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Medical College of Wisconsin

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Roger H. Johnson PhD

Associate Professor

Institution: Medical College of Wisconsin
Department: Biophysics
Program: Research

Member of the Cancer Center
Member of the Center for Immunology

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Publications (79)

Team principles for successful interdisciplinary research teams. (Brown SA, Sparapani R, Osinski K, Zhang J, Blessing J, Cheng F, Hamid A, MohamadiPour MB, Lal JC, Kothari AN, Caraballo P, Noseworthy P, Johnson RH, Hansen K, Sun LY, Crotty B, Cheng YC, Echefu G, Doshi K, Olson J, Cardio-Oncology Artificial Intelligence Informatics & Precision (CAIP) Research Team Investigators) Am Heart J Plus 2023 Aug;32:100306 PMID: 38510201 PMCID: PMC10946054 SCOPUS ID: 2-s2.0-85163019573 03/21/2024

Team principles for successful interdisciplinary research teams (Brown SA, Sparapani R, Osinski K, Zhang J, Blessing J, Cheng F, Hamid A, MohamadiPour MB, Lal JC, Kothari AN, Caraballo P, Noseworthy P, Johnson RH, Hansen K, Sun LY, Crotty B, Cheng YC, Echefu G, Doshi K, Olson J) American Heart Journal Plus: Cardiology Research and Practice August 2023;32 SCOPUS ID: 2-s2.0-85163019573 08/01/2023

Targeting protein tyrosine phosphatases for CDK6-induced immunotherapy resistance. (Gao X, Wu Y, Chick JM, Abbott A, Jiang B, Wang DJ, Comte-Walters S, Johnson RH, Oberholtzer N, Nishimura MI, Gygi SP, Mehta A, Guttridge DC, Ball L, Mehrotra S, Sicinski P, Yu XZ, Wang H) Cell Rep 2023 Apr 25;42(4):112314 PMID: 37000627 PMCID: PMC10544673 SCOPUS ID: 2-s2.0-85151481968 04/01/2023

Establishing an interdisciplinary research team for cardio-oncology artificial intelligence informatics precision and health equity. (Brown SA, Sparapani R, Osinski K, Zhang J, Blessing J, Cheng F, Hamid A, Berman G, Lee K, BagheriMohamadiPour M, Lal JC, Kothari AN, Caraballo P, Noseworthy P, Johnson RH, Hansen K, Sun LY, Crotty B, Cheng YC, Olson J, Cardio-Oncology Artificial Intelligence Informatics & Precision (CAIP) Research Team Investigators) Am Heart J Plus 2022 Jan;13 PMID: 35434676 PMCID: PMC9012235 SCOPUS ID: 2-s2.0-85146432200 04/19/2022 13 Citations

Deep learning tools and modeling to estimate the temporal expression of cell cycle proteins from 2D still images. (Pécot T, Cuitiño MC, Johnson RH, Timmers C, Leone G) PLoS Comput Biol 2022 Mar;18(3):e1009949 PMID: 35286300 PMCID: PMC8947602 SCOPUS ID: 2-s2.0-85126910772 03/15/2022 3 Citations

Nuclear PFKP promotes CXCR4-dependent infiltration by T cell acute lymphoblastic leukemia. (Gao X, Qin S, Wu Y, Chu C, Jiang B, Johnson RH, Kuang D, Zhang J, Wang X, Mehta A, Tew KD, Leone GW, Yu XZ, Wang H) J Clin Invest 2021 Aug 16;131(16) PMID: 34255748 PMCID: PMC8363288 SCOPUS ID: 2-s2.0-85113146308 07/14/2021 21 Citations

Fragile X-related protein family: a double-edged sword in neurodevelopmental disorders and cancer. (Majumder M, Johnson RH, Palanisamy V) Crit Rev Biochem Mol Biol 2020 Oct;55(5):409-424 PMID: 32878499 PMCID: PMC7695039 SCOPUS ID: 2-s2.0-85090137717 09/04/2020 22 Citations

Mitochondrial protein import is regulated by p17/PERMIT to mediate lipid metabolism and cellular stress. (Oleinik N, Kim J, Roth BM, Selvam SP, Gooz M, Johnson RH, Lemasters JJ, Ogretmen B) Sci Adv 2019 Sep;5(9):eaax1978 PMID: 31535025 PMCID: PMC6739097 SCOPUS ID: 2-s2.0-85072264379 09/20/2019 35 Citations

Optical computed tomography for spatially isotropic four-dimensional imaging of live single cells. (Kelbauskas L, Shetty R, Cao B, Wang KC, Smith D, Wang H, Chao SH, Gangaraju S, Ashcroft B, Kritzer M, Glenn H, Johnson RH, Meldrum DR) Sci Adv 2017 Dec;3(12):e1602580 PMID: 29226240 PMCID: PMC5721812 SCOPUS ID: 2-s2.0-85041821749 12/12/2017 11 Citations

A platform for high-throughput bioenergy production phenotype characterization in single cells. (Kelbauskas L, Glenn H, Anderson C, Messner J, Lee KB, Song G, Houkal J, Su F, Zhang L, Tian Y, Wang H, Bussey K, Johnson RH, Meldrum DR) Sci Rep 2017 Mar 28;7:45399 PMID: 28349963 PMCID: PMC5368665 SCOPUS ID: 2-s2.0-85016622569 03/30/2017 10 Citations

Characterization and comparison of three microfabrication methods to generate out-of-plane microvortices for single cell rotation and 3D imaging (Shetty RM, Myers JR, Sreenivasulu M, Teller W, Vela J, Houkal J, Chao SH, Johnson RH, Kelbauskas L, Wang H, Meldrum DR) Journal of Micromechanics and Microengineering January 2017;27(1) SCOPUS ID: 2-s2.0-85005949723 01/01/2017 9 Citations

Vorinostat differentially alters 3D nuclear structure of cancer and non-cancerous esophageal cells. (Nandakumar V, Hansen N, Glenn HL, Han JH, Helland S, Hernandez K, Senechal P, Johnson RH, Bussey KJ, Meldrum DR) Sci Rep 2016 Aug 09;6:30593 PMID: 27503568 PMCID: PMC4977554 SCOPUS ID: 2-s2.0-84981290391 08/10/2016 3 Citations

Live single cell rotation using hydrodynamic microvortex flow and optical trapping (Shetty RM, Myers JR, Teller WL, Shabilla A, Smith D, Houkal J, Vela J, Chao S, Johnson RH, Kelbauskas L, Wang H, Meldrum DR) 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 2014:1545-1547 SCOPUS ID: 2-s2.0-84941670170 01/01/2014

Sensitizing cancer cells to TRAIL-induced death by micellar delivery of mitoxantrone. (Grandhi TS, Potta T, Taylor DJ, Tian Y, Johnson RH, Meldrum DR, Rege K) Nanomedicine (Lond) 2014;9(12):1775-88 PMID: 24195660 SCOPUS ID: 2-s2.0-84908222476 11/08/2013 6 Citations

Integrated metagenomic and metatranscriptomic analyses of microbial communities in the meso- and bathypelagic realm of north pacific ocean. (Wu J, Gao W, Johnson RH, Zhang W, Meldrum DR) Mar Drugs 2013 Oct 11;11(10):3777-801 PMID: 24152557 PMCID: PMC3826135 SCOPUS ID: 2-s2.0-84887078104 10/25/2013 34 Citations

Single-cell analysis reveals early manifestation of cancerous phenotype in pre-malignant esophageal cells. (Wang J, Shi X, Johnson RH, Kelbauskas L, Zhang W, Meldrum DR) PLoS One 2013;8(10):e75365 PMID: 24116039 PMCID: PMC3792915 SCOPUS ID: 2-s2.0-84860187343 10/12/2013 135 Citations

A physical sciences network characterization of non-tumorigenic and metastatic cells. (Physical Sciences - Oncology Centers Network, Agus DB, Alexander JF, Arap W, Ashili S, Aslan JE, Austin RH, Backman V, Bethel KJ, Bonneau R, Chen WC, Chen-Tanyolac C, Choi NC, Curley SA, Dallas M, Damania D, Davies PC, Decuzzi P, Dickinson L, Estevez-Salmeron L, Estrella V, Ferrari M, Fischbach C, Foo J, Fraley SI, Frantz C, Fuhrmann A, Gascard P, Gatenby RA, Geng Y, Gerecht S, Gillies RJ, Godin B, Grady WM, Greenfield A, Hemphill C, Hempstead BL, Hielscher A, Hillis WD, Holland EC, Ibrahim-Hashim A, Jacks T, Johnson RH, Joo A, Katz JE, Kelbauskas L, Kesselman C, King MR, Konstantopoulos K, Kraning-Rush CM, Kuhn P, Kung K, Kwee B, Lakins JN, Lambert G, Liao D, Licht JD, Liphardt JT, Liu L, Lloyd MC, Lyubimova A, Mallick P, Marko J, McCarty OJ, Meldrum DR, Michor F, Mumenthaler SM, Nandakumar V, O'Halloran TV, Oh S, Pasqualini R, Paszek MJ, Philips KG, Poultney CS, Rana K, Reinhart-King CA, Ros R, Semenza GL, Senechal P, Shuler ML, Srinivasan S, Staunton JR, Stypula Y, Subramanian H, Tlsty TD, Tormoen GW, Tseng Y, van Oudenaarden A, Verbridge SS, Wan JC, Weaver VM, Widom J, Will C, Wirtz D, Wojtkowiak J, Wu PH) Sci Rep 2013;3:1449 PMID: 23618955 PMCID: PMC3636513 SCOPUS ID: 2-s2.0-84878282427 04/27/2013 129 Citations

Using fluorine-containing amphiphilic random copolymers to manipulate the quantum yields of aggregation-induced emission fluorophores in aqueous solutions and the use of these polymers for fluorescent bioimaging. (Lu H, Su F, Mei Q, Tian Y, Tian W, Johnson RH, Meldrum DR) J Mater Chem 2012 May 01;22(19):9890-9900 PMID: 23397360 PMCID: PMC3565462 02/12/2013

On-chip isotachophoresis separation of functional DNA origami capture nanoarrays from cell lysate (Mei Q, Johnson RH, Wei X, Su F, Liu Y, Kelbauskas L, Lindsay S, Meldrum DR, Yan H) Nano Research October 2013;6(10):712-719 SCOPUS ID: 2-s2.0-84886096990 01/01/2013 20 Citations

Rotation of cells and cell clusters in culture media for optical computed tomography (Wang H, Stanley M, Elango IS, Shetty RM, Teller W, Shabilla A, Limsirichai P, Zhu H, Houkal J, Smith D, Chao SH, Kelbauskas L, Johnson RH, Meldrum DR) 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 2013;2:1090-1092 SCOPUS ID: 2-s2.0-84907378132 01/01/2013 1 Citation

Multiple sensor arrays for single cell metabolic analysis (Song G, Shetty RM, Zhu H, Ashili S, Zhang L, Kim G, Shabilla A, Teller W, Mei Q, Kelbauskas L, Tian Y, Wang H, Johnson RH, Meldrum DR) Proceedings of IEEE Sensors 2013 SCOPUS ID: 2-s2.0-84893984469 01/01/2013 1 Citation

Surface tension-controlled three-dimensional water molds: Theory and applications (Goff CM, Chao SH, Johnson RH, Meldrum DR) Microfluidics and Nanofluidics December 2012;13(6):891-897 SCOPUS ID: 2-s2.0-84871761633 12/01/2012 6 Citations

Simulation and experimental characterization of microscopically accessible hydrodynamic microvortices (Zhang W, Frakes DH, Babiker H, Chao SH, Youngbull C, Johnson RH, Meldrum DR) Micromachines 2012;3(2):529-541 SCOPUS ID: 2-s2.0-84874450706 12/01/2012 5 Citations

Conformal mapping of nuclei in 3D tomographic cell images to assess shape heterogeneity (Nandakumar V, An X, Wang Y, Johnson R, Meldrum D) Proceedings - International Symposium on Biomedical Imaging 2012:222-225 SCOPUS ID: 2-s2.0-84864833725 08/15/2012 5 Citations

Using fluorine-containing amphiphilic random copolymers to manipulate the quantum yields of aggregation-induced emission fluorophores in aqueous solutions and the use of these polymers for fluorescent bioimaging (Lu H, Su F, Mei Q, Tian Y, Tian W, Johnson RH, Meldrum DR) Journal of Materials Chemistry 21 May 2012;22(19):9890-9900 SCOPUS ID: 2-s2.0-84860378382 05/21/2012 70 Citations

Method for physiologic phenotype characterization at the single-cell level in non-interacting and interacting cells. (Kelbauskas L, Ashili SP, Houkal J, Smith D, Mohammadreza A, Lee KB, Forrester J, Kumar A, Anis YH, Paulson TG, Youngbull CA, Tian Y, Holl MR, Johnson RH, Meldrum DR) J Biomed Opt 2012 Mar;17(3):037008 PMID: 22502580 PMCID: PMC3602818 SCOPUS ID: 2-s2.0-84864922062 04/17/2012 19 Citations

Nanostructured oxygen sensor--using micelles to incorporate a hydrophobic platinum porphyrin. (Su F, Alam R, Mei Q, Tian Y, Youngbull C, Johnson RH, Meldrum DR) PLoS One 2012;7(3):e33390 PMID: 22457758 PMCID: PMC3310867 SCOPUS ID: 2-s2.0-84863353677 03/30/2012 44 Citations

A series of poly[N-(2-hydroxypropyl)methacrylamide] copolymers with anthracene-derived fluorophores showing aggregation-induced emission properties for bioimaging. (Lu H, Su F, Mei Q, Zhou X, Tian Y, Tian W, Johnson RH, Meldrum DR) J Polym Sci A Polym Chem 2012 Mar 01;50(5):890-899 PMID: 22287826 PMCID: PMC3266372 SCOPUS ID: 2-s2.0-84863012618 01/31/2012 50 Citations

Isotropic 3D nuclear morphometry of normal, fibrocystic and malignant breast epithelial cells reveals new structural alterations. (Nandakumar V, Kelbauskas L, Hernandez KF, Lintecum KM, Senechal P, Bussey KJ, Davies PC, Johnson RH, Meldrum DR) PLoS One 2012;7(1):e29230 PMID: 22242161 PMCID: PMC3252316 SCOPUS ID: 2-s2.0-84855387742 01/14/2012 53 Citations

A statistical framework for multiparameter analysis at the single-cell level. (Torres-García W, Ashili S, Kelbauskas L, Johnson RH, Zhang W, Runger GC, Meldrum DR) Mol Biosyst 2012 Mar;8(3):804-17 PMID: 22222464 SCOPUS ID: 2-s2.0-84863125256 01/10/2012 3 Citations

A new highly selective fluorescent K+ sensor. (Zhou X, Su F, Tian Y, Youngbull C, Johnson RH, Meldrum DR) J Am Chem Soc 2011 Nov 23;133(46):18530-3 PMID: 22026580 PMCID: PMC3223084 SCOPUS ID: 2-s2.0-83055161605 10/27/2011 145 Citations

An FRET-based ratiometric chemosensor for in vitro cellular fluorescence analyses of pH. (Zhou X, Su F, Lu H, Senechal-Willis P, Tian Y, Johnson RH, Meldrum DR) Biomaterials 2012 Jan;33(1):171-80 PMID: 21982292 PMCID: PMC3208745 SCOPUS ID: 2-s2.0-82855172094 10/11/2011 159 Citations

Platinum (II) Porphyrin-Containing Thermoresponsive Poly(N-isopropylacrylamide) Copolymer as Fluorescence Dual Oxygen and Temperature Sensor. (Zhou X, Su F, Tian Y, Johnson RH, Meldrum DR) Sens Actuators B Chem 2011 Nov 28;159(1):135-141 PMID: 21927540 PMCID: PMC3171833 SCOPUS ID: 2-s2.0-80052314241 09/20/2011 33 Citations

Triazacryptand-based fluorescent sensors for extracellular and intracellular K+ sensing. (Zhou X, Su F, Gao W, Tian Y, Youngbull C, Johnson RH, Meldrum DR) Biomaterials 2011 Nov;32(33):8574-83 PMID: 21855134 PMCID: PMC3177004 SCOPUS ID: 2-s2.0-80052970870 08/23/2011 51 Citations

Automated platform for multiparameter stimulus response studies of metabolic activity at the single-cell level (Ashili SP, Kelbauskas L, Houkal J, Smith D, Tian Y, Youngbull C, Zhu H, Anis YH, Hupp M, Lee KB, Kumar AV, Vela J, Shabilla A, Johnson RH, Holl MR, Meldrum DR) Proceedings of SPIE - The International Society for Optical Engineering 2011;7929 SCOPUS ID: 2-s2.0-79957980210 06/09/2011 2 Citations

Quantitative single-cell gene expression measurements of multiple genes in response to hypoxia treatment. (Zeng J, Wang J, Gao W, Mohammadreza A, Kelbauskas L, Zhang W, Johnson RH, Meldrum DR) Anal Bioanal Chem 2011 Jul;401(1):3-13 PMID: 21614642 SCOPUS ID: 2-s2.0-79960555292 05/27/2011 11 Citations

A novel method for multiparameter physiological phenotype characterization at the single-cell level (Kelbauskas L, Ashili S, Houkal J, Smith D, Mohammadreza A, Lee K, Kumar A, Anis Y, Paulson T, Youngbull C, Tian Y, Johnson R, Holl M, Meldrum D) Progress in Biomedical Optics and Imaging - Proceedings of SPIE 2011;7902 SCOPUS ID: 2-s2.0-79954481966 04/20/2011 1 Citation

Diaphragm pico-liter pump for single-cell manipulation. (Anis Y, Houkal J, Holl M, Johnson R, Meldrum D) Biomed Microdevices 2011 Aug;13(4):651-9 PMID: 21494795 PMCID: PMC6881176 SCOPUS ID: 2-s2.0-80053911002 04/16/2011 23 Citations

Stability of DNA origami nanoarrays in cell lysate. (Mei Q, Wei X, Su F, Liu Y, Youngbull C, Johnson R, Lindsay S, Yan H, Meldrum D) Nano Lett 2011 Apr 13;11(4):1477-82 PMID: 21366226 PMCID: PMC3319871 SCOPUS ID: 2-s2.0-79954497718 03/04/2011 281 Citations

Integrative analysis of transcriptomic and proteomic data of Shewanella oneidensis: missing value imputation using temporal datasets. (Torres-García W, Brown SD, Johnson RH, Zhang W, Runger GC, Meldrum DR) Mol Biosyst 2011 Apr;7(4):1093-104 PMID: 21212895 SCOPUS ID: 2-s2.0-79952650377 01/08/2011 10 Citations

Quantitative characterization of preneoplastic progression using single-cell computed tomography and three-dimensional karyometry. (Nandakumar V, Kelbauskas L, Johnson R, Meldrum D) Cytometry A 2011 Jan;79(1):25-34 PMID: 21182180 PMCID: PMC3068856 SCOPUS ID: 2-s2.0-78650474099 12/25/2010 27 Citations

Influence of Matrices on Oxygen Sensing of Three Sensing Films with Chemically Conjugated Platinum Porphyrin Probes and Preliminary Application for Monitoring of Oxygen Consumption of Escherichia coli (E. coli). (Tian Y, Shumway BR, Gao W, Youngbull C, Holl MR, Johnson RH, Meldrum DR) Sens Actuators B Chem 2010 Oct 28;150(2):579-587 PMID: 21076638 PMCID: PMC2976577 SCOPUS ID: 2-s2.0-77958474975 11/16/2010 49 Citations

A series of naphthalimide derivatives as intra and extracellular pH sensors. (Tian Y, Su F, Weber W, Nandakumar V, Shumway BR, Jin Y, Zhou X, Holl MR, Johnson RH, Meldrum DR) Biomaterials 2010 Oct;31(29):7411-22 PMID: 20619451 PMCID: PMC2940253 SCOPUS ID: 2-s2.0-77955276024 07/14/2010 113 Citations

Dually Fluorescent Sensing of pH and Dissolved Oxygen Using a Membrane Made from Polymerizable Sensing Monomers. (Tian Y, Shumway BR, Youngbull AC, Li Y, Jen AK, Johnson RH, Meldrum DR) Sens Actuators B Chem 2010 Jun 03;147(2):714-722 PMID: 20543884 PMCID: PMC2882062 SCOPUS ID: 2-s2.0-77953135783 06/15/2010 46 Citations

An improved one-tube RT-PCR protocol for analyzing single-cell gene expression in individual mammalian cells. (Li Y, Thompson H, Hemphill C, Hong F, Forrester J, Johnson RH, Zhang W, Meldrum DR) Anal Bioanal Chem 2010 Jul;397(5):1853-9 PMID: 20490471 SCOPUS ID: 2-s2.0-77953811012 05/22/2010 17 Citations

Microfluidic device for transport and observation of single cells (Merza SA, Posner JD, Anis YH, Young AC, Johnson RH, Meldrum DR) ASME International Mechanical Engineering Congress and Exposition, Proceedings 2010;9(PART C):2213-2220 SCOPUS ID: 2-s2.0-77954296747 01/01/2010 2 Citations

Arterial tree morphometry (Johnson R) Handbook of Medical Image Processing and Analysis 2009:317-339 SCOPUS ID: 2-s2.0-84884777658 12/01/2009 1 Citation

Integrative analysis of transcriptomic and proteomic data of Desulfovibrio vulgaris: a non-linear model to predict abundance of undetected proteins. (Torres-García W, Zhang W, Runger GC, Johnson RH, Meldrum DR) Bioinformatics 2009 Aug 01;25(15):1905-14 PMID: 19447782 PMCID: PMC2712339 SCOPUS ID: 2-s2.0-67650742246 05/19/2009 29 Citations

A short scan helical FDK cone beam algorithm based on surfaces satisfying the Tuy's condition (Hu J, Tam K, Johnson RH, Qi J) IEEE Nuclear Science Symposium Conference Record 2004;5:2760-2764 SCOPUS ID: 2-s2.0-23844518539 12/01/2004 1 Citation

A simple derivation and analysis of a helical cone beam tomographic algorithm for long object imaging via a novel definition of region of interest. (Hu J, Tam K, Johnson RH) Phys Med Biol 2004 Jan 21;49(2):205-25 PMID: 15083667 SCOPUS ID: 2-s2.0-0942266356 04/16/2004 4 Citations

Improved iterative algorithm for sparse object reconstruction and its performance evaluation with Micro-CT data (Li M, Kudo H, Hu J, Johnson RH) IEEE Transactions on Nuclear Science June 2004;51(3 II):659-666 SCOPUS ID: 2-s2.0-3342925349 01/01/2004 24 Citations

SPECT imaging of pulmonary blood flow in a rat (Wietholt C, Molthen RC, Johnson RH, Dawson CA, Clough AV) Proceedings of SPIE - The International Society for Optical Engineering 2003;5031:252-261 SCOPUS ID: 2-s2.0-0042782833 09/22/2003 4 Citations

A Helical Cone Beam Algorithm for Large Cone Angles with Minimal Overscan (Hu J, Johnson RH) IEEE Nuclear Science Symposium and Medical Imaging Conference 2002;2:1013-1017 SCOPUS ID: 2-s2.0-0142179102 12/01/2002 2 Citations

Sparse Object Reconstruction from a Limited Number of Projections Using the Linear Programming (Li M, Kudo H, Hu J, Johnson R) IEEE Nuclear Science Symposium and Medical Imaging Conference 2002;2:989-993 SCOPUS ID: 2-s2.0-0142148094 12/01/2002

Simple Cone Beam Backprojection Reconstruction for Robust Skeletonization of 3D Vascular Trees (Hanger CC, Haworth ST, Molthen RC, Dawson CA, Johnson RH) IEEE Nuclear Science Symposium and Medical Imaging Conference 2002;2:1003-1007 SCOPUS ID: 2-s2.0-0142241188 12/01/2002

Quasi-exact helical cone beam reconstruction for micro CT (Hu J, Johnson R, Molthen R, Haworth S, Dawson C) Proceedings - International Symposium on Biomedical Imaging 2002;2002-January:681-684 SCOPUS ID: 2-s2.0-84948667300 01/01/2002

Pulmonary arterial morphometry from microfocal X-ray computed tomography. (Karau KL, Molthen RC, Dhyani A, Haworth ST, Hanger CC, Roerig DL, Johnson RH, Dawson CA) Am J Physiol Heart Circ Physiol 2001 Dec;281(6):H2747-56 PMID: 11709444 SCOPUS ID: 2-s2.0-0035658460 11/16/2001 42 Citations

Microfocal X-ray CT imaging and pulmonary arterial distensibility in excised rat lungs. (Karau KL, Johnson RH, Molthen RC, Dhyani AH, Haworth ST, Hanger CC, Roerig DL, Dawson CA) Am J Physiol Heart Circ Physiol 2001 Sep;281(3):H1447-57 PMID: 11514318 SCOPUS ID: 2-s2.0-0034829987 08/22/2001 48 Citations

Pulmonary arterial remodeling revealed by microfocal x-ray tomography (Karau KL, Molthen RC, Johnson RH, Dhyani AH, Haworth ST, Dawson CA) Proceedings of SPIE - The International Society for Optical Engineering 2001;4321:282-287 SCOPUS ID: 2-s2.0-0034875574 01/01/2001 2 Citations

Using graphics hardware for CT reconstruction (Molthen R, Johnson R, Dawson C) Annals of Biomedical Engineering 2000;28(SUPPL. 1) SCOPUS ID: 2-s2.0-0034516587 12/01/2000

Structural and mechanical consequences of arterial remodeling in a rat model of pulmonary hypertension assessed using micro-CT (Johnson R, Karau K, Molthen R, Dawson C) Annals of Biomedical Engineering 2000;28(SUPPL. 1) SCOPUS ID: 2-s2.0-0034499662 12/01/2000

Helical cone beam micro-CT for small animal imaging (Hu J, Johnson R, Molthen R, Haworth S, Dawson C) Annals of Biomedical Engineering 2000;28(SUPPL. 1) SCOPUS ID: 2-s2.0-0034499668 12/01/2000

An iterative approach to the beam hardening correction in cone beam CT. (Hsieh J, Molthen RC, Dawson CA, Johnson RH) Med Phys 2000 Jan;27(1):23-9 PMID: 10659734 SCOPUS ID: 2-s2.0-0033983855 02/05/2000 237 Citations

Micro-CT image-derived metrics quantify arterial wall distensibility reduction in a rat model of pulmonary hypertension (Johnson RH, Karau KL, Molthen RC, Haworth ST, Dawson CA) Proceedings of SPIE - The International Society for Optical Engineering 2000;3978:320-330 SCOPUS ID: 2-s2.0-0033736821 01/01/2000 6 Citations

Complexity in pulmonary arterial tree structure-function (Dawson CA, Karau KL, Krenz GS, Johnson RH) Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings 1999;1:352 SCOPUS ID: 2-s2.0-0033353949 12/01/1999

3D X-ray microtomography applied to structural and mechanical characterization of arterial trees (Johnson RH, Molthen RC, Wietholt C, Karau KL, Hanger CC, Dawson CA) Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings 1999;2:1038 SCOPUS ID: 2-s2.0-0033320468 12/01/1999

Quantification of pulmonary arterial wall distensibility using parameters extracted from volumetric micro-CT images (Johnson RH, Karau KL, Molthen RC, Dawson CA) Proceedings of SPIE - The International Society for Optical Engineering 1999;3772:15-23 SCOPUS ID: 2-s2.0-0032596682 01/01/1999 6 Citations

Exploiting self-similarity of arterial trees to reduce the complexity of image analysis (Johnson RH, Karau KL, Molthen RC, Dawson CA) Proceedings of SPIE - The International Society for Optical Engineering 1999;3660:351-361 SCOPUS ID: 2-s2.0-0032593657 01/01/1999 9 Citations

Automated detection of BB pixel clusters in digital fluoroscopic images. (Cho PS, Johnson RH) Phys Med Biol 1998 Sep;43(9):2677-83 PMID: 9755954 SCOPUS ID: 2-s2.0-0031663998 10/02/1998 14 Citations

Feldkamp and circle-and-line cone-beam reconstruction for 3D micro-CT of vascular networks. (Johnson RH, Hu H, Haworth ST, Cho PS, Dawson CA, Linehan JH) Phys Med Biol 1998 Apr;43(4):929-40 PMID: 9572516 SCOPUS ID: 2-s2.0-0031972279 05/08/1998 57 Citations

Cone-beam CT from width-truncated projections. (Cho PS, Rudd AD, Johnson RH) Comput Med Imaging Graph 1996;20(1):49-57 PMID: 8891422 SCOPUS ID: 2-s2.0-0029763942 01/01/1996 64 Citations

Effects of number of views, cone angle, detector bit depth, and projection noise level on the SNR in cone-beam reconstruction (Johnson RH, Wu X, Cho PS) Proceedings of SPIE - The International Society for Optical Engineering 1996;2708:340-350 SCOPUS ID: 2-s2.0-0029701764 01/01/1996

Determinants of signal to noise ratio in conebeam image reconstruction using the Feldkamp algorithm (Wu X, Johnson RH, Cho PS) Southern Biomedical Engineering Conference - Proceedings 1996:263-265 SCOPUS ID: 2-s2.0-0029694498 01/01/1996

Cone-beam CT for radiotherapy applications. (Cho PS, Johnson RH, Griffin TW) Phys Med Biol 1995 Nov;40(11):1863-83 PMID: 8587937 SCOPUS ID: 2-s2.0-0029589221 11/01/1995 149 Citations

3D microanalysis of tissue volumes using dual-energy conebeam x-ray microtomography (Johnson RH) Proceedings - Annual Meeting, Microscopy Society of America 1993:652-653 SCOPUS ID: 2-s2.0-0027707877 12/01/1993 2 Citations

Dual-energy x-ray microscopy and microtomography (Johnson RH, Nelson AC) Proceedings of the Annual Conference on Engineering in Medicine and Biology 1993;15(pt 1):497-498 SCOPUS ID: 2-s2.0-0027841392 12/01/1993

A new set of calibration standards for estimating the fat and mineral content of vertebrae via dual energy QCT. (Goodsitt MM, Johnson RH, Chesnut CH 3rd) Bone Miner 1991 Jun;13(3):217-33 PMID: 1863810 SCOPUS ID: 2-s2.0-0025753370 06/01/1991 18 Citations

Optimal information retrieval from complex low frequency backgrounds in medical images (Johnson RH, Nelson AC, Haralick RM, Goodsitt MM) Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings 1989;11 pt 2:384-385 SCOPUS ID: 2-s2.0-0024878430 12/01/1989 3 Citations

3-d display of magnetic resonance imaging of the spine (Nelson AC, Johnson RH, Kim Y, Haralick RM, Desoto LA, Anderson PA) Proceedings of SPIE - The International Society for Optical Engineering 8 June 1988;902:103-112 SCOPUS ID: 2-s2.0-84910967887 06/08/1988 4 Citations

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This site is a collaborative effort of the Medical College of Wisconsin and the Clinical and Translational Science Institute (CTSI), part of the Clinical and Translational Science Award program funded by the National Center for Advancing Translational Sciences (Grant Number 2UL1TR001436) at the National Institutes of Health (NIH).

Profiles for MCW, MU, MSOE, UWM, BCW, CW, Froedtert, and VA Faculty

Roger H. Johnson PhD

Associate Professor

Publications (79)