Medical College of Wisconsin
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The hair collar sign: marker for cranial dysraphism. Pediatrics 1995 Aug;96(2 Pt 1):309-13 PMID: 7630690

Pubmed ID

7630690

Abstract

OBJECTIVE: To call attention to a cutaneous marker for neural tube closure defects of the scalp, the "hair collar" sign. This finding consists of a ring of long, dark, coarse hair surrounding a midline scalp nodule.

METHODS AND RESULTS: Four children with small congenital scalp nodules and the hair collar sign were studied from the standpoint of clinical findings, radiologic scans, and histology of the excised nodules. All four had an overlying vascular stain in addition to the hair collar. Patients 1 and 2 were found to have encephaloceles, and one had heterotopic brain tissue. The fourth family refused surgery, but the clinical and radiologic findings were consistent with a diagnosis of atretic encephaloceles. One infant had agenesis of the corpus callosum and a Dandy-Walker malformation as associated findings.

CONCLUSIONS: The "hair collar" sign should alert the pediatrician to the possibility of ectopic neural tissue in the scalp and/or underlying central nervous system malformations.

Author List

Drolet BA, Clowry L Jr, McTigue MK, Esterly NB



Scopus

2-s2.0-0029123028   55 Citations

MESH terms used to index this publication - Major topics in bold

Agenesis of Corpus Callosum
Brain
Choristoma
Corpus Callosum
Dandy-Walker Syndrome
Encephalocele
Hair
Hamartoma
Humans
Infant
Magnetic Resonance Imaging
Male
Membrane Glycoproteins
Meninges
Mucin-1
Mucins
Neural Tube Defects
S100 Proteins
Scalp
Scalp Dermatoses
Tomography, X-Ray Computed
Vimentin
jenkins-FCD Prod-331 a335b1a6d1e9c32173c9534e6f6ff51494143916