Thyroid cancer in young adults. Semin Oncol 2009 Jun;36(3):258-74
Date
05/23/2009Pubmed ID
19460583DOI
10.1053/j.seminoncol.2009.03.009Scopus ID
2-s2.0-65549161768 (requires institutional sign-in at Scopus site) 17 CitationsAbstract
The incidence of thyroid cancer in young adults is rising. Differentiated carcinoma (ie, papillary, follicular, and their variants) and medullary thyroid carcinoma (MTC) represent the two most common subtypes, with differing etiologies, prognoses, and management strategies. Ultrasound (US)-guided fine needle aspiration (FNA) is the best initial test for evaluating a nodule or mass suspicious for malignancy. Tumor histology, in addition to radiographic findings and clinical presentation, guides surgical management, the need for adjuvant therapies, and the optimal approach to long-term follow-up. Radioactive iodine (RAI) is used to reduce recurrence and improve survival for differentiated thyroid carcinomas (DTCs). Emerging systemic therapies provide options for patients with progressive metastatic MTC or radio-resistant DTC. Overall, the prognosis for the most common thyroid malignancy, papillary thyroid carcinoma (PTC), is excellent. The treatment of young adult thyroid cancer patients occurs optimally as part of a multidisciplinary coordination of care.
Author List
Ying AK, Huh W, Bottomley S, Evans DB, Waguespack SGAuthor
Douglas B. Evans MD Chair, Professor in the Surgery department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultAge Factors
Carcinoma, Medullary
Female
Humans
Pregnancy
Pregnancy Complications, Neoplastic
Thyroid Neoplasms
Treatment Outcome