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Comparison between MP-1 and Humphrey visual field defects in glaucoma and retinitis pigmentosa. Optom Vis Sci 2012 Jul;89(7):1050-8

Date

06/27/2012

Pubmed ID

22733099

Pubmed Central ID

PMC3498616

DOI

10.1097/OPX.0b013e31825da18c

Abstract

PURPOSE: To compare MP-1 microperimeter and Humphrey Field Analyzer (HFA) defects, in patients with retinitis pigmentosa (RP), a disease primarily affecting the photoreceptors, and in patients with glaucoma, a disease primarily affecting postreceptoral ganglion cells, and to analyze the similarities and differences between the results.

METHODS: Eleven patients (11 eyes) with RP and 10 patients (10 eyes) with primary open-angle glaucoma (OAG) underwent MP-1 and HFA visual field testing (10-2 pattern). All tested eyes had defects encroaching within 10° of fixation. MP-1 total deviation (TD) probability defects, derived from a previously collected normative database of 50 subjects, were compared to HFA TD defects and to the local defect map of the MP-1. Test duration was compared between instruments.

RESULTS: In RP patients, MP-1 scotomata were deeper and wider than HFA defects; however in OAG, the opposite was observed. Examination duration in both patient groups was 12 to 14 min for the MP-1 and 6 min for the HFA. The MP-1 local defect map tended to overestimate defects compared to the MP-1 TD analysis.

CONCLUSIONS: The differences in results between the MP-1 and HFA for the two groups of patients with RP and OAG can be attributed to the different adaptation levels and to the dynamic range of test lights available for the two instruments. The clinician should also be aware of the possible consequences of the differences in the method of derivation of normative data for the two instruments, as this may affect the interpretation of visual field results.

Author List

Acton JH, Smith RT, Greenberg JP, Greenstein VC

Author

Jonathan P. Greenberg MD Instructor in the Ophthalmology and Visual Sciences department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adolescent
Adult
Child
Diagnosis, Differential
Equipment Design
Female
Glaucoma, Open-Angle
Humans
Male
Middle Aged
Reproducibility of Results
Retinitis Pigmentosa
Scotoma
Visual Field Tests
Visual Fields
Young Adult
jenkins-FCD Prod-409 d1e206b0be345926047b0d9c353c78a4cce4058b