Predictability of acute radiation injury severity. Health Phys 2008 Mar;94(3):255-63
Date
02/28/2008Pubmed ID
18301099DOI
10.1097/01.HP.0000290833.66789.dfScopus ID
2-s2.0-41049091534 (requires institutional sign-in at Scopus site) 22 CitationsAbstract
Results of dose-response analyses for different clinical symptoms of acute radiation syndrome (ARS) are reported here. The analyses were performed on dosimetric and clinical data from a group of ARS patients (59 cases) exposed to gamma and neutron or gamma radiation alone due to nuclear accidents at Mayak Production Association (Mayak PA). Findings suggested the possibility of prediction of injury severity within the first hours or days after acute exposure based on clinical symptoms and signs such as the onset of vomiting, neutrophil count abnormalities in the peripheral blood within the first 2-3 hours after acute exposure, and lymphocyte count abnormalities in the peripheral blood within the first 24-48 h after acute exposure.
Author List
Azizova TV, Osovets SV, Day RD, Druzhinina MB, Sumina MV, Pesternikova VS, Teplyakov II, Zhang A, Kuniak M, Vasilenko EK, Wald N, Slaughter DM, Okladnikova ND, Schall LCAuthor
Laura Cassidy PhD Associate Dean, Professor in the Institute for Health and Equity department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AlgorithmsEnvironmental Exposure
Humans
Prevalence
Proportional Hazards Models
Radiation Injuries
Reproducibility of Results
Risk Assessment
Risk Factors
Russia
Sensitivity and Specificity
Severity of Illness Index