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Measurement of regional tissue bed venous weighted oximetric trends during exercise by near infrared spectroscopy. Pediatr Cardiol 2009 May;30(4):465-71

Date

02/20/2009

Pubmed ID

19225827

DOI

10.1007/s00246-009-9393-6

Scopus ID

2-s2.0-67349247662 (requires institutional sign-in at Scopus site)   14 Citations

Abstract

BACKGROUND: Cardiopulmonary exercise testing (CPET) is limited to children able to tolerate the equipment. Modification of instrumentation to reduce invasiveness will open CPET to a wider population. Near Infrared Spectroscopy (NIRS) devices measure regional oxyhemoglobin saturation (rSO2). We aim to predict anaerobic threshold (AT) during CPET using multiorgan NIRS monitoring.

METHODS AND RESULTS: Nineteen subjects were recruited. NIRS probes were placed on the forehead, para vertebral space, vastus lateralis, and deltoid muscle (rSO2 C, rSO2 R, rSO2 L and rSO2 A). rSO2 was recorded at six second intervals at rest, exercise, and through a five minute recovery period. The AT was computed using the v-slope method. AT was also predicted using NIRS data by identifying the inflection point of the rSO2 trends for all the four sites. AT can be estimated by the point of slope change of rSO2 R, rSO2 C and the four-site composite measure.

CONCLUSIONS: Multisite NIRS monitoring of visceral organs is a potential predictor of AT. This allows for monitoring in all forms of exercise over a wide age range.

Author List

Rao RP, Danduran MJ, Frommelt PC, Ghanayem NS, Berger S, Simpson PM, Yan K, Hoffman GM

Authors

Peter C. Frommelt MD Adjunct Professor in the Pediatrics department at Medical College of Wisconsin
George M. Hoffman MD Chief, Professor in the Anesthesiology department at Medical College of Wisconsin
Pippa M. Simpson PhD Adjunct Professor in the Pediatrics department at Medical College of Wisconsin
Ke Yan PhD Associate Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adolescent
Adult
Anaerobic Threshold
Child
Exercise Test
Female
Humans
Male
Oximetry
Oxygen
Oxyhemoglobins
Pilot Projects
Spectrophotometry, Infrared