Hospital admission for acute painful episode following methacholine challenge in an adolescent with sickle cell disease. Pediatr Pulmonol 2009 Jul;44(7):728-30
Date
06/09/2009Pubmed ID
19504562Pubmed Central ID
PMC3729266DOI
10.1002/ppul.21049Scopus ID
2-s2.0-67650138477 (requires institutional sign-in at Scopus site) 9 CitationsAbstract
Asthma is associated with increases in sickle cell disease (SCD)-related morbidity and mortality. A thorough evaluation for asthma in children with SCD is important and may involve methacholine challenge (MCh). In this report, we present a 14-year-old male with SCD who was admitted for an acute painful episode following MCh. Pain events after MCh have not been previously reported in children with SCD. The risk-benefit ratio should be strongly considered prior to performance of MCh in this patient population, and all possible complications, including an acute painful episode, should be openly discussed with the parents and pediatric patient.
Author List
Knight-Perry JE, Field JJ, Debaun MR, Stocks J, Kirkby J, Strunk RCAuthor
Joshua J. Field MD Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdolescentAnemia, Sickle Cell
Asthma
Bronchial Provocation Tests
Bronchoconstrictor Agents
Chest Pain
Humans
Male
Methacholine Chloride
