Artifactual reduction in bone density as a result of technetium-99m MDP for bone scanning: report of two cases. J Clin Densitom 2004;7(4):457-8
Date
12/25/2004Pubmed ID
15618608DOI
10.1385/jcd:7:4:457Scopus ID
2-s2.0-12244277428 (requires institutional sign-in at Scopus site) 11 CitationsAbstract
We present two patients in whom marked changes in dual-energy X-ray absorptiometry (DXA)-measured bone mineral density were found to be the result of prior administration of technetium-99m methylene diphosphonate (MDP) for bone scanning. In patient 1, an artifactual 50% decrease in lumbar spine and 19% decrease in left total hip bone density over a 14-mo period was the result of technetium-99m injection 3 h before the second bone density measurement. In patient 2, a dramatic increase in bone density at 6 mo was the result of artifactual reduction in bone density on the baseline study as a result of technetium-99m injection 2 h earlier. Clinicians and technologists should be aware that technetium-99m used for bone scanning could cause artifactual reduction in DXA-measured bone mineral density.
Author List
Chan PS, Binkley NC, Lalande BM, Young S, Shaker JLAuthors
Beth M. Lalande MD Associate Professor in the Medicine department at Medical College of WisconsinJoseph L. Shaker MD Professor in the Medicine department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
Absorptiometry, PhotonAdult
Artifacts
Bone Density
Bone and Bones
Female
Follow-Up Studies
Hip Joint
Humans
Lumbar Vertebrae
Middle Aged
Radionuclide Imaging
Radiopharmaceuticals
Technetium Tc 99m Medronate
