Faculty Collaboration Database

Ventral medullary surface activity during sleep, waking, and anesthetic states in the goat. Am J Physiol 1994 Oct;267(4 Pt 2):R1154-60

Date

10/01/1994

Pubmed ID

7943426

DOI

10.1152/ajpregu.1994.267.4.R1154

Scopus ID

2-s2.0-0028073547 (requires institutional sign-in at Scopus site)   19 Citations

Abstract

We examined activity, measured as changes in reflected light, from the surface of a rostral ventral medullary area that is involved in cardiorespiratory control. We collected images during sleep and waking states and during halothane anesthesia in five adult unrestrained goats. During quiet sleep, overall activity increased and overall variability decreased compared with waking levels, whereas rapid eye movement sleep increased variability, and average activity decreased to near-waking levels. Distinct regions of activation and suppression appeared during sleep states. Deep anesthesia decreased activity and minimized variation. We speculate that alterations in rostral ventral medullary surface activity may play a role in state-dependent changes in cardiorespiratory control mechanisms.

Author List

Rector DM, Gozal D, Forster HV, Ohtake PJ, Pan LG, Lowry TF, Harper RM

Author

Hubert V. Forster PhD Professor in the Physiology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Activity Cycles
Anesthesia, General
Animals
Goats
Halothane
Medulla Oblongata
Sleep
Sleep Stages
Sleep, REM
Wakefulness