Medical College of Wisconsin
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Tayler D. Sheahan PhD

Tayler D. Sheahan PhD profile photo picture

Assistant Professor

Institution: Medical College of Wisconsin
Department: Cell Biology Neurobiology and Anatomy

Member of the Cardiovascular Research Center


Publications (18)

  • Peripheral kappa opioid receptors modulate cold hypersensitivity in a mouse model of chemotherapy-induced neuropathy. (Madasu MK, Thang LV, Ohazurume CC, Chebrolu S, Houghten RA, Bandla S, Sheahan TD, Foshage AM, McLaughlin JP, McCall JG, Al-Hasani R) Pain 2026 Jul 07 PMID: 42402893    
  • Scratching promotes allergic inflammation and host defense via neurogenic mast cell activation. (Liu AW, Zhang YR, Chen CS, Edwards TN, Ozyaman S, Ramcke T, McKendrick LM, Weiss ES, Gillis JE, Laughlin CR, Randhawa SK, Phelps CM, Kurihara K, Kang HM, Nguyen SN, Kim J, Sheahan TD, Ross SE, Meisel M, Sumpter TL, Kaplan DH) Science 2025 Jan 31;387(6733):eadn9390 PMID: 39883751 PMCID: PMC11983162 SCOPUS ID: 2-s2.0-85217623703 01/30/2025       49 Citations
  • Intrinsic adaptive plasticity in mouse and human sensory neurons. (McIlvried LA, Del Rosario JS, Pullen MY, Wangzhou A, Sheahan TD, Shepherd AJ, Slivicki RA, Lemen JA, Price TJ, Copits BA, Gereau RW 4th) J Gen Physiol 2025 Jan 06;157(1) PMID: 39688836 PMCID: PMC11651306 SCOPUS ID: 2-s2.0-85212890395 12/17/2024       6 Citations
  • Kappa opioids inhibit spinal output neurons to suppress itch. (Sheahan TD, Warwick CA, Cui AY, Baranger DAA, Perry VJ, Smith KM, Manalo AP, Nguyen EK, Koerber HR, Ross SE) Sci Adv 2024 Sep 27;10(39):eadp6038 PMID: 39321286 PMCID: PMC11423883 SCOPUS ID: 2-s2.0-85204941573 09/25/2024       19 Citations
  • The Drosophila drop-dead gene is required for eggshell integrity. (Sheahan TD, Grewal A, Korthauer LE, Blumenthal EM) PLoS One 2023;18(12):e0295412 PMID: 38051756 PMCID: PMC10697589 SCOPUS ID: 2-s2.0-85178850919 12/06/2023    
  • Identification of a convergent spinal neuron population that encodes itch. (Sheahan TD, Warwick CA, Cui AY, Baranger DAA, Perry VJ, Smith KM, Manalo AP, Nguyen EK, Koerber HR, Ross SE) bioRxiv 2023 Nov 08 PMID: 37873278 PMCID: PMC10592866 10/24/2023    
  • Intrinsic Homeostatic Plasticity in Mouse and Human Sensory Neurons. (McIlvried LA, Del Rosario JS, Pullen MY, Wangzhou A, Sheahan TD, Shepherd AJ, Slivicki RA, Lemen JA, Price TJ, Copits BA, Gereau RW 4th) bioRxiv 2023 Jun 14 PMID: 37398430 PMCID: PMC10312743 07/03/2023    
  • The Drosophila drop-dead gene is required for eggshell integrity. (Sheahan TD, Grewal A, Korthauer LE, Blumenthal EM) bioRxiv 2023 May 12 PMID: 37163052 PMCID: PMC10168300 05/10/2023    
  • Cell type-specific calcium imaging of central sensitization in mouse dorsal horn. (Warwick C, Salsovic J, Hachisuka J, Smith KM, Sheahan TD, Chen H, Ibinson J, Koerber HR, Ross SE) Nat Commun 2022 Sep 03;13(1):5199 PMID: 36057681 PMCID: PMC9440908 SCOPUS ID: 2-s2.0-85137168872 09/04/2022       28 Citations
  • MrgprdCre lineage neurons mediate optogenetic allodynia through an emergent polysynaptic circuit. (Warwick C, Cassidy C, Hachisuka J, Wright MC, Baumbauer KM, Adelman PC, Lee KH, Smith KM, Sheahan TD, Ross SE, Koerber HR) Pain 2021 Jul 01;162(7):2120-2131 PMID: 34130311 PMCID: PMC8206522 SCOPUS ID: 2-s2.0-85108247993 06/16/2021       32 Citations
  • The Neurokinin-1 Receptor is Expressed with Gastrin-Releasing Peptide Receptor in Spinal Interneurons and Modulates Itch. (Sheahan TD, Warwick CA, Fanien LG, Ross SE) J Neurosci 2020 Nov 11;40(46):8816-8830 PMID: 33051347 PMCID: PMC7659450 SCOPUS ID: 2-s2.0-85096062416 10/15/2020       27 Citations
  • Kappa Opioid Receptor Distribution and Function in Primary Afferents. (Snyder LM, Chiang MC, Loeza-Alcocer E, Omori Y, Hachisuka J, Sheahan TD, Gale JR, Adelman PC, Sypek EI, Fulton SA, Friedman RL, Wright MC, Duque MG, Lee YS, Hu Z, Huang H, Cai X, Meerschaert KA, Nagarajan V, Hirai T, Scherrer G, Kaplan DH, Porreca F, Davis BM, Gold MS, Koerber HR, Ross SE) Neuron 2018 Sep 19;99(6):1274-1288.e6 PMID: 30236284 PMCID: PMC6300132 SCOPUS ID: 2-s2.0-85053011653 09/22/2018       130 Citations
  • Small RNAs, but Sizable Itch: TRPA1 Activation by an Extracellular MicroRNA. (Sheahan TD, Hachisuka J, Ross SE) Neuron 2018 Aug 08;99(3):421-422 PMID: 30092208 SCOPUS ID: 2-s2.0-85050581354 08/10/2018       6 Citations
  • Angiotensin II Triggers Peripheral Macrophage-to-Sensory Neuron Redox Crosstalk to Elicit Pain. (Shepherd AJ, Copits BA, Mickle AD, Karlsson P, Kadunganattil S, Haroutounian S, Tadinada SM, de Kloet AD, Valtcheva MV, McIlvried LA, Sheahan TD, Jain S, Ray PR, Usachev YM, Dussor G, Krause EG, Price TJ, Gereau RW 4th, Mohapatra DP) J Neurosci 2018 Aug 08;38(32):7032-7057 PMID: 29976627 PMCID: PMC6083458 SCOPUS ID: 2-s2.0-85051586513 07/07/2018       105 Citations
  • Metabotropic Glutamate Receptor 2/3 (mGluR2/3) Activation Suppresses TRPV1 Sensitization in Mouse, But Not Human, Sensory Neurons. (Sheahan TD, Valtcheva MV, McIlvried LA, Pullen MY, Baranger DAA, Gereau RW 4th) eNeuro 2018;5(2) PMID: 29662945 PMCID: PMC5898698 SCOPUS ID: 2-s2.0-85046466108 04/18/2018       36 Citations
  • Inflammation and nerve injury minimally affect mouse voluntary behaviors proposed as indicators of pain. (Sheahan TD, Siuda ER, Bruchas MR, Shepherd AJ, Mohapatra DP, Gereau RW 4th, Golden JP) Neurobiol Pain 2017;2:1-12 PMID: 29075674 PMCID: PMC5653321 SCOPUS ID: 2-s2.0-85036565741 10/28/2017       65 Citations
  • Surgical extraction of human dorsal root ganglia from organ donors and preparation of primary sensory neuron cultures. (Valtcheva MV, Copits BA, Davidson S, Sheahan TD, Pullen MY, McCall JG, Dikranian K, Gereau RW 4th) Nat Protoc 2016 Oct;11(10):1877-88 PMID: 27606776 PMCID: PMC5082842 SCOPUS ID: 2-s2.0-84988624574 09/09/2016       87 Citations
  • Voluntary Exercise Training: Analysis of Mice in Uninjured, Inflammatory, and Nerve-Injured Pain States. (Sheahan TD, Copits BA, Golden JP, Gereau RW 4th) PLoS One 2015;10(7):e0133191 PMID: 26196858 PMCID: PMC4510282 SCOPUS ID: 2-s2.0-84941309531 07/22/2015       37 Citations
  • Last update: 07/07/2026