The effect of inhaled nitric oxide therapy on bleeding time and platelet aggregation in neonates. J Pediatr 1998 Apr;132(4):731-4
Date
05/15/1998Pubmed ID
9580780DOI
10.1016/s0022-3476(98)70370-1Scopus ID
2-s2.0-0031925241 (requires institutional sign-in at Scopus site) 89 CitationsAbstract
The effect of inhaled nitric oxide (iNO) on bleeding time and platelet aggregation was studied in nine newborn infants with resolving pulmonary hypertension. Infants treated with iNO at 40 ppm for 30 minutes had bleeding times that were nearly twofold longer than those obtained 24 hours after iNO was discontinued. iNO had no effect on in vitro platelet aggregation studies.
Author List
George TN, Johnson KJ, Bates JN, Segar JLAuthor
Jeffrey L. Segar MD Professor in the Pediatrics department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Administration, InhalationBleeding Time
Humans
Infant, Newborn
Nitric Oxide
Persistent Fetal Circulation Syndrome
Platelet Aggregation