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Independent factors associated with major depressive disorder in a national sample of individuals with diabetes. Diabetes Care 2003 Jan;26(1):104-11

Date

12/28/2002

Pubmed ID

12502665

DOI

10.2337/diacare.26.1.104

Scopus ID

2-s2.0-0038568093 (requires institutional sign-in at Scopus site)   182 Citations

Abstract

OBJECTIVE: To determine whether perceived poor physical health, duration of diabetes, and smoking are associated with major depressive disorder in a national sample of individuals with diabetes.

RESEARCH DESIGN AND METHODS: Data on 1,810 individuals with diabetes from the 1999 National Health Interview Survey (NHIS) were analyzed. The Composite International Diagnostic Interview (CIDI) Short-Form (CIDI-SF) developed by the World Health Organization was used to identify individuals with major depressive disorder. Multiple logistic regression was used to determine whether perceived poor physical health, duration of diabetes, and smoking were associated with major depressive disorder. The model controlled for age, sex, race/ethnicity, education, income, employment, marital status, and health status. Other control variables included BMI, smoking, duration of diabetes, presence or absence of major complications, and type of treatment for diabetes. SUDAAN software was used for statistical analyses to account for the complex sampling design of NHIS.

RESULTS: Independent factors associated with major depressive disorder were age <64 years, female sex, at least high school education, income <124% of federal poverty level, perceived worsening of health status, and smoking.

CONCLUSIONS: In addition to other psychosocial factors such as younger age, female sex, lower income, at least high school education, and smoking, perceptions about the effect of diabetes on overall health seems to play an important role in the etiology of depression.

Author List

Egede LE, Zheng D

Author

Leonard E. Egede MD Center Director, Chief, Professor in the Medicine department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adolescent
Adult
Aged
Depressive Disorder, Major
Diabetes Mellitus, Type 1
Diabetes Mellitus, Type 2
Female
Health Status
Humans
Male
Middle Aged
Multivariate Analysis
Psychology
Risk Factors
Smoking
Social Class