Radiation-associated liver injury. Int J Radiat Oncol Biol Phys 2010 Mar 01;76(3 Suppl):S94-100
Date
03/05/2010Pubmed ID
20171524Pubmed Central ID
PMC4388033DOI
10.1016/j.ijrobp.2009.06.092Scopus ID
2-s2.0-76449115024 (requires institutional sign-in at Scopus site) 559 CitationsAbstract
The liver is a critically important organ that has numerous functions including the production of bile, metabolism of ingested nutrients, elimination of many waste products, glycogen storage, and plasma protein synthesis. The liver is often incidentally irradiated during radiation therapy (RT) for tumors in the upper- abdomen, right lower lung, distal esophagus, or during whole abdomen or whole body RT. This article describes the endpoints, time-course, and dose-volume effect of radiation on the liver.
Author List
Pan CC, Kavanagh BD, Dawson LA, Li XA, Das SK, Miften M, Ten Haken RKMESH terms used to index this publication - Major topics in bold
HumansLiver
Liver Neoplasms
Models, Biological
Radiation Dosage
Radiation Injuries
Radiation Tolerance
Risk