Mitogenicity of cell wall fractions of Micropolyspora faeni. Ann Allergy 1978 Jan;40(1):12-4
Date
01/01/1978Pubmed ID
623390Scopus ID
2-s2.0-0017891070 (requires institutional sign-in at Scopus site) 5 CitationsAbstract
Cell wall fractions of Micropolyspora faeni, a causative agent of hypersensitivity pneumonitis, have been shown to possess non-specific mitogenic activity for guinea pig, rabbit and human lymphocytes. This activity was unrelated to endotoxin and may not be associated with peptidoglycan. This lymphocyte proliferation stimulus may play a role in the adjuvant properties of this organism and in the etiology of hypersensitivity lung disease.
Author List
Smith SM, Hill JO, Snyder IS, Burrell RMESH terms used to index this publication - Major topics in bold
AnimalsCell Wall
Guinea Pigs
Limulus Test
Lymphocyte Activation
Lymphocytes
Micromonosporaceae
Mitogens
Muramic Acids
Rabbits
Spleen
