Long-term frequent plasma exchange donation of cryoprecipitate. Transfusion 1988;28(4):307-10
Date
07/01/1988Pubmed ID
3133843DOI
10.1046/j.1537-2995.1988.28488265254.xScopus ID
2-s2.0-0023680980 (requires institutional sign-in at Scopus site) 18 CitationsAbstract
Plasma exchange donation accomplishes the selective donation of cryoprecipitate. It facilitates the repeated donation of large quantities of factor VIII by individual donors and reduces donor exposure for recipients. A highly motivated donor is described who has undergone 103 donations between May 1983 and March 1987, producing 359,460 IU of factor VIII and supplying all the factor VIII needed since August 1983 by his severely affected hemophiliac son, now age 14. The donor has remained in good health, and no significant abnormalities have been noted in hematologic, biochemical, immunologic, coagulation, and serum protein testing. Extensive experience with this donor suggests that repeated plasma-exchange donation is safe and can sometimes allow single-donor support of severe hemophiliacs.
Author List
McLeod BC, Sassetti RJ, Cole ER, Scott JPMESH terms used to index this publication - Major topics in bold
AdolescentAdult
Blood Donors
Factor VIII
Fibrinogen
Hemophilia A
Humans
Male
Plasma Exchange
Time Factors
