Medical College of Wisconsin
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William J. Peppard PharmD

William J. Peppard PharmD profile photo picture

Trauma/Surgical Critical Care Pharmacist

Institution: Froedtert Hospital
Department: Pharmacy


Research Experience

  • Analgesia
  • Clinical Pharmacy Information Systems
  • Conscious Sedation
  • Critical Care
  • Deep Sedation
  • Pharmacists
  • Pharmacy Service, Hospital
  • drug therapy
  • Leadership Positions

  • Director, Critical Care Pharmacy Residency
  • Publications (27)

  • Guidelines for the Management of Adult Acute and Acute-on-Chronic Liver Failure in the ICU: Cardiovascular, Endocrine, Hematologic, Pulmonary, and Renal Considerations. (Nanchal R, Subramanian R, Karvellas CJ, Hollenberg SM, Peppard WJ, Singbartl K, Truwit J, Al-Khafaji AH, Killian AJ, Alquraini M, Alshammari K, Alshamsi F, Belley-Cote E, Cartin-Ceba R, Dionne JC, Galusca DM, Huang DT, Hyzy RC, Junek M, Kandiah P, Kumar G, Morgan RL, Morris PE, Olson JC, Sieracki R, Steadman R, Taylor B, Alhazzani W) Crit Care Med 2020 Mar;48(3):e173-e191 PMID: 32058387 SCOPUS ID: 2-s2.0-85079359996 02/15/2020       3 Citations
  • Guidelines for the Management of Adult Acute and Acute-on-Chronic Liver Failure in the ICU: Cardiovascular, Endocrine, Hematologic, Pulmonary and Renal Considerations: Executive Summary. (Nanchal R, Subramanian R, Karvellas CJ, Hollenberg SM, Peppard WJ, Singbartl K, Truwit J, Al-Khafaji AH, Killian AJ, Alquraini M, Alshammari K, Alshamsi F, Belley-Cote E, Cartin-Ceba R, Dionne JC, Galusca DM, Huang DT, Hyzy RC, Junek M, Kandiah P, Kumar G, Morgan RL, Morris PE, Olson JC, Sieracki R, Steadman R, Taylor B, Alhazzani W) Crit Care Med 2020 Mar;48(3):415-419 PMID: 32058375 SCOPUS ID: 2-s2.0-85079360182 02/15/2020       2 Citations
  • Antibiotic Duration and Outcome Complications for Surgical Site Infection Prevention in Traumatic Mandible Fracture. (Zein Eddine SB, Cooper-Johnson K, Ericksen F, Brookes CC, Peppard WJ, Revolinski SL, Carver TW) J Surg Res 2020 03;247:524-529 PMID: 31668431 SCOPUS ID: 2-s2.0-85074440328 11/02/2019    
  • Phase 3 Pilot Randomized Controlled Trial Comparing Early Trophic Enteral Nutrition With "No Enteral Nutrition" in Mechanically Ventilated Patients With Septic Shock. (Patel JJ, Kozeniecki M, Peppard WJ, Peppard SR, Zellner-Jones S, Graf J, Szabo A, Heyland DK) JPEN J Parenter Enteral Nutr 2020 Jul;44(5):866-873 PMID: 31535394 SCOPUS ID: 2-s2.0-85073992718 09/20/2019       2 Citations
  • Ketamine infusion for pain control in elderly patients with multiple rib fractures: Results of a randomized controlled trial. (Kugler NW, Carver TW, Juul J, Peppard WJ, Boyle K, Drescher KM, Szabo A, Rein L, Somberg LB, Paul JS) J Trauma Acute Care Surg 2019 11;87(5):1181-1188 PMID: 31425468 SCOPUS ID: 2-s2.0-85074184716 08/20/2019    
  • Reply to Letter: Ketamine infusion for pain control in adult patients with multiple rib fractures. (Kugler NW, Juul J, Peppard WJ, Carver TW) J Trauma Acute Care Surg 2019 10;87(4):1001-1003 PMID: 31136526 SCOPUS ID: 2-s2.0-85072848763 05/29/2019    
  • Continuous Etomidate Infusion for the Management of Severe Cushing Syndrome: Validation of a Standard Protocol. (Carroll TB, Peppard WJ, Herrmann DJ, Javorsky BR, Wang TS, Patel H, Zarnecki K, Findling JW) J Endocr Soc 2019 Jan 01;3(1):1-12 PMID: 30560224 PMCID: PMC6291660 12/19/2018    
  • Current Practices of Intraventricular Antibiotic Therapy in the Treatment of Meningitis and Ventriculitis: Results from a Multicenter Retrospective Cohort Study. (Lewin JJ 3rd, Cook AM, Gonzales C, Merola D, Neyens R, Peppard WJ, Brophy GM, Kurczewski L, Giarratano M, Makii J, Rowe AS, Tesoro EP, Zaniewski A, Clark S, Ziai WC) Neurocrit Care 2019 06;30(3):609-616 PMID: 30446934 SCOPUS ID: 2-s2.0-85056659490 11/18/2018       3 Citations
  • Ketamine infusion for pain control in adult patients with multiple rib fractures: Results of a randomized control trial. (Carver TW, Kugler NW, Juul J, Peppard WJ, Drescher KM, Somberg LB, Szabo A, Yin Z, Paul JS) J Trauma Acute Care Surg 2019 02;86(2):181-188 PMID: 30376537 SCOPUS ID: 2-s2.0-85060819442 10/31/2018       8 Citations
  • Pharmacological considerations in acute and chronic liver disease (Peppard WJ, Killian AJ, Biesboer AN) Hepatic Critical Care 8 January 2018:211-232 SCOPUS ID: 2-s2.0-85054950262 01/08/2018    
  • Pharmacist involvement on a rapid response team. (Feih J, Peppard WJ, Katz M) Am J Health Syst Pharm 2017 Mar 01;74(5 Supplement 1):S10-S16 PMID: 28213382 SCOPUS ID: 2-s2.0-85032283255 02/19/2017       5 Citations
  • Association between Pre-Operative Cefazolin Dose and Surgical Site Infection in Obese Patients. (Peppard WJ, Eberle DG, Kugler NW, Mabrey DM, Weigelt JA) Surg Infect (Larchmt) 2017 May/Jun;18(4):485-490 PMID: 27906601 PMCID: PMC5466014 SCOPUS ID: 2-s2.0-85019715220 12/03/2016       12 Citations
  • New developments in the treatment of acute bacterial skin and skin structure infections: considerations for the effective use of dalbavancin. (Juul JJ, Mullins CF, Peppard WJ, Huang AM) Ther Clin Risk Manag 2016;12:225-32 PMID: 26937194 PMCID: PMC4762434 03/05/2016    
  • Implementation of Polymerase Chain Reaction to Rule Out Clostridium difficile Infection Is Associated With Reduced Empiric Antibiotic Duration of Therapy. (Peppard WJ, Ledeboer NA) Hosp Pharm 2014 Jul;49(7):639-43 PMID: 25477583 PMCID: PMC4252234 12/06/2014    
  • Early Trophic Enteral Nutrition Is Associated With Improved Outcomes in Mechanically Ventilated Patients With Septic Shock: A Retrospective Review. (Patel JJ, Kozeniecki M, Biesboer A, Peppard W, Ray AS, Thomas S, Jacobs ER, Nanchal R, Kumar G) J Intensive Care Med 2016 Aug;31(7):471-7 PMID: 25315218 SCOPUS ID: 2-s2.0-84978069680 10/16/2014       19 Citations
  • Photo quiz: a 5-year-old male with multiple pustules covering the entire scalp. Inflammatory Tinea Capitis. (Feih J, Ledeboer NA, Peppard WJ) J Clin Microbiol 2014 Apr;52(4):1027, 1312 PMID: 24619982 PMCID: PMC3993504 SCOPUS ID: 2-s2.0-84897149340 03/13/2014    
  • Phenytoin removal by continuous venovenous hemofiltration. (Oltrogge KM, Peppard WJ, Saleh M, Regner KR, Herrmann DJ) Ann Pharmacother 2013 Sep;47(9):1218-22 PMID: 24259740 SCOPUS ID: 2-s2.0-84884491746 11/22/2013       8 Citations
  • Optimizing drug therapy in the surgical intensive care unit. (Peppard WJ, Peppard SR, Somberg L) Surg Clin North Am 2012 Dec;92(6):1573-620 PMID: 23153885 SCOPUS ID: 2-s2.0-84869127744 11/17/2012       2 Citations
  • Safety and efficacy of prophylactic anticoagulation in patients with traumatic brain injury. (Scudday T, Brasel K, Webb T, Codner P, Somberg L, Weigelt J, Herrmann D, Peppard W) J Am Coll Surg 2011 Jul;213(1):148-53; discussion 153-4 PMID: 21459632 SCOPUS ID: 2-s2.0-79959503385 04/05/2011       63 Citations
  • Role of telavancin in treatment of skin and skin structure infections. (Bonkowski J, Daniels AR, Peppard WJ) Clin Cosmet Investig Dermatol 2010 Oct 07;3:127-33 PMID: 21437067 PMCID: PMC3047943 01/01/2010    
  • Evidence based approach to the treatment of community-associated methicillin-resistant Staphylococcus aureus (Peppard WJ, Daniels A, Fehrenbacher L, Winner J) Infection and Drug Resistance 2009;2(1):27-40 SCOPUS ID: 2-s2.0-77953384850 12/01/2009    
  • Evidence based approach to the treatment of community-associated methicillin-resistant Staphylococcus aureus. (Peppard WJ, Daniels A, Fehrenbacher L, Winner J) Infect Drug Resist 2009;2:27-40 PMID: 21694885 PMCID: PMC3108727 01/01/2009    
  • Linezolid for the treatment of drug-resistant infections. (Herrmann DJ, Peppard WJ, Ledeboer NA, Theesfeld ML, Weigelt JA, Buechel BJ) Expert Rev Anti Infect Ther 2008 Dec;6(6):825-48 PMID: 19053895 SCOPUS ID: 2-s2.0-59449100218 12/05/2008       23 Citations
  • Pharmacologic options for CNS infections caused by resistant Gram-positive organisms. (Peppard WJ, Johnston CJ, Urmanski AM) Expert Rev Anti Infect Ther 2008 Feb;6(1):83-99 PMID: 18251666 SCOPUS ID: 2-s2.0-40649123588 02/07/2008       12 Citations
  • Iclaprim, a diaminopyrimidine dihydrofolate reductase inhibitor for the potential treatment of antibiotic-resistant staphylococcal infections. (Peppard WJ, Schuenke CD) Curr Opin Investig Drugs 2008 Feb;9(2):210-25 PMID: 18246524 SCOPUS ID: 2-s2.0-38849190721 02/05/2008       26 Citations
  • Clostridium difficile enteritis: an early postoperative complication in inflammatory bowel disease patients after colectomy. (Lundeen SJ, Otterson MF, Binion DG, Carman ET, Peppard WJ) J Gastrointest Surg 2007 Feb;11(2):138-42 PMID: 17390162 SCOPUS ID: 2-s2.0-34548442485 03/29/2007       65 Citations
  • Role of linezolid in the treatment of complicated skin and soft tissue infections. (Peppard WJ, Weigelt JA) Expert Rev Anti Infect Ther 2006 Jun;4(3):357-66 PMID: 16771613 SCOPUS ID: 2-s2.0-33745214003 06/15/2006       20 Citations
  • Last update: 03/16/2020
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