990       14 Citations
  • Rotaviruses specifically bind to the neutral glycosphingolipid asialo-GM1. (Willoughby RE, Yolken RH, Schnaar RL) J Virol 1990 Oct;64(10):4830-5 PMID: 2168971 PMCID: PMC247971 10/01/1990       48 Citations
  • SA11 rotavirus is specifically inhibited by an acetylated sialic acid. (Willoughby RE, Yolken RH) J Infect Dis 1990 Jan;161(1):116-9 PMID: 2153181 01/01/1990       35 Citations
  • Non-group A rotavirus infection associated with severe gastroenteritis in a bone marrow transplant patient. (Willoughby RE, Wee SB, Yolken RH) Pediatr Infect Dis J 1988 Feb;7(2):133-5 PMID: 2830587 02/01/1988       15 Citations
  • Last update: 02/02/2018
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