Current therapy and new perspectives in the treatment of medulloblastoma. Pediatr Neurol 1998 Feb;18(2):103-15
Date
04/16/1998Pubmed ID
9535295DOI
10.1016/s0887-8994(97)00221-xScopus ID
2-s2.0-0032007054 (requires institutional sign-in at Scopus site) 47 CitationsAbstract
Medulloblastoma, a malignant tumor arising from the medullary velum, is the most common malignant brain tumor of childhood. Local extension into the cerebellar hemisphere, infiltration of the floor of the fourth ventricle, and seeding into the subarachnoid space are common. Early diagnosis and improved treatment consisting of surgery followed by radiation and chemotherapy for selected high-risk patients has contributed to a dramatic change in survival. This article reviews current treatment strategies and describes new therapies that have the potential to improve the outlook of children with medulloblastoma.
Author List
Whelan HT, Krouwer HG, Schmidt MH, Reichert KW, Kovnar EHMESH terms used to index this publication - Major topics in bold
Cerebellar NeoplasmsChemotherapy, Adjuvant
Child
Child, Preschool
Developmental Disabilities
Female
Humans
Male
Medulloblastoma
Phototherapy
Radiotherapy, Adjuvant
Treatment Outcome