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Neonatal diuretic therapy: furosemide, thiazides, and spironolactone. Clin Perinatol 2012 Mar;39(1):209-20

Date

02/22/2012

Pubmed ID

22341547

DOI

10.1016/j.clp.2011.12.007

Scopus ID

2-s2.0-84857085333   19 Citations

Abstract

Diuretics are commonly used to treat infants with oxygen-dependent chronic lung disease. However, there are limited data suggesting a beneficial effect of long-term diuretic therapy on pulmonary function or clinical outcome in this population. Furthermore, data available for review were primarily obtained before the widespread use of antenatal steroids or surfactant replacement therapy, before recognition of the new bronchopulmonary dysplasia. If used in this population, limitations of diuretic therapy as well as significant side effects need to be understood and a rationale approach to clinical use developed on a patient-centered basis.

Author List

Segar JL

Author

Jeffrey L. Segar MD Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Bronchopulmonary Dysplasia
Diuretics
Ductus Arteriosus, Patent
Furosemide
Humans
Infant, Newborn
Infant, Newborn, Diseases
Infant, Premature
Infant, Premature, Diseases
Kidney
Kidney Function Tests
Lung Diseases
Respiratory Function Tests
Spironolactone
Thiazides
jenkins-FCD Prod-410 e9586552fe7f53c71f7923aa6e27aeabbd3c2473