Medical College of Wisconsin
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Yunguang Sun MD, PhD

Yunguang Sun MD, PhD

Assistant Professor

Institution: Medical College of Wisconsin
Department: Pathology
Division: Administration

Member of the Cancer Center


  • SmgGDS is a transient nucleolar protein that protects cells from nucleolar stress and promotes the cell cycle by regulating DREAM complex gene expression. (Gonyo P, Bergom C, Brandt AC, Tsaih SW, Sun Y, Bigley TM, Lorimer EL, Terhune SS, Rui H, Flister MJ, Long RM, Williams CL) Oncogene 2017 Aug 14 PMID: 28806394 08/15/2017
  • IGFBP3 Modulates Lung Tumorigenesis and Cell Growth through IGF1 Signaling. (Wang YA, Sun Y, Palmer J, Solomides C, Huang LC, Shyr Y, Dicker AP, Lu B) Mol Cancer Res 2017 Jul;15(7):896-904 PMID: 28330997 03/24/2017
  • Nitrilase 1 modulates lung tumor progression in vitro and in vivo. (Wang YA, Sun Y, Le Blanc JM, Solomides C, Zhan T, Lu B) Oncotarget 2016 Apr 19;7(16):21381-92 PMID: 26967383 PMCID: PMC5008292 03/12/2016
  • Debio 1143, an antagonist of multiple inhibitor-of-apoptosis proteins, activates apoptosis and enhances radiosensitization of non-small cell lung cancer cells in vitro. (Liu N, Tao Z, Blanc JM, Zaorsky NG, Sun Y, Vuagniaux G, Dicker AP, Lu B) Am J Cancer Res 2014;4(6):943-51 PMID: 25520882 PMCID: PMC4266726 12/19/2014
  • Stable and efficient transfection of siRNA for mutated KRAS silencing using novel hybrid nanoparticles. (Lakshmikuttyamma A, Sun Y, Lu B, Undieh AS, Shoyele SA) Mol Pharm 2014 Dec 01;11(12):4415-24 PMID: 25340957 10/24/2014
  • Assessment of M867, a selective caspase-3 inhibitor, in an orthotopic mouse model for non-small cell lung carcinoma. (Li B, Blanc JM, Sun Y, Yang L, Zaorsky NG, Giacalone NJ, Torossian A, Lu B) Am J Cancer Res 2014;4(2):161-71 PMID: 24660105 PMCID: PMC3960453 03/25/2014
  • A novel radiation-induced p53 mutation is not implicated in radiation resistance via a dominant-negative effect. (Sun Y, Myers CJ, Dicker AP, Lu B) PLoS One 2014;9(2):e87492 PMID: 24558369 PMCID: PMC3928108 02/22/2014
  • Identification of a KRAS mutation in a patient with non-small cell lung cancer treated with chemoradiotherapy and panitumumab. (Zaorsky NG, Sun Y, Wang Z, Palmer J, Fortina PM, Solomides C, Werner-Wasik M, Dicker AP, Axelrod R, Campling B, Evans N 3rd, Cowan S, Lu B) Cancer Biol Ther 2013 Oct 01;14(10):883-7 PMID: 23917487 PMCID: PMC3926884 08/07/2013
  • ALK inhibitor PF02341066 (crizotinib) increases sensitivity to radiation in non-small cell lung cancer expressing EML4-ALK. (Sun Y, Nowak KA, Zaorsky NG, Winchester CL, Dalal K, Giacalone NJ, Liu N, Werner-Wasik M, Wasik MA, Dicker AP, Lu B) Mol Cancer Ther 2013 May;12(5):696-704 PMID: 23443800 PMCID: PMC3651772 02/28/2013
  • PA1 protein, a new competitive decelerator acting at more than one step to impede glucocorticoid receptor-mediated transactivation. (Zhang Z, Sun Y, Cho YW, Chow CC, Simons SS Jr) J Biol Chem 2013 Jan 04;288(1):42-58 PMID: 23161582 PMCID: PMC3537039 11/20/2012
  • Higher levels of c-Met expression and phosphorylation identify cell lines with increased sensitivity to AMG-458, a novel selective c-Met inhibitor with radiosensitizing effects. (Li B, Torossian A, Sun Y, Du R, Dicker AP, Lu B) Int J Radiat Oncol Biol Phys 2012 Nov 15;84(4):e525-31 PMID: 22836051 07/28/2012
  • Role of insulin-like growth factor-1 signaling pathway in cisplatin-resistant lung cancer cells. (Sun Y, Zheng S, Torossian A, Speirs CK, Schleicher S, Giacalone NJ, Carbone DP, Zhao Z, Lu B) Int J Radiat Oncol Biol Phys 2012 Mar 01;82(3):e563-72 PMID: 22197230 PMCID: PMC3271860 12/27/2011
  • BV6, an IAP antagonist, activates apoptosis and enhances radiosensitization of non-small cell lung carcinoma in vitro. (Li W, Li B, Giacalone NJ, Torossian A, Sun Y, Niu K, Lin-Tsai O, Lu B) J Thorac Oncol 2011 Nov;6(11):1801-9 PMID: 21760551 PMCID: PMC3196825 07/16/2011
  • Inhibition of JAK2 signaling by TG101209 enhances radiotherapy in lung cancer models. (Sun Y, Moretti L, Giacalone NJ, Schleicher S, Speirs CK, Carbone DP, Lu B) J Thorac Oncol 2011 Apr;6(4):699-706 PMID: 21325979 PMCID: PMC3104103 02/18/2011
  • Enhanced radiosensitivity of androgen-resistant prostate cancer: AZD1152-mediated Aurora kinase B inhibition. (Niermann KJ, Moretti L, Giacalone NJ, Sun Y, Schleicher SM, Kopsombut P, Mitchell LR, Kim KW, Lu B) Radiat Res 2011 Apr;175(4):444-51 PMID: 21222513 PMCID: PMC3133747 01/13/2011
  • Terameprocol (tetra-O-methyl nordihydroguaiaretic acid), an inhibitor of Sp1-mediated survivin transcription, induces radiosensitization in non-small cell lung carcinoma. (Sun Y, Giacalone NJ, Lu B) J Thorac Oncol 2011 Jan;6(1):8-14 PMID: 21107289 PMCID: PMC3010256 11/26/2010
  • Targeting the mechanisms of resistance to chemotherapy and radiotherapy with the cancer stem cell hypothesis. (Morrison R, Schleicher SM, Sun Y, Niermann KJ, Kim S, Spratt DE, Chung CH, Lu B) J Oncol 2011;2011:941876 PMID: 20981352 PMCID: PMC2958340 10/29/2010
  • Modulation of transcription parameters in glucocorticoid receptor-mediated repression. (Sun Y, Tao YG, Kagan BL, He Y, Simons SS Jr) Mol Cell Endocrinol 2008 Nov 25;295(1-2):59-69 PMID: 18583028 PMCID: PMC2662735 06/28/2008
  • Effects of acetylation, polymerase phosphorylation, and DNA unwinding in glucocorticoid receptor transactivation. (Kim Y, Sun Y, Chow C, Pommier YG, Simons SS Jr) J Steroid Biochem Mol Biol 2006 Jul;100(1-3):3-17 PMID: 16723222 05/26/2006
  • Memantine alleviates toxicity induced by dichlorvos in rats. (Zhou Z, Dai X, Gu X, Sun Y, Zheng G, Zheng J) J Occup Health 2005 Mar;47(2):96-101 PMID: 15824473 04/13/2005
  • [The acute effects of dimethoate on the muscarinic-receptors of rat brains and the relationship between muscarinic-receptors and cholinesterase]. (Sun Y, Zhou Z, Hu Y, Chen J, Jin T) Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2002 Aug;20(4):293-5 PMID: 14694657 12/26/2003
  • Last update: 09/20/2017
    jenkins-FCD Prod-130 96200611f8481f0aa4f84230b11dd74d063847a3