Medical College of Wisconsin
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Scott K. Van Why MD


Institution: Medical College of Wisconsin
Department: Pediatrics
Division: Nephrology


  • Mice with an absent stress response are protected against ischemic renal injury. (Sreedharan R, Chen S, Miller M, Haribhai D, Williams CB, Van Why SK) Kidney Int 2014 Sep;86(3):515-24 PMID 24805105
  • Donor and recipient BKV-specific IgG antibody and posttransplantation BKV infection: a prospective single-center study. (Sood P, Senanayake S, Sujeet K, Medipalli R, Van-Why SK, Cronin DC, Johnson CP, Hariharan S) Transplantation 2013 Mar 27;95(6):896-902 PMID 23511214
  • Chromosome substitution modulates resistance to ischemia reperfusion injury in Brown Norway rats. (Basile DP, Dwinell MR, Wang SJ, Shames BD, Donohoe DL, Chen S, Sreedharan R, Van Why SK) Kidney Int 2013 Feb;83(2):242-50 PMID 23235564
  • Renal function and proteinuria after successful immunosuppressive therapies in patients with FSGS. (Hogg RJ, Friedman A, Greene T, Radeva M, Budisavljevic MN, Gassman J, Gipson DS, Jefferson JA, John EG, Kaskel FJ, Moudgil A, Moxey-Mims M, Ortiz LA, Schelling JR, Schnaper W, Srivastava T, Trachtman H, Vehaskari VM, Wong C, Woronieki RP, Van Why SK, Zolotnitskaya A) Clin J Am Soc Nephrol 2013 Feb;8(2):211-8 PMID 23143503
  • Protective effect of 20-HETE analogues in experimental renal ischemia reperfusion injury. (Regner KR, Zuk A, Van Why SK, Shames BD, Ryan RP, Falck JR, Manthati VL, McMullen ME, Ledbetter SR, Roman RJ) Kidney Int 2009 Mar;75(5):511-7 PMID 19052533
  • Oxidant-mediated apoptosis in proximal tubular epithelial cells following ATP depletion and recovery. (Maenpaa CJ, Shames BD, Van Why SK, Johnson CP, Nilakantan V) Free Radic Biol Med 2008 Feb 15;44(4):518-26 PMID 17997382
  • Favorable balance of anti-oxidant/pro-oxidant systems and ablated oxidative stress in Brown Norway rats in renal ischemia-reperfusion injury. (Nilakantan V, Hilton G, Maenpaa C, Van Why SK, Pieper GM, Johnson CP, Shames BD) Mol Cell Biochem 2007 Oct;304(1-2):1-11 PMID 17458515
  • Resistance to ischemic acute renal failure in the Brown Norway rat: a new model to study cytoprotection. (Basile DP, Donohoe D, Cao X, Van Why SK) Kidney Int 2004 Jun;65(6):2201-11 PMID 15149333
  • Prevention of acute ischemic renal failure by targeted delivery of growth factors to the proximal tubule in transgenic mice: the efficacy of parathyroid hormone-related protein and hepatocyte growth factor. (Fiaschi-Taesch NM, Santos S, Reddy V, Van Why SK, Philbrick WF, Ortega A, Esbrit P, Orloff JJ, Garcia-Ocaña A) J Am Soc Nephrol 2004 Jan;15(1):112-25 PMID 14694163
  • Hsp27 associates with actin and limits injury in energy depleted renal epithelia. (Van Why SK, Mann AS, Ardito T, Thulin G, Ferris S, Macleod MA, Kashgarian M, Siegel NJ) J Am Soc Nephrol 2003 Jan;14(1):98-106 PMID 12506142
  • Functional activation of heat shock factor and hypoxia-inducible factor in the kidney. (Eickelberg O, Seebach F, Riordan M, Thulin G, Mann A, Reidy KH, Van Why SK, Kashgarian M, Siegel N) J Am Soc Nephrol 2002 Aug;13(8):2094-101 PMID 12138141
  • Ischemic conditioning prevents Na,K-ATPase dissociation from the cytoskeletal cellular fraction after repeat renal ischemia in rats. (Aufricht C, Bidmon B, Ruffingshofer D, Regele H, Herkner K, Siegel NJ, Kashgarian M, Van Why SK) Pediatr Res 2002 Jun;51(6):722-7 PMID 12032267
  • Pneumothoraces complicating systemic lupus erythematosus with nephritis. (Wilhelm M, Van Why SK) Pediatr Nephrol 2002 Apr;17(4):261-3 PMID 11956878
  • Thresholds for cellular disruption and activation of the stress response in renal epithelia. (van Why SK, Kim S, Geibel J, Seebach FA, Kashgarian M, Siegel NJ) Am J Physiol 1999 Aug;277(2 Pt 2):F227-34 PMID 10444577
  • Expression and role of parathyroid hormone-related protein in human renal proximal tubule cells during recovery from ATP depletion. (García-Ocaña A, Galbraith SC, Van Why SK, Yang K, Golovyan L, Dann P, Zager RA, Stewart AF, Siegel NJ, Orloff JJ) J Am Soc Nephrol 1999 Feb;10(2):238-44 PMID 10215322
  • Heat shock proteins in renal injury and recovery. (Van Why SK, Siegel NJ) Curr Opin Nephrol Hypertens 1998 Jul;7(4):407-12 PMID 9690040
  • Hypernatremia in infancy. (Mishkin MB, Simonet M, Lawrence C, Van Why SK) Curr Opin Pediatr 1998 Apr;10(2):156-60 PMID 9608893
  • ATP releases HSP-72 from protein aggregates after renal ischemia. (Aufricht C, Lu E, Thulin G, Kashgarian M, Siegel NJ, Van Why SK) Am J Physiol 1998 Feb;274(2 Pt 2):F268-74 PMID 9486221
  • Heat-shock protein 25 induction and redistribution during actin reorganization after renal ischemia. (Aufricht C, Ardito T, Thulin G, Kashgarian M, Siegel NJ, Van Why SK) Am J Physiol 1998 Jan;274(1 Pt 2):F215-22 PMID 9458842
  • Severe hypertension without urinary abnormalities in a patient with Henoch-Schönlein purpura. (Whyte DA, Van Why SK, Siegel NJ) Pediatr Nephrol 1997 Dec;11(6):750-1 PMID 9438659
  • Activation of heat-shock transcription factor by graded reductions in renal ATP, in vivo, in the rat. (Van Why SK, Mann AS, Thulin G, Zhu XH, Kashgarian M, Siegel NJ) J Clin Invest 1994 Oct;94(4):1518-23 PMID 7929828
  • Expression and molecular regulation of Na(+)-K(+)-ATPase after renal ischemia. (Van Why SK, Mann AS, Ardito T, Siegel NJ, Kashgarian M) Am J Physiol 1994 Jul;267(1 Pt 2):F75-85 PMID 8048568
  • Altered renovascular resistance after spontaneous recovery from hemolytic uremic syndrome. (O'Brien JA, Van Why SK, Keller MS, Gaudio KM, Kennedy TL, Siegel NJ) Yale J Biol Med 1994 Jan-Apr;67(1-2):1-14 PMID 7645308
  • Expression of parathyroid hormone-related protein in the rat glomerulus and tubule during recovery from renal ischemia. (Soifer NE, Van Why SK, Ganz MB, Kashgarian M, Siegel NJ, Stewart AF) J Clin Invest 1993 Dec;92(6):2850-7 PMID 8254039
  • ddAVP does not stimulate acute changes in levels of medullary trimethylamines in humans. (Avison MJ, Van Why SK, Siegel NJ) J Am Soc Nephrol 1993 Dec;4(6):1379-84 PMID 8130365
  • Abdominal symptoms as presentation of hypertensive crisis. (Van Why SK, Boydstun II, Gaudio KM, Siegel NJ) Am J Dis Child 1993 Jun;147(6):638-41 PMID 8506831
  • Induction and intracellular localization of HSP-72 after renal ischemia. (Van Why SK, Hildebrandt F, Ardito T, Mann AS, Siegel NJ, Kashgarian M) Am J Physiol 1992 Nov;263(5 Pt 2):F769-75 PMID 1443167
  • Renal insufficiency after bone marrow transplantation in children. (Van Why SK, Friedman AL, Wei LJ, Hong R) Bone Marrow Transplant 1991 May;7(5):383-8 PMID 2070148
  • Last update: 07/13/2014