Near-infrared spectroscopy in the critical setting. Pediatr Emerg Care 2011 May;27(5):432-9; quiz 440-2
Date
05/07/2011Pubmed ID
21546812DOI
10.1097/PEC.0b013e3182188442Scopus ID
2-s2.0-79955796945 (requires institutional sign-in at Scopus site) 37 CitationsAbstract
Near-infrared spectroscopy is a noninvasive means of determining real-time changes in regional oxygen saturation of cerebral and somatic tissues. Hypoxic neurologic injuries not only involve devastating effects on patients and their families but also increase health care costs to the society. At present, monitors of cerebral function such as electroencephalograms, transcranial Doppler, jugular bulb mixed venous oximetry, and brain tissue oxygenation monitoring involve an invasive procedure, are operator-dependent, and/or lack the sensitivity required to identify patients at risk for cerebral hypoxia. Although 20th century advances in the understanding and management of resuscitation of critically ill and injured children have focused on global parameters (ie, pulse oximetry, capnography, base deficit, lactate, etc), a growing body of evidence now points to regional disturbances in microcirculation that will lead us in a new direction of adjunctive tissue monitoring and response to resuscitation. In the coming years, near-infrared spectroscopy will be accepted as a way for clinicians to more quickly and noninvasively identify patients with altered levels of cerebral and/or somatic tissue oxygenation and, in conjunction with global physiologic parameters, guide efficient and effective resuscitation to improve outcomes for critically ill and injured pediatric patients.
Author List
Drayna PC, Abramo TJ, Estrada CAuthor
Patrick C. Drayna MD Associate Professor in the Pediatrics department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Critical IllnessHumans
Intensive Care Units
Reproducibility of Results
Spectroscopy, Near-Infrared