Osteoporosis associated with excess glucocorticoids. Endocrinol Metab Clin North Am 2005 Jun;34(2):341-56, viii-ix
Date
04/27/2005Pubmed ID
15850846DOI
10.1016/j.ecl.2005.01.014Scopus ID
2-s2.0-18044398760 (requires institutional sign-in at Scopus site) 85 CitationsAbstract
Excess glucocorticoids, whether endogenous or exogenous, can cause osteoporosis and fractures. Even low doses of oral glucocorticoids and mild endogenous hypercortisolism may be associated with bone loss. Patients treated with glucocorticoids, however, often are not evaluated and treated for this problem. Patients on chronic glucocorticoids or initiating these drugs should have their bone density measured and appropriate laboratory studies. They should be treated with adequate calcium and vitamin D, and antiresorptive therapy (particularly bisphosphonates) should be considered.
Author List
Shaker JL, Lukert BPAuthor
Joseph L. Shaker MD Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
GlucocorticoidsHumans
Osteoporosis
Pituitary ACTH Hypersecretion
