Expansion of the Gene Ontology knowledgebase and resources. Nucleic Acids Res 2017 Jan 04;45(D1):D331-D338
Date
12/03/2016Pubmed ID
27899567Pubmed Central ID
PMC5210579DOI
10.1093/nar/gkw1108Scopus ID
2-s2.0-85016166168 (requires institutional sign-in at Scopus site) 1337 CitationsAbstract
The Gene Ontology (GO) is a comprehensive resource of computable knowledge regarding the functions of genes and gene products. As such, it is extensively used by the biomedical research community for the analysis of -omics and related data. Our continued focus is on improving the quality and utility of the GO resources, and we welcome and encourage input from researchers in all areas of biology. In this update, we summarize the current contents of the GO knowledgebase, and present several new features and improvements that have been made to the ontology, the annotations and the tools. Among the highlights are 1) developments that facilitate access to, and application of, the GO knowledgebase, and 2) extensions to the resource as well as increasing support for descriptions of causal models of biological systems and network biology. To learn more, visit http://geneontology.org/.
Author List
The Gene Ontology ConsortiumAuthors
Melinda R. Dwinell PhD Professor in the Physiology department at Medical College of WisconsinStanley J. Laulederkind Research Scientist II in the Physiology department at Medical College of Wisconsin
Shur-Jen Wang Research Scientist II in the Physiology department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
Computational BiologyDatabases, Genetic
Gene Ontology
Genomics
Molecular Sequence Annotation
Phylogeny
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