A cDNA from human bone marrow encoding a protein exhibiting homology to the ATP1gamma1/PLM/MAT8 family of transmembrane proteins. Biochim Biophys Acta 2001 Jan 26;1517(2):307-10
Date
05/09/2001Pubmed ID
11342114DOI
10.1016/s0167-4781(00)00251-7Scopus ID
2-s2.0-0035951666 (requires institutional sign-in at Scopus site) 2 CitationsAbstract
A cDNA clone, IWU-1, was cloned from human bone marrow. Its putative open reading frame encoded a protein of 115 amino acids with a calculated molecular mass of 12.9 kDa. The deduced amino acid sequence exhibited high homology (>68%) to members of the ATP1gamma1/PLM/MAT8 family of single transmembrane proteins, primarily in the region containing the putative transmembrane domain. The sequence at the amino-terminal side exhibited high homology (>61%) to the cytoplasmic region of the angiotensin II type 1 receptors.
Author List
Omasa T, Chen YG, Mantalaris A, Wu JHAuthor
Yi-Guang Chen PhD Professor in the Pediatrics department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Amino Acid SequenceBase Sequence
Bone Marrow
Cloning, Molecular
Consensus Sequence
Culture Techniques
DNA, Complementary
Humans
Membrane Proteins
Molecular Sequence Data
Receptor, Angiotensin, Type 1
Receptor, Angiotensin, Type 2
Receptors, Angiotensin
Reverse Transcriptase Polymerase Chain Reaction
Sequence Alignment
Sequence Homology