Hematopoietic stem cell transplantation for severe aplastic anemia. Curr Opin Hematol 1998 Nov;5(6):441-4
Date
11/14/1998Pubmed ID
9814653DOI
10.1097/00062752-199811000-00015Scopus ID
2-s2.0-0031593816 (requires institutional sign-in at Scopus site) 2 CitationsAbstract
Severe aplastic anemia (SAA) appears to be an immunologically mediated disorder that results in deficient and defective hematopoietic stem cells. Both immune suppression and hematopoietic stem cell transplantation provide effective treatment for SAA. Optimal choice between these therapies depends upon a complex interaction of patient age, disease severity, overall patient health, and donor availability. Recent publications provide additional information on the long-term efficacy and toxicity of both treatments. Prospective studies with long-term follow-up are needed to put these and newer treatments in proper perspective.
Author List
Margolis DA, Cammita BMAuthor
David A. Margolis MD Chair, Professor in the Pediatrics department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Anemia, AplasticBlood Donors
Hematopoietic Stem Cell Transplantation
Humans
Survival Rate