Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Metrizamide optic nerve sheath opacification. Invest Radiol 1980;15(4):343-5

Date

07/01/1980

Pubmed ID

7203895

DOI

10.1097/00004424-198007000-00012

Scopus ID

2-s2.0-0018961991 (requires institutional sign-in at Scopus site)

Abstract

The safety of metrizamide in the optic nerve sheath has not been studied to our knowledge. We studied histologic changes produced by metrizamide in the optic nerve of cats with surgically created lesions simulating orbital tumors and trauma. Displacement, compression, and disruption of the optic nerve sheath were detectable by radiographing the opacified sheath. Arachnoiditis of the optic nerve sheath is unlikely from a single exposure to metrizamide in a concentration less than 300mg I/ml.

Author List

Haughton VM, Davis JP, Harris GJ, Ho KC

Author

Gerald J. Harris MD Professor in the Ophthalmology and Visual Sciences department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Animals
Cats
Metrizamide
Myelin Sheath
Optic Nerve
Radiography