Medical College of Wisconsin
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Yongwoo Seo MD

Yongwoo Seo MD profile photo picture

Assistant Professor

Institution: Medical College of Wisconsin
Department: Surgery
Division: Surgical Oncology

image of /images/ORCIDiD_icon16x16.png   https://orcid.org/0000-0001-6837-5018

Member of the Cancer Center


I am willing to collaborate on research projects.
I am willing to be a peer mentor.
I am willing to mentor a junior faculty member.

View Curriculum Vitae

Research Areas of Interest

  • Clinical Trial, Phase II
  • Clinical Trial, Phase III
  • Humans
  • Pancreatic Neoplasms
  • Receptors, Antigen, T-Cell
  • Robotic Surgical Procedures
  • T-Lymphocytes
  • Tumor Microenvironment

    • Clinical Expertise

  • Humans
  • Pancreatic Neoplasms
  • Surgical Oncology

    • Publications (34)

  • Cancer Testis Antigen Expression Correlates With Immune Activation and Survival in Small Bowel Neuroendocrine Tumors. (Ayabe RI, Seo YD, Melendez B, Fields BC, Diggs LP, Lazcano R, Singh BB, Wani K, Ingram D, Johnson S, Chelvanambi M, Hudgens C, Hernandez SD, Ajami NJ, Wargo JA, Lazar AJ, Knafl M, Woodman S, Halperin DM, Estrella JS, Maxwell JE) JCO Precis Oncol 2025 Jul;9:e2500107 PMID: 40638874 PMCID: PMC12463141 SCOPUS ID: 2-s2.0-105010777796 07/10/2025    
  • Defining the Role of Adjuvant Radiotherapy for Biliary Tract Cancers: A Site-Specific Propensity-Matched Analysis. (Seo YD, Acidi B, Newton A, Haddad A, Chiang YJ, Coelho R, Newhook TE, Tzeng CD, Chun YS, Ludmir EB, Koay EJ, Javle M, Vauthey JN, Cao HST) Cancers (Basel) 2025 Feb 02;17(3) PMID: 39941861 PMCID: PMC11815919 SCOPUS ID: 2-s2.0-85217538724 02/13/2025       1 Citation
  • Defining the Role of Adjuvant Radiotherapy for Biliary Tract Cancers: A Site-Specific Propensity-Matched Analysis (Seo YD, Acidi B, Newton A, Haddad A, Chiang YJ, Coelho R, Newhook TE, Tzeng CWD, Chun YS, Ludmir EB, Koay EJ, Javle M, Vauthey JN, Cao HST) Cancers February 2025;17(3) SCOPUS ID: 2-s2.0-85217538724 02/01/2025       1 Citation
  • The Landmark Series: The Future of Pancreatic Cancer Clinical Trials. (Seo YD, Katz MHG, Snyder RA) Ann Surg Oncol 2025 Apr;32(4):2777-2785 PMID: 39815074 SCOPUS ID: 2-s2.0-85217156020 01/16/2025       1 Citation
  • HIPEC for metastatic gastric cancer: Moving the needle towards 3-year survival (Bhutiani N, Seo YD, Robinson KA, White MG, Ikoma N, Mansfield PF, Li JJ, Murphy MB, Ajani JA, Badgwell BD) European Journal of Surgical Oncology January 2025;51(1) SCOPUS ID: 2-s2.0-85207889387 01/01/2025       2 Citations
  • HIPEC for metastatic gastric cancer: Moving the needle towards 3-year survival. (Bhutiani N, Seo YD, Robinson KA, White MG, Ikoma N, Mansfield PF, Li JJ, Murphy MB, Ajani JA, Badgwell BD) Eur J Surg Oncol 2025 Jan;51(1):108790 PMID: 39489042 PMCID: PMC12622865 SCOPUS ID: 2-s2.0-85207889387 11/04/2024       2 Citations
  • Current Status of Immunotherapy in Management of Small Bowel Neuroendocrine Tumors. (Fields BC, Ayabe RI, Seo YD, Maxwell JE, Halperin DM) Curr Oncol Rep 2024 Nov;26(11):1530-1542 PMID: 39466478 PMCID: PMC11776107 SCOPUS ID: 2-s2.0-85207815177 10/28/2024       1 Citation
  • Local Immunoradiotherapy in Patients With Metastatic Soft-Tissue Sarcoma-Reply. (Seo YD, Pollack SM) JAMA Oncol 2024 Jun 01;10(6):830-831 PMID: 38602667 SCOPUS ID: 2-s2.0-85190480277 04/11/2024    
  • Randomized Placebo-Controlled, Biomarker-Stratified Phase Ib Microbiome Modulation in Melanoma: Impact of Antibiotic Preconditioning on Microbiome and Immunity. (Glitza IC, Seo YD, Spencer CN, Wortman JR, Burton EM, Alayli FA, Loo CP, Gautam S, Damania A, Densmore J, Fairchild J, Cabanski CR, Wong MC, Peterson CB, Weiner B, Hicks N, Aunins J, McChalicher C, Walsh E, Tetzlaff MT, Hamid O, Ott PA, Boland GM, Sullivan RJ, Grossmann KF, Ajami NJ, LaVallee T, Henn MR, Tawbi HA, Wargo JA) Cancer Discov 2024 Jul 01;14(7):1161-1175 PMID: 38588588 PMCID: PMC11215408 SCOPUS ID: 2-s2.0-85197893321 04/08/2024       46 Citations
  • Intratumoral T-cell receptor repertoire composition predicts overall survival in patients with pancreatic ductal adenocarcinoma. (Pothuri VS, Hogg GD, Conant L, Borcherding N, James CA, Mudd J, Williams G, Seo YD, Hawkins WG, Pillarisetty VG, DeNardo DG, Fields RC) Oncoimmunology 2024;13(1):2320411 PMID: 38504847 PMCID: PMC10950267 SCOPUS ID: 2-s2.0-85188105419 03/20/2024       9 Citations
  • Modulating a prebiotic food source influences inflammation and immune-regulating gut microbes and metabolites: insights from the BE GONE trial. (Zhang X, Irajizad E, Hoffman KL, Fahrmann JF, Li F, Seo YD, Browman GJ, Dennison JB, Vykoukal J, Luna PN, Siu W, Wu R, Murage E, Ajami NJ, McQuade JL, Wargo JA, Long JP, Do KA, Lampe JW, Basen-Engquist KM, Okhuysen PC, Kopetz S, Hanash SM, Petrosino JF, Scheet P, Daniel CR) EBioMedicine 2023 Dec;98:104873 PMID: 38040541 PMCID: PMC10755114 SCOPUS ID: 2-s2.0-85179481195 12/02/2023       31 Citations
  • Toll-Like Receptor 4 Agonist Injection With Concurrent Radiotherapy in Patients With Metastatic Soft Tissue Sarcoma: A Phase 1 Nonrandomized Controlled Trial. (Seo YD, Lu H, Black G, Smythe K, Yu Y, Hsu C, Ng J, Hermida de Viveiros P, Warren EH, Schroeder BA, O'Malley RB, Cranmer LD, Loggers ET, Wagner MJ, Bonham L, Pillarisetty VG, Kane G, Berglund P, Hsu FJ, Mi X, Alexiev BA, Pierce RH, Riddell SR, Jones RL, Ter Meulen J, Kim EY, Pollack SM) JAMA Oncol 2023 Dec 01;9(12):1660-1668 PMID: 37824131 PMCID: PMC10570919 SCOPUS ID: 2-s2.0-85179665501 10/12/2023       23 Citations
  • Using gut microorganisms to treat cancer. (Seo YD, Ajami N, Wargo JA) Nat Med 2023 Aug;29(8):1910-1911 PMID: 37420098 SCOPUS ID: 2-s2.0-85164488430 07/08/2023       3 Citations
  • Efficacy of immune checkpoint inhibitors for the treatment of advanced melanoma in patients with concomitant chronic lymphocytic leukemia. (Cass SH, Tobin JWD, Seo YD, Gener-Ricos G, Keung EZ, Burton EM, Davies MA, McQuade JL, Lazar AJ, Mason R, Millward M, Sandhu S, Khoo C, Warburton L, Guerra V, Haydon A, Dearden H, Menzies AM, Carlino MS, Smith JL, Mollee P, Burgess M, Mapp S, Keane C, Atkinson V, Parikh SA, Markovic SN, Ding W, Call TG, Hampel PJ, Long GV, Wargo JA, Ferrajoli A) Ann Oncol 2023 Sep;34(9):796-805 PMID: 37414216 PMCID: PMC11289780 SCOPUS ID: 2-s2.0-85167984912 07/07/2023       9 Citations
  • From bugs to drugs: Bacterial 3-IAA enhances efficacy of chemotherapy in pancreatic cancer. (Seo YD, Wargo JA) Cell Rep Med 2023 May 16;4(5):101039 PMID: 37196631 PMCID: PMC10213830 SCOPUS ID: 2-s2.0-85159151289 05/18/2023       9 Citations
  • Monitoring and Modulating Diet and Gut Microbes to Enhance Response and Reduce Toxicity to Cancer Treatment. (Knisely A, Seo YD, Wargo JA, Chelvanambi M) Cancers (Basel) 2023 Jan 27;15(3) PMID: 36765735 PMCID: PMC9913233 SCOPUS ID: 2-s2.0-85147867216 02/12/2023       17 Citations
  • Quality of superior mesenteric and hepatic artery dissection in robotic pancreatoduodenectomy for pancreatic cancer. (Ikoma N, Seo YD, Newhook TE, Maxwell JE, Kim MP, Tran Cao HS, Tzeng CD, Chun YS, Lee JE, Vauthey JN, Katz MHG) J Hepatobiliary Pancreat Sci 2023 Jan;30(1):e1-e2 PMID: 35950790 SCOPUS ID: 2-s2.0-85135822625 08/12/2022       4 Citations
  • Blockade of interleukin 10 potentiates antitumour immune function in human colorectal cancer liver metastases. (Sullivan KM, Jiang X, Guha P, Lausted C, Carter JA, Hsu C, Labadie KP, Kohli K, Kenerson HL, Daniel SK, Yan X, Meng C, Abbasi A, Chan M, Seo YD, Park JO, Crispe IN, Yeung RS, Kim TS, Gujral TS, Tian Q, Katz SC, Pillarisetty VG) Gut 2023 Feb;72(2):325-337 PMID: 35705369 PMCID: PMC9872249 SCOPUS ID: 2-s2.0-85132593579 06/16/2022       107 Citations
  • Preoperative therapy for pancreatic adenocarcinoma-precision beyond anatomy. (Seo YD, Katz MHG) Cancer 2022 Aug 15;128(16):3041-3056 PMID: 35679197 SCOPUS ID: 2-s2.0-85131541270 06/10/2022       26 Citations
  • Neoadjuvant Therapy Induces a Potent Immune Response to Sarcoma, Dominated by Myeloid and B Cells. (Goff PH, Riolobos L, LaFleur BJ, Spraker MB, Seo YD, Smythe KS, Campbell JS, Pierce RH, Zhang Y, He Q, Kim EY, Schaub SK, Kane GM, Mantilla JG, Chen EY, Ricciotti R, Thompson MJ, Cranmer LD, Wagner MJ, Loggers ET, Jones RL, Murphy E, Blumenschein WM, McClanahan TK, Earls J, Flanagan KC, LaFranzo NA, Kim TS, Pollack SM) Clin Cancer Res 2022 Apr 14;28(8):1701-1711 PMID: 35115306 PMCID: PMC9953754 SCOPUS ID: 2-s2.0-85128301568 02/05/2022       32 Citations
  • IWATE criteria are associated with perioperative outcomes in robotic hepatectomy: a retrospective review of 225 resections. (Labadie KP, Droullard DJ, Lois AW, Daniel SK, McNevin KE, Gonzalez JV, Seo YD, Sullivan KM, Bilodeau KS, Dickerson LK, Utria AF, Calhoun J, Pillarisetty VG, Sham JG, Yeung RS, Park JO) Surg Endosc 2022 Feb;36(2):889-895 PMID: 33608766 PMCID: PMC8758630 SCOPUS ID: 2-s2.0-85101209045 02/21/2021       31 Citations
  • Tumor slice culture as a biologic surrogate of human cancer. (Kenerson HL, Sullivan KM, Seo YD, Stadeli KM, Ussakli C, Yan X, Lausted C, Pillarisetty VG, Park JO, Riehle KJ, Yeh M, Tian Q, Yeung RS) Ann Transl Med 2020 Feb;8(4):114 PMID: 32175407 PMCID: PMC7049013 03/17/2020    
  • The CXCL12-CXCR4/CXCR7 axis as a mechanism of immune resistance in gastrointestinal malignancies. (Daniel SK, Seo YD, Pillarisetty VG) Semin Cancer Biol 2020 Oct;65:176-188 PMID: 31874281 SCOPUS ID: 2-s2.0-85077396109 12/25/2019       189 Citations
  • Yttrium-90-Labeled Anti-Glypican 3 Radioimmunotherapy Halts Tumor Growth in an Orthotopic Xenograft Model of Hepatocellular Carcinoma. (Ludwig AD, Labadie KP, Seo YD, Hamlin DK, Nguyen HM, Mahadev VM, Yeung RS, Wilbur DS, Park JO) J Oncol 2019;2019:4564707 PMID: 31636665 PMCID: PMC6766125 SCOPUS ID: 2-s2.0-85072821683 10/23/2019       10 Citations
  • Mobilization of CD8+ T Cells via CXCR4 Blockade Facilitates PD-1 Checkpoint Therapy in Human Pancreatic Cancer. (Seo YD, Jiang X, Sullivan KM, Jalikis FG, Smythe KS, Abbasi A, Vignali M, Park JO, Daniel SK, Pollack SM, Kim TS, Yeung R, Crispe IN, Pierce RH, Robins H, Pillarisetty VG) Clin Cancer Res 2019 Jul 01;25(13):3934-3945 PMID: 30940657 PMCID: PMC6606359 SCOPUS ID: 2-s2.0-85068312858 04/04/2019       191 Citations
  • Establishment of Slice Cultures as a Tool to Study the Cancer Immune Microenvironment. (Jiang X, Seo YD, Sullivan KM, Pillarisetty VG) Methods Mol Biol 2019;1884:283-295 PMID: 30465211 SCOPUS ID: 2-s2.0-85056913884 11/23/2018       31 Citations
  • Enhanced Recovery via Peripheral Nerve Block for Open Hepatectomy. (Thornblade LW, Seo YD, Kwan T, Cardoso JH, Pan E, Dembo G, Yeung RSW, Park JO) J Gastrointest Surg 2018 Jun;22(6):981-988 PMID: 29404987 PMCID: PMC5966330 SCOPUS ID: 2-s2.0-85045155336 02/07/2018       21 Citations
  • Long-lived pancreatic ductal adenocarcinoma slice cultures enable precise study of the immune microenvironment. (Jiang X, Seo YD, Chang JH, Coveler A, Nigjeh EN, Pan S, Jalikis F, Yeung RS, Crispe IN, Pillarisetty VG) Oncoimmunology 2017;6(7):e1333210 PMID: 28811976 PMCID: PMC5543820 SCOPUS ID: 2-s2.0-85023177118 08/16/2017       76 Citations
  • T-cell infiltration and clonality correlate with programmed cell death protein 1 and programmed death-ligand 1 expression in patients with soft tissue sarcomas. (Pollack SM, He Q, Yearley JH, Emerson R, Vignali M, Zhang Y, Redman MW, Baker KK, Cooper S, Donahue B, Loggers ET, Cranmer LD, Spraker MB, Seo YD, Pillarisetty VG, Ricciotti RW, Hoch BL, McClanahan TK, Murphy E, Blumenschein WM, Townson SM, Benzeno S, Riddell SR, Jones RL) Cancer 2017 Sep 01;123(17):3291-3304 PMID: 28463396 PMCID: PMC5568958 SCOPUS ID: 2-s2.0-85018743172 05/04/2017       228 Citations
  • T-cell programming in pancreatic adenocarcinoma: a review. (Seo YD, Pillarisetty VG) Cancer Gene Ther 2017 Mar;24(3):106-113 PMID: 27910859 SCOPUS ID: 2-s2.0-85001022181 12/03/2016       46 Citations
  • Efficacy and cost of robotic hepatectomy: is the robot cost-prohibitive? (Sham JG, Richards MK, Seo YD, Pillarisetty VG, Yeung RS, Park JO) J Robot Surg 2016 Dec;10(4):307-313 PMID: 27153838 SCOPUS ID: 2-s2.0-84966318745 05/08/2016       80 Citations
  • What is the best immunosuppressant combination in terms of antitumor effect in hepatocellular carcinoma? (Lee KW, Seo YD, Oh SC, Suh SW, Jeong J, Kim H, Yi NJ, Suh KS) Hepatol Res 2016 May;46(6):593-600 PMID: 26348114 SCOPUS ID: 2-s2.0-84969170514 09/09/2015       9 Citations
  • Emergent Esophagectomy for Esophageal Perforations: A Safe Option. (Seo YD, Lin J, Chang AC, Orringer MB, Lynch WR, Reddy RM) Ann Thorac Surg 2015 Sep;100(3):905-9 PMID: 26188974 SCOPUS ID: 2-s2.0-84940723040 07/21/2015       22 Citations
  • Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice. (Mukherjee S, Raje N, Schoonmaker JA, Liu JC, Hideshima T, Wein MN, Jones DC, Vallet S, Bouxsein ML, Pozzi S, Chhetri S, Seo YD, Aronson JP, Patel C, Fulciniti M, Purton LE, Glimcher LH, Lian JB, Stein G, Anderson KC, Scadden DT) J Clin Invest 2008 Feb;118(2):491-504 PMID: 18219387 PMCID: PMC2213372 SCOPUS ID: 2-s2.0-38849130851 01/26/2008       224 Citations
    • Last update: 10/06/2025