Two- and three-dimensional high-resolution imaging of the human oviduct with optical coherence tomography. Fertil Steril 1998 Jul;70(1):155-8
Date
07/11/1998Pubmed ID
9660439DOI
10.1016/s0015-0282(98)00097-1Scopus ID
2-s2.0-0032124889 (requires institutional sign-in at Scopus site) 43 CitationsAbstract
OBJECTIVE: To evaluate the feasibility of optical coherence tomography, a new method of micron-scale imaging, for high-resolution assessment of the oviduct. Optical coherence tomography is analogous to ultrasound except that it measures the backreflection of infrared light rather than acoustical waves.
DESIGN: The ampulla of a human fallopian tube was imaged in vitro using optical coherence tomography. Images were generated in 2 and 3 dimensions.
SETTING: University.
PATIENT(S): Samples were obtained from women who had undergone hysterectomy for leiomyomatosis.
INTERVENTION(S): None
MAIN OUTCOME MEASURE(S): The ability to perform imaging on a micron scale, which is a level of resolution higher than that of any currently available clinical technology.
RESULT(S): Two- and three-dimensional data sets of the reflectance of a human fallopian tube were acquired. A volume of 5 x 5 x 2.5 mm (length x width x depth) was scanned. The axial resolution was 11 microm, and the lateral resolution at the focus was 20 microm. The data sets showed detailed structures of the fallopian tube.
CONCLUSION(S): Our ability to obtain micron-scale two- and three-dimensional images of an in vitro oviduct suggests that it may be possible to identify and surgically treat tubal causes of infertility.
Author List
Herrmann JM, Brezinski ME, Bouma BE, Boppart SA, Pitris C, Southern JF, Fujimoto JGMESH terms used to index this publication - Major topics in bold
Diagnostic ImagingEndoscopy
Fallopian Tubes
Female
Humans
Image Processing, Computer-Assisted
Infrared Rays
Tomography
Ultrasonography
