The spectrum of Epstein-Barr virus hepatitis in children. Pediatr Pathol 1986;5(3-4):337-51
Date
01/01/1986Pubmed ID
3024140DOI
10.3109/15513818609068860Scopus ID
2-s2.0-0022502442 (requires institutional sign-in at Scopus site) 15 CitationsAbstract
The clinical and pathologic features of Epstein-Barr virus (EBV) hepatitis in 3 children are described. Manifestations included fever, hepatomegaly, disseminated intravascular coagulation, and failure of uptake of technetium by the reticuloendothelial system of the liver. Histologic features may mimic chronic active hepatitis and lymphoid malignancy. Two patients underwent exploratory laparotomy because of suspected tumor. Recognition of the wide spectrum of hepatic involvement in infectious mononucleosis is important in the differential diagnosis of hepatomegaly. Diagnosis should be made by measurement of IgM-specific EBV antibodies.
Author List
Lloyd-Still JD, Scott JP, Crussi FMESH terms used to index this publication - Major topics in bold
ChildChild, Preschool
Diagnosis, Differential
Female
Hepatitis, Viral, Human
Herpesvirus 4, Human
Humans
Infectious Mononucleosis
Liver
Male
Microscopy, Electron
Mononuclear Phagocyte System
Technetium
